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Janelia Research Campus

@hhmijanelia.bsky.social
3.2K followers 261 following 219 posts

HHMI’s Janelia Research Campus in Ashburn, Virginia, is innovating research practices and technologies to solve biology’s deepest mysteries. www.janelia.org

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HHMI @hhmi-science.bsky.social · 24/12/2025
Our kind of annual tradition: Glucose + Tollens’ reagent + festive swirling = a chemical reaction that creates a thin layer of silver, loads of seasonal cheer, & ornaments worthy of being passed down for ... well, a few weeks at least. Happy holidays to all those who celebrate! ✨
Someone holds a finished ChemisTree ornamentResearchers at HHMI Janelia's Research Campus make ChemisTree ornamentsResearchers at HHMI Janelia's Research Campus make ChemisTree ornamentsChemisTree ornament on a tree
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Reposted by Janelia Research Campus
HHMI @hhmi-science.bsky.social · 17/12/2025
“I feel being part of their life, being part of their career, is just priceless.” — HHMI Investigator Xin Chen, '25 Summer Undergraduate Research Program mentor 🧪 Rising junior or senior? Applications close 11:59pm Dec. 22! Explore a career in biological or biomedical research: bit.ly/CechFellows
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Reposted by Janelia Research Campus
HHMI @hhmi-science.bsky.social · 16/12/2025
(1/2): What if the bacteria living in our digestive tracts could produce compounds that help us live longer? The Wang (Meng) Lab at HHMI's Janelia Research Campus has found a way to get gut microbes to produce metabolites that promote longevity in animals: hhmi.news/48QyPAm.
Image: The bacteria shown in red produce colanic acid and display fewer signs of aging.

Credit: Meng Wang
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Janelia Research Campus @hhmijanelia.bsky.social · 15/12/2025
Apply by Feb. 3 to become a Janelia Group Leader! Group Leaders drive breakthroughs & experimental approaches in imaging, molecular engineering, protein chemistry, mass spectrometry, & methods that don't yet exist. Learn more: janelia.org/groupleader 🧪
Lead a lab at Janelia

Pioneer next-generation tools for biological discovery

Apply by Feb. 3, 2026
janelia.org/groupleader
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Reposted by Janelia Research Campus
HHMI @hhmi-science.bsky.social · 05/12/2025
(1/2): Using cryo-electron tomography and an instrument like this one, HHMI Investigator Michael Rosen & team (not pictured) have captured the most detailed images to date of the molecules inside chromatin condensates. hhmi.news/4iFBIrV
A cryo-EM instrument at Janelia
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HHMI @hhmi-science.bsky.social · 18/11/2025
Calling all rising juniors & seniors: Interested in biological or biomedical research? Applications for our ’26 Summer Undergraduate Research Experience Program are now open! Nine weeks, hands-on research, & mentorship from some of the nation’s top scientists — learn more: bit.ly/CechFellows
bit.ly
Summer Undergraduate Research Experience | HHMI
The Cech Fellows Program is a paid, nine-week summer research experience empowering the next generation of scientific leaders.
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Janelia Research Campus @hhmijanelia.bsky.social · 03/11/2025
ICYMI: A team of researchers unveiled the complete connectome of an entire male fruit fly central nervous system, encompassing the central brain, optic lobes, and ventral nerve cord. hhmi.news/4o3EJnk
hhmi.news
Researchers reveal connectome of the male fruit fly central nervous system
A team of researchers at HHMI's Janelia Research Campus has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of...
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Reposted by Janelia Research Campus
Luke Lavis @rhodamine110.bsky.social · 27/10/2025
A new, nerdy paper. We figured out (some) of the rules underlying cell-permeability of probes and designed ligands that light up, grab, and move proteins around. Awesome @hhmijanelia.bsky.social x @uwmadison.bsky.social x @stjuderesearch.bsky.social collaboration! www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Janelia Research Campus @hhmijanelia.bsky.social · 23/10/2025
Join the team at Janelia to use #theory, computation, and modeling to tackle bold questions in #biology. Collaborate across scientific disciplines to drive discovery. Apply by Nov. 3 @ janelia.link/theoryfellowprogram #computationalbiology #sciencecareers
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Catherine (Katie) Schretter @ceschretter.bsky.social · 23/10/2025
Excited to announce our new pre-print (www.biorxiv.org/cgi/content/...)! This collaborative work (co-led by Adriane Otopalik and Gerry Rubin) examines how neuronal circuits regulate social behaviors, like courtship🫶 and aggression🥊, across sexes. #neuroscience #Drosophila #WomenInSTEM 🧪1/
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Janelia Research Campus @hhmijanelia.bsky.social · 21/10/2025
🦠 New research provides a mechanism for understanding how environmental changes to somatic cells are passed through the germline, helping scientists better understand transgenerational effects, like the malnutrition of a parent affecting its offspring. hhmi.news/4mCD3QO
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Reposted by Janelia Research Campus
Champalimaud Research @champalimaudr.bsky.social · 17/10/2025
🪰 Srinivas Turaga @hhmijanelia.bsky.social opened #CRSy25 Day 3’s afternoon session with “Simulating the brain and body of the fruit fly” From detailed connectomes to full-body physics, they model how neural circuits generate flight & walking - bridging the gap between brain structure and behaviour.
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Janelia Research Campus @hhmijanelia.bsky.social · 16/10/2025
🌟 Apply to lead a lab at Janelia 🌟 We’re #hiring Group Leaders in our Computation & Theory research area. 🔹 5-year renewable appointment 🔹 Internal funding + generous resources 🔹 Collaboration across disciplines 📅 Apply by Nov. 4 👉 janelia.link/groupleader
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Janelia Research Campus @hhmijanelia.bsky.social · 15/10/2025
🎉 Congrats to Research Scientist Igor Siwanowicz: 5th & 8th place in the 2025 Nikon Small World Photomicrography Competition for his images of spores of a small tropical fern & mallow pollen germinating on stigma while being parasitized by a filamentous fungus. hhmi.news/491e0Uf
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Champalimaud Research @champalimaudr.bsky.social · 15/10/2025
Opening talk: 🧠🐟 How does the whole brain coordinate learning, memory & movement? @mishaahrens.bsky.social @hhmijanelia.bsky.social unveils whole-brain imaging in zebrafish exploring how neural & body dynamics shape behaviour and adaptation.
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Janelia Research Campus @hhmijanelia.bsky.social · 14/10/2025
🧞Like its namesake, Janelia’s GENIE Project Team makes wishes come true. Luckily for biologists, this genie doesn’t grant just 3 requests. 🧪Learn about how GENIE has accelerated the development of best-in-class sensors for measuring neuronal activity. hhmi.news/4gFqwKX
hhmi.news
Unleashing the GENIE: Janelia's Project Team develops state-of-the-art sensors for biological research
For more than a decade, the GENIE Project Team at HHMI's Janelia Research Campus has collaborated with the research campus's tool developers and tool users to take innovative biological sensors from novel prototypes to widely used laboratory staples--a ...
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Janelia Research Campus @hhmijanelia.bsky.social · 13/10/2025
🧠 A new wiring diagram of the 166,000+ neurons in the brain & nerve cord of a male fruit fly is a key tool in uncovering how the brain enables complex behavior—information that could ultimately help scientists better understand what causes different diseases ➡️ hhmi.news/4o3EJnk
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Reposted by Janelia Research Campus
Rachel Lee, PhD @scientistrachel.bsky.social · 12/10/2025
Today marks 4 years of enjoying the beautiful @hhmijanelia.bsky.social campus 🌳
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Janelia Research Campus @hhmijanelia.bsky.social · 09/10/2025
📢Apply by Dec. 3 for our joint graduate programs with the Johns Hopkins University School of Medicine in neuroscience & cross-disciplinary biology. 🧠Develop interdisciplinary research projects 🌍Join a collaborative environment 🔬Leverage shared resources & support teams ➡️ janelia.org/graduate
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Janelia Research Campus @hhmijanelia.bsky.social · 07/10/2025
🔊 Listen to Senior Group Leader Hari Shroff discuss microscopy, biology and his path through science in the latest episode of Ashoka University's The Science of It podcast: www.youtube.com/watch?v=dyoP5HwAFAc…
youtube.com
The Science of Microscopy | Innovator Hari Shroff | The Science of It Ep. 4
Microscopist Hari Shroff takes us deeper into the world of nature's tiniest beings in the latest episode of Ashoka University's #TheScienceofIt podcast. What made a computer scientist and physicist turn to building microscopes to explore the beauty of ...
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Reposted by Janelia Research Campus
Laura Grima @lauragrima.bsky.social · 07/10/2025
Pleased to have this review out in @cp-trendsneuro.bsky.social. In it we discuss various aspects of the intersection between foraging behaviors and neuroscience, and offer some future directions: www.sciencedirect.com/science/arti...
sciencedirect.com
Foraging as an ethological framework for neuroscience
The study of foraging is central to a renewed interest in naturalistic behavior in neuroscience. Applying a foraging framework grounded in behavioral …
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Janelia Research Campus @hhmijanelia.bsky.social · 06/10/2025
🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them. 🔗 hhmi.news/4o3EJnk
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Janelia Research Campus @hhmijanelia.bsky.social · 04/10/2025
Become a Theory Fellow @hhmijanelia.bsky.social 🧪 Work alongside experimentalists to test and refine theories 🎯 Receive mentorship from leading computational scientists 🔁 Contribute to Janelia’s cross-disciplinary research environment Apply by Nov. 3 @ janelia.link/theoryfellowprogram
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Janelia Research Campus @hhmijanelia.bsky.social · 01/10/2025
🥼 New research from the Wang Lab reveals a novel connection between lysosomes & the epigenome and provides new insights into how lysosomes regulate longevity over generations & drive the histone-based transfer of epigenetic information between cells. 🔗 hhmi.news/4mCD3QO
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Reposted by Janelia Research Campus
American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 27/09/2025
Plenary speaker spotlight ✨ Meng Wang (@bcmhouston.bsky.social / @hhmi.org) at #ASBMB26: “Racing the clock: Molecular mechanisms of aging.” ➡️Dive into the biochemical basis of aging, from metabolism to the genome: ow.ly/68i150X37Pm. #MakeItPossibble #AgingResearch #FutureOfScience
Text reads Plenary Speaker Meng Wang Professor, Baylor College of Medicine, HHMI. Racing the clock: molecular mechanisms of aging.  There is a photo of Meng Wang and the background is a scientific image behind a blue, pink and orange gradient.
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Janelia Research Campus @hhmijanelia.bsky.social · 26/09/2025
✨ ICYMI: Researchers detail how neurotransmitter receptors in the fly brain change during development ➡️ hhmi.news/4mFMhMY
hhmi.news
Researchers detail how neurotransmitter receptors in the fly brain change during development
New proteomics research is enabling scientists to decipher how neurotransmitter receptors behave and change as an organism develops. The new work could help scientists better understand the formation and function of synapses--the junctions where communi...
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Janelia Research Campus @hhmijanelia.bsky.social · 25/09/2025
🪱New research from the Wang Lab shows how changes in a worm’s lysosomes promoting longevity are transferred to its offspring through the epigenome, revealing how epigenetic modifications that help organisms cope with environmental stress can be inherited. 🔗 www.janelia.org/news/leaving...
janelia.org
Leaving a mark: New research shows how longevity is inherited across generations
New research from the Wang Lab reveals a novel connection between lysosomes & the epigenome and provides new insights into how lysosomes regulate longevity over generations & drive the histone-based t...
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Janelia Research Campus @hhmijanelia.bsky.social · 24/09/2025
🥼 Working with tool developers & support teams, Janelia’s GENIE Project Team recently created next generation sensors for detecting the neurotransmitters glutamate & GABA and adapted a new tool aimed at controlling & studying specific neural circuits in flies. 🔗 hhmi.news/4gFqwKX
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Janelia Research Campus @hhmijanelia.bsky.social · 19/09/2025
📢 Applications are open for the 4th installment of our ChemTools conference. We'll explore: 🧪 Platforms & tools for analyzing cell/tissue networks ⚡ Methods to perturb biological networks 🔍 Applications that yield new insights 🛏️ Lodging + meals covered ➡️ Apply by Dec 5: janelia.news/CHM26
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Reposted by Janelia Research Campus
Stephan Saalfeld @herrsaalfeld.bsky.social · 18/09/2025
We are looking for an #AIEngineer to help build protein language models that capture evolutionary constraints with @matsen.bsky.social and @jbloomlab.bsky.social at #AI@HHMI @hhmijanelia.bsky.social hhmi.wd1.myworkdayjobs.com/en-US/Extern...
hhmi.wd1.myworkdayjobs.com
AI Engineer - Evolutionary Protein Language Models
Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. Intro: AI@HHMI: HHMI is investing $500 million over the next 10 years ...
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Janelia Research Campus @hhmijanelia.bsky.social · 18/09/2025
🌟 Launch your own lab at Janelia 🌟 Advance our understanding of biology through theory, computational modeling & machine learning. 🔹 No teaching requirements 🔹 100% internally funded 🔹 Collaborate with expert support teams 📅 Apply by Nov. 4 👉 janelia.link/groupleader
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Janelia Research Campus @hhmijanelia.bsky.social · 16/09/2025
🧪For more than a decade, the GENIE Project Team has collaborated with tool developers & users to take innovative biological sensors from novel prototypes to widely used laboratory staples. Now, @janeliagenie.bsky.social is unveiling their latest collaborations. www.janelia.org/news/unleash...
janelia.org
Unleashing the GENIE: Janelia’s Project Team develops state-of-the-art sensors for biological research
For more than a decade, the GENIE Project Team at HHMI’s Janelia Research Campus has collaborated with the research campus’s tool developers and tool users to take innovative biological sensors from n...
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Janelia Research Campus @hhmijanelia.bsky.social · 12/09/2025
📢 Applications are open! Join us in May to explore computational simulation of biomechanical body models, bridging #neuroethology, #ML, physics simulation & computer vision. 🧠🤖 👁 🛏️ Lodging, meals & registration covered ➡️ Apply by Nov. 21 @ janelia.news/SIB26
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Janelia Research Campus @hhmijanelia.bsky.social · 09/09/2025
Become a Theory Fellow at Janelia. 🔍 Use computation & theory to tackle biological problems. 🖥️ Leverage state-of-the-art computational infrastructure 🤝 Collaborate across scientific disciplines Apply by Nov. 3 @ janelia.link/theoryfellowprogram
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Reposted by Janelia Research Campus
Misha Ahrens @mishaahrens.bsky.social · 08/09/2025
Preprint - Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo. www.biorxiv.org/content/10.1...
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Janelia Research Campus @hhmijanelia.bsky.social · 05/09/2025
📢 Conduct your PhD thesis research at Janelia. 🎓 Apply by Dec 3 for our joint graduate programs with Johns Hopkins School of Medicine in neuroscience & cross-disciplinary biology. 🌐 Collaborate across disciplines 🛠️ Work with tool builders 🤝 Train in a supportive environment ➡️ janelia.org/graduate
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Janelia Research Campus @hhmijanelia.bsky.social · 03/09/2025
Research detailing how nicotinic acetylcholine receptors—the main type of neurotransmitter receptor in the fly brain—change during development lays the groundwork for understanding the molecular composition, regulation & adaptability of these synapses➡️ hhmi.news/4mFMhMY
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Reposted by Janelia Research Campus
HHMI @hhmi-science.bsky.social · 28/08/2025
🎉Congratulations to David Baker, winner of the @royalsociety.org's Croonian Medal and Lecture for pioneering the design of completely new proteins and playing key roles in the development of protein structure prediction and protein engineering tools. 🔗 royalsociety.org/medals-and-p...
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Janelia Research Campus @hhmijanelia.bsky.social · 27/08/2025
🧪 New proteomics research is enabling scientists to decipher how neurotransmitter receptors behave & change as an organism develops, information that could help scientists better understand the formation & function of synapses.➡️ hhmi.news/4mFMhMY
janelia.org
Researchers detail how neurotransmitter receptors in the fly brain change during development
New proteomics research is enabling scientists to decipher how neurotransmitter receptors behave and change as an organism develops. The new work could help scientists better understand the formation and function of synapses--the junctions where communi...
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Janelia Research Campus @hhmijanelia.bsky.social · 26/08/2025
📢We're #hiring Group Leaders! Apply to lead a lab at Janelia & advance biology using theory, computational modeling & machine learning. 🔹5-year renewable appointment 🔹Pioneer new tools & approaches 🔹Collaborate across disciplines Apply by Nov. 4👉 janelia.link/groupleader
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Janelia Research Campus @hhmijanelia.bsky.social · 25/08/2025
❄️Time-deterministic cryo-optical microscopy, developed by researchers at the University of Osaka, Janelia & collaborating institutions, rapidly freezes live cells under an optical microscope, capturing a snapshot of cellular activity in high resolution➡️ hhmi.news/421MTUL
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HHMI @hhmi-science.bsky.social · 22/08/2025
Please join us in congratulating HHMI Investigators Jennifer Doudna (@jenniferdoudna.bsky.social) and David R. Liu, recipients of national awards from the American Chemical Society (@acs.org) for 2026.‬‬ 🔗 cen.acs.org/people/award...
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Andy Moore @aaandmoore.bsky.social · 18/08/2025
This is an airyscan confocal movie of mitochondria (white) moving around in a mouse astrocyte. Actin filaments are in orange and microtubules are in blue.
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Janelia Research Campus @hhmijanelia.bsky.social · 20/08/2025
🖥️ PEELing, a user-friendly platform developed by the Li Lab & Janelia’s Scientific Computing Software support team, allows researchers to analyze spatial proteomics data with the click of a mouse ➡️ hhmi.news/47FETwh
academic.oup.com
PEELing: an integrated and user-centric platform for spatially resolved proteomics data analysis
AbstractSummary. Molecular compartmentalization is vital for cellular physiology. Spatially resolved proteomics allows biologists to survey protein composi
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Janelia Research Campus @hhmijanelia.bsky.social · 19/08/2025
📷Happy #WorldPhotographyDay! 🎉To celebrate, we’re sharing a few macrophotography images taken by Janelia Research Specialist Igor Siwanowicz. 🔬Siwanowicz's images have placed 20+ times in the Nikon Small World & Olympus BioScapes competitions & were featured on US Postal Service stamps in 2023.
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Janelia Research Campus @hhmijanelia.bsky.social · 05/08/2025
✨ We’re #hiring Theory Fellows!✨ Janelia is recruiting early-career scientists to join our collaborative research environment and use #computation & #theory to tackle bold questions in #biology. 🔗 Apply by Nov. 3 👉 janelia.link/theoryfellow... @hhmi.org
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Janelia Research Campus @hhmijanelia.bsky.social · 01/08/2025
🧠 Scientists have struggled to build computational models simple enough to understand what individual neurons in the primary visual cortex are doing. 🖥️ Now, Janelia researchers are helping to solve that problem with a new class of simplified “minimodels.”
janelia.org
New computational model could help shed light on how we see
Researchers in the Stringer and Pachitariu labs at Janelia set out to create a simpler model to explain what’s going on in the primary visual cortex – the first stop in the brain for visual data.
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Janelia GENIE @janeliagenie.bsky.social · 29/07/2025
🧠🪰 New from GENIE @HHMIJanelia: far-red #RubyACRs from the Spudich Lab enable robust optogenetic inhibition in freely behaving #Drosophila — validated with ephys, imaging & behavior. 📄 Paper bit.ly/3H7S7af 🪰 Get flies bit.ly/41iVNwK med.uth.edu/bmb/spudich/ #OptoInhibition #FlyNeuro #FlyOptogenetics
Activation of RubyACRs in the pIP10 neuron suppressed pulse song of male flies during courtship.
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Janelia Research Campus @hhmijanelia.bsky.social · 23/07/2025
🪰 A new ‘Eyemap’ developed by a team led by Arthur Zhao & @michaelreiser.bsky.social reveals how visual information detected by the fly’s eye shows up in neurons deep in the brain. Remarkably, the eye’s shape determines how flies see motion.👁️ 🔗 hhmi.news/4kSZjou
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