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Luke Sjulson

@lukesjulson.bsky.social
4.4K followers 2.5K following 634 posts

MD/PhD neuroscientist/psychiatrist, father of 3, Nak Muay, engineer at heart. mPFC-HPC in addiction/schizophrenia, multi-region ephys and imaging in vivo, novel optical methods for spatial transcriptomics and latent molecular states sjulsonlab.org

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Luke Sjulson @lukesjulson.bsky.social · 03/10/2026
I found this so funny because the smell of phenol/chloroform brings back such nostalgia for my own good old days
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Luke Sjulson @lukesjulson.bsky.social · 30/09/2026
Manuscript submitted! 🍻🥳🎉
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Luke Sjulson @lukesjulson.bsky.social · 30/09/2026
Today I woke up my kids by playing the song “Wake Up,” and I learned my 12yo thought it was Rage Against the Machines with an S, as in she thought it was robots and AI. Weirdly, in today’s society, that actually makes more sense “It’s about the political system? but it’s in The Matrix soundtrack!”
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NE Ohio Regional Sewer District @neorsd.org · 29/09/2026
bold and wildly inexplicable photo choice here
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Luke Sjulson @lukesjulson.bsky.social · 29/09/2026
This is truly awful. We all need to fight against this
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BWJones @bwjones.bsky.social · 25/09/2026
Science peeps: Looks like SciENcv updated the digital certificate used to sign Biosketch and Current & Pending documents without notification. The old certificate expires Saturday, September 26, 2026. SciENcv docs before that date may fail validation in eRA Commons delaying or blocking submission.
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Luke Sjulson @lukesjulson.bsky.social · 20/09/2026
Lots of conversations about whether AI can reason and etc. are frustratingly conflating several separate issues: 🧵 1) Could a future AI reason and have consciousness? Yes, in principle. Brains do not have magic capabilities that machines cannot have. At least, that's what neuroscience
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Luke Sjulson @lukesjulson.bsky.social · 18/09/2026
I have no idea where this is from, but @philoneurosci.bsky.social posted it on our lab slack, and it was so good I had to share it
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Mazen Kheirbek @mazenkheirbek.bsky.social · 14/09/2026
Our new review is out now on the ventral hippocampus, highlighting a large body of recent work, from the information it represents to how internal state shapes its activity to how its circuits influence behavior.
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Luke Sjulson @lukesjulson.bsky.social · 15/09/2026
With the beginning of the new academic year, I'm reposting the info for our free online neuroscience methods course. If you're starting a PhD in neuroscience, or just want a refresher, this is for you!
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Luke Sjulson @lukesjulson.bsky.social · 14/09/2026
After an unusually grueling review process, it’s finally out! Elie and Soyoun really did a fantastic job with this one
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Luke Sjulson @lukesjulson.bsky.social · 09/09/2026
Congrats to Renata Batista-Brito, Geoffrey, and Jacob on this monster paper! It’s an amazing piece of work, and I’m thrilled I got the chance to contribute to it
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derek guy @dieworkwear.bsky.social · 06/09/2026
this is the kind of design costume designers make to tell you who are the bad guys in a space movie
Donald Trump posts an image on his Truth Social account. It shows a new uniform for US Space Force members, comprising of an all-black outfit with knee-high black leather boots, black cap, and minimalist looking suit.
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Luke Sjulson @lukesjulson.bsky.social · 02/09/2026
According to the replies, some programs still require accepted papers for a student to graduate. In other words, anonymous reviewers get to decide when PhDs are conferred. I think that is absolutely insane
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Gaute Einevoll @gauteeinevoll.bsky.social · 27/08/2026
I am very happy that the Theoretical Neuroscience Podcast (theoreticalneuroscience.no) is now featured in TheTransmitter. My goal is that everyone in the field should at least know about the podcast, whether they would like to listen to it or not. And being featured here is a big help. Thanks!
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Luke Sjulson @lukesjulson.bsky.social · 27/08/2026
This is a fantastic free meeting that I recommend highly for everyone in the NYC area, particularly trainees. Please repost!
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Tim Verstynen @tdverstynen.bsky.social · 12/08/2026
She’s a professor working in my field. She has no criminal record. Neither does her son. Neither does her husband. Yet they have all been kidnapped and sent to a concentration camp where they’ve languished for months in horrid conditions. Don’t for a second think they’ll stop at immigrants.
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Luke Sjulson @lukesjulson.bsky.social · 07/08/2026
I just showed my 6th grader clips of Clay Davis saying sheeeeeit until she was able to replicate it perfectly. Someday that skill will serve her well
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ghost malone ergo propter bones @proptermalone.bsky.social · 02/08/2026
and GOD IS EMPTY JUST LIKE ME
democrat is socialist and socialist is communist
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Mark Histed @markhisted.org · 24/07/2026
Also: We keep hearing that a number of Congressmembers think that everything at NIH has gone back to normal, and the Trump appointees are in fact on the side of saving NIH. That is false. Things at NIH are WORSE than last year. Please reach out to your senators and reps and tell them that.
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Luke Sjulson @lukesjulson.bsky.social · 22/07/2026
Every once in a while, I come across something that reminds me of how great the internet used to be in the 2000s. Most recently, this website with animations teaching you to tie 196 different knots: www.animatedknots.com/complete-kno...
animatedknots.com
Complete Knot List
Knots in Alphabetical Order. There are 196 knots listed (animated) and 374 total knots as some knots are known by several names. Select by Activity, Type or Search for Knots.
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Dimitra Maoutsa @dimma.bsky.social · 06/07/2026
Our Impact Scholars @neuromatch.bsky.social project on 𝗵𝗼𝘄 𝗿𝗲𝘄𝗮𝗿𝗱 𝘃𝘀 𝗲𝘅𝗽𝗲𝗿𝗶𝗲𝗻𝗰𝗲 𝘀𝗵𝗮𝗽𝗲 𝗻𝗲𝘂𝗿𝗮𝗹 𝗽𝗼𝗽𝘂𝗹𝗮𝘁𝗶𝗼𝗻 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 𝗶𝗻 𝗺𝗼𝘂𝘀𝗲 𝘃𝗶𝘀𝘂𝗮𝗹 𝗰𝗼𝗿𝘁𝗲𝘅 is out! 
 With 𝗝𝗼𝗵𝗻 𝗠𝗮𝗱𝗿𝗶𝗱-𝗖𝗮𝗿𝘃𝗮𝗷𝗮𝗹 @johnmadridcarvajal.bsky.social, 𝗞𝗮𝘁𝗷𝗮 𝗞𝗮𝘂𝗿𝗶𝗻𝗸𝗼𝘀𝗸𝗶, 𝗜𝘀𝗵𝗮𝘁𝗽𝗿𝗲𝗲𝘁 𝗦𝗶𝗻𝗴𝗵, 𝗥𝗼𝗵𝗶𝘁 𝗝𝗲𝘀𝘄𝗮𝗻𝘁𝗵. 🧠 👉 zenodo.org/records/2064... 🧵👇 1/8
Schematic of the experimental setup and our analysis. Mice experienced visual corridors containing leaf or circle patterns, with reward available only for one pattern in the rewarded cohort and no reward in the unrewarded cohort. Large-scale calcium imaging sampled neurons across V1 and higher visual areas before and after learning. Neural activity was organised into neuron × time × trial tensors and analysed with tensor component analysis. Example factors show differences between rewarded and unrewarded mice before versus after learning, including stronger separation of leaf and circle trials after rewarded learning.
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Luke Sjulson @lukesjulson.bsky.social · 06/07/2026
Want to understand the new OMB rules and why many researchers are concerned? @rossenator.bsky.social put together an outstanding video series: www.youtube.com/playlist?lis... She also compiled advocacy resources: github.com/rrosslab/Pol... Please like and repost so they reach a wider audience!
youtube.com
Take Action for Science and Public Health - YouTube
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Noémi Éltető @noemielteto.bsky.social · 19/06/2026
First paper since joining Google DeepMind! We present 🌍ATLAS (Active Theory Learning for Automated Science), a pipeline that generates interpretable mechanistic models from data and optimizes experiments to test them. Thread below
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Heather Anne Campbell @heathercampbell.bsky.social · 24/06/2026
can’t believe a narcissist is being so publicly humiliated by a reflecting pool
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Michael E. Mann @michaelemann.bsky.social · 23/06/2026
The lowly cyanobacteria defeating Trump has such a "War of the Worlds" vibe to it...
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Luke Sjulson @lukesjulson.bsky.social · 17/06/2026
People like to dunk on MATLAB now, but it’s hard to overstate how large an advance it was at the time and the impact it has had on scientific computing. RIP Cleve Moler www.nytimes.com/2026/06/11/s...
nytimes.com
Cleve Moler, Who Unlocked the Power of Computing for Millions, Dies at 86
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Brandon @bedubble.bsky.social · 14/06/2026
This was only possible because of congestion pricing
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Luke Sjulson @lukesjulson.bsky.social · 14/06/2026
Wild times in Harlem. I hope everyone stays safe
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Luke Sjulson @lukesjulson.bsky.social · 14/06/2026
Absolute madness in Harlem right now. People are dancing in the streets
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Mark Histed @markhisted.org · 11/06/2026
Neuroscientist here, who has talked about the US losing science ground to other countries: The biggest problem for generating future cures for brain diseases is the ongoing utter destruction of US basic neuroscience. It’s not about regulation.
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Luke Sjulson @lukesjulson.bsky.social · 09/06/2026
This week in Nature Protocols: training yellow-legged hornets to implant #neuropixels probes
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Jens-Bastian Eppler @j-b-eppler.bsky.social · 31/05/2026
New preprint: Random network structure stabilizes neural manifolds We’re excited to share our new work on representational drift. doi.org/10.64898/202... Representational drift poses a puzzle. 👇 A short thread below. In the next days a figure by figure walk through will follow. 1/5 🧪🧠
doi.org
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Luke Sjulson @lukesjulson.bsky.social · 24/05/2026
I remember auditing a math class as a 1st yr md/phd student, and the professor looked like Walt Whitman with one arm covered in chalk dust up to the elbow. He was shouting: “Every open cover has a finite subcover! No holes!” And that was the moment I became an experimentalist
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Marcus Siems @marcussiems.bsky.social · 18/05/2026
„Rhythmic sampling of decision alternatives through attention“ 🔦 Spotlight of our recent work in @cp-trendscognsci.bsky.social by Alireza Valizadeh www.cell.com/trends/cogni...
cell.com
Rhythmic sampling of decision alternatives through attention
Recent work by Siems et al. shows that the brain rhythmically samples competing alternatives through covert spatial attention. This challenges continuous models of decision-making and suggests that ev...
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Abraham Palmer @abepalmer.bsky.social · 15/05/2026
A colleague received bad news from her NIH program officer today: my colleague’s grant got a great score, but NIH still can’t pay it, and my colleague will have to closer her lab. The call ended with the program officer (not my colleague) crying. Awful on so many levels.
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Luke Sjulson @lukesjulson.bsky.social · 15/05/2026
What’s interesting to me about this sculpture is that the doctor has excellent form, keeping his chin tucked below his shoulder when using the Muay Thai long guard
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Luke Sjulson @lukesjulson.bsky.social · 15/05/2026
People supporting arxiv’s policy on LLM use haven’t thought through the unintended consequences of PERMANENTLY banning ALL COAUTHORS. The 16th author on your 20-author paper didn’t check all the refs on a paper many ago? Now YOU can’t post the preprint on arxiv. Starting a collaboration? Better 1/
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Luke Sjulson @lukesjulson.bsky.social · 13/05/2026
Part of me is shocked by this, and part of me feels like of course Kozak sequences weren’t the whole story. Either way, it’s nice to see someone finally nailed it down
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Luke Sjulson @lukesjulson.bsky.social · 19/04/2026
Nora Volkow looks taller than Joe Rogan
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Agnès Landemard @agnesland.bsky.social · 15/04/2026
How does blood flow relate to brain activity? We discovered that it reflects two neural populations affected oppositely by arousal. Together, they explain neurovascular coupling in all brain regions and brain states! Out today in Nature: rdcu.be/fdC2A @uclbrainscience.bsky.social
The supply of blood to brain tissue is thought to depend on the overall neural activity in that tissue, and this dependence is thought to differ across brain regions and across brain states. However, studies supporting these views have measured neural activity as a bulk quantity and related it to blood supply following disparate events in different regions. Here we measure fluctuations in neuronal activity and blood volume across the mouse brain, and find that their relationship is consistent across brain states and brain regions but differs in two opposing brainwide neural populations. Functional ultrasound imaging (fUSI) revealed that whisking, a marker of arousal, is associated with brainwide fluctuations in blood volume. Simultaneous fUSI and Neuropixels recordings showed that neurons that increase activity with whisking have distinct haemodynamic response functions compared with those that decrease activity. Their summed contributions predicted blood volume across states.Brainwide Neuropixels recordings revealed that these opposing populations coexist in the entire brain. Their differing contributions to blood volume largely explain the apparent differences in blood volume fluctuations across regions. The mouse brain thus contains two neural populations with opposite relations to brain state and distinct relationships to blood supply, which together account for brainwide fluctuations in blood volume.
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Georg Keller @georgkeller.bsky.social · 15/04/2026
For nearly a century, we believed the therapeutic effect of ECT is the seizure. Our latest research suggests we may have been looking at the wrong event. A thread on why cortical spreading depression (CSD) might be the driver of therapeutic benefit. Work led by @therehugolad.bsky.social
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Bita Moghaddam @bita137.bsky.social · 06/04/2026
Sharif University in Tehran was just bombed Founded in 1965, it is one the most elite science and engineering institutions in the world. Alumni include the mathematician Maryam Mirzakhani, first woman to win the Fields Medal Here is the list of other alumni en.wikipedia.org/wiki/List_of...
en.wikipedia.org
List of Sharif University of Technology people - Wikipedia
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Rudebeck Lab @rudebecklab.bsky.social · 04/04/2026
Want a dataset to test ideas on neural basis of decision making or how areas interact as we make choices? Check out our data published today @rudebecklab.bsky.social. >16,000 single neurons from 22 anatomically confirmed areas in macaques performing a decision task. www.nature.com/articles/s41...
nature.com
Dataset of cortical and subcortical single neuron activity during value-based tasks in macaque monkey - Scientific Data
Scientific Data - Dataset of cortical and subcortical single neuron activity during value-based tasks in macaque monkey
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Matt @mavarus.bsky.social · 02/04/2026
nasa employee: oh hey u guys are back early astronaut: Office365 in spaceship nasa employee: what? astronaut: *loading a pistol and getting back on the rocket-ship* Office365 in spaceship
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Luke Sjulson @lukesjulson.bsky.social · 02/04/2026
Coming back from the Molecular Psychiatry meeting I got randomly upgraded to first class, and now I’m chugging free prosecco and taking selfies like a common peasant
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Spencer LaVere Smith @spencerlaveresmith.bsky.social · 27/02/2026
Two-photon calcium imaging at 24,000 lines/s, with the resonant axis spanning 4x what other systems can do. Inertia-free. Diffraction-limited. No tradeoffs. Che-Hang Yu developed a 4x angle multiplier for laser scanning. His paper is out today: opg.optica.org/optica/fullt... 1/n #fluorescenceFriday
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Protik Islam-Jakobsson @protik.bsky.social · 25/03/2026
Keanu Reeves as Tom Bombadil coming out of retirement for one last job
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Luke Sjulson @lukesjulson.bsky.social · 22/03/2026
11yo: I’m so sick of the boys in my class. Did you know two of them are named Rexford and Brid? They should be on a lacrosse team, not in my class
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Jessica Tollkuhn @tollkuhn.bsky.social · 22/03/2026
I said “oh no” out loud when ryan gosling didn’t balance the centrifuge
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