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UK Dementia Research Institute

@ukdri.ac.uk
857 followers 194 following 304 posts

The UK’s leading research institute transforming the lives of people affected by neurodegenerative conditions. Principally funded by the Medical Research Council.

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UK Dementia Research Institute @ukdri.ac.uk · 15/09/2026
A pleasure to welcome @sdoughtymp.bsky.social to UK DRI at Cardiff, showcasing the world-leading research taking place here in Wales to accelerate understanding and develop better diagnostics and treatments for everyone living with dementia.
Stephen Doughty MP met with Prof Baljit Khakh, Prof Wendy Larner, Prof Siddharthan Chandran, and Prof Roger WhitakerCentre Director Prof Khakh demonstrates how breakthroughs in imaging technology are unlocking new areas of researchDr Hazel Hall Roberts is shows how iPSC research informs better understanding of Alzheimer's riskStephen Doughty MP met with early career researchers to discuss the life science ecosystem in Cardiff and the opportunities of being part of UK DRI
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UK Dementia Research Institute @ukdri.ac.uk · 04/09/2026
⭐️The UK DRI at Imperial is hiring for a 3-year PhD studentship within Dr Cynthia Sandor’s group⭐️ The project will focus on 'Predicting Insulin Resistance from Blood Transcriptomes: A Peripheral Window onto Brain Insulin Resistance in Parkinson’s & Alzheimer’s Disease'. More info: 🔗 buff.ly/HJ2LiWw
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UK Dementia Research Institute @ukdri.ac.uk · 28/08/2026
⭐️ The UK DRI at UCL is hiring ⭐️ We are seeking a Centre Research Administrator to support the Centre Manager with high-quality operational and administrative support, helping to ensure the smooth running of the Centre. 🔗 www.ucl.ac.uk/work-at-ucl/... @uclqsion.bsky.social
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UK Dementia Research Institute @ukdri.ac.uk · 25/08/2026
What role do supporting brain cells play in cognitive decline and dementia? 🧠 New research led by @mironlab.bsky.social finds cells that produce the protective coating around nerve fibres (oligodendrocytes) can become dysfunctional with age & may contribute to cognitive decline👉 lnkd.in/eWcnSfnf
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Soyon Hong @soyonhonglab.bsky.social · 20/08/2026
We argue that understanding how NI crosstalk become dysregulated in NDD & how they might be restored offers powerful framework re: disease mechanisms & therapeutic opportunities. Thanks @chanzuckerberg.bsky.social and the pioneering neuroimmunologists at the CZI workshop for shaping our thinking!
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UK Dementia Research Institute @ukdri.ac.uk · 24/08/2026
What if we could give people with dementia a 'digital safety net' to help them stay living at home for longer? Minder, our flagship digital care platform, aims to do just that. Read more in @thetimes.com ⬇️ www.thetimes.com/uk/healthcar... @lifearc.bsky.social @imperialmed.bsky.social
thetimes.com
How smart tech could let dementia patients live at home for longer
Equipping houses with sensors and monitors costs less than the monthly cost of a care home. It would also reduce anxiety and relieve pressure on hospitals
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UK Dementia Research Institute @ukdri.ac.uk · 03/08/2026
"The field has completely turned on its head, and now we know inflammation is a huge part of the pathogenesis of Alzheimer's." Prof @tspiresjones.bsky.social (UK DRI at Edinburgh) discusses the complex role of inflammation in Alzheimer's, on BBC's Inside Health ⬇️ www.bbc.co.uk/sounds/play/...
bbc.co.uk
Inside Health - Is inflammation behind all chronic disease? - BBC Sounds
How understanding inflammation could transform treatments from cancer to Alzheimer’s.
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Institute of Psychiatry, Psychology & Neuroscience @kingsioppn.bsky.social · 27/07/2026
How can the brain 🧠 promote healthy ageing? @ulelab.bsky.social at King's and Dr Mathieu Bourdenx (UCL) have been awarded £3.8m by @wellcometrust.bsky.social to study role of interstasis in protecting neurons. www.kcl.ac.uk/news/3.8m-aw... #AgingResearch @ukdri.ac.uk @uclbrainscience.bsky.social
kcl.ac.uk
£3.8m awarded to study protective mechanisms against neuron damage and ageing | King's College London
A new study, co-led by neuroscientists at King’s College London, University College London and the UK Dementia Research Institute (UK DRI), will investigate how neurons can protect themselves from toxic protein accumulation, with implications for neurodegenerative diseases and ageing.
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Dr Jo Jackson @jojacksonhere.bsky.social · 28/07/2026
Glad to see this work finally out! A joy working with the incredible Nurun Fancy to figure out the interaction between TREM2 and CD33, how TREM2 variants differ and what happens to other cell types in cases with TREM2 variants. Thanks to everyone involved in the study, it was a great team effort!
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UK Dementia Research Institute @ukdri.ac.uk · 27/07/2026
How might neurons protect themselves from toxic protein build-up?🧠 @ulelab.bsky.social & @mbourdenx.bsky.social have been awarded £3.8m by @wellcometrust.bsky.social to study role of interstasis in protecting neurons ukdri.ac.uk/news-and-eve... @kingsioppn.bsky.social @uclbrainscience.bsky.social
ukdri.ac.uk
Two UK DRI Group Leaders awarded major Wellcome funding to study protective mechanisms against neuron damage and ageing
A new study, co-led by researchers at the UK DRI at King’s and the UK DRI at UCL will investigate how neurons can protect themselves from toxic protein accumulation, with implications for neurodegener...
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UK Dementia Research Institute @ukdri.ac.uk · 24/07/2026
Could a protective gene counteract risk of Alzheimer's in people with a high-risk gene variant? 🧬 Researchers led by Dr @jojacksonhere.bsky.social revealed how TREM2 – a well-known Alzheimer’s risk gene – interacts with CD33, a gene that can reduce disease risk. ukdri.ac.uk/news-and-eve...
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UK Dementia Research Institute @ukdri.ac.uk · 17/07/2026
What can scientists learn from the brains of centenarians? 🧠 @sj-marzi.bsky.social, Dr Alexi Nott & Prof Henne Holstege investigate what makes some people resilient to dementia into old age, in a major new project 👏 ukdri.ac.uk/news-and-eve... @alzheimersresearchuk.org
ukdri.ac.uk
UK DRI researchers awarded Dementia Frontiers Fund project to study centenarian brains
An international team led by Dr Sarah Marzi (UK DRI at King’s), with Dr Alexi Nott (UK DRI at Imperial) and Professor Henne Holstege (Amsterdam UMC and VIB-KU Leuven Center for Neuroscience) has won £...
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Institute of Psychiatry, Psychology & Neuroscience @kingsioppn.bsky.social · 17/07/2026
What can scientists learn from the 🧠 brains of centenarians 💯? @sj-marzi.bsky.social co-leads team EMERALD — asking what protects some people's brains from #dementia. www.kcl.ac.uk/news/what-ca... @ukdri.ac.uk @imperialcollegeldn.bsky.social @amsterdamumc.bsky.social @alzresearchuk.bsky.social
kcl.ac.uk
What can scientists learn from the brains of centenarians? £1.5m awarded from the Dementia Frontiers Fund | King's College London
Dr Sarah Marzi will co-lead team EMERALD, who have been awarded £1.5m from the Dementia Frontiers Fund to study how some people's brains may be more resiliant to dementia, with the aim to leverage these insights to develop therapeutics.
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Dementia Researcher @dementiaresearcher.bsky.social · 14/07/2026
Join us on 21 July at 2pm to learn about the Race Against Dementia x @ukdri.ac.uk AI Innovation Fellowship Scheme, hear from speakers and get tips on applying. #AI youtube.com/live/1XpA9Sk...
youtube.com
Applying for the RAD X UK DRI AI Innovation Fellowship
YouTube video by Dementia Researcher
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UK Dementia Research Institute @ukdri.ac.uk · 02/07/2026
We're excited to be taking part in the Health Data Research UK (HDR UK) Black Internship Programme for the second year 🎉 A warm welcome to the five students who will be spending time at our centres across the UK, learning new skills and developing their talents.
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UK Dementia Research Institute @ukdri.ac.uk · 01/07/2026
How does the cell's transport network go wrong in neurodegenerative conditions? 🧠 New research led by @avezovlab.bsky.social (UK DRI at @cneurodept.bsky.social ) reveals new insight and a potential therapeutic avenue 👉 ukdri.ac.uk/news-and-eve...
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Institute of Psychiatry, Psychology & Neuroscience @kingsioppn.bsky.social · 25/06/2026
King's researchers identify a new mechanism for neuronal death in #dementia, called karyoptosis, that links the build-up of toxic proteins to neurons dying. @alzheimersresearchuk.org @ukdri.ac.uk @rcasterton.bsky.social
kcl.ac.uk
New mechanism found for neuronal death in Alzheimer's and frontotemporal dementia | King's College London
Markers of a new mechanism for cell death, called karyoptosis, have been found in brains of patients with Alzheimer’s disease and frontotemporal dementia (FTD).
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LifeArc @lifearc.bsky.social · 16/06/2026
Where there’s a common vision, there’s an opportunity for collaboration. The @ukdri.ac.uk shares our ambition to improve tests, treatments and ultimately find cures for people living with motor neuron disease and rare dementias. Learn more: t.ly/snVaa #PartnerForChange
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UK Dementia Research Institute @ukdri.ac.uk · 15/06/2026
Last month we celebrated the official launch of our Parkinson’s Research Centre, in partnership with @parkinsons.org.uk 🎉 📹 Watch the video below to hear Centre Director Prof Miratul Muqit outline his vision for the new centre. ukdri.ac.uk/news-and-eve...
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UK Dementia Research Institute @ukdri.ac.uk · 04/06/2026
Around six million people live with Down syndrome globally, and around 90% will develop Alzheimer’s in midlife. Dr Frances Wiseman & colleagues have developed two new models of Down syndrome related Alzheimer’s, that could enable better study of the condition's impact 👉 ukdri.ac.uk/news-and-eve...
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UK Dementia Research Institute @ukdri.ac.uk · 23/05/2026
Our researchers at the UK DRI at Edinburgh are featured on the BBC today, highlighting how AI is transforming the search for treatments for neurodegenerative conditions 👏 Thank you to Steve, who generously shared his story and why research gives him hope 💙 www.bbc.co.uk/news/article...
bbc.co.uk
AI used to speed up search for motor neurone disease drugs
Researchers hope the work will help identify affordable, effective drugs to treat conditions like MND.
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UK Dementia Research Institute @ukdri.ac.uk · 22/05/2026
This #DementiaActionWeek, we were delighted to welcome @vikkislademp.bsky.social & @alisonebennett.bsky.social to UK DRI at King’s Researchers showcased how they're uncovering new opportunities to diagnose early & slow onset by studying underlying processes & harnessing data science advances.
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Russell Group @russellgroup.bsky.social · 18/05/2026
In #DementiaActionWeek learn how our universities are working with @ukdri.ac.uk to spearhead efforts to diagnose and treat this devastating disease. This includes better testing to enable accessible, accurate and early detection, even before symptoms appear. www.russellgroup.ac.uk/impact/diagn...
russellgroup.ac.uk
Diagnosing dementia: developing blood tests at the UK Dementia Research Institute | Russell Group
Dementia presents a major health challenge in our ageing society. Its personal, societal and economic consequences are devastating. With disease-modifying therapies finally on the horizon, there is re...
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Miron Lab @mironlab.bsky.social · 21/05/2026
🧪I'm deeply honoured to be elected a member of @acmedsci.bsky.social. Very grateful to my wonderful trainees, mentors, collaborators, and colleagues over 22 yrs from @edinunineuro.bsky.social @ukdri.ac.uk @cmvm-edinburghuni.bsky.social @unityhealthto.bsky.social @utoronto.ca @theneuro.bsky.social
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UK Dementia Research Institute @ukdri.ac.uk · 19/05/2026
Only 2% of people with dementia symptoms ever get a specialist diagnostic test We are developing: 🩸 Blood tests to distinguish between conditions ⌚ Smartwatch AI detecting Parkinson's 7 years early 🛏️ Sleep mats predicting tau accumulation www.russellgroup.ac.uk/impact/diagn... #DementiaActionWeek
russellgroup.ac.uk
Diagnosing dementia: developing blood tests at the UK Dementia Research Institute | Russell Group
Dementia presents a major health challenge in our ageing society. Its personal, societal and economic consequences are devastating. With disease-modifying therapies finally on the horizon, there is re...
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Institute of Psychiatry, Psychology & Neuroscience @kingsioppn.bsky.social · 14/05/2026
@sj-marzi.bsky.social has been awarded $1.4m from @asapresearch.parkinsonsroadmap.org as part of a $9m international collaboration investigating how environmental toxicants may influence Parkinson’s disease. www.kcl.ac.uk/news/9m-awar... @ukdri.ac.uk #ParkinsonsResearch
kcl.ac.uk
$9m awarded to uncover how environmental toxicants influence Parkinson's | King's College London
Dr Sarah Marzi receives $1.4m from a Collaborative Research Network grant awarded by Aligning Science Across Parkinson's (ASAP) to study link between toxicants and Parkinson’s disease.
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SPARK NS @sparkns.bsky.social · 08/05/2026
The best reasons to apply to the SPARK NS program don’t come from SPARK NS. Hear below a message from Miratul Muqit, PhD, Professor of Experimental Neurology, University of Dundee, and Director of UK Dementia Research Institute Parkinson’s Research Centre, University of Edinburgh. @ukdri.ac.uk
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UK Glia Network @ukglia.bsky.social · 11/05/2026
From the organising committee, from @edinunineuro.bsky.social, from the @ukdri.ac.uk, the one and only Dr Philip Hasel @philiphasel.bsky.social Registration is closes May 18th: www.physoc.org/events/uk-gl... #neuroscience #careers #networking #UK #science #neuroskyence #glia #Bristol #June
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UK Glia Network @ukglia.bsky.social · 01/05/2026
We are exceptionally proud to announce that the second UK Glia Network meeting will be closed by FRS, Prof Bal Khakh Returning to the UK to join the @ukdri.ac.uk we are super pleased he is coming to Bristol in June You can come too, registration still open: www.physoc.org/events/uk-gl...
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UK Glia Network @ukglia.bsky.social · 06/05/2026
Coming from Edinburgh @edinunineuro.bsky.social and the @ukdri.ac.uk, the ineffable @bdiazcastro.bsky.social #neuroscience #networking #science #career #opportunities #UK #glia Registration closes May 18th: www.physoc.org/events/uk-gl...
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Institute of Psychiatry, Psychology & Neuroscience @kingsioppn.bsky.social · 06/05/2026
Professor Corinne Houart and Dr Richard Taylor (@ukdri.ac.uk at King's) received a new £500k+ grant from @alzresearchuk.bsky.social to study how RNA-binding proteins, which are disrupted in #dementia, might be important for protecting against degeneration. @cohouart.bsky.social
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Dervis Salih @dervissalih1.bsky.social · 06/05/2026
Join us! Research Fellow role at UCL @ukdri.ac.uk @uclqsion.bsky.social with me & @sj-marzi.bsky.social studying oligodendrocytes, genetics & epigenetics in ageing & neurodegeneration using multiomics/bioinformatics. Collaboration with Alexi Nott & @rikeshrajani.bsky.social Closing date: 2nd June
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UK Dementia Research Institute @ukdri.ac.uk · 07/05/2026
💡New evidence about the causes of a common type of stroke offers clues as to why widely used treatments like aspirin may not work. The new study, led by Prof Joanna Wardlaw found that instead of fat build-up, enlargement & widening of arteries may cause lacunar stroke 👉 lnkd.in/e-__v2kK
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UK Dementia Research Institute @ukdri.ac.uk · 01/05/2026
Could we boost the nervous system's ability to repair damaged brain cells?🔬 New research by Dr Jobert Vargas and Prof Giampetro Schiavo (UK DRI at UCL) in collaboration with Dr Andrea Serio (UK DRI at King’s), uncovers key insight into how human neurons can be repaired. ukdri.ac.uk/news-and-eve...
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UK Dementia Research Institute @ukdri.ac.uk · 30/04/2026
Could improving the way we collect & store brain tissue help better preserve it for research? A study by Dr @jojacksonhere.bsky.social & Prof Paul Matthews (UK DRI at Imperial) with researchers at McGill University reveals temperature plays a greater role than previously thought👉 lnkd.in/eG6yqJzD
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UK Dementia Research Institute @ukdri.ac.uk · 24/04/2026
Join the UK DRI's Prof Julie Williams, & neuroscientist & psychologist Dr Sabina Brennan as they share insights from the forefront of dementia research and care. 📍 Cheltenham Science Festival 🗓️ 7 June, 3:15pm www.cheltenhamfestivals.org/events/repai...
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UK Dementia Research Institute @ukdri.ac.uk · 22/04/2026
Listen to the third Between the Signals podcast episode: "Could a One-Time Brain Injection Replace a Lifetime of Medication? Gene Therapy Explained” Dr Sarah Mizielinska speaks with expert Professor Chris Shaw to understand how fundamental research gets turned into medicine. youtu.be/USGnc2yHhXQ
youtu.be
Between the Signals: Could a One-Time Brain Injection Replace a Lifetime of Medication?
YouTube video by UK Dementia Research Institute - UK DRI
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UK Dementia Research Institute @ukdri.ac.uk · 15/04/2026
Congratulations to Dr Samuel Barnes (UK DRI at Imperial) & team at @imperialcollegeldn.bsky.social , who have been awarded major @wellcometrust.bsky.social funding to develop a next generation imaging system 👏 Read the full story 👉 lnkd.in/eq7FudUE
Graphic containing a headshot of Samuel Barnes, and text that reads: 
Congratulations to Dr Samuel Barnes
Dr Samuel Barnes (UK DRI at Imperial) and a team of researchers at Imperial College London, led by Dr Amanda Foust, have been awarded £3.92M by Wellcome to develop a new kind of high-throughput, real-time, volumetric voltage and hemodynamic imaging system based on light-field microscopy (LFM).
Dr Barnes will use the new technology to investigate how problems with the brain’s neurovascular system might contribute to Alzheimer's, and whether electrically stimulating specific brain circuits could help to treat it.
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UK Dementia Research Institute @ukdri.ac.uk · 14/04/2026
Congratulations to UK DRI Group Leader Dr Mootaz Salman on this award! 👏 ukdri.ac.uk/news-and-eve...
ukdri.ac.uk
Dr Mootaz Salman awarded Biochemical Society Inspiration and Resilience Award
We are delighted to announce that UK DRI Group Leader Dr Mootaz Salman has been awarded the Biochemical Society Inspiration and Resilience Award, recognising both his scientific contributions and his ...
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Isabel N Christie PhD @izzynchristie.bsky.social · 14/04/2026
Wish I could do this PhD with Bal Khahk 😍 Newly appointed Fellow of the Royal Society, he is one of the best scientists to work with right now and joining the @ukdri.ac.uk in @cardiffuni.bsky.social #neuroskyence #opportunities #careers #PhD #glia # www.findaphd.com/phds/project...
findaphd.com
Astrocyte-Neuron Interactions in Neural Circuit Function and Dementia at Cardiff University on FindAPhD.com
PhD Project - Astrocyte-Neuron Interactions in Neural Circuit Function and Dementia at Cardiff University, listed on FindAPhD.com
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UK Dementia Research Institute @ukdri.ac.uk · 08/04/2026
⭐️ Group Leader job opportunity ⭐️ We're currently recruiting for two Group Leader positions within our centre at Cardiff University. Full information and to apply 👉️ buff.ly/JFbUtci
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UK Dementia Research Institute @ukdri.ac.uk · 07/04/2026
🧠 The Dementia Trials Accelerator (DTA) is now underway! Led by the UK DRI & Health Data Research UK (HDR UK), it aims to tackle one of dementia research's biggest challenges: recruiting enough participants for clinical trials. The first participants have now been welcomed into clinics 👏
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UK Dementia Research Institute @ukdri.ac.uk · 30/03/2026
New research sheds light on why Alzheimer's treatments targeting amyloid alone may not be enough 🧠 Prof @marcaurelbusche.bsky.social & Dr Robert Ellingford suggest the hallmark proteins amyloid beta and tau may work together to disrupt memory circuits 👉 ukdri.ac.uk/news-and-eve...
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Dementia Researcher @dementiaresearcher.bsky.social · 25/03/2026
Research Assistant Vacancy at @ukdri.ac.uk Cambridge analysing RNA sequencing data to study RNA processing in Parkinson’s and neurodegeneration using computational approaches. Closing date: 6th April www.dementiaresearcher.nihr.ac.uk/job/research...
dementiaresearcher.nihr.ac.uk
Research Assistant: Analysis of Transcriptomic Datasets
Research Assistant at UK DRI Cambridge analysing RNA sequencing data to study RNA processing in Parkinson’s and neurodegeneration using computational approaches
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UK Dementia Research Institute @ukdri.ac.uk · 23/03/2026
We're excited to launch a new 4-year PhD studentship programme funded by @thebhf.bsky.social! 🙌 The programme will support up to 10 students across 2 intakes, investigating vascular mechanisms underlying dementia and neurodegeneration. ukdri.ac.uk/news-and-eve...
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Isabel N Christie PhD @izzynchristie.bsky.social · 23/03/2026
Late breaking abstracts- posters only! Don't miss the opportunity to see the mighty Bal Khakh FRS He is entertaining, British and returning to the UK to bring his brilliance to the @ukdri.ac.uk #neuroscience #glia #astroctyes #microglia #oligodendrocytes #myelin www.physoc.org/events/uk-gl...
physoc.org
UK Glia 2026
UK Glia 2026 meeting will highlight the pivotal role of glia in brain physiology, offering invaluable insights for those investigating glia function in both health and disease. Find out more about the...
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UCL Faculty of Brain Sciences @uclbrainscience.bsky.social · 17/03/2026
On day two of #BrainAwarenessWeek, Professor Nick Fox reflects on the discoveries and unexpected moments that defined his career in dementia research. Read more 👇 www.ucl.ac.uk/brain-scienc... @uclqsion.bsky.social @ukdri.ac.uk
Reads: Looking back over your career, what do you consider to be your biggest breakthrough?

"During my PhD, I discovered that subtracting one brain scan from another revealed tiny changes over time, a method that shaped my career and showed that Alzheimer’s begins years before symptoms." Professor Nick Fox
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Dementia Researcher @dementiaresearcher.bsky.social · 12/03/2026
Research Fellow role at the UK Dementia Research Institute at UCL studying gut brain immune mechanisms in Parkinson disease and synuclein related neurodegeneration. @ukdri.ac.uk www.dementiaresearcher.nihr.ac.uk/job/research...
dementiaresearcher.nihr.ac.uk
Research Fellow: Neuroimmune interactions along the gut–brain axis
UK Dementia Research Institute at UCL seeks Research Fellow to study gut brain immune interactions in Parkinson disease and synuclein related neurodegeneration.
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UK Dementia Research Institute @ukdri.ac.uk · 16/03/2026
Heading to Copenhagen for AD/PD this week? ✈️ Don't miss talks from the UK DRI's Dr Martha Foiani (Duff Lab, UK DRI at UCL) & Dr Cynthia Sandor (UK DRI at Imperial) tomorrow ⬇️ Keep an eye on our feed throughout the week as we highlight more UK DRI researchers taking to the stage at #ADPD2026 👏
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UK Dementia Research Institute @ukdri.ac.uk · 05/03/2026
Congratulations to Dr Maura Malpetti, Prof @tspiresjones.bsky.social & Dr Robert McGeachan, who were awarded prizes at @alzheimersresearchuk.org's conference last week! 👏 www.ukdri.ac.uk/news-and-eve...
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