Nature Neuroscience - Senne, Suthard and colleagues show that dorsal hippocampal astrocytes display time-compressed calcium-event sequences after foot shock and upon context re-exposure, and that...

How do people preserve mental continuity when tasks are interrupted? One established pathway runs through the hippocampus, which stores snapshots of our mental context for later reinstatement. We prop...

Assistive algorithms are widely used in brain-computer interfaces (BCIs), but their effects on neural representations remain unclear. Here, the authors show that adaptive BCIs lead the brain to learn ...

Innate preferences determine how animals interact with the environment, but how experience refines the neural processes underlying those intrinsic motivations is not well understood. Here we develop a...

Chericoni et al. show that neurons in the human hippocampus track the positions of multiple agents in a simple pursuit-based video game. They identified place codes for each agent and for gaze. The co...

In mice, a sparse population of sleep-active long-range inhibitory neurons in the neocortex promote widespread cortical synchronization and sleep, revealing a cortical mechanism that co...

Researcher Matthew Nock pioneered the technique of using smartphone technology to survey high-risk adults and adolescents in real time. In a new study, Nock and his team report using the technology to...

An imaging system developed to record cellular activity throughout the whole body of zebrafish captures cellular organ dynamics and identifies multiple distributed circuits.

Synchronized and desynchronized patterns of spontaneous activity during brain development prepare cortical circuits such as the visual cortex for processing external sensory information. Yet the neuro...

GNB1 encephalopathy (GNB1-E) is a rare neurodevelopmental disorder associated with motor dysfunction, epilepsy and learning disability caused by mutations in the gene encoding the G protein subunit Gβ...

In macaques, old memories, relative to new ones, are supported by more stable and interconnected cell assemblies. New-biased and old-biased assemblies reactivate during overnight sleep and can sometim...

Transmissible tumors have been reported in a handful of animal species, but never before among fish. Is it possible in humans?

Thompson, Rollik and colleagues show that, during sleep, the brain replays procedural memories in the striatum independently of the hippocampus. Replay content was shaped by prior reward and error out...

Arizona’s Supplemental Nutrition Assistance Program rolls have plummeted, offering a possible preview of national trends as states try to avoid new federal penalties.

Summary: Biological motion can be difficult to define and measure. Optical flow is uniquely suited to this challenge. We provide tools for 3D optical flow and illustrate its use in extracting biologic...

Flexible behavior requires using past experiences to configure cortical computations to suit current task demands. A central question in neuroscience is how memory representations control such reconfi...

Throughout the mammalian cortex, populations of neurons must work together to enact behaviors. While population recordings in motor cortex have revealed many aspects of when neurons fire during behavi...

A long-range inhibitory projection from the basal forebrain disinhibits the cortex to amplify sensory responses. This circuit encodes motivational salience and predicts moment-to-moment attentional pe...

Orientation tuning—the ability to distinguish a horizontal line from a vertical one or something in between—originates in the visual cortex.

Standard animal learning studies minimize individual reward magnitudes to maximize the repetitions of reinforced behaviors. We investigated how reward magnitude influences initial learning across five...

YouTube video by Max S