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Oligodendrocyte lineage cells (OLCs), comprising oligodendrocyte precursor cells (OPCs) and oligodendrocytes, are pivotal in sculpting central nervous system (CNS) architecture and function. OPCs matu...

A stereotaxic atlas of the whole mouse brain, based on a Nissl-stained cytoarchitecture dataset with isotropic 1-μm resolution, achieved through continuous micro-optical sectioning tomography, promises to be a versatile brainsmatics tool for studying the whole brain at single-cell level.

Glia is the top neurobiology journal for research into glial cells (also called gliocytes or neuroglia). Articles cover all aspects of glial cell biology in health and disease.

On June 14—Flag Day—Donald Trump wants tanks in the street and a made-for-TV display of dominance for his birthday. A spectacle meant to look like strength. But real power isn’t staged in Washington. ...

Researchers reveal when boys pull ahead of girls in mathematics, sounding an alarm and providing both an opportunity for schools, parents and researchers.

The interstitial space is a crucial fluid media which links neural and glial cells to communicate each other concentration signals, which are essential for h...

Barbay et al. demonstrate that targeting astrocytes can help reduce spasticity following spinal cord injury. They show that enhancing astrocytic Kir4.1 cha

The function of immune pathways in homeostatic neurobiology remains underexplored. Zengeler et al. find that the inflammasome complex, typically associated with immune responses, is involved in memory...

Universities must be frank about barriers to equity, devise clear metrics for what they are trying to achieve and measure progress transparently.

Synapses on different dendritic domains store distinct types of information

Nature Reviews Neurology, Published online: 04 April 2025; doi:10.1038/s41582-025-01081-yAutoimmunity in multiple sclerosis (MS) is generally considered to be directed against components of myelin or oligodendrocytes. However, this Perspective argues that an immune attack on the ion and water homeostasis machinery in astrocytic endfeet is the primary event in MS and that myelin damage results from astrocyte dysfunction.

"I know that I am making the right decision because whenever I think about changing my gender role, I am flooded with feelings of relief."

Neurodegenerative disorders are commonly associated with autonomic dysfunction as well as the more well-known cognitive and motor effects. In this Review, Mather describes how properties of neurons in...

The ratio between the levels of two synaptic proteins in cerebrospinal fluid predicts future cognitive resilience versus decline among presymptomatic individuals and individuals with early Alzheimer’s...

Stand Up for Science rallies will sweep major cities all across the country today, including in San Francisco's Civic Center.

The link between neuroinflammation and the progression of multiple sclerosis (MS) is unclear. Here, the authors show that in MS lesions, neuronal somatic mutations accumulate 2.5 times faster than in ...

Inferring cellular and molecular dynamics of multiple sclerosis (MS) lesions from postmortem tissue collected decades after onset is challenging. Using magnetic resonance image (MRI)–guided spatiotemp...

Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sens...

A review of studies on communication between the nervous and immune systems redefines the neuroimmune connectome with a focus on health and disease, and discusses how the latest techniques can advance...

Glial cells were first defined by Rudolf Virchow in 1856. About 40 years later, glial research had developed into a field distinct from the mainstream study of neurons as the central elements governi...

Amygdala astrocytes play a critical role in mediating the effects of stress during infancy on neuronal excitability, synaptic plasticity, and memory.

To regulate brain function, peripheral compounds must traverse the blood–brain barrier (BBB), an interface between the brain and the circulatory sy...

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PhD Project - (VIDA DTC) Role of arterial smooth muscle and pericyte dysfunction towards brain waste clearance in Alzheimer’s Disease at The University of Manchester, listed on FindAPhD.com

The diverse roles of astrocytes and their cell-cell interactions in neurologic diseases offer opportunities for their therapeutic targeting.

Astrocytes are a type of glial cell that are involved in actively modulating synaptic plasticity, neurotransmitter homeostasis, and neuroinflammatory responses. More importantly, they coordinate neuro...