TAR DNA-binding protein-43 (TDP-43) alterations are a key hallmark of amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other neurodegenerative disorders. Increasing evidence lin...

University of California, San Francisco Online Faculty Recruitment

King’s College London seeks a Senior Lecturer to lead Alzheimer’s research focused on disease mechanisms and new treatment development.

MIT - Scientific Program Manager - Cambridge MA 02139

In this review, Sakers et al. discuss how astrocytes, microglia, and oligodendrocyte lineage cells actively regulate neural circuit formation, refinement, and stabilization. They propose that coordina...

These proposed Office of Management and Budget regulations would render the federal research grant review process opaque

The Williamson Lab studies astrocyte biology across development, cognition, and disease.

Astrocytes are wired together in precise, long-range networks that remodel in response to experience, according to new research.

A growing body of research suggests astrocytes, star-shaped brain cells once dismissed as support players, may lead the way to more precise and effective psychiatric drugs.

PhD Project - Astrocyte-Neuron Interactions in Neural Circuit Function and Dementia at Cardiff University, listed on FindAPhD.com

Here's why you should, and how to start

Delivanoglou et al. show that expression of APOE4, a risk factor for Alzheimer’s disease, leads to sexually dimorphic lymphatic and inflammatory responses in mice and humans alike. Suppressing APOE4-i...

The US Congress rejected sweeping cuts to science agencies. But the NIH, the NSF and NASA have had their spending slowed.

CRISPR–Cas9 screening identifies CLCC1 as a factor that increases neutral lipid flux to prevent hepatic steatosis and promotes nuclear pore complex assembly by promoting membrane bending and fusi...

A clause limiting the use of multiyear NIH grant funding has become a sticking point as the Senate appropriations panel finalizes the HHS spending bill

After spinal cord injury, lesion-remote astrocytes acquire heterogeneous, spatially restricted reactivity states that shape neuroinflammation, neural repair and neurological recovery.

Neurons are shown to use fatty acid β-oxidation as a fuel source for memory formation upon intensive learning in Drosophila, challenging the view that neurons are unable to use fatty acids for energy ...

Autism Spectrum Disorders (ASD) are associated with metabolic dysregulation. While astrocytes are integral to cerebral metabolism, their molecular and functional changes in ASD are poorly known. Using...

Lange et al. identify a lipid droplet quality control pathway in which FSP1 safeguards stored neutral lipids from lipid peroxidation, thereby preventing the induction of ferroptosis.

Metabolic inflexibility in Alzheimer's disease. Schematic illustrating the biphasic trajectory of metabolic activity relative to canonical Alzheimer's disease (AD) biomarkers. In the presymptomatic p...

Deciphering body-brain communication pathways is key to a deeper understanding of brain physiology and pathology. Here, the authors define the astrocyte endfoot proteome and show dynamic vascular-to-a...

Researchers have discovered that free radicals generated at a specific site in non-neuronal brain cells called astrocytes, may promote dementia, according to a Weill Cornell Medicine study.

Nature Metabolism, Published online: 04 November 2025; doi:10.1038/s42255-025-01391-xBy parsing stimulus-responsive sources of astrocytic reactive oxygen species (ROS), Barnett et al. reveal how mitochondrial complex III-derived signals uniquely shape inflammatory responses and astrocyte–neuron crosstalk, linking mitochondrial redox cues to dementia-related neurodegeneration.