iiinova — where your digital self keeps evolving

Reposted by Victor Puelles

Wolfgang Huber @wkhuber.bsky.social · 28/07/2026

Spatialproteomics: an interoperable toolbox for analyzing highly multiplexed fluorescence image data By @matthiasmeybe.bsky.social et al. Great collaboration with the group of Sascha Dietrich and Peter-Martin Bruch. doi.org/10.1038/s415...

multiplexed immunohistochemistry of lymphoma biopsies, arranged as a hexagon

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FocalPlane @focalplane.bsky.social · 29/05/2026

We are excited to announce another new webinar series, this time on cell migration, hosted by @pjsaez.bsky.social & @valeriaventurini.bsky.social. In our 1st webinar, we’ll hear talks from @juanmagararc.bsky.social, @kyohalie.bsky.social & @djcohen.bsky.social. 🗓️11 June, 15:00 BST

focalplane.biologists.com

New webinar series on cell migration - FocalPlane

New webinar series on cell migration - News

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Science Magazine @science.org · 28/05/2026

Researchers have identified superparamagnetic macrophages in the livers of rock pigeons to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation. scim.ag/4nTQ3nq

How animals sense Earth’s magnetic field is one of biology’s enduring mysteries. Researchers have now identified superparamagnetic macrophages in the livers of rock pigeons (Columba livia) to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation.

Photo: Andreas Teichmann/laif/Redux

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JCI insight @insight.jci.org · 25/04/2026

BKV is a common virus that can cause kidney transplant complications doi.org/10.1172/jci.... Abhijit S. Naik & team @umich.edu analyze biopsies from transplant kidneys, describing epithelial injury pathways & cell type differences between peaking & resolving infection stages.

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Estibaliz Gómez de Mariscal, PhD @gomez-mariscal.bsky.social · 11/03/2026

Big news🥂I'll start my research group at NIMSB!🔥🎉Hard to describe how HAPPY+EXCITED I am about bringing new #AI #imagedriven biomedical research + growing together🌱I'm grateful to my supervisors,colleagues,collabs+mentors who inspired+encouraged me throughout 🤍

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Juan Carlos Q Vélez, MD @juancarlosqvelez.bsky.social · 10/03/2026

Very excited for this, come down to beautiful Tarapoto in Peru 🇵🇪 to enjoy nature and a few acid-base & electrolyte lectures 💪 9/3-4, 2026.

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Ardem Patapoutian @ardemp.bskyverified.social · 04/03/2026

New paper from the lab led by @ericmulhall.bsky.social addresses how PIEZO1 and PIEZO2 are tuned to different types mechanical forces. From nanometer-scale super-resolution microscopy to in vivo experiments, links single-molecule observations to physiological function. www.nature.com/articles/s41...

nature.com

The molecular basis of force selectivity by PIEZO2

Nature - PIEZO2 is intrinsically more rigid than PIEZO1, and disparate mechanical stimuli paradoxically evoke opposite conformational and gating responses in each channel.

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Julio Saez-Rodriguez @juliosaezrod.bsky.social · 16/02/2026

Do you want to pursue your ideas in computational biology independently, running your group in @embl.org‘s uniquely collaborative environment, beside world’s most comprehensive biomolecular data resources @ebi.embl.org in Genome Campus next to @sangerinstitute.bsky.social? Apply to join us & share 🙏

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Juan Carlos Q Vélez, MD @juancarlosqvelez.bsky.social · 31/01/2026

Time to start booking your renal conferences for 2026. Highly recommend KidneyCon @kidneycon.bsky.social kidneycon.org/ibili Hot topics, stellar speaker line-up, one-of-a-kind hands-on workshops, and fantastic camaraderie an networking, simply a great nephrology conference. Register now!

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BioContextAI @biocontext.ai · 20/01/2026

🤖🧬 New biomedical MCP server added to the registry: Open Targets Platform MCP Check it out at biocontext.ai/registry/opentargets/…

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Pablo J. Sáez @pjsaez.bsky.social · 09/01/2026

#FluorescenceFriday Proud of our the last paper @cellcommlab.bsky.social & 1st one of @jboixcampos.bsky.social We continue to study #CellMigration & how cells decide where to go: ↖️↗️⬇️? (movie of the actin #cytoskeleton) Full www.science.org/doi/10.1126/... @focalplane.bsky.social @science.org 🧪🔬

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Eduardo Villablanca @ejvillablanca.bsky.social · 09/01/2026

Our KAW research grant focuses on uncovering novel drivers of mucosal healing by leveraging unique IBD cohorts and novel technologies to map cell–microbiota interactions, complemented by advanced non-animal models like human organoids Check the note 👇🏼 kaw.wallenberg.org/en/research/... #Hashtag

kaw.wallenberg.org

Promoting healing to cure intestinal autoimmunity | Knut and Alice Wallenberg Foundation

Immunosuppressive drugs are currently the main therapeutic option for treating inflammatory bowel disease (IBD). However, fewer than half of patients achieve sustained benefit, and these treatments ca...

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Ricardo Henriques @henriqueslab.bsky.social · 15/12/2025

🚨🔬🤖🚀 #PhotoFiTT is out! With @guijacquemet.bsky.social's & @microbematos.bsky.social's labs, we launched a new phototoxicity measurement for live microscopy using cell clocks⏱️. By rockstars @mariodelr.bsky.social @gomez-mariscal.bsky.social et al! AI-powered + label-free doi.org/10.1038/s414...

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Mario Del Rosario @mariodelr.bsky.social · 15/12/2025

It’s FINALLY out! 🎉🚀 We have been working on PhotoFiTT for a long time, and it’s now published, introducing a quantitative framework to measure phototoxicity and optimise live-cell microscopy experiments. So excited to finally share the last version! 🔬✨ #PhotoFiTT doi.org/10.1038/s414...

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Estibaliz Gómez de Mariscal, PhD @gomez-mariscal.bsky.social · 15/12/2025

🚨Amazing news for a cloudy Monday!🌩️😎 I'm extremely happy to share that our last adventure is finally out!🚀🎉Phototoxicity fitness time trial (#PhotoFiTT) - a quantitative framework for assessing phototoxicity in live-cell microscopy experiments 🔬❤️‍🔥⚡️ doi.org/10.1038/s414...

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EMBL-EBI @ebi.embl.org · 02/12/2025

AI holds huge promise for life science research. But unreliable answers currently limit its impact. @juliosaezrod.bsky.social, Head of Research at EMBL-EBI, discusses how Model Context Protocol (MCP) servers are helping to change this. www.ebi.ac.uk/about/news/p... 🧬💻

ebi.ac.uk

Connecting AI to biology: Model Context Protocol

Julio Saez-Rodriguez discusses how MCP servers are helping AI connect to life science databases, making AI a more reproducible tool for research.

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Eduardo Villablanca @ejvillablanca.bsky.social · 29/11/2025

Doctoral (PhD) Position – Spatial Transcriptomics, Bioinformatics & Mucosal Immunology 📍 Karolinska Institutet, Sweden 🗓️ Deadline: Dec 10, 2025 kidoktorand.varbi.com/what:job/job... #SpatialTranscriptomics #Bioinformatics #MucosalImmunology #SingleCellOmics #IBDResearch #SystemsImmunology

lnkd.in

This link will take you to a page that’s not on LinkedIn

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Reposted by Victor Puelles

Thomas Worzfeld @worzfeld.bsky.social · 27/11/2025

Truly happy to host Victor Puelles in Marburg today, talking about complex tissue analysis across biological scales. Thrilling science and exciting discussions! @puellesv.bsky.social

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Rita Strack @ritastrack.bsky.social · 17/11/2025

Really excited for our November issue, and I feel like I'm starting to get into the groove of writing editorials for nBME (with the help of the team of course!). Please check it out!

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Reposted by Victor Puelles

Rita Strack @ritastrack.bsky.social · 13/11/2025

I won't talk about NMeth @natmethods.nature.com forever (probably), but I do want to brag a bit about the November focus issue on cell segmentation and tracking, which is many ways is my last hurrah (and final editorial) for the journal. I am so proud of these papers!! www.nature.com/nmeth/volume...

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Nature Biotechnology @natbiotech.nature.com · 12/11/2025

BioContextAI is an open-source initiative for creating agentic biomedical research assistants from standardized components go.nature.com/3JmqKux rdcu.be/ePz3v

go.nature.com

BioContextAI is a community hub for agentic biomedical systems - Nature Biotechnology

Nature Biotechnology - BioContextAI is a community hub for agentic biomedical systems

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ASN Publications @asnpublications.bsky.social · 06/11/2025

The Eknoyan Lectureship at #KidneyWk will cover KDIGO Guidelines for CKD on Saturday. Read about the speaker in #ASNKidneyNews kidney.pub/KN1710-55

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ASN Publications @asnpublications.bsky.social · 06/11/2025

At #KidneyWk? Celebrate and listen to the ASN-American Heart Association Donald W. Seldin Young Investigator Award winner, Rafael Kramann, who will speak on “Cell by Cell, Space by Space: Unraveling Fibrosis in the Kidney and Heart” on Friday, November 7. kidney.pub/KN1710-35 #ASNKidneyNews

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BioContextAI @biocontext.ai · 26/10/2025

🤖🧬 New biomedical MCP server added to the registry: Skill-To-MCP Server Check it out at biocontext.ai/registry/biocontext-a…

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BrownLab @Mt.Sinai @brownlab1.bsky.social · 17/10/2025

Our new review in @natbiomedeng.nature.com is out! RNA-loaded lipid nanoparticles (LNPs) have huge potential—but their strong liver and immune cell uptake has mostly confined them to vaccines and liver therapies. We explore how to move beyond those limits. free to read 🔗 rdcu.be/eLxGs

rdcu.be

Targeting and tracking mRNA lipid nanoparticles at the particle, transcript and protein level

Nature Biomedical Engineering - This Review explores strategies for targeting and tracking RNA-LNP drugs, monitoring their in vivo behaviour, enhancing tissue-specific delivery, and using synthetic...

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Brandy A Freitas @brandy-syglass.bsky.social · 23/10/2025

The #mesoSPIM community just celebrated 10 years of open-source light-sheet microscopy in Zürich! For #3DThursday, we're honoring Martina Schaettin & Fabian Voigt’s iconic 3D chick embryo dataset — a luminous benchmark for open science and shared discovery. #Microscopy #Lightsheet #syGlass

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Ricardo Henriques @henriqueslab.bsky.social · 22/10/2025

🦠🔬🤖🧑‍💻 #mAIcrobe is out! With @pinholab.bsky.social's lab, we launched an open-source framework for high-throughput bacterial image analysis. By rockstars A. Brito & B. Saraiva et al, making #DeepLearning for phenotyping accessible! Easy to use, plus model training 📜 www.biorxiv.org/content/10.1...

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mesoSPIM: Clear Images. Big samples. Open source. @mesospim.bsky.social · 10/10/2025

Job opportunity at the University of Zurich! 📢 We are looking for a 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐢𝐚𝐧 / 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐀𝐬𝐬𝐢𝐬𝐭𝐚𝐧𝐭 (𝟒𝟎%) to join our Microscopy Innovation Platform (MIP), an open-source initiative focused on advancing and making light-sheet and multiphoton microscopy accessible to researchers. 1/3

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Humboldt-Stiftung @humboldt-foundation.de · 08/10/2025

✨🥳🎉 Heartfelt congratulations to Humboldtians Susumu Kitagawa and Omar M. Yaghi on winning the #NobelPrize in Chemistry 2025 which they share with Richard Robson for the development of "metal-organic frameworks"! We are truly honoured to have supported a step in their exceptional journey! 💚

Three portraits of men – the 2025 Nobel Prize winners in Chemistry

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Humboldt-Stiftung @humboldt-foundation.de · 07/10/2025

✨✨✨ Huge congratulations to the winners of the #NobelPrize in Physics: John Clarke, Michel H. Devoret and John M. Martinis. Clarke and Martinis are both members of the Humboldt Network – as hosts for Feodor Lynen Research Fellows! 💚 Picture: Ill. Niklas Elmehed © Nobel Prize Outreach

Three drawn portraits of men – the Nobel Prize winners in physics in 2025

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Fabian Theis @fabiantheis.bsky.social · 28/09/2025

🚀 Excited to share scPortrait! Led by Sophia Mädler & Niklas Schmacke w/ the Mann lab — a new @scverse tool for standardized single-cell image data. Enables ML-ready extraction, >1B cell processing, cross-omics, & cancer macrophage insights. 🔗 www.biorxiv.org/content/10.1...

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Rachel Lennon @rachellennon.bsky.social · 19/09/2025

Check out our latest review on Basement Membranes! Including scaled representation of protein & glycan components 😊 @mcrcellmatrix.bsky.social

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Saez-Rodriguez Group @saezlab.bsky.social · 17/09/2025

🥁 Check out our new preprint on OmniPath, the prior knowledge resource for #SystemsBiology, and its brand-new OmniPath Explorer web app! 🥳 📖 Preprint: www.biorxiv.org/content/10.1... 🔍 Explorer: explore.omnipathdb.org OmniPath integrates 160+ resources for multi-omics analysis & modeling. 🧶⬇️

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Pablo J. Sáez @pjsaez.bsky.social · 01/09/2025

Today 20 years after I started working in a scientific lab while still in 🇨🇱, my lab, the @cellcommlab.bsky.social has its 5th labversary. What a ride ! I'm thankful for the support of my family, friends, & so many great collabs & colleagues. Fig legend 👇🏽 + pending longer thread #PIlife #Science

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voigtvision.bsky.social @voigtvision.bsky.social · 21/08/2025

Definitely the most unexpected @mesospim.bsky.social #lightsheet #microscopy application of the past years: Hunting dark matter with a lightsheet microscope! #astronomy 🔭🔬https://arxiv.org/abs/2503.20732

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Gautam Dey @gautamdey.bsky.social · 07/08/2025

Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you! embl.wd103.myworkdayjobs.com/en-US/EMBL/j... With @dudinlab.bsky.social @embl.org @biology-unige.bsky.social @moorefound.bsky.social

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Saez-Rodriguez Group @saezlab.bsky.social · 31/07/2025

Glad to contribute to this collaborative community platform. A case study shows MCP servers working together - combining BioContextAI Knowledgebase with our omnipath omnipathdb.org MCP (work in progress) to showcase interoperability. Looking forward to see how the ecosystem evolves!

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Malte Kuehl @maltekuehl.com · 29/07/2025

Preprint alert 🚨 Do you use chatbots in your work or even build MCP servers and agentic systems yourself? Or would you like to find a way to use biomedical tools using natural language? Then check out biocontext.ai, now out on bioRxiv: www.biorxiv.org/content/10.1...

Diagram showing MCP-enabled research architecture. Part A illustrates the flow between MCP servers (including BioContextAI Knowledgebase MCP and Community-developed MCP servers), Agentic systems connected via Model Context Protocol, and researchers asking research questions. MCP servers connect to knowledgebases and specialized software. Part B details the BioContextAI project components, divided into Registry (Schema.org ontology, Web interface, Open source licensing, MCP-enabled chatbot, Continuous integration) and Community (Documentation, Community forums, MCP server reviews, Shareable collections, Interoperability with tools like BioChatter).

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Malte Kuehl @maltekuehl.com · 18/07/2025

🚨Scaling multiplexed imaging 📈 We are excited to share Pathology-oriented multiPlexing (PathoPlex). Now out in @nature.com: www.nature.com/articles/s41... 🧵Walk-through thread below ⬇️

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Pablo J. Sáez @pjsaez.bsky.social · 18/07/2025

#HotFromThePress !! What if instead of analyzing 4-6 pathology markers you could check >100 in the *same* sample? @maltekuehl.com & co @puellesv.bsky.social lab introduce #PathoPlex, method that could even predict disease Full www.nature.com/articles/s41... @focalplane.bsky.social @nature.com 🧪🔬

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Saez-Rodriguez Group @saezlab.bsky.social · 16/07/2025

Four more days to apply to our postdoctoral position 👇

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