Reposted by Edwin Antony
Transcript-wide m6A methylation defines the efficiency of cap-independent translation initiation
RNA (New York, N.Y.) · Smolin et al.
doi.org/10.1261/rna.081017.126
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doi.org
Transcript-wide m6A methylation defines the efficiency of cap-independent translation initiation
Here, we combined ribosome profiling under conditions of mTOR inhibition and m⁶A mapping to identify distinct subsets of mRNAs that differ in their sensitivity to the suppression of cap-dependent initiation.
