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Isabel N Christie PhD

@izzynchristie.bsky.social
482 followers 536 following 289 posts

Neuroscience I Glia I Imaging I Steminist Wellcome Trust Career Development Researcher izzynchristie.wordpress.com UK Glia Network co-founder University of Sheffield

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Reposted by Isabel N Christie PhD
Michael Okun @michael-okun.bsky.social · 30/09/2026
A project that I've been working on for the last couple of years (on & off), dealing with the question of how firing rates of neuronal populations change (1/6).
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Ciaran Murphy-Royal @murphyroyallab.org · 25/09/2026
Come join us at the @crchum.bsky.social ! It really is as good as it looks!
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Reposted by Isabel N Christie PhD
Emily Atkin @emorwee.bsky.social · 17/09/2026
A few weekends ago I went to Miami and attended 9 open houses in extremely high-risk flood areas to see what agents are telling prospective buyers about them. Here is my journey
heated.world
The open houses at the edge of disaster
What are buyers being told about climate risk in Miami? I posed as one to find out.
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Sylvain Baillet @sylvainbaillet.bsky.social · 25/09/2026
👉 Tenure-track opening in neuroscience @crchum.bsky.social @umontreal.ca crchum.carrieresante.gouv.qc.ca/poste/profes...
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Dementia Researcher @dementiaresearcher.bsky.social · 24/09/2026
Competition-funded Cambridge PhD with Dr Malpetti using blood and CSF biomarkers to map inflammation in frontotemporal dementia and predict disease progression. Closing date: 8th December www.dementiaresearcher.nihr.ac.uk/job/phd-flui...
dementiaresearcher.nihr.ac.uk
PhD: Fluid Biomarkers of Inflammation in Frontotemporal Dementia
Competition-funded Cambridge PhD with Dr Malpetti using blood and CSF biomarkers to map inflammation in frontotemporal dementia and predict disease progression.
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Reposted by Isabel N Christie PhD
Guardian US @us.theguardian.com · 23/09/2026
"If a resurgent movement demands action, we finally have the tools to make that demand matter – a working planet that runs mostly on sun and wind is in tantalizing reach," writes @billmckibben.bsky.social. "At the last possible moment, with backs to the wall, we still have our face to the sun."
theguardian.com
The climate fight has one great ally. You just can’t look at it directly | Bill McKibben
There is hope in solar power. As the UN meets, we are urging leaders to pursue a clear goal: clean energy for all by 2030
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Reposted by Isabel N Christie PhD
Dementia Researcher @dementiaresearcher.bsky.social · 23/09/2026
The Srinivasan Lab is looking for a Postdoctoral Scientist to work out how lymphatic vessels and heart valves develop, and what goes wrong in disease. The work uses mouse models, imaging and spatial transcriptomics. www.dementiaresearcher.nihr.ac.uk/job/postdoc-...
dementiaresearcher.nihr.ac.uk
Postdoc Scientist: Lymphatic and Cardiovascular Valve Biology
Postdoc at OMRF's Srinivasan Lab studying how lymphatic vessels and heart valves develop and fail, using mouse models, imaging and spatial transcriptomics.
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Reposted by Isabel N Christie PhD
Waggoner Lab @labwaggoner.bsky.social · 21/09/2026
Review @cellcellpress.bsky.social Oligodendrocytes in central nervous system health and disease www.cell.com/cell/fulltex...
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 21/09/2026
MALDI-TOF imaging mass spectrometry demonstrates sex- and age-dependent spatial changes in brain energy metabolism in response to amyloid stress using a mouse model of Alzheimers Disease www.biorxiv.org/content/10.64898/20…
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 18/09/2026
Perivascular fibroblasts locally regulate the vasomotor dynamics of pial arterioles www.biorxiv.org/content/10.64898/20…
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Reposted by Isabel N Christie PhD
LifeCanvas Technologies @lifecanvastech.bsky.social · 18/09/2026
Scientists at the @alleninstitute.org have made major strides in understanding one of the brain’s key neuromodulatory systems. Read on to learn more and check out the open access paper... 🧵 (1/5)
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Prof Jenny Rohn @jennyrohn.bsky.social · 04/09/2026
Thrilled our latest paper out @natureportfolio.nature.com Nature Comms, lead author @microberamon.bsky.social, who developed P-FLO, a urine-flowing human micro-bladder model in collab with Oxford & Leicester to understand #UTI biology & treatment failure 1/4 #UTISky www.nature.com/articles/s41...
nature.com
Effect of human urinary microenvironment and fluid flow on antibiotic and phage therapy efficacy against uropathogenic Escherichia coli - Nature Communications
Maset et al. show that bladder conditions strongly influence how urinary tract infections respond to antibiotics and bacteriophages, highlighting the need for more realistic lab models to improve diag...
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Science News @scinews.bsky.social · 15/09/2026
Obesity impairs neuronal, microglial, metabolic and cerebrovascular function in the hippocampus, prefrontal cortex, white matter and other regions that are crucial for cognition, mirroring changes observed in ageing and dementia. www.nature.com/articles/s41...
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allen institute @alleninstitute.org · 14/09/2026
Open science means data, software, lab protocols, cell lines, and even custom microscope designs freely available to everyone, so researchers can build on each other's work instead of starting from scratch. More collaboration = faster discoveries.
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allen institute @alleninstitute.org · 14/09/2026
It's #OpenScienceWeek! Research can be expensive, competitive, and surprisingly hard to share. Paywalls, data barriers, and the race to publish have historically kept discoveries locked away. Open science is the movement to change that.
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Eliezyer de Oliveira @eliezyer.bsky.social · 14/09/2026
After a long journey through review, our paper is finally out in Nature Communications. We started with a simple problem: The visual cortex is strongly modulated by movement. So how can it represent the visual world without movement interfering with everything? www.nature.com/articles/s41...
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Science Magazine @science.org · 14/09/2026
Increasing the breadth of researchers trained as reviewers is crucial. In 2024, we began a program that invites reviewers to add trainees as co-reviewers. Nearly 6000 scientists have participated. All our reviewers, past and present, can now get credit on ORCID. #PeerReviewWeek
Science thanks each of our reviewers for their critical contribution. #PeerReviewWeek
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Nature Reviews Neurology @natrevneurol.nature.com · 14/09/2026
Fibronectin mediates APOE4-driven blood–brain barrier dysfunction in Alzheimer’s disease idp.nature.com/authorize?re...
idp.nature.com
Fibronectin mediates APOE4-driven blood–brain barrier dysfunction in Alzheimer’s disease - Nature Aging
Bhattarai, Yilmaz and colleagues identify astrocyte-derived fibronectin as a key driver of blood–brain barrier dysfunction in Alzheimer’s disease, linking APOE ε4 and amyloid pathology to vascular dam...
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Dementia Researcher @dementiaresearcher.bsky.social · 12/09/2026
Research Technician role at @ukdri.ac.uk King’s College London supporting ALS research on FUS toxicity using transgenic mouse models, genotyping and tissue analysis. Closing date: 24th September www.dementiaresearcher.nihr.ac.uk/job/research...
dementiaresearcher.nihr.ac.uk
Research Technician: Neurodegeneration
King’s College London seeks a Research Technician to support ALS research on FUS toxicity using transgenic mouse models, genotyping and tissue analysis.
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Pedro Pimentel-Coelho @ppimentel-coelho.bsky.social · 05/09/2026
Oligodendrocyte dysfunction in human age-related cognitive decline Georgina A. Craig et al. 🧪 www.nature.com/articles/s41...
nature.com
Oligodendrocyte dysfunction in human age-related cognitive decline - Nature Medicine
This study identifies oligodendrocytes as active contributors to cognitive decline in aging, by leveraging a unique human brain bank with more than 70 years of associated cognitive data combined with ...
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Reposted by Isabel N Christie PhD
Konrad Kording @kordinglab.bsky.social · 24/08/2026
Hiring for research scientists in expansion chemistry and optical physiology at mindspan.org with @eboyden3.bsky.social, Yongxin Zhao, Xue Han. We will build tools to analyze the human brain. We are into compiling arxiv.org/abs/2603.25713. We are into cutting edge technology.
mindspan.org
Mindspan Institute
A non-profit creating and applying tools to characterize the molecules and wiring of the human brain, as well as to interpret how they contribute to brain functions and dysfunctions, openly sharing to...
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The Royal Society @royalsociety.org · 24/08/2026
Are you a researcher, policy maker or industry leader with an interest in the conservation of tropical forests? Register now to join our upcoming Science+ meeting in London on 5-6 October. royalsociety.org/science-even...
Promotional banner for a Royal Society event titled "Safeguarding Anthropocene tropical forests" (5–6 October 2026), listing organisers, set alongside an aerial photograph of a mist‑shrouded tropical rainforest.
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Baptiste Lacoste @blacoste.bsky.social · 24/08/2026
🚨 Want to isolate astrocytes and study their function? With Nicole Blakeley, PhD Candidate in our lab, we are happy to present a new protocol, which hopefully will help labs dive into glial biology with less hurdles. Cheers ! #glia #astrocytes
cell.com
Protocol for assessing molecular signatures and metabolic function of primary murine cortical astrocytes
Astrocytes are the most numerous brain cells and are central to the regulation of brain metabolism. Here, we present a protocol for identifying molecular signatures and assessing the metabolic functio...
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Reposted by Isabel N Christie PhD
Baptiste Lacoste @blacoste.bsky.social · 17/08/2026
Beautiful new paper by @dablab.bsky.social and team! "Pericyte KATP channel hyperactivity redistributes cortical blood flow in a CADASIL mouse model" #cerebrovascular
nature.com
Pericyte KATP channel hyperactivity redistributes cortical blood flow in a CADASIL mouse model - Nature Cardiovascular Research
By integrating spatial transcriptomics, advanced in vivo imaging, ex vivo myography, electrophysiology, in vitro functional assays and in silico modeling, Jeffrey et al. delineate a previously unrecog...
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Ashley Juavinett, PhD @ashleyjuavinett.bsky.social · 17/08/2026
let me phrase this differently: trainees: what papers did your advisors hand to you to read before starting your project? PIs: what papers do you share with your trainees?
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Matteo Carandini @carandinilab.net · 17/08/2026
I am proud of this paper. Since it came out in 2022 it has received 0 citations (yes that's a zero). But multiple young scientists have found it useful! (from other labs, so they were not coerced...). Perhaps you will find it useful too? SOME TIPS FOR WRITING SCIENCE doi.org/10.1523/ENEU...
doi.org
Some Tips for Writing Science
When preparing a scientific paper, we typically write with coauthors who have different backgrounds and styles, and we target readers who have little time and patience. To help both readers and writer...
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Isabel N Christie PhD @izzynchristie.bsky.social · 06/08/2026
Tau-induced mitochondrial reverse electron transport drives neurodegeneration: Neuron www.cell.com/neuron/fullt...
cell.com
Tau-induced mitochondrial reverse electron transport drives neurodegeneration
Mitochondrial dysfunction features prominently in tauopathies. The mechanistic link between tau and mitochondria remains uncertain. Li et al. show that tau enters mitochondria and interacts with compl...
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Reposted by Isabel N Christie PhD
Chunyu Ann Duan @annduan.bsky.social · 06/08/2026
New preprint from the lab! Behavioral and neural mechanisms for stochastic choices in mixed-strategy games: doi.org/10.64898/202... We use game theoretic tasks, cross species comparisons, modelling strategies, and mesoscale imaging to reveal a cortical mechanism for unpredictable choices.
doi.org
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Oliver @oliver48.bsky.social · 03/08/2026
If only the UK had massively subsidised the green economy with retraining for wind & solar and 100% home insulation instead of massively subsidising polluting but profitable oil and gas and warmongering ... meme via Neil McEvoy
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Isabel N Christie PhD @izzynchristie.bsky.social · 03/08/2026
Home from holiday to lots of negative peer review! Grateful to the reviewers for giving up their precious time 🙏🏻🙏🏻🙏🏻 Its the best thing about #science, we learn, we grow, we improve But wow it hurts 😞🤒🤕😣
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Mike Hudema @mikehudema.bsky.social · 02/08/2026
Another #renewable first for Scotland. Cars are now being charged by the power of the ocean. We have so many solutions. Implement them. #ActOnClimate #ClimateCrisis #Climate #energy #renewableenergy #greennewdeal
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alexvonwitzleben.bsky.social @alexvonwitzleben.bsky.social · 30/07/2026
#Spain combination of high solar irradiance, large available land, and aggressive #renewable auction programs has made it one of Europe's fastest-growing solar markets. #Solar regularly sets the marginal price in Spain's electricity market — meaning that when the sun shines, prices fall toward zero.
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Science Magazine @science.org · 30/07/2026
"The academic structure … makes planning for a family feel like an impossible luxury." In this Working Life, two postdocs share how, as women in academia, having children can feel impossible—and how talking about it makes them feel less alone. scim.ag/46uBWgD #InternationalDayOfFriendship
A conceputal illustration of multiple people looking to center, with conversation bubbles with baby and academic related drawings inside. Text reads: As women in academia, having children can feel impossible. Talking about it makes us feel less alone
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Drew Webb 🏳️‍🌈 @archeryfan93.bsky.social · 30/07/2026
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Physghoul 👻 🎃 @physgal.bsky.social · 28/07/2026
Fascinating paper on the progression of women in academia. 👩🏻‍🔬 ⚛️ 🧪 #AcademicSky docs.iza.org/dp18477.pdf?... Here's an excerpt from the conclusion:
When women do obtain tenure, the effects extend well beyond their own careers. Beyond the direct promotion of the qualifying candidate, departments experience on average one additional female promotion over the subsequent fifteen years, a substantial expansion of the female PhD pipeline, and improved retention and career progression among female doctoral graduates. These effects are concentrated in departments where women are underrepresented, but not entirely absent, suggesting that a minimal female presence is a precondition for trickle-down effects to materialize, whether through mutual support, departmental influence, or other channels that require women not to be entirely isolated.
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Mateusz Fafinski @calthalas.bsky.social · 29/07/2026
Half the planet is having a massive fight about how to correctly interpret an Ancient Greek poem but go ahead, close some more humanities departments.
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Damian Carrington @dpcarrington.bsky.social · 29/07/2026
Changing gas stove/hob to electric can help asthmatics as much - or more - than drugs - study #airpollution Story by @drgaryfuller.bsky.social www.theguardian.com/environment/...
theguardian.com
Replacing gas stove can help asthmatics as much as some drugs, US experts find
Team in Ohio finds swapping to electric has ‘very large’ impact, despite study being scaled back by Trump cuts
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Dementia Researcher @dementiaresearcher.bsky.social · 28/07/2026
Movement Disorders Fellowship at the University of Cambridge building clinical and research expertise in Parkinson’s, Lewy body dementia and related disorders. www.dementiaresearcher.nihr.ac.uk/job/assistan...
dementiaresearcher.nihr.ac.uk
Assistant Research Professor: Movement Disorders
University of Cambridge seeks a Movement Disorders Fellow to build clinical and research expertise in Parkinson’s, Lewy body dementia and related disorders.
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Simon Evans @drsimevans.carbonbrief.org · 28/07/2026
Wind and solar have just overtaken fossil-fuel power in Germany www.carbonbrief.org/...
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🇨🇦 l.faraday 🇨🇦 @mizati.bsky.social · 28/07/2026
The face of an ant under an electron microscope. Fascinating.
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Qasim Rashid, Esq. @qasimrashid.com · 26/07/2026
Mitch McConnell hasn’t been seen or heard from in 6 weeks(!) in the hospital. Yet he still has a job, still getting paid, and getting unlimited world class healthcare. The man who voted against a living wage, against universal healthcare, and against guaranteed paid leave—is now getting all three.
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Jason Shepherd @jasonsynaptic.bsky.social · 24/07/2026
Our paper is out in this week's issue of Cell! Personally, I think our cover submission by @drawimpacts.bsky.social was more exciting 😅 www.cell.com/cell/fulltex...
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Science Magazine @science.org · 23/07/2026
A prostaglandin prevents macrophages from clearing toxic neutrophils in aging organs, according to new Science research in mice. Learn more in a new #SciencePerspective: scim.ag/4fdUVBc
scim.ag
Tidying up aging organs
A prostaglandin prevents macrophages from clearing toxic neutrophils in aging organs
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Ishmail Abdus-Saboor @ishmailsaboor.bsky.social · 24/07/2026
Congratulations to Professor Wang on winning the Fields Medal (Nobel Prize for Math). Only the 3rd woman in history to win. And she won for a preprint article! We have some ways to go in biology before preprints receive this level of impact and recognition.
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Damian Carrington @dpcarrington.bsky.social · 23/07/2026
UK households free to install plug-in balcony #solar panels from end of August www.theguardian.com/money/2026/j...
theguardian.com
UK households free to install plug-in balcony solar panels from end of August
Law change means renters and flat owners may be able to cut bills as energy costs soar amid Iran war
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Isabel N Christie PhD @izzynchristie.bsky.social · 24/07/2026
Pisa Family time, loving holiday life ❤️ #WomeninSTEM #mothersinscience #familyfun #summerholidays #Italy #Tuscany
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Isabel N Christie PhD @izzynchristie.bsky.social · 22/07/2026
@ryanairofficial.bsky.social shocking scenes at Gate 49, flight to Milan. Stansted. Mother and child refused entry to flight at 10pm. Vicious, vindictive staff behaviour. All witnesses shocked and disgusted. Complaints coming soon
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Isabel N Christie PhD @izzynchristie.bsky.social · 22/07/2026
Never flying with Ryanair again. I just witnessed the most inhumane situation at Stansted airport. Staff were were rude and aggressive with a mother waiting to board her flight. She was refused entry to the flight. After an aggressive flight attendant demanded £60 for a child's suitcase
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samuel mehr @mehr.nz · 21/07/2026
the most realistic scene in Jurassic Park is when two scientists make a questionable decision — traveling to an undisclosed location with a strange man — on the promise of three years of modest funding
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IsThatDonHeath? @donjheath.bsky.social · 21/07/2026
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