Cyclin-dependent kinase 9 (CDK9) inhibition represents a promising therapeutic strategy in cancers that disrupts RNA polymerase II pause release and collapses oncogenic transcripts. Here, we show that...

In eukaryotes, ribosome biogenesis initiates within the nucleolus, a hallmark multilayered compartment of the nucleus. Structures of pre-ribosomes have been characterized ex situ, but their assembly p...

In eukaryotes, ribosome biogenesis initiates within the nucleolus, a hallmark multilayered compartment of the nucleus. Structures of pre-ribosomes have been characterized ex situ, but their assembly p...

By Dr. Douglas R. Waverly, Professor Emeritus of Biochemistry, Yale University

Telomeres have the crucial role of protecting chromosome ends and its length varies significantly between organisms. What evolutionary factor shapes this natural variation has been a long standing que...

Cell-cycle remodeling is fundamental to pluripotency and lineage commitment, yet whether its transcriptional and post-transcriptional architecture is conserved across species and developmental states ...

We are looking for a self-motivated, enthusiastic research assistant to join the laboratory of Dr Duncan Sproul at the University of Edinburgh’s Institute of Genetics and Cancer and support research i...

An online platform removed 257 papers written or co-written by the University of Chicago’s Nicholas Polson after other academics raised questions.

In memoriam: Professor Timothy H. Bestor 1952-2026

In memoriam: Professor Timothy H. Bestor 1952-2026

Theory can help address cell and molecular biology’s major challenges, particularly those arising from large omics datasets.

Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...

We hope you can join us for a fun and inspiring in-person gathering.