Reposted by Isabel N Christie PhDMichael Okun @michael-okun.bsky.social · 30/09/2026A project that I've been working on for the last couple of years (on & off), dealing with the question of how firing rates of neuronal populations change (1/6). 1126
Reposted by Isabel N Christie PhDCiaran Murphy-Royal @murphyroyallab.org · 25/09/2026Come join us at the @crchum.bsky.social ! It really is as good as it looks! 11711
Reposted by Isabel N Christie PhDEmily Atkin @emorwee.bsky.social · 17/09/2026A few weekends ago I went to Miami and attended 9 open houses in extremely high-risk flood areas to see what agents are telling prospective buyers about them. Here is my journeyheated.worldThe open houses at the edge of disasterWhat are buyers being told about climate risk in Miami? I posed as one to find out. 421278408
Reposted by Isabel N Christie PhDSylvain Baillet @sylvainbaillet.bsky.social · 25/09/2026👉 Tenure-track opening in neuroscience @crchum.bsky.social @umontreal.ca crchum.carrieresante.gouv.qc.ca/poste/profes... 04133
Reposted by Isabel N Christie PhDDementia Researcher @dementiaresearcher.bsky.social · 24/09/2026Competition-funded Cambridge PhD with Dr Malpetti using blood and CSF biomarkers to map inflammation in frontotemporal dementia and predict disease progression. Closing date: 8th December www.dementiaresearcher.nihr.ac.uk/job/phd-flui...dementiaresearcher.nihr.ac.ukPhD: Fluid Biomarkers of Inflammation in Frontotemporal DementiaCompetition-funded Cambridge PhD with Dr Malpetti using blood and CSF biomarkers to map inflammation in frontotemporal dementia and predict disease progression. 011
Reposted by Isabel N Christie PhDGuardian US @us.theguardian.com · 23/09/2026"If a resurgent movement demands action, we finally have the tools to make that demand matter – a working planet that runs mostly on sun and wind is in tantalizing reach," writes @billmckibben.bsky.social. "At the last possible moment, with backs to the wall, we still have our face to the sun."theguardian.comThe climate fight has one great ally. You just can’t look at it directly | Bill McKibbenThere is hope in solar power. As the UN meets, we are urging leaders to pursue a clear goal: clean energy for all by 2030 111440
Reposted by Isabel N Christie PhDDementia Researcher @dementiaresearcher.bsky.social · 23/09/2026The Srinivasan Lab is looking for a Postdoctoral Scientist to work out how lymphatic vessels and heart valves develop, and what goes wrong in disease. The work uses mouse models, imaging and spatial transcriptomics. www.dementiaresearcher.nihr.ac.uk/job/postdoc-...dementiaresearcher.nihr.ac.ukPostdoc Scientist: Lymphatic and Cardiovascular Valve BiologyPostdoc at OMRF's Srinivasan Lab studying how lymphatic vessels and heart valves develop and fail, using mouse models, imaging and spatial transcriptomics. 002
Reposted by Isabel N Christie PhDWaggoner Lab @labwaggoner.bsky.social · 21/09/2026Review @cellcellpress.bsky.social Oligodendrocytes in central nervous system health and disease www.cell.com/cell/fulltex... 084
Reposted by Isabel N Christie PhDbioRxiv Neuroscience @biorxiv-neursci.bsky.social · 21/09/2026MALDI-TOF imaging mass spectrometry demonstrates sex- and age-dependent spatial changes in brain energy metabolism in response to amyloid stress using a mouse model of Alzheimers Disease www.biorxiv.org/content/10.64898/20… 021
Reposted by Isabel N Christie PhDbioRxiv Neuroscience @biorxiv-neursci.bsky.social · 18/09/2026Perivascular fibroblasts locally regulate the vasomotor dynamics of pial arterioles www.biorxiv.org/content/10.64898/20… 001
Reposted by Isabel N Christie PhDLifeCanvas Technologies @lifecanvastech.bsky.social · 18/09/2026Scientists at the @alleninstitute.org have made major strides in understanding one of the brain’s key neuromodulatory systems. Read on to learn more and check out the open access paper... 🧵 (1/5) 122
Reposted by Isabel N Christie PhDProf Jenny Rohn @jennyrohn.bsky.social · 04/09/2026Thrilled our latest paper out @natureportfolio.nature.com Nature Comms, lead author @microberamon.bsky.social, who developed P-FLO, a urine-flowing human micro-bladder model in collab with Oxford & Leicester to understand #UTI biology & treatment failure 1/4 #UTISky www.nature.com/articles/s41...nature.comEffect of human urinary microenvironment and fluid flow on antibiotic and phage therapy efficacy against uropathogenic Escherichia coli - Nature CommunicationsMaset et al. show that bladder conditions strongly influence how urinary tract infections respond to antibiotics and bacteriophages, highlighting the need for more realistic lab models to improve diag... 44216
Reposted by Isabel N Christie PhDScience News @scinews.bsky.social · 15/09/2026Obesity impairs neuronal, microglial, metabolic and cerebrovascular function in the hippocampus, prefrontal cortex, white matter and other regions that are crucial for cognition, mirroring changes observed in ageing and dementia. www.nature.com/articles/s41... 042
Reposted by Isabel N Christie PhDallen institute @alleninstitute.org · 14/09/2026Open science means data, software, lab protocols, cell lines, and even custom microscope designs freely available to everyone, so researchers can build on each other's work instead of starting from scratch. More collaboration = faster discoveries. 121
Reposted by Isabel N Christie PhDallen institute @alleninstitute.org · 14/09/2026It's #OpenScienceWeek! Research can be expensive, competitive, and surprisingly hard to share. Paywalls, data barriers, and the race to publish have historically kept discoveries locked away. Open science is the movement to change that. 163
Reposted by Isabel N Christie PhDEliezyer de Oliveira @eliezyer.bsky.social · 14/09/2026After a long journey through review, our paper is finally out in Nature Communications. We started with a simple problem: The visual cortex is strongly modulated by movement. So how can it represent the visual world without movement interfering with everything? www.nature.com/articles/s41... 518139
Reposted by Isabel N Christie PhDScience Magazine @science.org · 14/09/2026Increasing the breadth of researchers trained as reviewers is crucial. In 2024, we began a program that invites reviewers to add trainees as co-reviewers. Nearly 6000 scientists have participated. All our reviewers, past and present, can now get credit on ORCID. #PeerReviewWeek 0397
Reposted by Isabel N Christie PhDNature Reviews Neurology @natrevneurol.nature.com · 14/09/2026Fibronectin mediates APOE4-driven blood–brain barrier dysfunction in Alzheimer’s disease idp.nature.com/authorize?re...idp.nature.comFibronectin mediates APOE4-driven blood–brain barrier dysfunction in Alzheimer’s disease - Nature AgingBhattarai, Yilmaz and colleagues identify astrocyte-derived fibronectin as a key driver of blood–brain barrier dysfunction in Alzheimer’s disease, linking APOE ε4 and amyloid pathology to vascular dam... 0137
Reposted by Isabel N Christie PhDDementia Researcher @dementiaresearcher.bsky.social · 12/09/2026Research Technician role at @ukdri.ac.uk King’s College London supporting ALS research on FUS toxicity using transgenic mouse models, genotyping and tissue analysis. Closing date: 24th September www.dementiaresearcher.nihr.ac.uk/job/research...dementiaresearcher.nihr.ac.ukResearch Technician: NeurodegenerationKing’s College London seeks a Research Technician to support ALS research on FUS toxicity using transgenic mouse models, genotyping and tissue analysis. 002
Reposted by Isabel N Christie PhDPedro Pimentel-Coelho @ppimentel-coelho.bsky.social · 05/09/2026Oligodendrocyte dysfunction in human age-related cognitive decline Georgina A. Craig et al. 🧪 www.nature.com/articles/s41...nature.comOligodendrocyte dysfunction in human age-related cognitive decline - Nature MedicineThis study identifies oligodendrocytes as active contributors to cognitive decline in aging, by leveraging a unique human brain bank with more than 70 years of associated cognitive data combined with ... 1104
Reposted by Isabel N Christie PhDKonrad Kording @kordinglab.bsky.social · 24/08/2026Hiring for research scientists in expansion chemistry and optical physiology at mindspan.org with @eboyden3.bsky.social, Yongxin Zhao, Xue Han. We will build tools to analyze the human brain. We are into compiling arxiv.org/abs/2603.25713. We are into cutting edge technology.mindspan.orgMindspan InstituteA non-profit creating and applying tools to characterize the molecules and wiring of the human brain, as well as to interpret how they contribute to brain functions and dysfunctions, openly sharing to... 31812
Reposted by Isabel N Christie PhDThe Royal Society @royalsociety.org · 24/08/2026Are you a researcher, policy maker or industry leader with an interest in the conservation of tropical forests? Register now to join our upcoming Science+ meeting in London on 5-6 October. royalsociety.org/science-even... 422
Reposted by Isabel N Christie PhDBaptiste Lacoste @blacoste.bsky.social · 24/08/2026🚨 Want to isolate astrocytes and study their function? With Nicole Blakeley, PhD Candidate in our lab, we are happy to present a new protocol, which hopefully will help labs dive into glial biology with less hurdles. Cheers ! #glia #astrocytescell.comProtocol for assessing molecular signatures and metabolic function of primary murine cortical astrocytesAstrocytes are the most numerous brain cells and are central to the regulation of brain metabolism. Here, we present a protocol for identifying molecular signatures and assessing the metabolic functio... 0136
Reposted by Isabel N Christie PhDBaptiste Lacoste @blacoste.bsky.social · 17/08/2026Beautiful new paper by @dablab.bsky.social and team! "Pericyte KATP channel hyperactivity redistributes cortical blood flow in a CADASIL mouse model" #cerebrovascularnature.comPericyte KATP channel hyperactivity redistributes cortical blood flow in a CADASIL mouse model - Nature Cardiovascular ResearchBy integrating spatial transcriptomics, advanced in vivo imaging, ex vivo myography, electrophysiology, in vitro functional assays and in silico modeling, Jeffrey et al. delineate a previously unrecog... 083
Reposted by Isabel N Christie PhDAshley Juavinett, PhD @ashleyjuavinett.bsky.social · 17/08/2026let me phrase this differently: trainees: what papers did your advisors hand to you to read before starting your project? PIs: what papers do you share with your trainees? 155
Reposted by Isabel N Christie PhDMatteo Carandini @carandinilab.net · 17/08/2026I am proud of this paper. Since it came out in 2022 it has received 0 citations (yes that's a zero). But multiple young scientists have found it useful! (from other labs, so they were not coerced...). Perhaps you will find it useful too? SOME TIPS FOR WRITING SCIENCE doi.org/10.1523/ENEU...doi.orgSome Tips for Writing ScienceWhen preparing a scientific paper, we typically write with coauthors who have different backgrounds and styles, and we target readers who have little time and patience. To help both readers and writer... 616554
Isabel N Christie PhD @izzynchristie.bsky.social · 06/08/2026Tau-induced mitochondrial reverse electron transport drives neurodegeneration: Neuron www.cell.com/neuron/fullt...cell.comTau-induced mitochondrial reverse electron transport drives neurodegenerationMitochondrial dysfunction features prominently in tauopathies. The mechanistic link between tau and mitochondria remains uncertain. Li et al. show that tau enters mitochondria and interacts with compl... 000
Reposted by Isabel N Christie PhDChunyu Ann Duan @annduan.bsky.social · 06/08/2026New preprint from the lab! Behavioral and neural mechanisms for stochastic choices in mixed-strategy games: doi.org/10.64898/202... We use game theoretic tasks, cross species comparisons, modelling strategies, and mesoscale imaging to reveal a cortical mechanism for unpredictable choices.doi.org 1356
Reposted by Isabel N Christie PhDOliver @oliver48.bsky.social · 03/08/2026If only the UK had massively subsidised the green economy with retraining for wind & solar and 100% home insulation instead of massively subsidising polluting but profitable oil and gas and warmongering ... meme via Neil McEvoy 12586263
Isabel N Christie PhD @izzynchristie.bsky.social · 03/08/2026Home from holiday to lots of negative peer review! Grateful to the reviewers for giving up their precious time 🙏🏻🙏🏻🙏🏻 Its the best thing about #science, we learn, we grow, we improve But wow it hurts 😞🤒🤕😣 110
Reposted by Isabel N Christie PhDMike Hudema @mikehudema.bsky.social · 02/08/2026Another #renewable first for Scotland. Cars are now being charged by the power of the ocean. We have so many solutions. Implement them. #ActOnClimate #ClimateCrisis #Climate #energy #renewableenergy #greennewdeal 214963
Reposted by Isabel N Christie PhDalexvonwitzleben.bsky.social @alexvonwitzleben.bsky.social · 30/07/2026#Spain combination of high solar irradiance, large available land, and aggressive #renewable auction programs has made it one of Europe's fastest-growing solar markets. #Solar regularly sets the marginal price in Spain's electricity market — meaning that when the sun shines, prices fall toward zero. 6534791007
Reposted by Isabel N Christie PhDScience Magazine @science.org · 30/07/2026"The academic structure … makes planning for a family feel like an impossible luxury." In this Working Life, two postdocs share how, as women in academia, having children can feel impossible—and how talking about it makes them feel less alone. scim.ag/46uBWgD #InternationalDayOfFriendship 04414
Reposted by Isabel N Christie PhDPhysghoul 👻 🎃 @physgal.bsky.social · 28/07/2026Fascinating paper on the progression of women in academia. 👩🏻🔬 ⚛️ 🧪 #AcademicSky docs.iza.org/dp18477.pdf?... Here's an excerpt from the conclusion: 010852
Reposted by Isabel N Christie PhDMateusz Fafinski @calthalas.bsky.social · 29/07/2026Half the planet is having a massive fight about how to correctly interpret an Ancient Greek poem but go ahead, close some more humanities departments. 3558911659
Reposted by Isabel N Christie PhDDamian Carrington @dpcarrington.bsky.social · 29/07/2026Changing gas stove/hob to electric can help asthmatics as much - or more - than drugs - study #airpollution Story by @drgaryfuller.bsky.social www.theguardian.com/environment/...theguardian.comReplacing gas stove can help asthmatics as much as some drugs, US experts findTeam in Ohio finds swapping to electric has ‘very large’ impact, despite study being scaled back by Trump cuts 02918
Reposted by Isabel N Christie PhDDementia Researcher @dementiaresearcher.bsky.social · 28/07/2026Movement Disorders Fellowship at the University of Cambridge building clinical and research expertise in Parkinson’s, Lewy body dementia and related disorders. www.dementiaresearcher.nihr.ac.uk/job/assistan...dementiaresearcher.nihr.ac.ukAssistant Research Professor: Movement DisordersUniversity of Cambridge seeks a Movement Disorders Fellow to build clinical and research expertise in Parkinson’s, Lewy body dementia and related disorders. 001
Reposted by Isabel N Christie PhDSimon Evans @drsimevans.carbonbrief.org · 28/07/2026Wind and solar have just overtaken fossil-fuel power in Germany www.carbonbrief.org/... 181399352
Reposted by Isabel N Christie PhD🇨🇦 l.faraday 🇨🇦 @mizati.bsky.social · 28/07/2026The face of an ant under an electron microscope. Fascinating. 1571444203
Reposted by Isabel N Christie PhDQasim Rashid, Esq. @qasimrashid.com · 26/07/2026Mitch McConnell hasn’t been seen or heard from in 6 weeks(!) in the hospital. Yet he still has a job, still getting paid, and getting unlimited world class healthcare. The man who voted against a living wage, against universal healthcare, and against guaranteed paid leave—is now getting all three. 1152220687394
Reposted by Isabel N Christie PhDJason Shepherd @jasonsynaptic.bsky.social · 24/07/2026Our paper is out in this week's issue of Cell! Personally, I think our cover submission by @drawimpacts.bsky.social was more exciting 😅 www.cell.com/cell/fulltex... 3286
Reposted by Isabel N Christie PhDScience Magazine @science.org · 23/07/2026A prostaglandin prevents macrophages from clearing toxic neutrophils in aging organs, according to new Science research in mice. Learn more in a new #SciencePerspective: scim.ag/4fdUVBc scim.agTidying up aging organsA prostaglandin prevents macrophages from clearing toxic neutrophils in aging organs 0305
Reposted by Isabel N Christie PhDIshmail Abdus-Saboor @ishmailsaboor.bsky.social · 24/07/2026Congratulations to Professor Wang on winning the Fields Medal (Nobel Prize for Math). Only the 3rd woman in history to win. And she won for a preprint article! We have some ways to go in biology before preprints receive this level of impact and recognition. 14613
Reposted by Isabel N Christie PhDDamian Carrington @dpcarrington.bsky.social · 23/07/2026UK households free to install plug-in balcony #solar panels from end of August www.theguardian.com/money/2026/j...theguardian.comUK households free to install plug-in balcony solar panels from end of AugustLaw change means renters and flat owners may be able to cut bills as energy costs soar amid Iran war 46029
Isabel N Christie PhD @izzynchristie.bsky.social · 24/07/2026Pisa Family time, loving holiday life ❤️ #WomeninSTEM #mothersinscience #familyfun #summerholidays #Italy #Tuscany 020
Isabel N Christie PhD @izzynchristie.bsky.social · 22/07/2026@ryanairofficial.bsky.social shocking scenes at Gate 49, flight to Milan. Stansted. Mother and child refused entry to flight at 10pm. Vicious, vindictive staff behaviour. All witnesses shocked and disgusted. Complaints coming soon 010
Isabel N Christie PhD @izzynchristie.bsky.social · 22/07/2026Never flying with Ryanair again. I just witnessed the most inhumane situation at Stansted airport. Staff were were rude and aggressive with a mother waiting to board her flight. She was refused entry to the flight. After an aggressive flight attendant demanded £60 for a child's suitcase 010
Reposted by Isabel N Christie PhDsamuel mehr @mehr.nz · 21/07/2026the most realistic scene in Jurassic Park is when two scientists make a questionable decision — traveling to an undisclosed location with a strange man — on the promise of three years of modest funding 365717847