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John Greally

@greally.bsky.social
2K followers 689 following 572 posts

Using genomic information to improve medicine

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John Greally @greally.bsky.social · 24/09/2026
South Atlanta, street art
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TW @twesq.bsky.social · 20/09/2026
this is fantastic and I learned something new
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John Greally @greally.bsky.social · 23/09/2026
Maith thú a Chaoimhín! @wiringthebrain.bsky.social
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John Greally @greally.bsky.social · 23/09/2026
Tim Bestor has left us. This obituary captures him well — you always had to be at your intellectual peak with him, while his trainees always spoke highly of their experiences. He made a massive contribution to epigenetics, a giant in our field. www.genetics.cuimc.columbia.edu/news/memoria...
genetics.cuimc.columbia.edu
In memoriam of Professor Timothy H. Bestor
In memoriam: Professor Timothy H. Bestor 1952-2026
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John Greally @greally.bsky.social · 16/09/2026
This is a common Bronx story. People there do not deserve to live under such pressure when wealth abounds in NYC www.nytimes.com/interactive/...
nytimes.com
How a Family of 5 Lives on $30,000 a Year in the Bronx
To help his family, Germel Younger has become a professional caregiver, but the pay barely covers their expenses.
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John Greally @greally.bsky.social · 13/09/2026
One week left to register, Workshop Transcriptional memory in health and disease: www.unia.es/estudios-y-a... 15 speakers, plus only 50 participants, 3 days of sharing of insights and ideas with leaders in the field.
unia.es
Workshop Transcriptional memory in health and disease
The idea that cells remember past states to prepare their future endeavors has split into two parallel languages that rarely converse. On one side, chromatin epigenetics defines inheritance through th...
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John MD @jwbelmon.bsky.social · 12/09/2026
Probability of Necessity www.medrxiv.org/content/10.6... among people who had the variant and developed the disease, the probability that the disease would not have occurred if the didn't have the variant. Low penetrance variants can have a high PN.
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John Greally @greally.bsky.social · 12/09/2026
This is the poem highlighted among the gifts from the Irish to the US president today. Ceasefire by Michael Longley. Beautiful. Brings tears to the eyes. youtu.be/PAxNRtTqDLI
youtu.be
Poet Michael Longley reading his poem "Ceasefire".
YouTube video by UCD Library Special Collections
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John Greally @greally.bsky.social · 10/09/2026
Thanks to @jkresovich.bsky.social for hosting me at @moffittnews.bsky.social, where I got to chat with colleagues about how we study ‘epigenetics’ in human diseases. Everything from cellular reprogramming to cell fate to functional non-coding variants. Jake looks ready to meet the challenges!
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John Greally @greally.bsky.social · 08/09/2026
Congrats to my wife @drgmcginty.bsky.social, who ends up leading everything in which she gets involved! news.weill.cornell.edu/news/2026/09...
news.weill.cornell.edu
Dr. Geraldine McGinty Named Executive Vice Dean of Weill Cornell Medicine
Dr. Geraldine McGinty, an esteemed academic healthcare leader and radiologist, has been appointed executive vice dean of Weill Cornell Medicine, effective Sept. 8.
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John Greally @greally.bsky.social · 05/09/2026
Disappointing but not the end of the road, good overview at @statnews.com After failure of Angelman syndrome drug, experts see hope in other experimental therapies www.statnews.com/2026/09/04/a... via @statnews.com
statnews.com
After failure of Angelman syndrome drug, experts see hope in other experimental therapies
After the failure of an experimental drug for Angelman syndrome, experts cautioned that there is still reason to think similar experimental medicines can succeed.
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The Jackson Laboratory @jax.org · 03/09/2026
A JAX-led study published today in @cellpress.bsky.social of more than 5,000 people is challenging long-held assumptions about cerebral palsy genetics. 🧬🧪
jax.org
Cerebral palsy might be a collection of symptoms, not its own disease
A JAX-led study of more than 5,000 people is challenging long-held assumptions about cerebral palsy genetics.
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John Greally @greally.bsky.social · 28/08/2026
Very proud of @einsteinmededu.bsky.social MSTP student Chynna Smith, just awarded a 2026-2027 ASHG @geneticssociety.bsky.social Scholarship. Chynna is a superstar in the making, working on a polycreodism model of osteoporosis. www.ashg.org/membership/a... Congratulations Chynna!
ashg.org
Human Genetics Scholars
ASHG in partnership with NHGRI, Biogenand Roche are pleased to recognize this year’s Scholars.
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John Greally @greally.bsky.social · 26/08/2026
Universally adored. Dolly Parton, on holiday, stops into Páidí O Sé’s pub in Ventry, he gives her his prized All Ireland GAA jersey, and she sings unrehearsed with Steve Cooney (around 6:35). Every time he added a flourish she looked over her shoulder with appreciation. youtu.be/2qXFoNrqi3Y?...
youtu.be
Dolly Parton in Paídi Ó Sé's Pub
YouTube video by paidiosekerry
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John Greally @greally.bsky.social · 25/08/2026
Now open access: www.annualreviews.org/content/jour...
annualreviews.org
Understanding the Role of Functional Noncoding Variation in Human Diseases with Lessons from Immunity
The advent of next-generation sequencing has expanded our understanding of the genotypic, pathobiological, and phenotypic spectrum of human disease, helping to inform more personalized patient care. C...
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🌈Tyranny🫧Sparkles🏳️‍🌈 @tyranny.sparklenoise.com · 25/08/2026
Dolly Parton with Keith Haring in 1985, incredible woman and supporter of LGBTQ people for decades going back to a time when few others dared.
Black and white photo of Dolly Parton with gay artist Keith Haring.
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John Greally @greally.bsky.social · 15/08/2026
Just lovely. Horse racing on Omey Island in Connemara. #Homesick www.nytimes.com/2026/08/15/w...
nytimes.com
Where Future Champions Race Against the Tide
An uninhabited Irish island fills up one day each summer for a treasured amateur horse race in which young jockeys ride across the shifting sands.
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John Greally @greally.bsky.social · 13/08/2026
Really looking forward to participating in this workshop: Transcriptional Memory in Health and Disease (if only because they were courageous enough not to call it 'Epigenetics' in Health and Disease) Great speaker lineup, workshop format, limited to ≤50 participants www.unia.es/estudios-y-a...
unia.es
Workshop Transcriptional memory in health and disease
The idea that cells remember past states to prepare their future endeavors has split into two parallel languages that rarely converse. On one side, chromatin epigenetics defines inheritance through th...
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John Greally @greally.bsky.social · 13/08/2026
I like papers that look simultaneously thoughtful and useful, nice work from Alex Ioannidis and colleagues Multi-ancestry admixture mapping reveals ancestry-associated disease loci in the UK Biobank medRxiv. posted 10 August 2026, 10.64898/2026.08.06.26359859 medrxiv.org/content/earl...
medrxiv.org
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Betty C. Jung @bettycjung.bsky.social · 12/08/2026
American Academy of Pediatrics This week’s announcement from federal officials instills unnecessary fear and uncertainty when it comes to childhood vaccines that have been thoroughly studied for decades.
bit.ly
AAP: Executive order to reduce childhood vaccines unscientific, dangerous
A new executive order reduces and spaces out recommended childhood vaccines at a time when measles is at a 35-year high and children are returning to school.
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Tuuli Lappalainen @tuuliel.bsky.social · 06/08/2026
Two weeks left to apply!
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Harmit Singh Malik @harmitmalik.bsky.social · 06/08/2026
Come be our colleague. I have been in this Division for 27 years (4 as a postdoc and 23 as a PI). It is an amazing place to work, collaborate, and be inspired. If you are applying to be an Assistant or Associate Professor this Fall, don't miss this deadline.
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John Greally @greally.bsky.social · 04/08/2026
I just realised that a couple of lovely people left 5-star reviews on Amazon for my book. I would like it to be known that neither of them was me. Thank you both, very kind of you. www.amazon.com/Epigenetics-... #epigenetics
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c0nc0rdance @c0nc0rdance.bsky.social · 01/08/2026
The headlines are still covering the cyclosporiasis outbreak from lettuce, but let's talk about a different summer, long ago. The headlines in Bavaria would have called it "summer diarrhea" & it was killing babies. Enter our hero, Professor Theodor Escherich of the Julius Hospital, Würzburg.
Signed portrait of Theodor Escherich, MD (1857-1911). Dr. Escherich was a German-Austrian pediatrician, best known for his discovery of the Escherichia coli bacterium
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💉Josh Rubin, MD @drsandman11.medsky.social · 31/07/2026
All due respect, if you didn’t look like this in the spring of 2020, I don’t really care about your opinion of Dr Fauci
3/2020: me in the ICU about to intubate a COVID patient for the first time
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John Greally @greally.bsky.social · 26/07/2026
The Sam Maguire cup is going to Mayo for the first time in 75 years. A huge moment for everyone from Mayo, the curse is broken, and what a performance by the Mayo team against a formidable Kerry side. Congratulations Mayo!
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REMALONE @ipasa.bsky.social · 22/07/2026
I have to admit that I didn’t know, and I even thought the Spanish player Cucurella’s look was quite original, when it comes to his hair, but I was unaware of this: If he let his hair grow , it’s so that his autistic son can easily recognize him when he watches him on TV. Truly, this Spanish team ❤️
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John Greally @greally.bsky.social · 22/07/2026
Hopefully this will provide a free link to a beautiful piece today by @fotoole.bsky.social (Support your local news media) archive.is/202607210554...
archive.is
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John Greally @greally.bsky.social · 22/07/2026
I should post another summary of something from my book. Any requests? I was thinking of an overview about DNA methylation, but open to other ideas. www.cshlpress.com/default.tpl?...
cshlpress.com
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Bongo @ghostofthewoods.bsky.social · 19/07/2026
New NJ law criminalizes interference with trans healthcare share.google/xT0wTeUXv9Bf... Some good news!
share.google
New Jersey makes it illegal to interfere with reproductive or gender-affirming healthcare
The law makes it a fourth-degree crime to harass or harm patients and healthcare providers, staff, or volunteers or block them from entering a facility that provides reproductive care, including servi...
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Oni Blackstock, MD MHS @oniblackstock.bsky.social · 16/07/2026
Very cool. NYC has a map for locating sites providing free N95 masks.
google.com
Mask Distribution Sites - Google My Maps
In response to the wildfire smoke, free masks will be available at the listed locations.
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John Greally @greally.bsky.social · 12/07/2026
You Can Know Too Much About Your Genes Genetic testing saves lives. It can also complicate them. By Elizabeth Bruenig @theatlantic.com www.theatlantic.com/ideas/2026/0...
theatlantic.com
You Can Know Too Much About Your Genes
Genetic testing saves lives. It can also complicate them.
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Shoumita Dasgupta, PhD @profdasgupta.bsky.social · 08/07/2026
“I don’t think people hoping to benefit public health by sharing their genetic data [All of Us] were really thinking that that’s the kind of company [Palantir] that would be handling their information.” -KHasson of @geneticsandsociety.bsky.social www.motherjones.com/politics/202...
motherjones.com
Palantir has a hand in NIH's most ambitious health initiative
The defense tech firm's work with public health data has largely flown under the radar.
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Jennifer Raff @jenniferraff.bsky.social · 25/06/2026
Friends, my husband @colinmcroberts.bsky.social is running for Congress and is the only candidate in the race who advocates abolishing ICE. He could use your support in this straw poll if you’re willing and on Facebook! www.facebook.com/share/1BDVhz...
facebook.com
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John Greally @greally.bsky.social · 22/06/2026
A small World Cup story in NYC. I saw three women sitting on a bench on Avenue A yesterday evening wearing Cape Verde jerseys. They were looking anxious. No TV nearby, no phones out. I thought "I'm not going to meet any other Cape Verde fans" so I stopped, said "Cape Verde" and clapped my hands
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Theresa Kim, PhD, MS @tyk314.net · 17/06/2026
#NIH has published the new Parent #F99/K00 #predoctoral to #postdoctoral award. The first due date is August 8, 2026. Please see the website to determine eligibility and submission dates. #sciencesky #medsky #funding
files.simpler.grants.gov
PA-27-037: Predoctoral to Postdoctoral Transition Award (Parent F99/K00 - Clinical Trial Not Allowed)
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John Greally @greally.bsky.social · 15/06/2026
The story to date of the @newyorkcrd.bsky.social, as told by the Einstein Innovation Group. Highlighting partners at @genedx.bsky.social, @pacbio.bsky.social, n-Lorem, @jax.org/NYSCF and NORD. aecomeig.substack.com/p/einstein-i...
aecomeig.substack.com
Einstein Innovators (Part 3: Dr. Xiao Peng, Dr. John Greally, and The New York Center for Rare Disease)
By Noah Jacobs, Edited by Jacob Kudria
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John Greally @greally.bsky.social · 14/06/2026
I love this picture -- this is what #NYC celebrating the Knicks' win last night looks like. So much captured in this image. static01.nyt.com/images/2026/... Photo credit Lexi Parra @nytimes.com
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Rav @rvbdrm.com · 14/06/2026
New Yorkers singing Empire State of Mind
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Pablo Navarro @pablonavarrolab.bsky.social · 03/06/2026
Epigenetics means different things for different people. In this workshop we will discuss two major views anchored on transcriptional memory: chromatin vs networks. Come and share with us our excitement for the topic and the magnificent place, the Andalusian Baeza. urldefense.com/v3/__https:/...
urldefense.com
Workshop Transcriptional memory in health and disease
The idea that cells remember past states to prepare their future endeavors has split into two parallel languages that rarely converse. On one side, chromatin epigenetics defines inheritance through th...
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Stardust 🌏🎬 @stardustbluepr.com · 11/06/2026
Incredible!! 💥🏀💥🏀💥🏀💥🏀💥🏀💥 The Knicks FULL 29 Point Comeback! Go Knicks!! 💥🏀💥🏀💥🏀💥🏀💥🏀💥
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John Greally @greally.bsky.social · 11/06/2026
I know the answer to this one: >It all depends on who pays for it. www.nytimes.com/2026/06/11/s...
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John Greally @greally.bsky.social · 10/06/2026
A reverse take on ‘Immigrants, we get the job done’ A healthy antidote to some of the X-driven poison circulating at present www.irishtimes.com/ireland/soci...
irishtimes.com
Immigrants make higher fiscal contribution than Irish-born, ESRI study finds
Separate study found ‘no general pattern’ of immigrants being more likely to be in receipt of welfare payments
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Lara Krüger @lara-kruger.bsky.social · 09/06/2026
📢 We are looking for a Junior Group Leader to join us at @institutcurie.bsky.social! Having joined the department just over a year ago, I can honestly say that it is an exceptionally stimulating and supportive scientific environment, filled with outstanding colleagues — all in the heart of Paris.
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David Landeira @davidlandeira.bsky.social · 08/06/2026
Excited to announce the International Workshop "Transcriptional memory in health & disease" in Baeza (Spain) this Oct 20-22! Discover how chromatin & networks encode cellular memory with top speakers. unia.es/estudios-y-a... pic.x.com/fjhBUrtRgb
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Mayor Zohran Kwame Mamdani @mayor.nyc.gov · 06/06/2026
Here's what New Yorkers can do: Sign up for emergency alerts by texting NOTIFYNYC to 692-692. Use caution if you're traveling. If flooding occurs, move to higher ground immediately. Check on your neighbors, especially seniors and those who may need extra support.
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John Greally @greally.bsky.social · 06/06/2026
Montefiore getting behind the Knicks! @einsteinmededu.bsky.social
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John Greally @greally.bsky.social · 05/06/2026
Oh great. www.nytimes.com/2026/06/04/s...
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Aylwyn Scally @aylwyn-scally.bsky.social · 28/05/2026
Postdoctoral job announcement: come to Cambridge and work on population genetic modelling with environmental and ancient DNA, jointly with @gamzeandgursoy.bsky.social and me. Details at www.jobs.cam.ac.uk/job/55580/ - applications by June 16th.
jobs.cam.ac.uk
Research Associate in Population Genetics Modelling and Environmental DNA (Fixed Term) - Job Opportunities - University of Cambridge
Research Associate in Population Genetics Modelling and Environmental DNA (Fixed Term) in the Department of Applied Mathematics and Theoretical Physics at the University of Cambridge.
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John Greally @greally.bsky.social · 03/06/2026
This should be great, gorgeous venue, outstanding speakers, workshop format. Health as the focus, a different kind of discussion needed. And nice that they used "Transcriptional memory" as opposed to "epigenetics". Workshop: Transcriptional memory in health and disease www.unia.es/estudios-y-a...
unia.es
Workshop Transcriptional memory in health and disease
The idea that cells remember past states to prepare their future endeavors has split into two parallel languages that rarely converse. On one side, chromatin epigenetics defines inheritance through th...
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