How is proliferation modulated in regeneration for tissues to reach their right size? We found that, in zebrafish scales, proliferation is shut down by a moving front of osteoblast maturation. The front's dynamics scale with tissue size, ensuring proper osteoblast amplification. tinyurl.com/5e45twx3
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A moving front of osteoblast maturation scales regenerating zebrafish bone
Successful regeneration recovers lost tissues to their original form. Here, we investigate how proliferation of bone-forming osteoblasts is timely regulated to control tissue size during zebrafish sca...