iiinova — where your digital self keeps evolving

Reposted by Javier Boix

Pablo J. Sáez @pjsaez.bsky.social · 30/03/2026

Just because it's Monday, we love #microscopy & we love #mitochondria, the powerhouse of the #cell We videoed mito under the microscope to see their dynamics. Here they join forces! Ofc we <3 the other #organelles too (to prevent jealousy) From @cellcommlab.bsky.social 🧪🔬 @focalplane.bsky.social

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Reposted by Javier Boix

Journal of Experimental Medicine @jem.org · 23/06/2026

Al Jawazneh, Liebold, Leyk, Bosurgi et al. show that engulfment of bile acid–loaded hepatic parenchymal cells results in the transfer of bile acids to phagocytic #macrophages, altering their inflammatory profile. rupress.org/jem/article/... @pjsaez.bsky.social #Inflammation #Cholangitis

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Pablo J. Sáez @pjsaez.bsky.social · 04/06/2026

1 week to start🔥 New @focalplane.bsky.social webinar series focused on #CellMigration, register & join us▶️, it will be fun! pls spread the word, in the next one, ECRs could apply to show their work ;) ▶️ to register: focalplane.biologists.com/2026/05/29/n... @dgz.bsky.social @the-node.bsky.social

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Reposted by Javier Boix

FocalPlane @focalplane.bsky.social · 29/05/2026

We are excited to announce another new webinar series, this time on cell migration, hosted by @pjsaez.bsky.social & @valeriaventurini.bsky.social. In our 1st webinar, we’ll hear talks from @juanmagararc.bsky.social, @kyohalie.bsky.social & @djcohen.bsky.social. 🗓️11 June, 15:00 BST

focalplane.biologists.com

New webinar series on cell migration - FocalPlane

New webinar series on cell migration - News

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Javier Boix @jboixcampos.bsky.social · 22/05/2026

🧵 The AI industry is obsessed with making models bigger. I just made one 95% smaller, and it got better in the process ✨ 👇🏽👇🏽👇🏽

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Javier Boix @jboixcampos.bsky.social · 21/05/2026

🧵 Time for a new introduction, as a lot has changed in the last year! Hi! 👋 I'm Javier, ML Engineer and Biotechnologist, working at the intersection of efficient AI and biomedical research ⚛️🧬

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Pablo J. Sáez @pjsaez.bsky.social · 16/01/2026

#FluorescenceFriday Jost, Schweizer et al. @ Cuello lab found that a mutation linked to aortic aneurysmas led to distorted actin #cytoskeleton in VSMCs #mechanobiology New collab @cellcommlab.bsky.social by @jboixcampos.bsky.social🔥 Full www.sciencedirect.com/science/arti... #microscopy #cell 🧪🔬

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Pablo J. Sáez @pjsaez.bsky.social · 09/01/2026

Congrats to all authors, & collaborators @hfspo.bsky.social especially #NirGov Also thanks to those that allowed to promote our work, @dgz.bsky.social Here, a webinar I gave @tlmcambridge.bsky.social, in case someone is interested in the other aspects of the story. youtu.be/xorWG5Jh_8o?...

youtu.be

Pablo Sáez (University Medical Center Hamburg - Eppendorf) "Decision-making during cell migration"

YouTube video by Theory of Living Matter Group - Cambridge U

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Pablo J. Sáez @pjsaez.bsky.social · 09/01/2026

#FluorescenceFriday Proud of our the last paper @cellcommlab.bsky.social & 1st one of @jboixcampos.bsky.social We continue to study #CellMigration & how cells decide where to go: ↖️↗️⬇️? (movie of the actin #cytoskeleton) Full www.science.org/doi/10.1126/... @focalplane.bsky.social @science.org 🧪🔬

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Pablo J. Sáez @pjsaez.bsky.social · 07/01/2026

Congrats Javi @jboixcampos.bsky.social, you did a fantastic work, so it's very much deserved ! For the next one !

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Javier Boix @jboixcampos.bsky.social · 07/01/2026

Our work is finally published in @science.org Advances! 🎉 My very first paper, and what a journey it's been 🙂‍↕️ Huge thanks to the whole team, and especially to @pjsaez.bsky.social for believing in me. It turned out way better than I could've ever dreamt ✨ 📄 science.org/doi/10.1126/sciadv.ads2734

science.org

Trade-off between branching and polarity controls decision-making during cell migration

Highly branched cells require fine-tuning of polarity and shape dynamics to ensure balance between exploration and migration.

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Reposted by Javier Boix

Pablo J. Sáez @pjsaez.bsky.social · 01/01/2026

We combined cell biology, #AI based image analysis & a mathematical model to show how migratory behaviour changes with branching For now macrophages & endothelial cells, but we have many more, stay tuned ;) Kudos to all authors for the effort, especially to a great Padawan @jboixcampos.bsky.social

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Pablo J. Sáez @pjsaez.bsky.social · 01/01/2026

#HappyNewYear ! Let's start 2026 with a @cellcommlab.bsky.social paper How many branches is OK during #CellMigration? It depends on the #cell: for ex. immune cells are just fine. In collab. w. #NirGov @hfspo.bsky.social Full www.science.org/doi/10.1126/... @focalplane.bsky.social @science.org 🧪🔬

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Pablo J. Sáez @pjsaez.bsky.social · 04/12/2025

Hot from the press ! Happy to see this out, and that @cellcommlab.bsky.social contributed with live-cell imaging Autoimmunoglobulin-triggered extracellular vesicles (movie) contribute to kidney disease Full www.cell.com/cell/fulltex... @focalplane.bsky.social @cp-cell.bsky.social #microscopy 🧪🔬

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Reposted by Javier Boix

Pablo J. Sáez @pjsaez.bsky.social · 19/11/2025

Do you want to do some frontier of knowledge research? There's still time to register for the next webinar of @hfspo.bsky.social By far one of the best agencies I've worked with for my beloved HFSP project, even if it's a bumpy road...no risk no glory... www.hfsp.org/hfsp-events/...

hfsp.org

HFSP Webinar 2025: Research Grants | Human Frontier Science Program

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Javier Boix @jboixcampos.bsky.social · 21/08/2025

Learning mindset: every error teaches, every failed analysis provides insight, every solution deserves celebration! Growth through experimentation 🎯

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Javier Boix @jboixcampos.bsky.social · 18/08/2025

Perfect Sunday in Valencia: laptop in sunshine, working on analysis approaches! Sometimes the best office is wherever inspiration strikes 🌊

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Javier Boix @jboixcampos.bsky.social · 14/08/2025

Always explore existing tools before building from scratch! The open-source ecosystem is incredible. Standing on giants' shoulders = more time for research 🛠️

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Javier Boix @jboixcampos.bsky.social · 13/08/2025

Fascinating connection: medieval astronomical charts and modern computational biology plots both try to reveal hidden patterns in complex systems. Timeless challenge! ⭐

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Javier Boix @jboixcampos.bsky.social · 11/08/2025

Every computational biologist started with confused first attempts (and not only the first ones hahaha)! We all begin somewhere - keep learning and building 💪

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Javier Boix @jboixcampos.bsky.social · 07/08/2025

Data viz philosophy: your plot should tell a clear story immediately, not require lengthy explanation. Good visualization communicates instantly! 📊

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Javier Boix @jboixcampos.bsky.social · 06/08/2025

Taschen book insight: the best historical infographics combined accuracy with beauty. Modern data viz can learn from centuries of visual communication design! 🎨

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Javier Boix @jboixcampos.bsky.social · 04/08/2025

Computational biology = professional translation! Biological questions → math problems → computational analysis → biological insights. We're interpreters! 🔄

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Javier Boix @jboixcampos.bsky.social · 01/08/2025

August goals: improve data viz skills, explore new computational approaches, and keep building connections in the research community! 📈

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Javier Boix @jboixcampos.bsky.social · 30/07/2025

Love this perspective from Taschen's infographics history: every era had to solve the problem of making complex data understandable. Same challenge, evolving tools! 📈

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Javier Boix @jboixcampos.bsky.social · 28/07/2025

Appreciation for Streamlit! It makes building interactive data apps incredibly accessible! No web dev expertise needed to make analysis tools 🚀

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Javier Boix @jboixcampos.bsky.social · 25/07/2025

Computational thinking: breaking down complex biological questions into manageable components. It's problem-solving methodology beyond just programming! 🧠

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Javier Boix @jboixcampos.bsky.social · 23/07/2025

Reading about historical cartography: maps were the original interactive data visualizations! Navigation, territory, resources all encoded visually 🗺️

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Reposted by Javier Boix

Javier Boix @jboixcampos.bsky.social · 18/07/2025

I can't imagine a better day of the week to publish this than #FluorescenceFriday: PathoPlex is finally published! 🎉 This presents a revolutionary jump from 4-6 to 100+ markers per sample! 🤯 Read the full story here: www.nature.com/articles/s41...

nature.com

Pathology-oriented multiplexing enables integrative disease mapping - Nature

Pathology-oriented multiplexing (PathoPlex) represents a framework for widespread access to multiplexed imaging and computational image analysis of clinical specimens at a relatively high through...

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Reposted by Javier Boix

Pablo J. Sáez @pjsaez.bsky.social · 18/07/2025

More of other scientific research in #microscopy and #bioimaging in their brand new website: complextissue.com [ doi.org/10.1038/s415... ] Tks for the invite so the @cellcommlab.bsky.social could contribute with some #CellMigration, congrats to all authors #BskyScience #cellbio #diabetes #scicomm

complextissue.com

Complex Tissue Lab

Welcome to our lab. We focus on complex tissue analysis and intelligent algorithms for the interpretation of medical imaging data.

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Reposted by Javier Boix

Pablo J. Sáez @pjsaez.bsky.social · 18/07/2025

#HotFromThePress !! What if instead of analyzing 4-6 pathology markers you could check >100 in the *same* sample? @maltekuehl.com & co @puellesv.bsky.social lab introduce #PathoPlex, method that could even predict disease Full www.nature.com/articles/s41... @focalplane.bsky.social @nature.com 🧪🔬

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Javier Boix @jboixcampos.bsky.social · 18/07/2025

R isn't just for statistics - you can create beautiful visualizations and even art! The flexibility of ggplot2 continues to surprise me ✨

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Javier Boix @jboixcampos.bsky.social · 16/07/2025

Insight from the Taschen infographics book: da Vinci's Vitruvian Man is obviously early data visualization! Combining art, anatomy, and mathematical proportions. Data viz has deep roots ✨

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Javier Boix @jboixcampos.bsky.social · 15/07/2025

Computational biology insight: best solutions come from understanding biology first, then choosing appropriate math approaches. Domain knowledge matters! 🧬

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Javier Boix @jboixcampos.bsky.social · 12/07/2025

R package love: ggstatsplot continues to amaze me! Adding statistical results directly to visualizations makes data communication so much clearer 📊

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Javier Boix @jboixcampos.bsky.social · 08/07/2025

Valencia advantage: working outdoors year-round definitely helps with creative thinking! Currently planning new analysis approaches in the sunshine 🌅

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Javier Boix @jboixcampos.bsky.social · 05/07/2025

Weekend reflection: from studying biotechnology at UPV to working with computational methods. The intersection of biology and data science continues to fascinate me! ✨

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Pablo J. Sáez @pjsaez.bsky.social · 28/06/2025

Do you know what happens if you squeeze a #cell? If the #confinement is high, the nucleus (green) will be super tense & the compressed cells will react like this👇🏽changing their #cytoskeleton (magenta) Full: www.science.org/doi/10.1126/... #scicomm #microscopy #sciencesky @focalplane.bsky.social 🧪🔬

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Reposted by Javier Boix

Isaac Baumann @ibaumann.bsky.social · 01/07/2025

I love writing useful and descriptive commit messages

A list of commits with the messages "sort of final changes," "final commit probably," and "whoops forgot to add something"

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Javier Boix @jboixcampos.bsky.social · 01/07/2025

I'm currently reading "History of Information Graphics" by Sandra Rendgen to learn from centuries of visualization masters before creating new approaches for computational biology 🙂‍↕️ Improvable data communication wastes great research, and we can overcome that by standing on giants' shoulders! 📚✨

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Javier Boix @jboixcampos.bsky.social · 01/07/2025

🧵 Neural networks meet cell migration in Valencia! Hi Bluesky! 👋 I'm Javier, computational biologist @cellcommlab.bsky.social l working at the intersection of AI and cell biology 🖥️🧫

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DGZ.bsky.social @dgz.bsky.social · 11/04/2025

The next #DGZ Focus Workshop on #CellBiology of the #ImmuneSystem will take place on April 29, organized by @pjsaez.bsky.social & Evi Kiermaier – join us! 🧑‍🔬🧑‍🔬🧬

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Pablo J. Sáez @pjsaez.bsky.social · 29/04/2025

#CellMigration Join us today @dgz.bsky.social !! See you in 1 h (zoom id and password in the pic below)

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Pablo J. Sáez @pjsaez.bsky.social · 11/04/2025

Join us for this @dgz.bsky.social seminar online with very cool talks about the Cell biology of the immune system There will be of course some #CellMigration of leukocytes ;) Speakers: @liz-kurtz.bsky.social, #ZahraaA, @labliston.bsky.social and #StefanU

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Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM) @iib.uam.es · 24/03/2025

El #IIBmCSICUAM agradece a Pablo J. Sáez compartir sus conocimientos, y mostrarnos las preciosas imágenes, sobre los novedosos principios que rigen la migración celular @pjsaez.bsky.social @cellcommlab.bsky.social @csic.es @uam.es

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Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM) @iib.uam.es · 18/03/2025

Jueves, 20 de marzo ⏰ 12.30 SEMINARIO Ad Hoc en el #IIBmCSICUAM 📙 Pablo J. Sáez de la University Medical Center Hamburg-Eppendorf (UKE), Alemania, dará una conferencia 🗣️"Decision-making during cell migration” @pjsaez.bsky.social @cellcommlab.bsky.social @csic.es @uam.es

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Pablo J. Sáez @pjsaez.bsky.social · 06/02/2025

#CellMigration happens all the time in our bodies. This may (or not) rely on adhesion molecules #Cancer cells switch strategies during metastasis to invade other tissues Naomi Wee (naomiwee.com) did this neat movie to explain it: www.youtube.com/watch?v=D9aD... #SciSky 🧪🔬 @cellcommlab.bsky.social

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