Department of Developmental NeurobiologyCenter of Excellence for Structural Cell Biology and Neuronal Cell Biology DivisionSt. Jude Children’s Research HospitalThe Center of Excellence for...

Tunneling nanotube-like (TNT) connections allow mitochondrial exchange between tumor cells and its tumor microenvironment. Here, the authors show that TNT connections mediate bidirectional mitochondri...

The Munson Lab researches the mechanistic basis for the regulation of spatial and temporal specificity in membrane trafficking in the Biochemistry & Molecular Biotechnology Department at UMass Chan Me...

A subset of cardiac neurons keep the heart from malfunctioning in stressed mice.

Fluorescent proteins and small-molecule dyes offer complementary advantages for biological imaging: proteins are amenable to genetic tagging, whereas dyes provide superior brightness and photostabilit...

The Odyssey — Hinds, Gareth, 1971- — Retells, in graphic novel format, Homer's epic tale of Odysseus, the ancient Greek hero who encounters witches and other obstacles on his journey home after fighti...

Jha et al. show that the transmembrane protein CD44 restricts EGFR mobility to maintain an EGFR–PI3K–Rac gradient during bleb-based cell migration.

Some microbe species have evolved to stab, bomb, cannibalize, or poison each other. Can we harness their weapons for good?

Nature Reviews Molecular Cell Biology, Published online: 02 June 2026; doi:10.1038/s41580-026-00964-2Caveolae are membrane invaginations that facilitate cell signalling and act as membrane reservoirs. This Review discusses recent insights into caveolae assembly and disassembly, their roles in mechanotransduction and how impaired caveolae mechanics contribute to human disease.

Sympathetic innervation requires transport of TrkA from the soma surface to the axon.

Hurwitz et al. leverage a novel FRET-based approach to quantify conformational dynamics of Mfn1, a member of the dynamin superfamily that mediates mitochon

PDB-101: Training, Outreach, and Education portal of RCSB PDB

This Perspective discusses the mechanisms underlying both the formation and scission of caveolae, with a focus on highlighting the role of specific lipids in regulating and coupling these processes.

A series of spontaneously blinking dyes in the far-red range facilitate single-molecule localization microscopy. These dyes vary in their blinking properties and can be matched to the applications and...