The facial skeleton is essential for eating, breathing, kissing, speech and personal identity. Our spatiotemporally resolved cell atlas of human embryonic craniofacial development will facilitate a de...

Ein schwarzer Cambridge-Professor gerät ins Visier eines selbsternannten „Rassenrealisten“. Der Fall Jason Arday und was er für die Wissenschaft bedeutet.

CRISPR-associated transposons mediate RNA-guided DNA integration, but the molecular basis of transposase function remains poorly understood. Here, the authors uncover the mechanism of a highly active ...

Using carbon tracing and functional experiments, Kafkia, Pladevall-Morera, et al. show that TCA cycle rewiring underlies mouse embryo implantation and the exit from naive pluripotency. In this context...

Naive human pluripotent stem cells (hPSCs) represent a pre-implantation epiblast state able to efficiently differentiate into embryonic and extraembryonic pre-implantation lineages and to self-organis...