iiinova — where your digital self keeps evolving

Brandy A Freitas @brandy-syglass.bsky.social · 01/10/2026

🔬 #3DThursday at #BINA2026! 3i shared a cochlea imaged on their AxL light-sheet microscope with a Hamamatsu camera. Downloading it apparently crashed the conference Wi-Fi ... sorry, guys, but I needed the data immediately! 😅 🎬 syGlass v2.7.1 @the.3i.social @hamamatsucorp.bsky.social

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New England Society for Microscopy @nesmicroscopy.bsky.social · 30/09/2026

🔬A slightly late #MicroscopyMonday, but we have a good excuse: we’re at BioImaging North America in Madison this week! #BINA2026 If you’re here, come find the NESM crowd and say hi! (Harry not pictured due to being incredibly delayed by the nor'easter ... 🌧️) #Microscopy #BioImaging #NESM

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Brandy A Freitas @brandy-syglass.bsky.social · 21/09/2026

That's me! I'll be there! Come to BINA! 🔬

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Brandy A Freitas @brandy-syglass.bsky.social · 17/09/2026

A special #3DThursday: cleared human embryos showing the developing cerebral vasculature in 3D. 🔬 @miltenyibiotec.bsky.social Blaze #LSFM + iDISCO+ 🥼 Shotar et al. 📝 Journal of Anatomy (2026) 🏛️ Institut de la Vision, Paris 🎬 #syGlass v2.2.1+ @alainchedotal.bsky.social @sorbonne-universite.fr

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New England Society for Microscopy @nesmicroscopy.bsky.social · 14/09/2026

So excited to announce our Fall Symposium for #MicroscopyMonday! Come and see us for two days of talks, workshops, and networking University of Connecticut this December. 🔬 Register now to get 10% off with code 2026EARLYBIRD: www.nesmicroscopy.org/2026-fall-sy... #NESM #Microscopy #SciComm

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Brandy A Freitas @brandy-syglass.bsky.social · 10/09/2026

#3DThursday! Widefield live imaging from a Duchenne model. Not my usual #syGlass data type, but here it works surprisingly well. In this video, I'm following muscle stem cells moving along an mdx fiber over time. 🔬 ZEISS Observer Z1 🥼 Liza Sarde et al. @sardeliza.bsky.social 🎬 syGlass, v2.7.1

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Brandy A Freitas @brandy-syglass.bsky.social · 08/09/2026

NYC friends! Come see syGlass (and me!) in action at NYU Langone. Open to anyone, I'll have the Spatial Reality Display and 6DOF stylus. Would love to meet people in person and check out your data! 🎤 Talk: 10 AM 🥽 Demos: 11 AM–4 PM 📍 Science Building 103, 435 E 30th St. #Bioimaging #Microscopy #VR

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Brandy A Freitas @brandy-syglass.bsky.social · 03/09/2026

🦎 Our unofficial conference mascot for #3DThursday: the veiled chameleon embryo! We’ve brought this dataset to nearly every major conference this year, and it’s always a crowd favorite. biologists.bsky.social, @devbiol.bsky.social 🔬: SCANCO μCT 40, #microCT 🥼: Raul E. Diaz 🎬: #syGlass, v2.7.1

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Brandy A Freitas @brandy-syglass.bsky.social · 27/08/2026

🕷️ A tick imaged with SEM-based #photogrammetry for #3DThursday! This type of #microscopy reveals the tiny structures researchers use to study tick ID, attachment, and feeding. 🔬: #SEM with a CSSG (compressed-sensing accessory) 🥼: Edward L. Principe 🏛️: PanoScientific 🎬: #syGlass, v2.7.1

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Brandy A Freitas @brandy-syglass.bsky.social · 20/08/2026

🪰 History for #3DThursday! In 2012, SiMView made it possible to image an entire developing Drosophila embryo in 3D every ~30 sec for hours — a huge step for 4D developmental imaging. 🔬: SiMView, digital-embryo.janelia.org 🥼: Tomer, Khairy, Amat, Keller 🎬: #syGlass v2.7.1 #LSFM #Microscopy

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Brandy A Freitas @brandy-syglass.bsky.social · 13/08/2026

🦋 #3DThursday: developing wing scales! In this clear region, scales form triangular and bristle shapes, like a tiny fluorescent sculpture garden. 🔬 @zeiss-microscopy.bsky.social LSM 880 confocal 🥼 @aaronpomerantz.bsky.social, Cao Lu Yan & Nipam Patel 🏛️ @mblscience.bsky.social 🎬 #syGlass v2.7.1

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Brandy A Freitas @brandy-syglass.bsky.social · 06/08/2026

SEM-based #photogrammetry for #3DThursday! We got this unique dataset on the floor of the M&M conference yesterday -- a new technique for me. 🔬: SEM with a CSSG (compressed-sensing accessory) 🥼: Edward L. Principe 🏛️: PanoScientific 🎬: #syGlass, v2.7.1 #MM2026 #SEM #Microscopy #MandM2026

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Brandy A Freitas @brandy-syglass.bsky.social · 30/07/2026

Non-destructive testing for #3DThursday! 🔬🥽 This scan shows how complex internal components can be inspected in 3D without disassembling or damaging the device. Also, come see me at M&M next week! #MM2026 🔬: Neptune Industrial X-ray CT Scan 🏛️: Lumafield @lumafield.bsky.social 🎬: syGlass.io, v2.7.1

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Brandy A Freitas @brandy-syglass.bsky.social · 23/07/2026

We’re heading to #2026SDB in Vegas this week! 🎲🧬Come find us and say hi for #3DThursday! 🔬: Bruker MuVi-SPIM (LSFM) @brukerspatial.bsky.social 🥼: Shirley Song, Michael Barresi, 2025, tracking dividing cells with lineage in syGlass 🏛️: Smith College 🎬: #syGlass, v2.7.0 @socdevbio.bsky.social

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Brandy A Freitas @brandy-syglass.bsky.social · 16/07/2026

This #3DThursday, our first syGlass 6DOF stylus kits are heading to researchers around the world! Built with #Antilatency after a lot of development and testing, the high-precision tracking lets you move, slice, annotate, and analyze 3D data naturally on the #Sony SRD. 🖊️📺 #syGlass #Microscopy

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Brandy A Freitas @brandy-syglass.bsky.social · 09/07/2026

🎉 New for #3DThursday: #syGlass Learn is here! We’re bringing interactive anatomy curriculum to standalone VR headsets, with expert-guided lessons, immersive assessments, and a much easier way to deploy VR learning. Try it on the Meta Quest Store: www.meta.com/experiences/... #Anatomy #EdTech #VR

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Brandy A Freitas @brandy-syglass.bsky.social · 02/07/2026

The #syGlass summer release is here for #3DThursday! ☀️ This update adds new ways to landmark, interact with, track, and explore complex 3D/4D data. Full post: www.syglass.io/blog/syglass... Huge thanks to Michael Barresi for the data used in the new splash screen! #VirtualReality #SciComm

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Brandy A Freitas @brandy-syglass.bsky.social · 25/06/2026

🔬 For #3DThursday: a whole cleared mouse embryo imaged with DALISPIM from @lifecanvastech.bsky.social A theme from #FOM2026 + #ELMI2026 was that light microscopy innovation can come from rethinking imaging geometries, in this case an open-top inverted #lightsheet. 🎬: #syGlass v2.6.0

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Brandy A Freitas @brandy-syglass.bsky.social · 18/06/2026

#MicroCT of a soybean bud complex for #3DThursday! 🌱 pollen-filled anthers arranged around the ovary that contains the ovules. 🔬 @zeiss-microscopy.bsky.social Xradia 520 Versa 🥼 @cygnusplantxray.bsky.social Keith Duncan 🏛️ @danforthcenter.bsky.social 🎬 #syGlass v2.6.0 #PlantScience #3DImaging

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Brandy A Freitas @brandy-syglass.bsky.social · 11/06/2026

Mouse spine data #3DThursday from our partners at 3i! 🎉 Specimen from Pantelis Tsoulfas, imaged at #LSFM26 on 3i’s AxL light sheet. Axial sweeping helps preserve whole-spine context while improving optical sectioning across a thick cleared specimen. #syGlass @the.3i.social @univmiami.bsky.social

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Brandy A Freitas @brandy-syglass.bsky.social · 04/06/2026

For #3DThursday, this is a 99-million-year-old earwig preserved in Burmese amber from the Sims Collection! 🔬: Miltenyi Biotec Blaze 🥼: Samuel Harrison 🪲: Jim Sims from Hamamatsu 🎬: #syGlass, v2.6.0 🏛️: #LSFM26, MDI @mdibl.org @hamamatsucorp.bsky.social @miltenyibiotec.bsky.social #scicomm #LSFM

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Brandy A Freitas @brandy-syglass.bsky.social · 28/05/2026

🌌 Live painted sea urchin data for #3DThursday, ahead of #LSFM26 at MDI! 🔬: Bruker TruLive3D, light sheet microscopy, imaged over 12 hours in 1% agarose 🥼: Amro Hamdoun, from Tzer Han Tan's group at UC San Diego, data from Dane Maxfield 🎬: #syGlass, v2.6.0 @lsfm-na.bsky.social @mdibl.org #scicomm

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Brandy A Freitas @brandy-syglass.bsky.social · 14/05/2026

📚 Good imaging comes from people being generous with what they know. Course season! #AQLM at MBL last week, #QFM in Bar Harbor next week, and I’ll be at #LSFM with a paddleboard + Sony screen. Here’s a light sheet medley of favorite 3D/4D datasets from this year! #syGlass #3DThursday

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Brandy A Freitas @brandy-syglass.bsky.social · 11/05/2026

🥹 Still feeling grateful after #HarvardXR 2026, where syGlass won Best Emerging XR Startup and Best Applied XR Product. 🏆🏆 Thank you to the organizers and judges for a thoughtful, energizing event! #syGlass #HXR2026 #XR #AppliedXR #ScienceViz #3D www.syglass.io/blog/syglass...

syglass.io

syGlass Wins Two Awards at HarvardXR 2026 — syGlass

syGlass was honored with two awards—Best Applied XR Product and Best Emerging XR Startup—at HarvardXR 2026.

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Brandy A Freitas @brandy-syglass.bsky.social · 07/05/2026

For #3DThursday: a ~5 mm Parhyale hawaiensis female (with hatchlings!) imaged by #nanoCT. 🔍🦐 This tiny amphipod is a powerful #devbio model organism. 🥼 Neeharika Verma, Nipam Patel Lab 🔬 @zeiss-microscopy.bsky.social Versa 620 XRM 🏛️ @mblscience.bsky.social, UF Nanoscale Research Facility 🎬 #syGlass

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Brandy A Freitas @brandy-syglass.bsky.social · 30/04/2026

🦎 A gorgeous Axolotl dataset for #3DThursday before I head to MBL for #NESDB2026. Those are tiny shrimps 🦐 in its stomach! 🔬: ZEISS Xradia 520 #microCT 🥼: Claudio Polisseni 🏛️: Max Planck Institute for Biological Intelligence @mpiforbi.bsky.social 🎬: #syGlass v2.6.0 @mblscience.bsky.social #Zeiss

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Brandy A Freitas @brandy-syglass.bsky.social · 23/04/2026

🧠 Microscopy data are getting huge and increasingly hard to work with (this ex vivo human brain MRI dataset was ~8 TB!). In #syGlass, we use out-of-core octree rendering to stream only what you see, keeping VR interactive even at this scale. 🔬 7T MRI | 🏛️ MGH | BL Edlow et al #Microscopy #3DThursday

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Brandy A Freitas @brandy-syglass.bsky.social · 16/04/2026

Ray casting for #3DThursday! 🔦 🦎 Veiled chameleon embryo, microCT 🥼 Raul Diaz 🎬 #syGlass v2.6.0 Direct volume rendering works on voxel data directly—casting a ray per pixel and combining signal along its path. Different models (MIP, average, absorption) highlight different structures + depth.

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Brandy A Freitas @brandy-syglass.bsky.social · 13/04/2026

We won! 🏆🥹 syGlass took Best Emerging XR Startup + Best Applied XR Product at #HarvardXR this weekend. Best part (besides surviving the pitch 💀) was live demos on the #Sony Spatial Reality Display, including this #microCT of a chameleon embryo from R Diaz More soon 👀 #XR #3DVisualization #syGlass

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Brandy A Freitas @brandy-syglass.bsky.social · 09/04/2026

#UMAP in VR for #3DThursday! In this zebrafish embryogenesis dataset, RNA-seq + ATAC-seq across 94k+ cells reveal changing regulatory programs over time. 🥼 Yang-Joon Kim, Loic Royer @loicaroyer.bsky.social , Matthias Haury 📝 www.biorxiv.org/content/10.1... 🏛️ Biohub @biohub.org 🎬 #syGlass v2.6.0

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Brandy A Freitas @brandy-syglass.bsky.social · 02/04/2026

Happy #3DThursday from Sweden! 🇸🇪 This Thy-1 mouse brain was the crowd favorite at Focus on Microscopy this year 🐭 🔬: Zeiss Lightsheet Z.1 🥼: Chih-Wei Logan Hsu @cwloganhsu.bsky.social 🏛️: Baylor College of Medicine 🎬: syGlass, v2.6.0 #FOM2026 #syGlass #Microscopy @scilifelab.se

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Brandy A Freitas @brandy-syglass.bsky.social · 26/03/2026

Fun #3DThursday update: #syGlass now supports the #Sony Spatial Reality Display! 🎉📺 Glasses-free 3D—no headset needed. Just walk up, look, and see depth instantly. A powerful new way to share scientific data with researchers, students, and the public. #3DVisualization #SciComm #EdTech

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Brandy A Freitas @brandy-syglass.bsky.social · 23/03/2026

Super excited for this! I love his data ... join us on April 10th for the Spring Symposium: www.nesmicroscopy.org/2026-spring-...

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Brandy A Freitas @brandy-syglass.bsky.social · 19/03/2026

☘️ A special #3DThursday for St Patrick's: Beer foam evolving in 4D in a microCT! 🍻 This is a Belgian Duvel (sorry not Irish...) from @tescan.bsky.social + Wesley De Boever Who’s off to #FOM2026 in Stockholm? I'll be there next week! www.focusonmicroscopy.org #Microscopy #MicroCT #Imaging #syGlass

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Brandy A Freitas @brandy-syglass.bsky.social · 12/03/2026

Streaming OME-Zarr data directly into syGlass for #3DThursday🌍🔬 With #syGlass v2.6.0, datasets can stream from disk, S3, or HTTPS with no massive downloads required. Huge thanks to the community building open imaging standards: @openmicroscopy.org #OMEZarr #Microscopy #OpenScience #Bioimaging

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Brandy A Freitas @brandy-syglass.bsky.social · 05/03/2026

The fruit fly of plant science for #3DThursday! 🌱 #ModelOrganism 🔬: #microCT, Zeiss @zeiss-microscopy.bsky.social Versa 520 XRM (contrast-enhanced with OsO₄) 🌱: Arabidopsis thaliana 🥼: Keith Duncan @cygnusplantxray.bsky.social 🏛️: Danforth Center @danforthcenter.bsky.social 🎬: syGlass.io #syGlass

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New England Society for Microscopy @nesmicroscopy.bsky.social · 03/03/2026

📣 Announcing our #NESM Spring Symposium — April 10 (virtual & free!) We’re building an exciting lineup across the life & physical sciences. Interested in giving a talk? Submit your abstract by March 25 🗓️ Register: www.nesmicroscopy.org/2026-spring-... #Microscopy #Bioimaging

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Brandy A Freitas @brandy-syglass.bsky.social · 26/02/2026

New in syGlass for #3DThursday: a VR surface brush for editing meshes🖌️Here, I’m isolating a component from a @lumafield.bsky.social #microCT scan of a VR headset, painting partitions directly onto the surface and exporting clean .OBJs: v2.6.0 #VR #3DVisualization #syGlass #ScientificVisualization

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Brandy A Freitas @brandy-syglass.bsky.social · 19/02/2026

syGlass v2.6.0 is out for #3DThursday! ❄️ 🖥️ Sony Spatial Reality Display support ☁️ Direct OME-Zarr streaming from disk, S3, or HTTPS 🖌️ VR surface partition brush ⌨️ In-VR keyboard & numpad 🎮 Saved tool loadouts www.syglass.io/blog/syglass... #syGlass #Bioimaging #VR #3DData #OMEZarr #Sony

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Brandy A Freitas @brandy-syglass.bsky.social · 12/02/2026

❤️ A cleared guinea pig heart for #3DThursday! Clearing a heart is HARD — dense muscle, deep antibody labeling, big volume. But to understand coronary networks, you need the whole organ. 🔬: Miltenyi Ultramiscroscope 🥼: Pam Rios Coronado, @pamrc.bsky.social 🏛️: Red-Horse lab @stanford.edu 🎬: #syGlass

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Brandy A Freitas @brandy-syglass.bsky.social · 09/02/2026

Yes! Anyone doing microscopy in New England (or anywhere in the world!), we would love to feature your work. 🤗

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Brandy A Freitas @brandy-syglass.bsky.social · 05/02/2026

🌕 Exploring a 3.6-billion-yo moon rock for #3DThursday! Showing how we can virtually slice through the volume, inspect internal structures, and take 3D measurements from #XCT data. 🔬: #Nikon XTH320 Scanner 🥼: Zoë Wilbur 🏛️: #NASA JSC Astromaterials X-ray Computed Tomography Lab 🎬: #syGlass, v2.5.0

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Brandy A Freitas @brandy-syglass.bsky.social · 29/01/2026

Running TotalSegmentator inside #syGlass for #3DThursday! 🔬 Automated segmentation needs strong clinical data for training and benchmarking, plus models that generalize. Mayo Clinic Low Dose CT Grand Challenge + #TotalSegmentator by Jakob Wasserthal are great examples. #MedicalImaging #3DImaging

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Brandy A Freitas @brandy-syglass.bsky.social · 22/01/2026

The Allen Mouse Brain Atlas is a cornerstone of #neuroscience: a standardized, high-resolution map of brain anatomy built to keep experiments comparable across labs. 🧠 Here’s a 3D walk through its anatomical meshes in #syGlass! @alleninstitute.org #3DThursday #DataViz #VR

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Brandy A Freitas @brandy-syglass.bsky.social · 15/01/2026

For #3DThursday, a skeleton shrimp imaged on a Flamingo light sheet microscope — a modular, traveling #LSFM built to bring the microscope to the biology.🔬🦩Fast 3D imaging, low phototoxicity. 🥼: Carsten Wolff @carsten-wolff.bsky.social 📝: huiskenlab.com/flamingo/ 🏛️: @morgridgeinstitute.bsky.social

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Brandy A Freitas @brandy-syglass.bsky.social · 08/01/2026

🪰 For #3DThursday, this #microCT scan of an adult #Drosphila (Schoborg et al.) captures the entire fly intact. Using #VR, we can teach anatomy by labeling the 3D fly from a 2D diagram. Spatial context changes everything. #SciComm 🔬: Bruker SkyScan 1172 🏛️: UWyoming 🎬: #syGlass, v2.5.0

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Brandy A Freitas @brandy-syglass.bsky.social · 01/01/2026

2025 took us around the world 🌍 From Zurich to Beijing, London, Paris, Montreal, all over the Americas, we explored scientific datasets in VR with the researchers who created them -- and pushed #syGlass to new limits for 3D analysis. On to 2026. 🔬✨ #3DThursday #Microscopy #ScientificImaging

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Brandy A Freitas @brandy-syglass.bsky.social · 25/12/2025

🎄 A canonical visualization dataset, revisited! This #CT Christmas tree (2001) became a classic for teaching & benchmarking volume rendering. I’ve brought it into #syGlass to explore how far #3Dvisualization has come — same data, new method. 🔬 #3DThursday Story: www.cg.tuwien.ac.at/page/xmas/

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Brandy A Freitas @brandy-syglass.bsky.social · 23/12/2025

Nice feature from NVIDIA on #syGlass at the MBL! Exciting to see AI, RTX GPUs, and VR coming together to explore massive 3D brain datasets, with high school students contributing to ongoing, cutting-edge neuroscience research. @mblscience.bsky.social blogs.nvidia.com/blog/mbl-hum...

blogs.nvidia.com

Marine Biological Laboratory Explores Human Memory With AI and Virtual Reality

The lab in Massachusetts is studying molecular mechanisms of human memory function powered by NVIDIA RTX GPUs, HP Z Workstations and virtual-reality technology.

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