TGFβ is an important cytokine that controls cellular behavior and its activity is tightly regulated. Here, the authors determine the structure of the large latent TGFβ complex with LTBP1, to show how ...

This link will take you to a page that’s not on LinkedIn

Dr Kerrie Marie’s research group at the University of Manchester is looking for a Grade 5 Research Technician to join their team studying melanoma cell plasticity. This is an exciting opportunity to c...

Nature Communications - Collagen VI microfibril cryo-EM structure resolves a cysteine-rich coiled-coil important for heterotrimerization and microfibril assembly, reveals a hotspot of collagen VI...

This link will take you to a page that’s not on LinkedIn

YouTube video by Manchester Cell Matrix Centre

YouTube video by Manchester Cell Matrix Centre

YouTube video by Manchester Cell Matrix Centre

Collagen deposition in fibroblasts, the primary collagen-producing cells, is regulated by both macrophages and the circadian rhythm, although how these regulatory processes interact with one another i...

Apply for the Research Associate - Mechanisms Associated with Extracellular Matrix Assembly and Stability role on jobs.ac.uk, the top job board for academic positions in higher education. View details...

Summary: The recently discovered extracellular matrix protein SNED1 promotes the adhesion of breast cancer cells and neural crest cells via interaction with α5β1 and αvβ3 integrins, the first SNED1 re...

PhD Project - (BBSRC NWD) Developing biomaterials to engineer how cancer cells sense force to regulate gene expression at The University of Manchester, listed on FindAPhD.com

Secretion and fibrillogenesis of collagen-I are separately controlled molecular pathways in the fibroblast, where surprisingly endocytic recycling is required for fibril formation and is increased in ...