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Lendert Gelens

@lendertgelens.bsky.social
309 followers 426 following 33 posts

Part-time physicist-turned-biologist studying early embryos and the cell cycle @KU Leuven, full-time dad to two active boys. Visualizing academic data trends in Flanders. www.gelenslab.org | academic-compass.be/en

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Reposted by Lendert Gelens
Ulrich Schwarz @ulrichschwarz.bsky.social · 24/09/2026
Our summer academy on "Science and Histories of Fever" is in full swing at the Marsilius Kolleg, with great talks from e.g. @kakape.bsky.social, @feverprojecthd.bsky.social and @lendertgelens.bsky.social. If you are around, join us for "Marsilius Kontrovers" tonight at 7 pm: tinyurl.com/y8dkkxw4
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Mike Dorrity @mwdorr.bsky.social · 13/09/2026
🧫 We’re hiring a staff/research scientist to develop new experimental approaches that capture cell state dynamics. Join us in Heidelberg, details + application here: embl.wd103.myworkdayjobs.com/EMBL/job/Hei... Closes September 30th
embl.wd103.myworkdayjobs.com
Laboratory Officer
The Dorrity group at EMBL Heidelberg is seeking a motivated and skilled molecular biologist to join as a Laboratory Officer. Our group uses cutting-edge single-cell genomic techniques to study how cel...
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The Ramsey Lab @theramseylab.bsky.social · 10/08/2026
New 📄 🚨! #CellBio is teeming with simulations comprising an extraordinarily high number of components. We argue that model complexity will not automatically lead to a better understanding of biological systems & discuss how modeling practices could be repurposed: arxiv.org/abs/2608.06998 #philsci
arxiv.org
Simulating is not always understanding: When model complexity obscures biology
In cell biology, computational models of biological systems range from minimal representations with a handful of parameters to whole-cell simulations tracking thousands of molecular species across a c...
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Philip Ball @philipcball.bsky.social · 10/08/2026
"The central challenge is no longer building models that reproduce biological behavior, but building models from which causal structure can be inferred." Very sensible paper about not just throwing everything into your simulation or model. arxiv.org/abs/2608.06998
arxiv.org
Simulating is not always understanding: When model complexity obscures biology
In cell biology, computational models of biological systems range from minimal representations with a handful of parameters to whole-cell simulations tracking thousands of molecular species across a c...
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Lendert Gelens @lendertgelens.bsky.social · 23/06/2026
Exciting work! 👏🏼
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Ulrich Schwarz @ulrichschwarz.bsky.social · 23/05/2026
Fever - friend or foe? Happy to announce our International Marsilius Academy Feel the Heat – Science and Histories of Fever 📅 20–25 September 2026 | Marsilius Kolleg, Heidelberg ⏰ Application deadline: 14 June 2026 👉 More information and application: lnkd.in/eEmXDYgZ
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Lendert Gelens @lendertgelens.bsky.social · 17/04/2026
Temperature affects all biological rates, but how do we model its effects? Our 2-part review brings together modeling approaches from empirical curve fits to microscopic kinetics to network-level dynamics 🧵 Part I: doi.org/10.1016/j.coisb.2026.100577 Part II: doi.org/10.1016/j.coisb.2026.100578
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EMBL Events @events.embl.org · 09/01/2026
⏰ Deadline extension for #EESBioOsc ⏰ You now have until 14 January to submit your abstract for the EMBO | EMBL Symposium 'Biological oscillators: rhythms and synchronisation across scales'! 👉 s.embl.org/ees26-04-bl
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Reposted by Lendert Gelens
Brugues Lab @brugueslab.bsky.social · 07/01/2026
Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de
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The Ramsey Lab @theramseylab.bsky.social · 08/12/2025
Come work with us! We are looking for a postdoc in #philbio or #philphysics to work on an interdisciplinary project that adopts the lens of self-organization & active matter to explore the boundary between living & nonliving systems www.kuleuven.be/personeel/jo... #academicsky #philjobs #HPS #evosky
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Nikita Frolov 🇺🇦 @nikitaphysics.bsky.social · 22/10/2025
🚨 Late preprint alert! Why do biological process rates scale nonlinearly with temperature, deviating from the straight line on an Arrhenius plot? The key may lie in their inherent complexity! More in thread and here: doi.org/10.1101/2025...
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Jan Rombouts @janrombouts.bsky.social · 18/09/2025
Please allow me to introduce... our new preprint 🎉 Together with Michael Zhao, Anna Erzberger and Alexander Aulehla, we investigate pattern formation due to aggregation in confined systems. You can find it at arxiv.org/abs/2509.08533 @michaelzhao.bsky.social @erzbergerlab.bsky.social
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Lendert Gelens @lendertgelens.bsky.social · 18/09/2025
Looking forward to it!!
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Zena Hadjivasiliou @zenahadjivasiliou.bsky.social · 16/09/2025
Fresh from the press💥 We asked what happens when you evolve gene regulatory networks computationally at scale. Do general principles of GRN evolution jump out? Is the process predictable? Read on to find out @prxlife.bsky.social @crick.ac.uk @ucl-ipls.bsky.social 👉 journals.aps.org/prxlife/abst...
journals.aps.org
Gene Network Organization, Mutation, and Selection Collectively Drive Developmental Pattern Evolvability and Predictability
The historical order in which mutations appear during evolution determine the evolutionary trajectory of gene regulatory networks and influence how developmental patterns change and diversify over tim...
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Stem Cell Podcast @stemcellpodcast.com · 04/06/2025
Drs. Borzo Gharibi, Silvia Santos, and a team at @crick.ac.uk generated an ESC-derived 3D model of the post-gastrulation #amnion. 📄 @cellpress.bsky.social - bit.ly/45bJs0c 🎤 bit.ly/4kE4eKf
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Lendert Gelens @lendertgelens.bsky.social · 03/09/2025
🧵Why do early embryonic cell cycles speed up with temperature almost like simple chemical reactions, but not quite? 🌡️ Across frogs, fish, worms, and flies we found a shared scaling law, and uncovered why deviations from Arrhenius behavior emerge. 👉 doi.org/10.1038/s41467-025-62918-0
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Lendert Gelens @lendertgelens.bsky.social · 02/09/2025
🧵Does the nucleus set the cell cycle clock? 🕒 In frog egg extract “mini-cells” we see that as nuclei grow, cycles slow down. The period scales with the nuclear-to-cytoplasmic ratio, across Xenopus species, and even when DNA replication or transcription are blocked. 👉 doi.org/10.1016/j.cu...
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Jan Rombouts @janrombouts.bsky.social · 29/08/2025
Many years in the making but now finally online! What determines the temperature scaling and thermal limits of cell cycle duration in embryos? We tackled the question using a combination of dynamical systems analysis and experimental measurements in embryos and in cycling Xenopus extracts.
A plot showing the duration of the early embryonic cell cycle of 5 different species as a function of temperature. Higher temperatures mean faster cycles, up to an optimum, beyond which the cycles slow down and eventually stop.
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Lendert Gelens @lendertgelens.bsky.social · 03/06/2025
BOOM💥Martina was on fire at the recent #Biologists100 meeting on Liverpool, sharing her research on cell cycle oscillations. #proudPI
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Simone Reber @simonereber.bsky.social · 19/05/2025
✨We are looking for a PhD student interested in physical cell bio, imaging 🔬, biochemistry, #Xenopus 🐸 & #microtubules ✨ Join us @mpiib-berlin.mpg.de!
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James Briscoe @jamesbriscoe.bsky.social · 15/05/2025
Beautiful work from @santoslab.bsky.social A 3D model of human amnion from hESCs These recapitulate amniotic sac development, revealing GATA3 as key amniogenesis driver & autoregulatory BMP/Wnt feedback loops And check out the size of them in the video www.cell.com/cell/fulltex...
cell.com
Post-gastrulation amnioids as a stem cell-derived model of human extra-embryonic development
An embryonic stem cell-based 3D model that accurately recapitulates the size, morphology, and functional features of the human amnion at 4 weeks, termed the post-gastrulation amnioid (PGA), is develop...
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EMBL Events @events.embl.org · 09/05/2025
We can't believe #EESTCBio is over! 😱 Thank you to the organisers, speakers, and participants for creating such a vibrant space for critical thinking. It was a joy to see you exchange ideas, challenge assumptions, and explore new perspectives 💡 We hope to see you again at the next edition! 👋
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the Node @the-node.bsky.social · 20/02/2025
3️⃣"Physics of the Early Embryonic Divisions Workshop – Microtubules, energy and cell fate decisions in early embryogenesis" by @olgaafonso.bsky.social, @shuzokato.bsky.social & Helena Cantwell thenode.biologists.com/physics-of-t... Thank you to everyone who wrote these reports! (3/3🧵)
thenode.biologists.com
Physics of the Early Embryonic Divisions Workshop – Microtubules, energy and cell fate decisions in early embryogenesis - the Node
Text written by Olga Afonso, Helena Cantwell, and Shuzo Kato This is one of three reports about the "Physics of the Early Embryonic Divisions" Workshop,
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the Node @the-node.bsky.social · 20/02/2025
2️⃣ "Physics of the Early Embryonic Cell Divisions: Feedbacks, Flows and Information" by Claudio Hernández-López and @singh29aditya.bsky.social thenode.biologists.com/physics-of-t... (2/3🧵)
thenode.biologists.com
Physics of the Early Embryonic Cell Divisions: Feedbacks, Flows and Information - the Node
By Claudio Hernández-López and Aditya Singh Rajput This is one of three reports about the "Physics of the Early Embryonic Divisions" Workshop, organised
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the Node @the-node.bsky.social · 20/02/2025
Last year, 30 developmental biologists and biophysicists got together for the 'Physics of the Early Embryonic Cell Divisions' Workshop. Find out what happened (1/3🧵) 1️⃣Building Bridges Between Biology and Physics by @irene-yuting-li.bsky.social @isaacsiuwong.bsky.social & @lena-schindler.bsky.social
thenode.biologists.com
Building Bridges Between Biology and Physics: Insights from a Workshop on Early Embryonic Cell Divisions - the Node
Written by Irene Li, Magdalena Schindler and Isaac Wong This is one of three reports about the "Physics of the Early Embryonic Divisions" Workshop,
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Berta Verd @bertaverd.bsky.social · 05/02/2025
I am recruiting an #ERC funded PostDoc to work on the evolution of vertebral counts in cichlids. This is an experimental project & will be looking for candidates with experience generating reporter lines, live-imaging and experimental embryology. Application deadline: 25th Feb. tinyurl.com/33jbu8fa
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Nicolas Minc @minclab.bsky.social · 03/01/2025
Our lab has multiple open positions for post-docs to study the regulation and function of cytoplasm mechanics during embryo development. Details below 👇👇 Please Repost !!! @ijmonod.bsky.social @cnrs.bsky.social
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Lendert Gelens @lendertgelens.bsky.social · 03/02/2025
🐸 are 🆒! ❄️☀️
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Lendert Gelens @lendertgelens.bsky.social · 03/01/2025
Really looking forward to this visit, great way to start the year! Thank you @meiosis-mom.bsky.social for inviting me!
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Lendert Gelens @lendertgelens.bsky.social · 24/12/2024
Cell cycles at double speed? Looks like those frogs are spiraling into party mode, happy xmas!
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Lendert Gelens @lendertgelens.bsky.social · 15/11/2024
Had a great time this week with a wonderful group of researchers at our workshop on the physics of early embryonic cell divisions! Big thanks to everyone there, i.e. Johanna, Frank, Laura and Adam from @biologists.bsky.social, and to my co-organizer @kamenzlab.bsky.social! Let’s do this again!
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Lendert Gelens @lendertgelens.bsky.social · 14/11/2024
Hi #SciSky! I’ve been hearing great things about you, happy to have this alternative to X/Twitter. Looking forward to seeing lots of fascinating science!
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