Genetic screens in immune cells enable the systematic interrogation of gene function at scale, uncovering key regulators of cell functions such as tumor cell killing and persistence. However, existing...

“We can no longer lend our credibility to an organization that has lost its integrity,” write four scientists and administrators who recently resigned from the NIH.

PhD admissions coaching and fellowship coaching for college through postdoc applicants. Strategy + writing feedback for SOP/personal/research statements, CV/resume, supplements, and interview prep. Su...

Proteasomal degradation of cellular proteins generate defence peptides constitutively and in response to bacterial infection. Such peptides might provide a source of natural antibiotics that...

TIRTL-seq is a high-throughput method for paired T cell receptor sequencing at the cohort scale.

Aging encompasses low-level inflammation and motor decline. Astrocytes are neuroregulatory glial cells that change in aging, particularly in the cerebellum, which is essential for movement coordinatio...

LJI scientists team up with Colorectal Cancer Alliance's Project Cure CRC to end this devastating cancer

Donor-supported internship program brings talented students to LJI labs

Discover Talk2Data – a BioTuring project offering tutorials, interactive tools, and curated content for biology learners and researchers.

This study reveals how cardiolipin governs mitochondrial morphology by modulating the activity of human OPA1 and how its replacement by monolyso-cardiolipin, as observed in Barth syndrome, impacts mitochondrial membrane-shaping mechanisms.

Cheung et al. describe efficient T cell control of nascent neoantigen+ and nearby neoantigen-negative sarcoma cells, underlying a ∼50% reduction in tumor penetrance. This otherwise imperceptible immun...

RAEFISH delivers whole-transcriptome (>20,000 genes) imaging at single-molecule resolution in cells and tissues and enables direct gRNA detection for high-content, image-based CRISPR screens.

The National Institutes of Health is on track to give away all of its grant money to labs, but research on cancer, aging and diabetes is still being left behind.

YouTube video by La Jolla Institute for Immunology

A geological, petrographic and geochemical survey of distinctive mudstone and conglomerate outcrops of the Bright Angel formation on Mars reveals textures, chemical and mineral characteristics, and or...

YouTube video by Forbes Breaking News

The ruling is a legal victory for Harvard but the White House says it will appeal the decision.

LJI scientists uncover a new avenue for stopping cancers, autoimmune diseases, and more.

YouTube video by La Jolla Institute for Immunology