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Wendy Xin

@droligo.bsky.social
862 followers 331 following 82 posts

🇨🇦 Scientist and Assistant Professor at UHN/University of Toronto · oligodendrocytes & myelin | synapses & circuits | neurodevelopment · BSc UofT -> PhD Johns Hopkins -> Postdoc UCSF · she/her www.oligodendrocyte.org

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Reposted by Wendy Xin
W. Brent Derry @wbderry.bsky.social · 11h
Faculty position at the University of Toronto 👇 jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca
Assistant Professor - Systems Neurophysiology
Assistant Professor - Systems Neurophysiology
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Denise J. Cai, Ph.D. @denisejcai.bsky.social · 9h
NEW: The anterior hypothalamic nucleus acts like a volume knob for stress, scaling the brain’s response to threatening events 🧠 Read the Cai Lab's latest paper, led by @zachtpennington.bsky.social, in @nature.com 🎉 www.nature.com/articles/s41... More: bsky.app/profile/did:...
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Ciaran Murphy-Royal @murphyroyallab.org · 25/09/2026
Come join us at the @crchum.bsky.social ! It really is as good as it looks!
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Jibran Khokhar @drjkhokhar.bsky.social · 16/09/2026
So grateful to @thetransmitter.bsky.social for the opportunity to talk about a paper that truly shaped how I think about my science by @fowleruci.bsky.social and @paulkennyphd.bsky.social! They helped make causal sense of the association that people call “Mr. Big“ in the context of 🚬!
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Keri Martinowich @martinowk.bsky.social · 13/09/2026
Epinephrine producing neurons in the locus coeruleus (LC) are among the earliest cells affected in Alzheimer’s disease, and yet we know remarkably little about their molecular biology in human 🧠, in part due to technical challenges because the LC is tiny and really difficult to profile.
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Jeremiah Cohen @jeremiahycohen.bsky.social · 16/09/2026
Happy to share the version of record of our locus coeruleus paper here: www.nature.com/articles/s41... Prior thread on some of our discoveries in this study: bsky.app/profile/jere...
nature.com
Topographic structure and function of locus coeruleus noradrenaline neurons - Nature
Dorsal and ventral noradrenergic neurons in the locus coeruleus form topographic subpopulations whose projection patterns and activity encode choice switching, reward-prediction errors and disregard o...
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Steve Ramirez @okaysteve.bsky.social · 16/09/2026
🚨 new work from the lab! "Hippocampal astrocytic sequences emerge during learning and memory recall" by @ryguy.io & @rsuthard.bsky.social thank you to the entire team for your camaraderie and for muscling through science together 🧠 -- we welcome all feedback! nature.com/articles/s41...
nature.com
Hippocampal astrocytic sequences emerge during learning and memory recall
Nature Neuroscience - Senne, Suthard and colleagues show that dorsal hippocampal astrocytes display time-compressed calcium-event sequences after foot shock and upon context re-exposure, and that...
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Krissy Lyon @krissylyon.bsky.social · 15/09/2026
Super excited to share that I will start my lab at University of Oregon in Fall 2027! We will study astrocyte-neuron interactions in neurodevelopment and related disorders. Grateful to all my mentors and colleagues! I couldn’t be happier to return to the PNW! ion.uoregon.edu/research/fac...
ion.uoregon.edu
Faculty Page
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Lydia Daboussi @daboussi.bsky.social · 03/09/2026
📢Open-rank tenure track faculty position in the Department of Neurobiology at UCLA!!✨🧪
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Ariel Levine @ariellevine.bsky.social · 21/08/2026
Job descriptions for 2 new postdocs positions to study the spinal cord basis of motor control (Just looking at the letterhead for the new lab location has me so excited. Krembil Brain Institute, University Health Network, U. Of Toronto 🇨🇦, here we come!) @kbi-uhn.bsky.social @uhnresearch.ca
Postdoc Job Advert for a position studying the cell type and circuit mechanisms of spinal motor controlPostdoc Job Advert for a position studying the neural activity underlying spinal motor control
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Jess Cardin @jess-cardin.bsky.social · 18/08/2026
Yale Neuroscience 🧠 @yaleneuro.bsky.social is hiring this year! We have 2 searches, one cell/molecular/systems neuro (apply.interfolio.com/190736) and one computational neuro (apply.interfolio.com/190740). Got questions about the searches, the department, or the process? Please ask, happy to chat!
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Miron Lab @mironlab.bsky.social · 12/08/2026
👋MS community: We are hosting an event for people with MS, their families, carers & the community! Hear from scientists on how fundamental research in MS has driven discoveries and evolved significantly over the years & have a chance to ask us your Qs. Oct20 4-6PM, sign up here: lnkd.in/gpr4MKux
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UM-MIND - Institute for Neuroscience Discovery @um-mind.bsky.social · 18/08/2026
UM-MIND is hiring! We are recruiting several tenure-track neuroscience faculty members, preferably at the Assistant Professor level, to join our institute at the University of Maryland School of Medicine here in Baltimore, MD. Learn more here: umb.taleo.net/careersectio... @medschool.umaryland.edu
umb.taleo.net
Assistant Professor, University of Maryland – Medicine Institute for Neuroscience Discovery (UM-MIND)
Click the link provided to see the complete job description.
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The Transmitter @thetransmitter.bsky.social · 18/08/2026
In this month’s “Liftoff,” our Q&A series with PIs who opened new labs, @jhennig.bsky.social discusses fostering a culture of polite and constructive disagreement and @droligo.bsky.social talks about the value of being kind. By @franciscorr25.bsky.social www.thetransmitter.org/liftoff-new-...
thetransmitter.org
Liftoff: New lab alerts
Learn about early-career scientists starting their own labs.
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Keri Martinowich @martinowk.bsky.social · 12/08/2026
With expansion of several stem cell based initiatives @lieberinstitute.bsky.social - we are hiring! We are looking for a Staff Scientist with expertise in hiPSCs and iPSC-derived neuronal models to join our Stem Cell Core, directed by @tsawada1.bsky.social recruiting.paylocity.com/recruiting/j...
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Anthony Ramnauth @philoneurosci.bsky.social · 05/08/2026
This seems super important for in vivo experiments #Norepinephrine and #dopamine #sensor crosstalk depends on local innervation density doi.org/10.1038/s415...
doi.org
Norepinephrine and dopamine sensor crosstalk depends on local innervation density - Nature Neuroscience
This study shows that GPCR-based norepinephrine and dopamine sensors display crosstalk in several brain areas. Relative innervation densities determine the extent of crosstalk, and loss-of-function co...
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Travis Faust @travisfaust.bsky.social · 03/08/2026
Do psychiatric symptoms in epilepsy always arise from seizures? In ALDH7A1 models, seizure risk traced to the liver; mood-related behavior to astrocytes. One gene. Two tissues. Two pathophysiologies. Neither begins in neurons. New in Science Advances: doi.org/10.1126/scia... 1/11
doi.org
Astrocyte redox imbalance underlies prelimbic neuronal hypoactivity and maladaptive affective behaviors in epilepsy
Astrocyte antioxidant imbalance reduces neuronal activity, driving depression-like behavior in epilepsy dissociable from seizures.
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Rafael Almeida @almeidalab.bsky.social · 25/07/2026
New preprint from the lab 🥳 We made new knock-in zebrafish 🐟 that fluorescently tag endogenous neurofascins. So now, we can live-image neuronal nfasca/NF186 and glial nfascb/NF155 non-invasively, as nerves, nodes of Ranvier and paranodes develop in vivo 🧵👇 www.biorxiv.org/content/10.6...
biorxiv.org
Live-imaging of endogenous neurofascins reveals glial adhesion shapes developing nodes of Ranvier
The organisation of myelinated axons into specialised domains is essential for saltatory conduction and depends on the polarised distribution of neuronal and glial cell-adhesion molecules, including n...
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Krembil Brain Institute 🧠 @kbi-uhn.bsky.social · 20/07/2026
🎉 Please join us in welcoming Dr. Richard Roth to UHN’s @krembilresearch! Dr. Roth joins us as a Scientist, focusing on the interplay between synaptic plasticity and neural circuit adaptation, and how these processes shape motor learning.    🔗 Learn more about his research: www.motor-plasticity.org
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MariaEichelVogel.bsky.social @mariaeichelvogel.bsky.social · 19/07/2026
Excited to share my postdoc paper from the @lyons-lab.bsky.social Our question: what controls axon diameter? It varies >100-fold between neurons, shapes signal speed & myelination, and changes in disease. Yet very little is known about what regulates it. 🧵 journals.plos.org/plosbiology/...
journals.plos.org
A high-resolution phenotypic screen identifies regulators of CNS axon diameter in zebrafish
Axon diameter is important for action potential conduction speed, but what molecular pathways influence this neuronal property? This study reports a high-resolution imaging-based chemical screening pi...
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Wendy Xin @droligo.bsky.social · 17/07/2026
Excited to get started!
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Wendy Xin @droligo.bsky.social · 16/07/2026
Did I even leave California
Toronto skyline in a haze of smoke
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Wendy Xin @droligo.bsky.social · 08/07/2026
Our review on glial orchestration of neurodevelopment is online at @cp-devcell.bsky.social! Great fun working with Krissy Sakers and Pat Sheehan from the Eroglu and Schafer labs, and special thanks to first author Krissy for her tremendous work bringing this to fruition! www.cell.com/developmenta...
cell.com
Glia orchestrate neural circuit development
In this review, Sakers et al. discuss how astrocytes, microglia, and oligodendrocyte lineage cells actively regulate neural circuit formation, refinement, and stabilization. They propose that coordina...
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Leading Edge Fellows Program @leadingedgeprogram.bsky.social · 09/06/2026
We are thrilled to announce the 2026 Zara Weinberg Leading Edge Fellows! 40 remarkable postdocs pursuing transformative research in biological/biomedical sciences. This is the 7th Leading Edge cohort and we are so excited to welcome them! www.leadingedgesymposium.org/fellows/
Congratulations to the 2026 Zara Weinberg Leading Edge Fellows! 
Airi Yoshimoto, Yijun Yang, Alexandra Wells, Simran Virdi, Archana Venkataraman, Emery Usher, Marianna Tannus Ruckert, Wenzhi Song, Kathryn Shelley, Selin Schamiloglu, Julia Peloggia de Castro, Ines Patop, Ruhi Patel, Suranjana Pal, Bernie Simone Owusu Yaw, LaShae Nicholson, Sivapratha Nagappan Chettiar, Dallas Mould, Jessica Moore, Deka Mohamed, Sierra Marable, Annie Ly, Xi (Lucy) Lu, Deirdre Logsdon, Anna Lipkin, Ellen Lesser, Mia Konjikusic, Veronika Kondev, Cayla Jewett, Lucia Ichino, Erin Huiting, Maggie Horst, Isabella Gaeta, Martha Echevarria-Andino, Natasha Claxton, Sarah Cherkaoui, Nikita Bhalerao, Merci Best, Meenakshi Asokan, Alicer Andrew
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The Picower Institute for Learning and Memory at MIT @picowerinstitute.bsky.social · 26/05/2026
Myriam Heiman named the director of The Picower Institute for Learning and Memory. Heiman, who studies neurodegenerative diseases such as Huntington’s disease and Parkinson’s disease, will lead the institute beginning July 1. picower.mit.edu/news/myriam-... #neuroscience
Myriam Heiman stands along blue glass windows in MIT's Building 46
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studioosynapse @studioosynapse.bsky.social · 25/05/2026
hippocampus brain section keychain? yes please🙂‍↕️
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Michael Williamson @m-r-williamson.bsky.social · 19/05/2026
Thrilled to share that I’ll be starting my lab at the SickKids Research Institute and University of Toronto in August! williamsonlab.ca Recruiting at all levels. Get in touch if you’re interested in astrocyte biology of cognition and disease!
williamsonlab.ca
Williamson Lab
The Williamson Lab studies astrocyte biology across development, cognition, and disease.
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Keri Martinowich @martinowk.bsky.social · 22/05/2026
We updated our preprint, "Mapping spatially organized molecular and genetic signatures of schizophrenia across multiple scales in human prefrontal cortex" to now include spatial eQTL and genetic colocalization analyses: www.biorxiv.org/content/10.6...
Colored plots reflecting spatial transcriptomics data in human cortex tissue that represent cortical laminae
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SJo @sjo09.bsky.social · 13/05/2026
New paper from the lab. Using longitudinal ca imaging, activity-dependent tagging and optogenetics, we show that newly allocated fear engram neurons in amygdala undergo a brief period of coordinated “offline reverberation” immediately after learning. www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Jess Cardin @jess-cardin.bsky.social · 13/05/2026
Do brain circuits really sit in a 'soup' of neuromodulators? Are neurons like soggy bits of bread soaked in signaling factors? Is the whole brain just squelching around in one big pool of warm modulators?
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Zach Pennington @zachtpennington.bsky.social · 13/05/2026
Woo!!!!!! PenningtonLab.com is live!
penningtonlab.com
Pennington Lab
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ACNP @acnporg.bsky.social · 07/05/2026
Deadline fast approaching! ACNP Travel Award Applications are open for the ACNP 65th Annual Meeting: January 10-13, 2027, San Diego, California. Deadline to Submit is May 14, 2026, at 5:00 pm Central. tinyurl.com/5bzaz8va #ACNP2027 #travelawards
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Jeremy Day @daylab.bsky.social · 24/04/2026
New preprint led by recent PhD graduate Dalton Fitzgerald characterizing two distinct populations of VTA dopamine neurons that differ in ion channel expression, intrinsic excitability, and response to drugs of abuse. www.biorxiv.org/content/10.6...
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Myelin Lab @myelinlab.bsky.social · 25/04/2026
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Miguel Á. Luján @lujanma.bsky.social · 22/04/2026
Happy to share my postdoc paper with @joeycheers.bsky.social & collaborators! Building on the work of many former lab members, we describe a VP-VTA projection modulated by endocannabinoids that guides action selection informed by learned cues: www.cell.com/cell-reports...
cell.com
Midbrain endocannabinoids actuate dopamine-based action selection
Dopamine signals guide adaptive responses to reward- and threat-predictive cues, yet the mechanisms shaping these rapid dynamics remain unclear. Luján et al. identify midbrain endocannabinoid signalin...
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Ariel Levine @ariellevine.bsky.social · 21/04/2026
📣 Exciting news: my lab is moving to the Krembil Institute at the University of Toronto’s University Health Network in Fall 2026. We’ll be recruiting for all roles, so reach out if you’re interesting in joining us to study spinal circuits for sensorimotor control www.levine-lab.org
levine-lab.org
Home | Levine Lab
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SJo @sjo09.bsky.social · 20/04/2026
Excited to share our latest in @currentbiology.bsky.social (they who publish the coolest papers!) Memories are encoded by sparse neuronal ensembles (engrams). But most evidence comes from "simple" associative learning tasks. What about more integrative memories like spatial navigation?
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Wendy Xin @droligo.bsky.social · 17/04/2026
#neuroskyence Help! Anyone know of a freezing stage microtome that is still in production? Leica and Epredia have both inexplicably discontinued their models 😢
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Caroline Menard @caromenard666.bsky.social · 17/04/2026
Excited to share the latest one from the lab led by José Solano @jolusolo.bsky.social who explored how early life #stress impacts the mouse 🐭 brain 🧠 vasculature Science 🧪🔬 can be surprising & 2x stress can induce beneficial adaptations leading to resilience, phew! www.biorxiv.org/content/10.6...
biorxiv.org
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Jeremiah Cohen @jeremiahycohen.bsky.social · 13/04/2026
Delighted to share our discoveries about one of the brain's neurotransmitter systems: www.biorxiv.org/content/10.6... Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1
biorxiv.org
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Djavad Mowafaghian Centre for Brain Health (DMCBH) @dmcbrainhealth.bsky.social · 24/03/2026
Meet @zachtpennington.bsky.social, a new researcher at the DMCBH and @psych.ubc.ca who is exploring how the brain regulates stress and emotion. He is also an advocate of building open-source tools to make science more accessible for all. Read more: www.centreforbrainhealth.ca/news/from-sk...
centreforbrainhealth.ca
From skateparks to synapses: Meet Dr. Zach Pennington - Djavad Mowafaghian Centre for Brain Health | DMCBH
When Dr. Zach Pennington was growing up, he never imagined he would become a scientist. “I wanted to be a professional skateboarder, a guitarist in a punk
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lyons-lab.bsky.social @lyons-lab.bsky.social · 02/04/2026
Latest offering. How myelin ensheathes axons! Born from chat with Dwight Bergles on "weird things" we saw oligodendrocytes do, like making "bridges" between sheaths. Driven forward by Cody Call, Kelly Monk, and myelin folks @edinburgh-uni.bsky.social Enjoy! www.nature.com/articles/s41...
nature.com
Flexible ensheathment of axons enables myelination of complex CNS networks - Nature
The rate of axon ensheathment varies within individual myelinating processes, resulting in chains of myelin sheaths connected by bridges consisting of thin cytoplasmic processes that provide&nbsp...
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Ciaran Murphy-Royal @murphyroyallab.org · 24/03/2026
Incredibly proud of this paper led by @ossamaghenissa.bsky.social and @mathiasgua.bsky.social titled Basolateral 'Amygdala Astrocytes Encode Anxiety States'. www.cell.com/neuron/fullt... 🧵 below
cell.com
Basolateral amygdala astrocytes encode anxiety states
Ghenissa et al. provide evidence that basolateral amygdala astrocytes reliably encode anxiety states. Using simultaneous in vivo calcium recordings across an array of behavioral tasks, combined with g...
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mark cembrowski @markcembrowski.bsky.social · 16/03/2026
Registration for the @canacn.bsky.social 2026 Neural Circuits and Behaviour satellite meeting is now live! Looking forward to hosting this event with @franklandlab.bsky.social again, and we're looking to have 4 trainee talks as part of the satellite. Register at www.eventbrite.com/e/1984146883...
eventbrite.com
Neural Circuits and Behaviour CAN 2026 Satellite Meeting
The third-annual CAN satellite event, bringing together Canadian neuroscientists studying circuits and behaviour.
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Richard Roth @rhroth.bsky.social · 13/03/2026
Very excited to share that I’m starting my lab at the Krembil Brain Institute @kbi-uhn.bsky.social at UHN and the University of Toronto! If you’re interested in motor learning and circuit plasticity, please reach out - we are hiring! www.motor-plasticity.org 1/
motor-plasticity.org
Roth Lab
Welcome! We study the synaptic and circuit bases for motor control and motor learning. The brain’s ability to learn and form new memories relies on the precise reorganization of neuronal circuits, inv...
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Wendy Xin @droligo.bsky.social · 13/03/2026
Super stoked to share that I’m starting my lab at UHN @dkjei-uhn.bsky.social / @kbi-uhn.bsky.social and the University of Toronto! If you’re interested in neuron-myelin interactions in circuit maturation and cognition, please reach out - we are hiring! www.oligodendrocyte.org 1/
oligodendrocyte.org
Xin Lab
Welcome! We study the cellular interactions between neurons and oligodendrocytes, which produce myelin in the central nervous system. Myelination - the process by which oligodendrocytes ensheath neuro...
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allen institute @alleninstitute.org · 09/03/2026
Applications are open for our Next Generation Leaders program! Our NGL program recognizes emerging scientific leaders and invites them into a supportive network. 🔗 Apply by March 31: alleninstitute.org/about/people/nex…
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Michel Cayouette @michelcayouette.bsky.social · 04/02/2026
Happy to announce that our latest paper is now out! Have you ever wondered how neural tissues control their size? In this paper, we show that cell division orientation is critical in both the cortex and retina. www.science.org/doi/10.1126/...
science.org
Oriented cell divisions induce basal progenitors and regulate neural expansion across tissues and species
A fundamental role for division orientation in progenitor output driving cortical and retinal growth is revealed.
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Robert Hill @bobalhill.bsky.social · 23/01/2026
New preprint from Xhoela Bame et al shows that dying oligodendrocytes stick around for weeks to months without mitochondria! This happens after single cell DNA damage or when mitochondrial Fis1 is deleted in oligodendrocytes. www.biorxiv.org/content/10.6...
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Caroline Menard @caromenard666.bsky.social · 16/01/2026
Super excited to share this new paper led by @sejpaton.bsky.social that I briefly mentioned at #ACNP2026 yesterday! 🧪🧠🤓 We tested preventive strategies to protect the brain vasculature #BBB during stress exposure, mix of mouse 🐭 and human data So proud of my team 🤘 www.nature.com/articles/s41...
nature.com
Environmental enrichment and physical exercise prevent stress-induced social avoidance and blood-brain barrier alterations via Fgf2 - Nature Communications
Chronic stress disrupts the brain vasculature and contributes to mood disorders, but mechanisms of resilience remain unclear. Here, the authors show that enriched environments increase astrocytic Fgf2...
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