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Nature Neuroscience

@natneuro.nature.com
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News, commentary and research coverage from the international monthly journal publishing the highest quality of work in all areas of neuroscience. www.nature.com/neuro

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Nature Neuroscience @natneuro.nature.com · 23/09/2026
Coverage of our recent paper on two parallel neural ectoderm progenitors www.nature.com/articles/d41...
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Nature Neuroscience @natneuro.nature.com · 01/09/2026
Our September issue is now live! www.nature.com/neuro/volume...
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Nature Neuroscience @natneuro.nature.com · 01/09/2026
@springernature.com has a new resource: Nature Briefing: Clinical Neurology brings together key clinical developments and research from the leading journals in a concise weekly newsletter. Sign-up is free! go.springernature.com/int1/briefin...
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Sign up for Nature Briefing: Clinical Neurology
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Nature Neuroscience @natneuro.nature.com · 17/08/2026
Exciting conference in London 13–15 Oct 2026: Reframing Precision Medicine: Innovation to Implementation We’ll explore how multi omics, AI & big data can move personalised care from promise to practice. Learn more at go.nature.com/471AdQb
go.nature.com
Reframing Precision Medicine: Innovation to Implementation | 13–15 October 2026
A Nature conference reimagining what it means to deliver truly personalised care in the next decade.
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Nature Neuroscience @natneuro.nature.com · 05/08/2026
Our August issue is online now! www.nature.com/neuro/volume...
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Nature Neuroscience @natneuro.nature.com · 30/07/2026
🎉We're excited to welcome Qingzhong Ren to our editorial team! Qingzhong is based in our Shanghai office and is handling papers related to neurodegeneration, aging, and cellular and molecular neuroscience.
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Reposted by Nature Neuroscience
Shari Wiseman @shariwiseman.bsky.social · 07/07/2026
If you're at #FENS2026 and want to chat about @natneuro.nature.com, I'll be at the @springernature.com booth (#62) today, Wednesday, and Thursday from 10-12. Come say hi!
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Nature Neuroscience @natneuro.nature.com · 07/07/2026
Our July issue is online now! www.nature.com/neuro/volume...
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Nature Neuroscience @natneuro.nature.com · 02/07/2026
Our Chief Editor, Shari Wiseman @shariwiseman.bsky.social, will be at the @fens.org meeting in Barcelona next week! Get in touch with her if you'd like to chat about your work! #FENS2026
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Nature Neuroscience @natneuro.nature.com · 23/06/2026
This conference will explore the intersection of human cognition, mental health and artificial intelligence, bringing together researchers from diverse fields, including psychology, neuroscience, psychiatry, sociology, cultural evolution, and beyond. natureconferences.streamgo.live/the-human-mi...
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Nature Neuroscience @natneuro.nature.com · 08/06/2026
Check out our June issue! www.nature.com/neuro/volume...
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Nature Neuroscience @natneuro.nature.com · 08/05/2026
Check out our May issue! www.nature.com/neuro/volume...
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Nature Neuroscience @natneuro.nature.com · 01/05/2026
📢 We’re excited for the launch of npj Pain — a new open access @NaturePortfolio journal 📄 Broad scope spanning basic to clinical research, ethics & policy 🌍 Led & edited by a global team of researchers 📬 Submit at: nature.com/npjpain #PainResearch
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Nature Neuroscience @natneuro.nature.com · 13/04/2026
Our April issue is now live! www.nature.com/neuro/volume...
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Nature Neuroscience @natneuro.nature.com · 23/03/2026
Nature Progress Brain Health, a new open-access journal publishing impactful research in brain health, spanning translational neuroscience, neurology and neuropsychiatry, is now live! www.nature.com/natprogbrain...
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Nature Neuroscience @natneuro.nature.com · 12/03/2026
Exciting opportunity to help launch Nature Progress Brain Health! Must be able to work from our Shanghai, Beijing, or Pune offices. springernature.wd3.myworkdayjobs.com/SpringerNatu...
springernature.wd3.myworkdayjobs.com
Associate or Senior Editor Nature Progress Brain Health)
Job Title: Associate or Senior Editor Nature Progress Brain Health Location: Shanghai, Beijing or Pune, Hybrid Working Model Application Deadline: Mar 26th, 2026 About Springer Nature Springer Nature ...
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Nature Neuroscience @natneuro.nature.com · 09/03/2026
Check out our March issue! www.nature.com/neuro/volume...
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Nature Neuroscience @natneuro.nature.com · 17/02/2026
🚨We're hiring a new editor!🚨 We're especially looking for someone with expertise in neurodegeneration and cellular/molecular neuroscience. Must have a Ph.D. and be able to work from Madrid, Shanghai, or Pune. Deadline to apply is March 9. springernature.wd3.myworkdayjobs.com/SpringerNatu...
springernature.wd3.myworkdayjobs.com
Associate or Senior Editor, Nature Neuroscience
Job Title: Associate or Senior Editor, Nature Neuroscience Locations: Madrid, Shanghai and Pune Application Deadline: March, 9th 2026 candidates will be considered as they apply About Springer Nature ...
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Nature Neuroscience @natneuro.nature.com · 07/01/2026
Explore our January issue! www.nature.com/neuro/volume...
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Reposted by Nature Neuroscience
The Transmitter @thetransmitter.bsky.social · 15/12/2025
Check out “Frameshift,” a Q&A series in which neuroscientists with nontraditional careers discuss their work and how they made the transition away from the lab. In the first entry of the series, @shariwiseman.bsky.social shares how she went from the bench to science publishing. bit.ly/4rZkk5S
bit.ly
Frameshift: Shari Wiseman reflects on her pivot from science to publishing
As chief editor of Nature Neuroscience, Wiseman applies critical-thinking skills she learned in the lab to manage the journal’s day-to-day operations.
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Nature Neuroscience @natneuro.nature.com · 03/12/2025
Don't sleep on our December issue! www.nature.com/neuro/volume...
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Nature Neuroscience @natneuro.nature.com · 25/11/2025
Connectome caricatures remove large-amplitude coactivation patterns in resting-state fMRI to emphasize individual differences www.nature.com/articles/s41...
nature.com
Connectome caricatures remove large-amplitude coactivation patterns in resting-state fMRI to emphasize individual differences - Nature Neuroscience
Dominant coactivation patterns are primarily studied in resting-state fMRI. Here, the authors study the rest of the signal, which reveals ‘caricatured’ connectomes with improved behavioral prediction.
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Nature Neuroscience @natneuro.nature.com · 24/11/2025
Laser-engineered PRIME fiber for panoramic reconfigurable control of neural activity www.nature.com/articles/s41...
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Laser-engineered PRIME fiber for panoramic reconfigurable control of neural activity - Nature Neuroscience
The authors develop a neural probe with over 1,000 light emitters arranged along its length and circumference, enabling panoramic 3D optical stimulation across large brain volumes.
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Nature Neuroscience @natneuro.nature.com · 20/11/2025
Parietal cortex output neurons form a specialized population code that enhances the propagation of information to a downstream target and potentially improves the accuracy of decision-making www.nature.com/articles/s41...
nature.com
Specialized structure of neural population codes in parietal cortex outputs - Nature Neuroscience
Cortical neurons comprising an output pathway form a specialized population code that enhances the propagation of information to a downstream target, potentially improving the accuracy of decision-mak...
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Nature Neuroscience @natneuro.nature.com · 18/11/2025
Chief Editor Shari Wiseman @shariwiseman.bsky.social will be at the @springernature.com booth (#2220, look for the picture of a woman rock-climbing) from 2-4 today and from 10-12 tomorrow. Come stop by! #SfN2025
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Nature Neuroscience @natneuro.nature.com · 14/11/2025
TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD www.nature.com/articles/s41...
nature.com
TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD - Nature Neuroscience
TDP-43 dysfunction in ALS/FTD causes faulty splicing of the KCNQ2 ion channel, leading to toxic protein buildup, neuron hyperactivity and a potential new biomarker and treatment target using RNA-based...
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Nature Neuroscience @natneuro.nature.com · 13/11/2025
Chief Editor Shari Wiseman @shariwiseman.bsky.social will be at the @sfn.org meeting! She'll be at the @springernature.com booth (#2220) from 2-4 pm on Sunday and Tuesday, and from 10 am-12 pm on Monday and Wednesday. If you’d like to set up a one-on-one meeting, please email her. #SfN2025
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Nature Neuroscience @natneuro.nature.com · 12/11/2025
Attentional failures during wakefulness after sleep deprivation are tightly orchestrated in a series of brain–body changes, including neuronal shifts, pupil constriction and cerebrospinal fluid (CSF) flow pulsations @lauradata.bsky.social @ziy027.bsky.social www.nature.com/articles/s41...
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Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics - Nature Neuroscience
Yang et al. show that moments of failed attention we experience after sleep deprivation reflect brief ‘sleep-like’ episodes in the brain, corresponding to a brain- and body-wide event with altered bra...
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Nature Neuroscience @natneuro.nature.com · 12/11/2025
🥳Please join us in welcoming Ana Uzquiano @uzquianoa.bsky.social to our editorial team! Ioana is handling transcriptomics, neurodevelopment, and cellular and molecular neuroscience. She's based in the Madrid office.
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Nature Neuroscience @natneuro.nature.com · 11/11/2025
The brain’s wake-to-sleep transition follows bifurcation dynamics with a distinct tipping point preceded by a critical slowing down www.nature.com/articles/s41...
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Falling asleep follows a predictable bifurcation dynamic - Nature Neuroscience
Li et al. propose a conceptual framework to study the phenomenon of falling asleep based on electroencephalogram data. They show that a tipping point marks the brain’s nonlinear wake-to-sleep transiti...
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Nature Neuroscience @natneuro.nature.com · 10/11/2025
Connectome datasets alone are generally not sufficient to predict neural activity. However, pairing connectivity information with neural recordings can produce accurate predictions of activity in unrecorded neurons www.nature.com/articles/s41...
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Prediction of neural activity in connectome-constrained recurrent networks - Nature Neuroscience
The authors show that connectome datasets alone are generally not sufficient to predict neural activity. However, pairing connectivity information with neural recordings can produce accurate predictio...
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Nature Neuroscience @natneuro.nature.com · 06/11/2025
Longitudinal measures of monkey brain structure and activity through adolescence predict cognitive maturation @cconstan.bsky.social www.nature.com/articles/s41...
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Longitudinal measures of monkey brain structure and activity through adolescence predict cognitive maturation - Nature Neuroscience
Working memory improves during adolescent brain development. Zhu et al. tracked monkeys through adolescence, revealing that maturation of white matter tracts and refinement of neural firing patterns s...
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Nature Neuroscience @natneuro.nature.com · 05/11/2025
Large-scale chromatin accessibility profiling (ATAC-seq) of neurons and non-neurons from 2 human neocortical regions from 469 unique donors, comprising controls and individuals diagnosed with schizophrenia and bipolar disorder www.nature.com/articles/s41...
nature.com
The neuronal chromatin landscape in brains from individuals with schizophrenia is linked to early fetal development - Nature Neuroscience
This study maps chromatin accessibility in neurons and glia in schizophrenia, revealing fetal-like regulatory patterns in adult neurons enriched for genetic risk variants, linking early brain developm...
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Nature Neuroscience @natneuro.nature.com · 04/11/2025
Cortical and subcortical mapping of the human allostatic–interoceptive system using 7 Tesla fMRI www.nature.com/articles/s41...
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Cortical and subcortical mapping of the human allostatic–interoceptive system using 7 Tesla fMRI - Nature Neuroscience
The brain is constantly monitoring the systems in the body. Here the authors use 7 Tesla functional magnetic resonance imaging to map a large-scale brain system for body regulation in humans, includin...
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Nature Neuroscience @natneuro.nature.com · 04/11/2025
Our November issue is now live! www.nature.com/neuro/volume...
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Nature Neuroscience @natneuro.nature.com · 03/11/2025
Characterization of the circadian translatomes of astrocytes and microglia in mouse cortex in the setting of amyloid pathology or aging, revealing cell and disease-specific circadian reprogramming of neurodegeneration-related pathways www.nature.com/articles/s41...
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A glial circadian gene expression atlas reveals cell-type and disease-specific reprogramming in response to amyloid pathology or aging - Nature Neuroscience
Sheehan et al. have characterized the circadian translatomes of astrocytes and microglia in the mouse cortex in the context of amyloid pathology or aging, revealing cell- and disease-specific reprogra...
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Nature Neuroscience @natneuro.nature.com · 31/10/2025
A pair of papers on how TDP-43 loss in ALS/FTD causes changes in mRNA polyadenylation This one from Aaron Gitler's group www.nature.com/articles/s41...
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TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes - Nature Neuroscience
Zeng et al. show that TDP-43, known for repressing cryptic exon usage in frontotemporal dementia/amyotrophic lateral sclerosis, also controls alternative polyadenylation, impacting expression of disea...
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Nature Neuroscience @natneuro.nature.com · 30/10/2025
Leptin-sensitive neuronal subpopulations in the lateral hypothalamus enable adaptive fulfillment of vital needs despite anxiogenic conditions www.nature.com/articles/s41...
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A lateral hypothalamic neuronal population expressing leptin receptors counteracts anxiety to enable adaptive behavioral responses - Nature Neuroscience
Figge-Schlensok et al. show that leptin-sensitive neurons in the lateral hypothalamus encode anxiogenic stimuli and facilitate adaptive strategies to enable an animal to overcome anxiety in threatenin...
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Nature Neuroscience @natneuro.nature.com · 29/10/2025
Oxytocin modulates respiratory heart rate variability through a hypothalamus–brainstem–heart neuronal pathway @julie.buron.bsky.social @inmed.bsky.social @insermpacacorse.bsky.social D54@incia-neurocampus.bsky.social www.nature.com/articles/s41...
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Oxytocin modulates respiratory heart rate variability through a hypothalamus–brainstem–heart neuronal pathway - Nature Neuroscience
Buron et al. show that oxytocin enhances heart rate variability linked to breathing during recovery from stress. This calming and cardio-protective effect is produced through a hypothalamus–brainstem ...
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Nature Neuroscience @natneuro.nature.com · 27/10/2025
🥳Please join us in welcoming Ioana Marin to our editorial team! Ioana is handling neuroimmunology and cellular and molecular neuroscience. She's based in the NYC office.
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Nature Neuroscience @natneuro.nature.com · 27/10/2025
High-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN), a common target for Parkinson’s disease, activates afferent axons while inhibiting STN neurons www.nature.com/articles/s41...
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Differential synaptic depression mediates the therapeutic effect of deep brain stimulation - Nature Neuroscience
The authors show that deep brain stimulation (DBS) inhibits local neural activity via differential suppression of glutamate and GABA release, and they developed a chemogenetic therapy as a less invasi...
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Nature Neuroscience @natneuro.nature.com · 24/10/2025
A noninvasive, CSF-specific MRI technique that enables detailed in vivo measurement of CSF mobility in humans, down to the level of perivascular spaces located around penetrating vessels www.nature.com/articles/s41...
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Region-specific drivers of CSF mobility measured with MRI in humans - Nature Neuroscience
Brain clearance mechanisms are challenging to visualize in humans. Using magnetic resonance imaging, the authors noninvasively mapped cerebrospinal fluid motion across the brain, showing region-specif...
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Nature Neuroscience @natneuro.nature.com · 23/10/2025
C9orf72 mutations impair immune activation in ALS, highlighting key differences in the cellular and molecular pathways underlying sporadic and genetics forms of the disease @mancusorenzo.bsky.social @c9laura72.bsky.social @baukje-bij.bsky.social @cmn-vib.bsky.social www.nature.com/articles/s41...
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C9orf72 hexanucleotide repeat expansions impair microglial response in ALS - Nature Neuroscience
This study shows that C9orf72 mutations impair immune activation in ALS, affecting how brain cells communicate, and highlights key differences in the cellular and molecular pathways underlying sporadi...
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Nature Neuroscience @natneuro.nature.com · 23/10/2025
Nature Neuroscience is happy to now offer Transparent Peer Review, in which authors can choose for us to publish details about the peer review process (including reviews, rebuttal letters, and editorial decision letters). More info at the link below: www.nature.com/neuro/editor...
nature.com
Peer Review | Nature Neuroscience
Peer Review
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Nature Neuroscience @natneuro.nature.com · 22/10/2025
Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of mouse and human brain function @adamqbauer.bsky.social @jordacular.bsky.social @realjoshsiegel.bsky.social @oliverk28.bsky.social www.nature.com/articles/s41...
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Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of brain function - Nature Neuroscience
Padawer-Curry et al. show that the hallucinogenic 5-HT2A receptor agonist DOI alters neurovascular coupling in mice, with implications for the interpretation of human fMRI studies of psychedelics.
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Nature Neuroscience @natneuro.nature.com · 21/10/2025
Astrocytic Ca2+ prevents synaptic depotentiation by limiting repetitive activity in dendrites during motor learning @baolinglai.bsky.social www.nature.com/articles/s41...
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Astrocytic Ca2+ prevents synaptic depotentiation by limiting repetitive activity in dendrites during motor learning - Nature Neuroscience
Lai et al. show a function of astrocytic Ca2+ in preventing synaptic depotentiation by reducing repetitive dendritic activity in the motor cortex during motor training, thereby contributing to learnin...
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Nature Neuroscience @natneuro.nature.com · 10/10/2025
Brain tumors induce widespread disruption of calvarial bone and alteration of skull marrow immune landscape www.nature.com/articles/s41...
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Brain tumors induce widespread disruption of calvarial bone and alteration of skull marrow immune landscape - Nature Neuroscience
Glioblastoma—the deadliest form of brain cancer—alters the calvarial bone and its marrow components, pushing it toward producing more myeloid cells and contributing to an immunosuppressive environment.
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Nature Neuroscience @natneuro.nature.com · 09/10/2025
Muscle-derived miR-126 regulates TDP-43 axonal local synthesis and NMJ integrity in ALS models www.nature.com/articles/s41...
nature.com
Muscle-derived miR-126 regulates TDP-43 axonal local synthesis and NMJ integrity in ALS models - Nature Neuroscience
Ionescu, Ankol et al. show that, in ALS mouse and iPSC models, TDP-43 aggregation at NMJs stems from aberrant axonal translation, normally repressed by muscle EV-derived miR126. Loss of miR126 in ALS increases TDP-43 buildup, impairs local synthesis and triggers degeneration.
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Reposted by Nature Neuroscience
Springer Nature @springernature.com · 07/10/2025
Want to close the gender gap in research? Start with the data. Our Springer Nature report: Closing the Gender Gap highlights where change is needed most — and how you can be part of it. Read the report: spklr.io/63324ByG4y
Against a red backdrop, geometric shapes accent the title, "Closing the Gender Gap," with the subtitle, "Peer Review at Nature Portfolio". The shapes include circles and rectangles of white, blue, green, and brown.
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Nature Neuroscience @natneuro.nature.com · 07/10/2025
A single dose of #psilocybin induces a rapid and sustained reversal of both mechanical allodynia (pain) and anxiodepression-like states in adult male and female mice www.nature.com/articles/s41...
nature.com
Single-dose psilocybin rapidly and sustainably relieves allodynia and anxiodepressive-like behaviors in mouse models of chronic pain - Nature Neuroscience
Hammo et al. show that a single dose of psilocybin rapidly and sustainably relieves both chronic pain and anxiodepressive-like behaviors in mice by restoring prefrontal activity through partial agonism at 5-HT2A and 5-HT1A receptors.
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