Sign in

Fred Hutch Basic Sciences Division

@basicsci.fredhutch.org
1.1K followers 719 following 149 posts

Making Foundational Discoveries @fredhutch.org fredhutch.org/basicsciences

PostsRepliesMedia
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 25/09/2026
Today is #ResearchAdministratorsDay! We thank our Research Administrators for their vital role in advancing Basic Sciences. From managing labs and funding to solving various issues, our division's success is thanks to their contributions every day.
Basic Sciences Research Admin Team
030
Reposted by Fred Hutch Basic Sciences Division
Harmit Singh Malik @harmitmalik.bsky.social · 23/09/2026
Then and Now: The Rapid Evolution of Harmit Malik www.the-scientist.com/then-and-now...
the-scientist.com
Harmit Malik Dives Into Viral Evolution and Speciation | The Scientist
Fascinated by evolution and driven by curiosity, Malik studies everything from viruses to Drosophila and, like his research subjects, is constantly reinventing himself.
58921
Reposted by Fred Hutch Basic Sciences Division
Harmit Singh Malik @harmitmalik.bsky.social · 21/09/2026
Thanks to the generosity of the Bezos Family Foundation, @basicsci.fredhutch.org is excited to announce a new search to recruit a Bezos Family Distinguished Scholar : apply.interfolio.com/193655
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
13730
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 18/09/2026
The 2026 Basic Sciences Retreat is today! Excited for talks from faculty, the poster session, meeting incoming students, and the scavenger hunt. Can’t wait to see everyone there and hear about all the latest research happening in the division!
010
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 17/09/2026
“Widespread neuronal mRNA recoding by regulated stop codon readthrough in Drosophila” We have a special guest seminar today! Dr. Lynn Cooley is joining us from @yaleschoolofmed.bsky.social to share her latest discoveries. For all @FredHutch.org colleagues, don’t miss a great talk in Pelton at 11!
Lynn Cooley, PhD
C.N.H. Long Professor of Genetics
Yale University School of Medicine
 
Title: “Widespread neuronal mRNA recoding by regulated stop codon readthrough in Drosophila”
 
11:00 AM on Thursday, September 17, 2026
Pelton, Weintraub Building, Fred Hutch
020
Reposted by Fred Hutch Basic Sciences Division
Fred Hutch @fredhutch.org · 16/09/2026
An analysis of more than 60,000 #RSV sequences from around the world found that viral variants associated with resistance to current RSV prevention tools remain rare, according to a study from the @jbloomlab.bsky.social published today in @nature.com. bit.ly/3Tb2tw5
bit.ly
Study supports effectiveness of RSV preventive antibody treatments for infants and provides new way to monitor viral resistance
A study published in the journal Nature of more than 60,000 RSV sequences found resistance-associated variants to two monoclonal antibody treatments are rare and provides a roadmap to help guide the d...
032
Reposted by Fred Hutch Basic Sciences Division
Fred Hutch @fredhutch.org · 08/09/2026
We are excited to announce this year's Stream for Fred Hutch Ambassadors! Each ambassador shows a commitment to growing the program and believe in the mission of Fred Hutch. They are all creators, fundraisers, and community builders.
Returning Stream for Fred Hutch Ambassadors:
Lance Icarus
PoisonHearrt
Sciants_Streams
LadyJBay
Garatsu72
New Stream for Fred Hutch Ambassadors:
CarloMTG
Starrelight
AlchemistJoker
SupremeDoom56
PawsitivelyStitched
Violaycious
11211
Reposted by Fred Hutch Basic Sciences Division
Fred Hutch @fredhutch.org · 04/09/2026
Fred Hutch is at #PAXWest this weekend! Stop by our Stream for Fred Hutch booth in the Arch Building skybridge lobby to learn how you can harness the power of your community to save lives and make breakthrough discoveries in cancer and infectious disease. bit.ly/4gRchDy
1105
Reposted by Fred Hutch Basic Sciences Division
Fred Hutch @fredhutch.org · 04/09/2026
🔬 Fred Hutch Cancer Center is hiring an Assistant or Associate Professor in the Basic Sciences Division @basicsci.fredhutch.org. Join a world-class research community in Seattle and help advance discoveries in fundamental biology. Apply: apply.interfolio.com/190640
1129
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 03/09/2026
Bring bold ideas and new directions to our collegial research community in Seattle. @FredHutch.org’s Basic Sciences Division is hiring an Assistant/Associate Professor. Apply by Oct 15. apply.interfolio.com/190640
apply.interfolio.com
Apply - Interfolio
010
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 01/09/2026
Want a window into fundamental science @fredhutch.org? Subscribe to our upcoming Basic Sciences newsletter for research highlights, community news, and more: eloqua.fredhutch.org/LP=326
eloqua.fredhutch.org
Basic Sciences Newsletter Subscription
000
Reposted by Fred Hutch Basic Sciences Division
HHMI @hhmi-science.bsky.social · 28/08/2026
Antibiotic resistance isn't just a genetic problem; it's ecological. New research from #HHMIInvestigator Harmit Malik & co shows that when a dangerous bacterium shares space w/a common fungus, it can be pushed toward resistance it wouldn't develop alone — but with a built-in weakness bit.ly/4g1jLnZ
Photo of Harmit Malik
Credit: Fred Hutch Cancer Center
15113
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 31/08/2026
Big breakthroughs often start with a single bold idea in a basic science lab. Invest in the postdocs @fredhutch.org Basic Sciences whose discoveries can change how we prevent, treat, and cure disease: secure.fredhutch.org/goto/basic-f...
secure.fredhutch.org
Training the Next Generation of Basic Scientists
Help Fred Hutch Cancer Center advance innovative research. Donate today!
010
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 27/08/2026
Science starts with curiosity. Stay connected to the researchers, ideas, and discoveries @FredHutch.org Basic Sciences—subscribe to our upcoming newsletter: eloqua.fredhutch.org/LP=326
eloqua.fredhutch.org
Basic Sciences Newsletter Subscription
010
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 26/08/2026
Postdocs in @FredHutch.org’s Basic Sciences Division are asking the fundamental questions that lead to lifesaving advances. Help fuel their training and research today: secure.fredhutch.org/goto/basic-f...
secure.fredhutch.org
Training the Next Generation of Basic Scientists
Help Fred Hutch Cancer Center advance innovative research. Donate today!
011
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 24/08/2026
Join @FredHutch.org's Basic Sciences Division as an Assistant or Associate Professor and help shape the future of fundamental biology. We welcome applicants whose work will complement, extend, or bring new directions to the division. apply.interfolio.com/190640
apply.interfolio.com
Apply - Interfolio
022
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 21/08/2026
Curiosity-driven basic science powers tomorrow’s cancer breakthroughs. Support postdocs @fredhutch.org Basic Sciences as they pursue bold ideas in the lab: secure.fredhutch.org/goto/basic-f...
secure.fredhutch.org
Training the Next Generation of Basic Scientists
Help Fred Hutch Cancer Center advance innovative research. Donate today!
040
Reposted by Fred Hutch Basic Sciences Division
Fred Hutch @fredhutch.org · 16/08/2026
Let cancer eat cake. 🍰 A Fred Hutch study led by @lucasbsullivan.bsky.social finds that feeding NRF2-mutated tumors too much of a nutrient they crave makes them vulnerable to slower growth and cell death. bit.ly/45Yx9Ua
bit.ly
Let cancer eat cake
Fred Hutch cancer metabolism expert Dr. Lucas Sullivan discovered that feeding NRF2-mutated tumors too much of a nutrient they crave makes them vulnerable to slower growth and cell death, a vulnerabil...
072
Reposted by Fred Hutch Basic Sciences Division
Fred Hutch @fredhutch.org · 15/08/2026
🔬 Fred Hutch Cancer Center is hiring an Assistant or Associate Professor in the Basic Sciences Division @basicsci.fredhutch.org. Join a world-class research community in Seattle and help advance discoveries in fundamental biology. Apply: apply.interfolio.com/190640
02322
Reposted by Fred Hutch Basic Sciences Division
Molecular & Cellular Biology Graduate Program @mcbseattle.bsky.social · 14/08/2026
Happening TODAY - Jodiene Johnson's defense! Title: Determining a mechanism for the synthetic lethal interaction between the DNA repair proteins BRCA2 and SCAI Lab: Adeyemi Lab, FH When: 11:00 a.m. PDT Where: FH O'Mack Suite (Steam Plant Building) & Zoom (email mcb@uw.edu for link)
Screenshot of defense announcement flyer for Jodiene Johnson. Flyer includes details such as title, date, time, and location of defense.
011
Reposted by Fred Hutch Basic Sciences Division
Harmit Singh Malik @harmitmalik.bsky.social · 13/08/2026
MxA is one of the broadest antiviral proteins mammals make. It’s a big reason most bird flu strains never get a foothold in people. The rare ones that succeed have learned to dodge it. How MxA actually recognizes viral targets at the molecular level is unknown for a bunch of technical reasons.
25923
Reposted by Fred Hutch Basic Sciences Division
Sanjay Srivatsan @sanjaysrivatsan.bsky.social · 11/08/2026
A new blog post thinking through the parallels between protein structure prediction and virtual cell efforts. Many of our current approaches to collect data to build a virtual cell model lack the abstraction that links measurement and function. t.co/4sPSMaLWLL
Acknowledgement: Illustration by David S. Goodsell, RCSB Protein Data Bank and the Scripps Research Institute. doi: 10.2210/rcsb_pdb/goodsell-gallery-050

Kinetochores separate chromosomes when eukaryotic cells divide. This illustration shows a yeast kinetochore (green) attached to a disassembling microtubule (blue). Chromatin is shown at upper right with DNA in yellow and histones in orange.
163
Reposted by Fred Hutch Basic Sciences Division
Harmit Singh Malik @harmitmalik.bsky.social · 06/08/2026
Come be our colleague. I have been in this Division for 27 years (4 as a postdoc and 23 as a PI). It is an amazing place to work, collaborate, and be inspired. If you are applying to be an Assistant or Associate Professor this Fall, don't miss this deadline.
2163151
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 05/08/2026
Join @FredHutch.org's Basic Sciences Division as an Assistant or Associate Professor and help shape the future of fundamental biology. We welcome applicants whose work will complement, extend, or bring new directions to the division.
apply.interfolio.com
Apply - Interfolio
02829
Reposted by Fred Hutch Basic Sciences Division
Molecular & Cellular Biology Graduate Program @mcbseattle.bsky.social · 31/07/2026
Join us for Jodiene Johnson's defense! Title: Determining a mechanism for the synthetic lethal interaction between the DNA repair proteins BRCA2 and SCAI Lab: Adeyemi Lab, FH When: Friday, August 14, 11:00 a.m. PDT Where: FH O'Mack Suite (Steam Plant Building) & Zoom (email mcb@uw.edu for link)
Screenshot of defense announcement flyer for Jodiene Johnson. Flyer includes details such as title, date, time, and location.
011
Reposted by Fred Hutch Basic Sciences Division
Harmit Singh Malik @harmitmalik.bsky.social · 21/07/2026
Gabriel Spitzer (@kuow.org) visited our lab to learn about our work to use evolutionary principles to supercharge innate immunity to (hopefully) deploy it in the face of viral infections. Gabriel is a masterful storyteller and would recommend listening to his ‘Pocket Science’ series (each ~12 min)
2257
Reposted by Fred Hutch Basic Sciences Division
Jeremy Hollis @jeremyahollis.bsky.social · 21/07/2026
Last Wednesday I had the immense privilege of defending my PhD dissertation @fredhutch.org @basicsci.fredhutch.org. The last 6 years in Seattle have been the most joyous of my life, and I am so grateful to have been surrounded by amazing people that made this not only possible, but wonderful! 1/
7939
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 22/07/2026
Dr. @harmitmalik.bsky.social chats with Gabriel Spitzer on Pocket Science from @kuow.org where he discusses his lab's work in Basic Sciences @FredHutch.org using the genetic echoes of long-dead viruses to help pinpoint defenses against whatever virus comes next.
kuow.org
Pocket Science
Discovery is happening all around Seattle… if you know where to look.
040
Reposted by Fred Hutch Basic Sciences Division
Molecular & Cellular Biology Graduate Program @mcbseattle.bsky.social · 20/07/2026
Join us for Emily Teets’s (@eteets.bsky.social ) dissertation defense! Title: Investigating the role of glial pruning in Parkinson's Disease Lab: Singhvi Lab, FH When: Monday, August 3, 1:00 p.m. PDT Where: FH Pelton Auditorium (Weintraub Building) & Zoom (email mcb@uw.edu for link)
Screenshot of announcement flyer for Emily Teets's defense containing information including title, location, date, and time.
011
Reposted by Fred Hutch Basic Sciences Division
Fred Hutch @fredhutch.org · 20/07/2026
Our immune systems have evolved to overcome all kinds of flus, plagues and poxes, but the process of adaptation is slow. @basicsci.fredhutch.orgs' @harmitmalik.bsky.social looks to find ways to put evolution into overdrive to fight future diseases. 🎧 Listen to @kuow.org's Pocket Science for more.
omny.fm
An evolutionary arms race - Pocket Science
Gabriel Spitzer talks to Harmit Malik about using the remains of dead viruses that have built up in our bodies to create new variants to target future viruses.
031
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 16/07/2026
Congratulations to Dr. Steve Hahn on being elected to the Washington State Academy of Sciences! A well-deserved recognition of his scientific leadership, mentorship, and contributions to advancing science in Washington.
washacad.org
New Members Elected to Washington State Academy of Sciences - Washington State Academy of Sciences
SEATTLE, WA – The Washington State Academy of Sciences (WSAS) announced today the election of 30 new members in recognition of their outstanding record of scientific and technical achievement and…
020
Reposted by Fred Hutch Basic Sciences Division
Harmit Singh Malik @harmitmalik.bsky.social · 16/07/2026
The remarkable @jeremyahollis.bsky.social defended his PhD thesis on the evolutionary innovations and landscapes of integrin proteins from Melody Campbell & Malik labs today to a packed house @fredhutch.org @basicsci.fredhutch.org Jeremy is a force of nature & one of the kindest people I’ve ever met
3679
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 09/07/2026
“Scents and Sense-ability” We’re excited to have Dr. Denise Ferkey speaking at a special scientific seminar today at noon. For all our @FredHutch.org colleagues, don’t miss a great talk in the Sze East room of the Thomas Building!
010
Reposted by Fred Hutch Basic Sciences Division
Harmit Singh Malik @harmitmalik.bsky.social · 05/07/2026
Open science before it had a name: An interview with molecular biologist Steven Henikoff (who is not on social media) @fredhutch.org @basicsci.fredhutch.org @hhmi-science.bsky.social @natprot.nature.com www.springernature.com/gp/researche...
springernature.com
Open science before it had a name: An interview with molecular biologist Steven Henikoff | For Researchers | Springer Nature
Dr. Steven Henikoff shares his experiences of how sharing protocols enables other people to use a method you develop, and how this moves the
14716
Reposted by Fred Hutch Basic Sciences Division
Jeremy Hollis @jeremyahollis.bsky.social · 01/07/2026
This was nothing short of a delight to work on with an amazing set of collaborators. Forever grateful to @basicsci.fredhutch.org at @fredhutch.org for making science so accessible and joyous to do!
181
Reposted by Fred Hutch Basic Sciences Division
Harmit Singh Malik @harmitmalik.bsky.social · 01/07/2026
Jeremy Hollis’ detective story on centromeric histone chaperones (HJURP/Cal1) is now published after peer review with a few extra goodies. @jeremyahollis.bsky.social @nlehrbach.bsky.social @cbmoens.bsky.social @irinakitop.bsky.social @basicsci.fredhutch.org www.science.org/doi/10.1126/...
science.org
Remote homology and functional genetics unmask deeply preserved Scm3/HJURP orthologs in metazoans
Animals encode a rapidly evolving, essential cell cycle gene previously thought to be absent.
23011
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 30/06/2026
High schoolers doing chromatin profiling? @FredHutch.org's Dr. Steve Henikoff explains how open science tools are being used to teach the next generation of scientists. Interview with @springernature.com:
springernature.com
Open science before it had a name: An interview with molecular biologist Steven Henikoff | For Researchers | Springer Nature
Dr. Steven Henikoff shares his experiences of how sharing protocols enables other people to use a method you develop, and how this moves the
041
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 29/06/2026
Training the next generation of scientists is critical for future scientific and medical breakthroughs. The Basic Sciences Postdoctoral Fellowship Award was established by Dr. Steve Hahn to support outstanding postdocs at Fred Hutch Basic Sciences. Apply now:
fredhutch.org
Basic Sciences Postdoctoral Fellowship Award
The Basic Sciences Postdoctoral Fellowship Award was established in 2026 to honor and support outstanding postdoctoral trainees, based primarily on their initial postdoctoral work at Fred Hutch.
053
Reposted by Fred Hutch Basic Sciences Division
Journal of Cell Biology @jcb.org · 25/06/2026
When Neuroligin2 sticks around, #astrocytes take shape. Sneha Ray and Aakanksha Singhvi @singhvilabglia.bsky.social @basicsci.fredhutch.org discuss work from Sakers, @caglaeroglu.bsky.social et al. (rupress.org/jcb/article/...), in Spotlight: rupress.org/jcb/article/... #Neuroscience
041
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 24/06/2026
"When you work on methods, they're only really successful if someone else uses them." @FredHutch.org's Dr. Steve Henikoff on why open science has always been the best way to do research. A must-read interview with @SpringerNature.com:
springernature.com
Open science before it had a name: An interview with molecular biologist Steven Henikoff | For Researchers | Springer Nature
Dr. Steven Henikoff shares his experiences of how sharing protocols enables other people to use a method you develop, and how this moves the
010
Reposted by Fred Hutch Basic Sciences Division
Fred Hutch @fredhutch.org · 23/06/2026
Dr. @irinakitop.bsky.social, a senior staff scientist in the Basic Sciences Division at Fred Hutch, is the first winner of the Genetics Society of America Mentorship Award who isn’t a principal investigator or faculty member. Read more: bit.ly/4epmdnD
021
Reposted by Fred Hutch Basic Sciences Division
Harmit Singh Malik @harmitmalik.bsky.social · 22/06/2026
www.fredhutch.org/content/www/... Ladies and gentlemen... the amazing @irinakitop.bsky.social !
fredhutch.org
Fred Hutch senior staff scientist honored by Genetics Society of America
Dr. Irini Topalidou, a senior staff scientist at Fred Hutch Cancer Center, is the first winner of the Genetics Society of America Mentorship Award who isn’t a principal investigator or faculty member....
2679
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 22/06/2026
"Open science before it had a name." @FredHutch.org's Dr. Steve Henikoff has been doing it for 50+ years! Read @springernature.com how he helped shape modern genomics and pushed for more open scientific practices:
springernature.com
Open science before it had a name: An interview with molecular biologist Steven Henikoff | For Researchers | Springer Nature
Dr. Steven Henikoff shares his experiences of how sharing protocols enables other people to use a method you develop, and how this moves the
031
Reposted by Fred Hutch Basic Sciences Division
UW Medicine Newsroom @uwmnewsroom.bsky.social · 11/06/2026
Lee Hartwell, director/president emeritus @fredhutch who's @uwmedicine.bsky.social & Fred Hutch work on cell cycle regulators earned him a 2001 #NobelPrize, talks about the rise of yeast as a model organism in biology with The Scientist's Laura Tran
tinyurl.com
The Rise of Yeast as a Model Organism in Biology | The Scientist
Yeast’s emergence as a model organism reshaped scientific discovery in cell biology, genetics, and more.
021
Reposted by Fred Hutch Basic Sciences Division
Melody Campbell @melodygcampbell.bsky.social · 16/06/2026
Congrats to Adam Nguyen and Jeremy Hollis @jeremyahollis.bsky.social !!
071
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 26/05/2026
Today we're celebrating the achievements of three Basic Sciences Faculty! Dr. Jesse Bloom (@jbloomlab.bsky.social) for being elected to the @nasonline.org, Dr. Susan Parkhurst for being named a Fellow of @aaas.org, and Dr. Toshio Tsukiyama for being appointed to the Lycette Endowed Chair.
Please join us today in celebrating Jesse Bloom, Susan Parkhurst, and Toshi Tsukiyama for their recent awards with coffee and pastries on Tuesday, May 26th at 11am in the Weintraub Atrium!

Jesse Bloom
National Academy of Sciences
 
Susan Parkhurst
2025 Fellow of American Association for the Advancement of Science

Toshio Tsukiyama
David and Deborah Lycette Endowed Chair for Cancer Research


*Coffee and treats provided*

Looking forward to seeing you there!
140
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 15/05/2026
We have two great talks lined up for the final Friday Afternoon Seminars of the season! For everyone @FredHutch.org, join us at 4:00 in Pelton to hear about the latest discoveries from Yulong Su in the Eisenman Lab and Joy Chen in Human Biology’s @behnamnabet.bsky.social Lab.
the last Friday Afternoon Seminar (FAS) of the 2025/26 season, this Friday 5/15 at 4pm in Pelton.
 
Yulong Su, Eisenman Lab
Multiplexed and combinatorial mapping of MYC-MAX-MGA transcription factor network in 3D Genome
 
Joy Chen, Nabet Lab
Targeted degradation of translation initiation factor eIF1A
041
Reposted by Fred Hutch Basic Sciences Division
@PhysGenCenter @physgencenter.bsky.social · 28/04/2026
Last week's fantastic seminar by Prof. Harmit Malik, "Genetic Conflicts Drive The Unexpected Rapid Evolution Of Essential Chromatin Proteins", can now be viewed on CPGE's YouTube channel! youtu.be/VxSppXrqGfI #chromatin #genomics #evolution #northwestern #genomics #proteins #dna #fredhutch
youtu.be
Harmit Malik- Genetic Conflicts Drive The Unexpected Rapid Evolution Of Essential Chromatin Proteins
YouTube video by Center for Physical Genomics and Engineering
083
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 08/05/2026
This year we presented a special introduction to the Weintraub Award Symposium featuring colleagues of Dr. Hal Weintraub telling stories about what made Hal such an exceptional scientist, mentor, collaborator, and friend. You can watch it here:
vimeo.com
Harold M. Weintraub Graduate Student Award Symposium Introduction
This is "Harold M. Weintraub Graduate Student Award Symposium Introduction" by Fred Hutch Cancer Center on Vimeo, the home for high quality videos and the people who love them.
020
Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 08/05/2026
We are so incredibly excited to kick off the 2026 Weintraub Graduate Student Award Symposium today at 9 AM! It’s going to be a phenomenal day of talks and celebration of the outstanding achievements of the awardees.
We will be having our twenty-seventh annual Harold M. Weintraub Graduate Student Award Symposium this Friday, May 8th in Pelton Auditorium.
010