Reposted by Janelia Research CampusHHMI @hhmi-science.bsky.social · 24/12/2025Our kind of annual tradition: Glucose + Tollens’ reagent + festive swirling = a chemical reaction that creates a thin layer of silver, loads of seasonal cheer, & ornaments worthy of being passed down for ... well, a few weeks at least. Happy holidays to all those who celebrate! ✨ 083
Reposted by Janelia Research CampusHHMI @hhmi-science.bsky.social · 17/12/2025“I feel being part of their life, being part of their career, is just priceless.” — HHMI Investigator Xin Chen, '25 Summer Undergraduate Research Program mentor 🧪 Rising junior or senior? Applications close 11:59pm Dec. 22! Explore a career in biological or biomedical research: bit.ly/CechFellows 063
Reposted by Janelia Research CampusHHMI @hhmi-science.bsky.social · 16/12/2025(1/2): What if the bacteria living in our digestive tracts could produce compounds that help us live longer? The Wang (Meng) Lab at HHMI's Janelia Research Campus has found a way to get gut microbes to produce metabolites that promote longevity in animals: hhmi.news/48QyPAm. 2202
Janelia Research Campus @hhmijanelia.bsky.social · 15/12/2025Apply by Feb. 3 to become a Janelia Group Leader! Group Leaders drive breakthroughs & experimental approaches in imaging, molecular engineering, protein chemistry, mass spectrometry, & methods that don't yet exist. Learn more: janelia.org/groupleader 🧪 01821
Reposted by Janelia Research CampusHHMI @hhmi-science.bsky.social · 05/12/2025(1/2): Using cryo-electron tomography and an instrument like this one, HHMI Investigator Michael Rosen & team (not pictured) have captured the most detailed images to date of the molecules inside chromatin condensates. hhmi.news/4iFBIrV 1144
Reposted by Janelia Research CampusHHMI @hhmi-science.bsky.social · 18/11/2025Calling all rising juniors & seniors: Interested in biological or biomedical research? Applications for our ’26 Summer Undergraduate Research Experience Program are now open! Nine weeks, hands-on research, & mentorship from some of the nation’s top scientists — learn more: bit.ly/CechFellowsbit.lySummer Undergraduate Research Experience | HHMIThe Cech Fellows Program is a paid, nine-week summer research experience empowering the next generation of scientific leaders. 07089
Janelia Research Campus @hhmijanelia.bsky.social · 03/11/2025ICYMI: A team of researchers unveiled the complete connectome of an entire male fruit fly central nervous system, encompassing the central brain, optic lobes, and ventral nerve cord. hhmi.news/4o3EJnk hhmi.newsResearchers reveal connectome of the male fruit fly central nervous systemA team of researchers at HHMI's Janelia Research Campus has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of... 0204
Reposted by Janelia Research CampusLuke Lavis @rhodamine110.bsky.social · 27/10/2025A new, nerdy paper. We figured out (some) of the rules underlying cell-permeability of probes and designed ligands that light up, grab, and move proteins around. Awesome @hhmijanelia.bsky.social x @uwmadison.bsky.social x @stjuderesearch.bsky.social collaboration! www.pnas.org/doi/10.1073/...pnas.orgPNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans... 08730
Janelia Research Campus @hhmijanelia.bsky.social · 23/10/2025Join the team at Janelia to use #theory, computation, and modeling to tackle bold questions in #biology. Collaborate across scientific disciplines to drive discovery. Apply by Nov. 3 @ janelia.link/theoryfellowprogram #computationalbiology #sciencecareers 0108
Reposted by Janelia Research CampusCatherine (Katie) Schretter @ceschretter.bsky.social · 23/10/2025Excited to announce our new pre-print (www.biorxiv.org/cgi/content/...)! This collaborative work (co-led by Adriane Otopalik and Gerry Rubin) examines how neuronal circuits regulate social behaviors, like courtship🫶 and aggression🥊, across sexes. #neuroscience #Drosophila #WomenInSTEM 🧪1/ 35432
Janelia Research Campus @hhmijanelia.bsky.social · 21/10/2025🦠 New research provides a mechanism for understanding how environmental changes to somatic cells are passed through the germline, helping scientists better understand transgenerational effects, like the malnutrition of a parent affecting its offspring. hhmi.news/4mCD3QO 031
Reposted by Janelia Research CampusChampalimaud Research @champalimaudr.bsky.social · 17/10/2025🪰 Srinivas Turaga @hhmijanelia.bsky.social opened #CRSy25 Day 3’s afternoon session with “Simulating the brain and body of the fruit fly” From detailed connectomes to full-body physics, they model how neural circuits generate flight & walking - bridging the gap between brain structure and behaviour. 181
Janelia Research Campus @hhmijanelia.bsky.social · 16/10/2025🌟 Apply to lead a lab at Janelia 🌟 We’re #hiring Group Leaders in our Computation & Theory research area. 🔹 5-year renewable appointment 🔹 Internal funding + generous resources 🔹 Collaboration across disciplines 📅 Apply by Nov. 4 👉 janelia.link/groupleader 084
Janelia Research Campus @hhmijanelia.bsky.social · 15/10/2025🎉 Congrats to Research Scientist Igor Siwanowicz: 5th & 8th place in the 2025 Nikon Small World Photomicrography Competition for his images of spores of a small tropical fern & mallow pollen germinating on stigma while being parasitized by a filamentous fungus. hhmi.news/491e0Uf 0142
Reposted by Janelia Research CampusChampalimaud Research @champalimaudr.bsky.social · 15/10/2025Opening talk: 🧠🐟 How does the whole brain coordinate learning, memory & movement? @mishaahrens.bsky.social @hhmijanelia.bsky.social unveils whole-brain imaging in zebrafish exploring how neural & body dynamics shape behaviour and adaptation. 131
Janelia Research Campus @hhmijanelia.bsky.social · 14/10/2025🧞Like its namesake, Janelia’s GENIE Project Team makes wishes come true. Luckily for biologists, this genie doesn’t grant just 3 requests. 🧪Learn about how GENIE has accelerated the development of best-in-class sensors for measuring neuronal activity. hhmi.news/4gFqwKX hhmi.newsUnleashing the GENIE: Janelia's Project Team develops state-of-the-art sensors for biological researchFor more than a decade, the GENIE Project Team at HHMI's Janelia Research Campus has collaborated with the research campus's tool developers and tool users to take innovative biological sensors from novel prototypes to widely used laboratory staples--a ... 061
Janelia Research Campus @hhmijanelia.bsky.social · 13/10/2025🧠 A new wiring diagram of the 166,000+ neurons in the brain & nerve cord of a male fruit fly is a key tool in uncovering how the brain enables complex behavior—information that could ultimately help scientists better understand what causes different diseases ➡️ hhmi.news/4o3EJnk 0134
Reposted by Janelia Research CampusRachel Lee, PhD @scientistrachel.bsky.social · 12/10/2025Today marks 4 years of enjoying the beautiful @hhmijanelia.bsky.social campus 🌳 091
Janelia Research Campus @hhmijanelia.bsky.social · 09/10/2025📢Apply by Dec. 3 for our joint graduate programs with the Johns Hopkins University School of Medicine in neuroscience & cross-disciplinary biology. 🧠Develop interdisciplinary research projects 🌍Join a collaborative environment 🔬Leverage shared resources & support teams ➡️ janelia.org/graduate 010
Janelia Research Campus @hhmijanelia.bsky.social · 07/10/2025🔊 Listen to Senior Group Leader Hari Shroff discuss microscopy, biology and his path through science in the latest episode of Ashoka University's The Science of It podcast: www.youtube.com/watch?v=dyoP5HwAFAc… youtube.comThe Science of Microscopy | Innovator Hari Shroff | The Science of It Ep. 4Microscopist Hari Shroff takes us deeper into the world of nature's tiniest beings in the latest episode of Ashoka University's #TheScienceofIt podcast. What made a computer scientist and physicist turn to building microscopes to explore the beauty of ... 091
Reposted by Janelia Research CampusLaura Grima @lauragrima.bsky.social · 07/10/2025Pleased to have this review out in @cp-trendsneuro.bsky.social. In it we discuss various aspects of the intersection between foraging behaviors and neuroscience, and offer some future directions: www.sciencedirect.com/science/arti...sciencedirect.comForaging as an ethological framework for neuroscienceThe study of foraging is central to a renewed interest in naturalistic behavior in neuroscience. Applying a foraging framework grounded in behavioral … 35518
Janelia Research Campus @hhmijanelia.bsky.social · 06/10/2025🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them. 🔗 hhmi.news/4o3EJnk 14620
Janelia Research Campus @hhmijanelia.bsky.social · 04/10/2025Become a Theory Fellow @hhmijanelia.bsky.social 🧪 Work alongside experimentalists to test and refine theories 🎯 Receive mentorship from leading computational scientists 🔁 Contribute to Janelia’s cross-disciplinary research environment Apply by Nov. 3 @ janelia.link/theoryfellowprogram 042
Janelia Research Campus @hhmijanelia.bsky.social · 01/10/2025🥼 New research from the Wang Lab reveals a novel connection between lysosomes & the epigenome and provides new insights into how lysosomes regulate longevity over generations & drive the histone-based transfer of epigenetic information between cells. 🔗 hhmi.news/4mCD3QO 040
Reposted by Janelia Research CampusAmerican Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 27/09/2025Plenary speaker spotlight ✨ Meng Wang (@bcmhouston.bsky.social / @hhmi.org) at #ASBMB26: “Racing the clock: Molecular mechanisms of aging.” ➡️Dive into the biochemical basis of aging, from metabolism to the genome: ow.ly/68i150X37Pm. #MakeItPossibble #AgingResearch #FutureOfScience 041
Janelia Research Campus @hhmijanelia.bsky.social · 26/09/2025✨ ICYMI: Researchers detail how neurotransmitter receptors in the fly brain change during development ➡️ hhmi.news/4mFMhMYhhmi.newsResearchers detail how neurotransmitter receptors in the fly brain change during developmentNew proteomics research is enabling scientists to decipher how neurotransmitter receptors behave and change as an organism develops. The new work could help scientists better understand the formation and function of synapses--the junctions where communi... 060
Janelia Research Campus @hhmijanelia.bsky.social · 25/09/2025🪱New research from the Wang Lab shows how changes in a worm’s lysosomes promoting longevity are transferred to its offspring through the epigenome, revealing how epigenetic modifications that help organisms cope with environmental stress can be inherited. 🔗 www.janelia.org/news/leaving...janelia.orgLeaving a mark: New research shows how longevity is inherited across generationsNew research from the Wang Lab reveals a novel connection between lysosomes & the epigenome and provides new insights into how lysosomes regulate longevity over generations & drive the histone-based t... 1125
Janelia Research Campus @hhmijanelia.bsky.social · 24/09/2025🥼 Working with tool developers & support teams, Janelia’s GENIE Project Team recently created next generation sensors for detecting the neurotransmitters glutamate & GABA and adapted a new tool aimed at controlling & studying specific neural circuits in flies. 🔗 hhmi.news/4gFqwKX 030
Janelia Research Campus @hhmijanelia.bsky.social · 19/09/2025📢 Applications are open for the 4th installment of our ChemTools conference. We'll explore: 🧪 Platforms & tools for analyzing cell/tissue networks ⚡ Methods to perturb biological networks 🔍 Applications that yield new insights 🛏️ Lodging + meals covered ➡️ Apply by Dec 5: janelia.news/CHM26 073
Reposted by Janelia Research CampusStephan Saalfeld @herrsaalfeld.bsky.social · 18/09/2025We are looking for an #AIEngineer to help build protein language models that capture evolutionary constraints with @matsen.bsky.social and @jbloomlab.bsky.social at #AI@HHMI @hhmijanelia.bsky.social hhmi.wd1.myworkdayjobs.com/en-US/Extern...hhmi.wd1.myworkdayjobs.comAI Engineer - Evolutionary Protein Language ModelsPrimary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. Intro: AI@HHMI: HHMI is investing $500 million over the next 10 years ... 0116
Janelia Research Campus @hhmijanelia.bsky.social · 18/09/2025🌟 Launch your own lab at Janelia 🌟 Advance our understanding of biology through theory, computational modeling & machine learning. 🔹 No teaching requirements 🔹 100% internally funded 🔹 Collaborate with expert support teams 📅 Apply by Nov. 4 👉 janelia.link/groupleader 0710
Janelia Research Campus @hhmijanelia.bsky.social · 16/09/2025🧪For more than a decade, the GENIE Project Team has collaborated with tool developers & users to take innovative biological sensors from novel prototypes to widely used laboratory staples. Now, @janeliagenie.bsky.social is unveiling their latest collaborations. www.janelia.org/news/unleash...janelia.orgUnleashing the GENIE: Janelia’s Project Team develops state-of-the-art sensors for biological researchFor more than a decade, the GENIE Project Team at HHMI’s Janelia Research Campus has collaborated with the research campus’s tool developers and tool users to take innovative biological sensors from n... 083
Janelia Research Campus @hhmijanelia.bsky.social · 12/09/2025📢 Applications are open! Join us in May to explore computational simulation of biomechanical body models, bridging #neuroethology, #ML, physics simulation & computer vision. 🧠🤖 👁 🛏️ Lodging, meals & registration covered ➡️ Apply by Nov. 21 @ janelia.news/SIB26 071
Janelia Research Campus @hhmijanelia.bsky.social · 09/09/2025Become a Theory Fellow at Janelia. 🔍 Use computation & theory to tackle biological problems. 🖥️ Leverage state-of-the-art computational infrastructure 🤝 Collaborate across scientific disciplines Apply by Nov. 3 @ janelia.link/theoryfellowprogram 01911
Reposted by Janelia Research CampusMisha Ahrens @mishaahrens.bsky.social · 08/09/2025Preprint - Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo. www.biorxiv.org/content/10.1... 319370
Janelia Research Campus @hhmijanelia.bsky.social · 05/09/2025📢 Conduct your PhD thesis research at Janelia. 🎓 Apply by Dec 3 for our joint graduate programs with Johns Hopkins School of Medicine in neuroscience & cross-disciplinary biology. 🌐 Collaborate across disciplines 🛠️ Work with tool builders 🤝 Train in a supportive environment ➡️ janelia.org/graduate 0104
Janelia Research Campus @hhmijanelia.bsky.social · 03/09/2025Research detailing how nicotinic acetylcholine receptors—the main type of neurotransmitter receptor in the fly brain—change during development lays the groundwork for understanding the molecular composition, regulation & adaptability of these synapses➡️ hhmi.news/4mFMhMY 073
Reposted by Janelia Research CampusHHMI @hhmi-science.bsky.social · 28/08/2025🎉Congratulations to David Baker, winner of the @royalsociety.org's Croonian Medal and Lecture for pioneering the design of completely new proteins and playing key roles in the development of protein structure prediction and protein engineering tools. 🔗 royalsociety.org/medals-and-p... 0133
Janelia Research Campus @hhmijanelia.bsky.social · 27/08/2025🧪 New proteomics research is enabling scientists to decipher how neurotransmitter receptors behave & change as an organism develops, information that could help scientists better understand the formation & function of synapses.➡️ hhmi.news/4mFMhMY janelia.orgResearchers detail how neurotransmitter receptors in the fly brain change during developmentNew proteomics research is enabling scientists to decipher how neurotransmitter receptors behave and change as an organism develops. The new work could help scientists better understand the formation and function of synapses--the junctions where communi... 093
Janelia Research Campus @hhmijanelia.bsky.social · 26/08/2025📢We're #hiring Group Leaders! Apply to lead a lab at Janelia & advance biology using theory, computational modeling & machine learning. 🔹5-year renewable appointment 🔹Pioneer new tools & approaches 🔹Collaborate across disciplines Apply by Nov. 4👉 janelia.link/groupleader 06365
Janelia Research Campus @hhmijanelia.bsky.social · 25/08/2025❄️Time-deterministic cryo-optical microscopy, developed by researchers at the University of Osaka, Janelia & collaborating institutions, rapidly freezes live cells under an optical microscope, capturing a snapshot of cellular activity in high resolution➡️ hhmi.news/421MTUL 0160
Reposted by Janelia Research CampusHHMI @hhmi-science.bsky.social · 22/08/2025Please join us in congratulating HHMI Investigators Jennifer Doudna (@jenniferdoudna.bsky.social) and David R. Liu, recipients of national awards from the American Chemical Society (@acs.org) for 2026. 🔗 cen.acs.org/people/award... 1232
Reposted by Janelia Research CampusAndy Moore @aaandmoore.bsky.social · 18/08/2025This is an airyscan confocal movie of mitochondria (white) moving around in a mouse astrocyte. Actin filaments are in orange and microtubules are in blue. 1533668
Janelia Research Campus @hhmijanelia.bsky.social · 20/08/2025🖥️ PEELing, a user-friendly platform developed by the Li Lab & Janelia’s Scientific Computing Software support team, allows researchers to analyze spatial proteomics data with the click of a mouse ➡️ hhmi.news/47FETwh academic.oup.comPEELing: an integrated and user-centric platform for spatially resolved proteomics data analysisAbstractSummary. Molecular compartmentalization is vital for cellular physiology. Spatially resolved proteomics allows biologists to survey protein composi 100
Janelia Research Campus @hhmijanelia.bsky.social · 19/08/2025📷Happy #WorldPhotographyDay! 🎉To celebrate, we’re sharing a few macrophotography images taken by Janelia Research Specialist Igor Siwanowicz. 🔬Siwanowicz's images have placed 20+ times in the Nikon Small World & Olympus BioScapes competitions & were featured on US Postal Service stamps in 2023. 0299
Janelia Research Campus @hhmijanelia.bsky.social · 05/08/2025✨ We’re #hiring Theory Fellows!✨ Janelia is recruiting early-career scientists to join our collaborative research environment and use #computation & #theory to tackle bold questions in #biology. 🔗 Apply by Nov. 3 👉 janelia.link/theoryfellow... @hhmi.org 11410
Janelia Research Campus @hhmijanelia.bsky.social · 01/08/2025🧠 Scientists have struggled to build computational models simple enough to understand what individual neurons in the primary visual cortex are doing. 🖥️ Now, Janelia researchers are helping to solve that problem with a new class of simplified “minimodels.”janelia.orgNew computational model could help shed light on how we seeResearchers in the Stringer and Pachitariu labs at Janelia set out to create a simpler model to explain what’s going on in the primary visual cortex – the first stop in the brain for visual data. 051
Reposted by Janelia Research CampusJanelia GENIE @janeliagenie.bsky.social · 29/07/2025🧠🪰 New from GENIE @HHMIJanelia: far-red #RubyACRs from the Spudich Lab enable robust optogenetic inhibition in freely behaving #Drosophila — validated with ephys, imaging & behavior. 📄 Paper bit.ly/3H7S7af 🪰 Get flies bit.ly/41iVNwK med.uth.edu/bmb/spudich/ #OptoInhibition #FlyNeuro #FlyOptogenetics 073
Janelia Research Campus @hhmijanelia.bsky.social · 23/07/2025🪰 A new ‘Eyemap’ developed by a team led by Arthur Zhao & @michaelreiser.bsky.social reveals how visual information detected by the fly’s eye shows up in neurons deep in the brain. Remarkably, the eye’s shape determines how flies see motion.👁️ 🔗 hhmi.news/4kSZjou 410022