A scrappy science project led to a significant discovery: two new species of a rare organism that could elucidate a fundamental transition in the history of life on our planet.

Transposable elements (TEs) are key contributors to genome evolution, yet their macroevolutionary roles in adaptive radiations remain poorly understood, as high-quality genomic resources at sufficient...

The Earlham Institute has been awarded funding by the Gordon and Betty Moore Foundation to develop Protist Omics at Scale, a three-year international methods-development programme run in partnership with the Scottish Association for Marine Science, home of the Culture Collection of Algae and Protozoa, and Aalborg University.

Animal cells extensively remodel their cytoskeleton during differentiation and can notably switch between two major motility modes: flagellum-based swimming and actin-based crawling. We previously sho...

Microtubules are essential components of the cytoskeleton, yet important links between their molecular properties and organismal functions remain unresolved. In this Roadmap, Janke et al. discuss key ...

Abstract. Warnowiid dinoflagellates are known for possessing two of the most complex structures known in single cells: multi-projectile nematocysts and the

Abstract. Chloroplast-stealing (a.k.a., “kleptoplastidic”) plankton transiently obtain and integrate prey metabolic machinery into their own cells. To do s

Asgard archaeal mini microtubules suggest an archaeal origin of eukaryotic microtubules.

Molecules in the cytoplasm of an animal cell move by diffusion, motor activity, and/or fluid flow. A recent study demonstrates how directed, but often subtle, cytoplasmic drift currents carry cytoskel...

The MBL's Semester in Biological Discovery (SBD) is a 12-week program that provides an immersive research experience in discovery-driven biological sciences modeled on the MBL's world-renowned Advanced Research Training Courses. The SBD program is also ...

Jha et al. show that the transmembrane protein CD44 restricts EGFR mobility to maintain an EGFR–PI3K–Rac gradient during bleb-based cell migration.

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Some microbe species have evolved to stab, bomb, cannibalize, or poison each other. Can we harness their weapons for good?

The molecular mechanisms that produce cell structure are poorly understood. The giant ciliate Stentor coeruleus is a unicellular model organism who...

Experiments using the comb jelly Mnemiopsis leidyi and the sea anemone Nematostella vectensis reveal that the emergence of a core signalling pathway may have been a key innovation enabling the transit...

The chrompodellids are a collection of photosynthetic “chromerids” and heterotrophic “colpodellids,” which are together the sister lineage to the apic…

A previous study in PLOS Biology developed IntAct, a tool to study isoform-specific actin localization, dynamics and molecular interactions across species. In this Update Article, IntAct is coupled wi...