Reposted by Oded MayselessAlex Schier @schierlab.bsky.social · 08/09/2026The first Danionella paper from the lab. Danionella cerebrum is transparent, so you can see all of the internal organs. But what sensory information are the organs sending to the brain? In our new preprint, Emily Bayer wanted to find out. 1/4 www.biorxiv.org/content/10.6... 18134
Reposted by Oded MayselessRainer Friedrich @rainerfriedrichlab.bsky.social · 08/09/2026Ultrastructural reconstruction of hundreds of neurons by volume EM revealed cell types and a precise glomerular organization in the zebrafish olfactory bulb. A heroic effort by Nila! Special thanks to Nila @michalwj.bsky.social and the whole team! www.biorxiv.org/content/10.6...biorxiv.orgDeep anatomical and ultrastructural classification of neurons in the zebrafish olfactory bulbNeuronal circuits in the olfactory bulb (OB) perform computations fundamental to pattern classification including a decorrelation and normalization of odor-evoked activity. These computations are medi... 0125
Reposted by Oded MayselessRainer Friedrich @rainerfriedrichlab.bsky.social · 08/09/2026Imaging of activity in the telencephalon of adult zebrafish moving through a virtual reality revealed amazingly precise, structured internal representations of spatial environments. And they get better over time! Great work by Kim! Thanks also to Sriram and Jan. www.biorxiv.org/content/10.6...biorxiv.orgDynamic cognitive representations in the dorsal pallium of adult zebrafishBrains rely on internal models of the world to interpret sensory input and to simulate the future. In the mammalian hippocampal-entorhinal network, environments are represented by cognitive maps that ... 1299
Reposted by Oded MayselessRainer Friedrich @rainerfriedrichlab.bsky.social · 08/09/2026New preprint by Tommaso: olfactory cortex (of zebrafish) represents not only odor information but also temporal context, and these multimodal representations are sharpened after learning. And check out Tommaso's new method for 2P imaging in awake adult zebrafish! www.biorxiv.org/content/10.6...biorxiv.orgJoint experience-dependent representations of odors and temporal context in the zebrafish homolog of piriform cortexIntelligent behavior requires experience-dependent internal representations of relevant information. We examined representational learning in telencephalic area pDp of adult zebrafish, the homolog of ... 12712
Reposted by Oded MayselessMadScientist @mads100tist.bsky.social · 29/08/2026Do you work with microscopy images and segment to quantify or track? Do you study cell biology? development? Gather round! Let me tell you about FOCUS-3D, a segmentation algorithm that is fast, accurate and can be used on any model. We used it here to study zebrafish development. 🧪 (thread)biorxiv.orgFOCUS‑3D: Robust, generalizable volumetric cell segmentation for three‑dimensional fluorescence microscopyUnderstanding how cells establish spatial organization within tissues is a fundamental question in life sciences. While modern three-dimensional fluorescence microscopy captures large-volume tissue ar... 1525183
Reposted by Oded MayselessAlex Schier @schierlab.bsky.social · 19/08/2026What regulates the urge to sleep? William Joo and colleagues identified brain regions that reflect how long mice have been awake. Strikingly, inhibiting one of these regions reduces sleep by 70%, without the major behavioral deficits associated with sleep deprivation. www.nature.com/articles/s41...nature.comWake-activated neuronal populations that regulate sleep drive - NatureWhole-brain activity mapping, targeted cell manipulations and electrophysiology in mice identify wake-activated neuronal populations that are crucial for sleep drive and can persistently red... 48631
Reposted by Oded MayselessHarmit Singh Malik @harmitmalik.bsky.social · 06/08/2026Come be our colleague. I have been in this Division for 27 years (4 as a postdoc and 23 as a PI). It is an amazing place to work, collaborate, and be inspired. If you are applying to be an Assistant or Associate Professor this Fall, don't miss this deadline. 2163151
Reposted by Oded MayselessBahl Lab @bahllab.bsky.social · 03/08/2026🚨New preprint doi.org/10.64898/2026.06.07.730682. We show that zebrafish larvae exhibit complex, internally generated, spontaneous behavioral patterns in the absence of stimuli. These dynamics can be described by a simple Markov process with transition probabilities that change over time. 6197
Reposted by Oded MayselessShawn Burgess @burgesslab.bsky.social · 30/07/2026Yet another #zebrafish genome update: We just updated our ZebrafishGenomics public datahub for the UCSC browser (available all the way at the bottom here: genome.ucsc.edu/cgi-bin/hgHu...). We added several useful tracks including:genome.ucsc.edu 1149
Reposted by Oded MayselessJohannes Felsenberg @felsenberg.bsky.social · 31/07/2026Finally out in @natneuro.nature.com! A forgotten memory isn't always gone. We show that forgotten memories persist as silent memory traces, can be recovered by reminders, and can even be reconstructed into false memories. Excited to finally share this work! www.nature.com/articles/s41...nature.comCreating true and false memories from forgotten information in Drosophila - Nature NeuroscienceForgotten memories in Drosophila persist as silent memory traces and can be recovered by reminder cues. Manipulating reminders can create false memories, showing that memory reconstruction flexibly in... 1214154
Reposted by Oded MayselessEmre Yaksi @emreyaksi.bsky.social · 17/07/2026🧠 A new paper from our lab is out! In this study, we explore how dorsal raphe nucleus (DRN) circuits modulate forebrain activity and behavior. www.nature.com/articles/s41...nature.comTopographically organized dorsal raphe activity modulates forebrain sensory-motor representations and contributes to defensive behaviors - Nature CommunicationsFunctional heterogeneity of dorsal raphe nucleus is not fully understood. Here authors show topographically organized sensory and locomotor responses from the zebrafish dorsal raphe and its forebrain ... 26621
Reposted by Oded MayselessAustin Seroka @austinseroka1.bsky.social · 06/07/2026We're excited to present a single-cell atlas of vertebrate cranial motor neuron development, the first story from my postdoctoral work in the Moens lab, up now on bioRxiv! 53116
Reposted by Oded MayselessTakashi Fukaya @fukayalab.bsky.social · 06/07/2026We have an open professor position at my institute, the Institute for Quantitative Biosciences, The University of Tokyo! www.iqb.u-tokyo.ac.jp/recruiting/2...iqb.u-tokyo.ac.jp 02522
Reposted by Oded Mayselessvoigtvision.bsky.social @voigtvision.bsky.social · 06/07/2026🚨 New Preprint! 🚨: A new method for quantifying #tissue #clearing and a next-get #lightsheet #Microscope - the #mesoSPIM ultra by Marko Pende, @jcregg.bsky.social, @murawalalab.bsky.social @mdibl.org & many more! Preprint: www.biorxiv.org/content/10.6... Github: github.com/mesoSPIM/mes... 32710
Reposted by Oded MayselessBahl Lab @bahllab.bsky.social · 05/07/2026We are excited to share our collaboration with @pheereynolds.bsky.social, Robert Hindges & team on retinal plasticity, now out in Neuron! This work shows how visual experience during early development changes the anatomical and functional properties of amacrine cells and ultimately behavior!cell.comEarly visual experience elicits cellular and functional plasticity in the retina and alters behaviorThe understanding of experience-dependent plasticity in the vertebrate retina is largely incomplete. Reynolds et al. discovered that raising animals in differently patterned visual environments change... 34120
Reposted by Oded MayselessEmre Yaksi @emreyaksi.bsky.social · 02/07/2026I am excited to announce the latest paper from our lab, published in Science ! In this study, we show that thalamocortical-like circuits in the zebrafish brain process sensory information hierarchically across topographically organized forebrain circuits.science.orgHierarchical sensory processing in zebrafish thalamocortical-like circuitsThalamocortical projections shape the functional regionalization and parallel sensory computations across the mammalian cortex. However, the principles of thalamocortical computations in non-mammalian... 1311837
Reposted by Oded MayselessFumi Kubo @fumikubo.bsky.social · 01/07/2026Happy to share our new paper published in @currentbiology.bsky.social! Using in vivo imaging of genetically defined zebrafish retinal ganglion cells (RGCs), we show that while some Satb2+ RGCs maintain stable functional identities during development, others undergo functional changes. 3132
Reposted by Oded MayselessJohn Tuthill @tuthill.bsky.social · 30/06/2026My department, Neurobiology and Biophysics at the University of Washington (nbio.uw.edu), is hiring a new tenure-track Assistant Professor, application deadline 09/30/26. It's a broad search — molecular to organismal, all of neuroscience/physiology/biophysics welcome. apply.interfolio.com/187735 110789
Reposted by Oded MayselessLoïc A. Royer 💻🔬🧪 @loicaroyer.bsky.social · 29/06/20261/ 🧬🔬 How does one cell become an entire animal? We can now film it in 3D 🐟, but turning those movies into accurate cell tracks is brutally hard. Enter our new #Kaggle challenge: $60K prize pool, to help crack 3D+time cell tracking at scale! 🧵👇 www.kaggle.com/competitions... @biohub.org 17941
Reposted by Oded Mayselesstahneema.bsky.social @tahneema.bsky.social · 28/06/2026Very excited to finally share my PhD! 🎉 Our paper, “Neuronal microexons modulate arousal via the cAMP-PKA-CREB pathway in zebrafish,” is now published in Science Advances. Many thanks to all of my co-authors, and especially to @mirimiam.bsky.social! 📄 www.science.org/doi/10.1126/...science.orgNeuronal microexons modulate arousal via the cAMP-PKA-CREB pathway in zebrafishLoss of the conserved splicing factor for neuronal microexons disrupts neuromodulatory signaling and drives hyperarousal. 085
Reposted by Oded MayselessMarc Dionne @marcsdionne.bsky.social · 25/06/2026We're hiring! The Department of Life Sciences at Imperial College London is seeking a new Assistant Professor in ecology, evolution, or environmental science. It's a great department with great students at a great university. www.imperial.ac.uk/jobs/search-...imperial.ac.ukDescriptionPlease note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment... 0712
Reposted by Oded MayselessPhoebe Reynolds @pheereynolds.bsky.social · 23/06/2026I’m very excited to share that our paper is now out in Neuron! 🎉 34114
Reposted by Oded MayselessBahl Lab @bahllab.bsky.social · 22/06/2026New paper out: www.cell.com/iscience/ful... Congratulations to our former PhD student @maxcapelle.bsky.social whose work reveals that the switch in light preference across zebrafish development is driven by a reweighting of three parallel visual processing pathways. Check out a short summary below! 13212
Reposted by Oded MayselessAlex Schier @schierlab.bsky.social · 17/06/2026Might cerebellar disinhibition underlie Restless Legs Syndrome symptoms? Will Joo found that loss of the RLS-associated gene meis1b perturbs locomotion in zebrafish by disinhibiting cerebellar output. www.sciencedirect.com/science/arti... 23410
Reposted by Oded MayselessLukas Anneser @lukas-anneser.bsky.social · 17/06/2026Congratulations! This was long in the making and the resulting data is quite beautiful. Definitely worth a read! 172
Reposted by Oded MayselessZebrafish Rock! @zebrafishrock.bsky.social · 17/06/2026🔗 to paper: www.biorxiv.org/content/10.6... 041
Reposted by Oded MayselessMadScientist @mads100tist.bsky.social · 16/06/2026Happy to have contributed to this mastodon of a paper about how the nose knows 🧪🐟 2162
Oded Mayseless @mayseless.bsky.social · 16/06/20261/11 Excited to share my postdoc work from @schierlab.bsky.social and Rainer Friedrich! 🐟👃 How does the brain decide whether an odor is good or bad? In larval zebrafish, we find that odor preference is reflected in spatially cohesive neuronal domains of the olfactory bulb. 🧵 26625
Reposted by Oded MayselessMadScientist @mads100tist.bsky.social · 16/03/2026It's out! Happy to present ITEC, a semi supervised algorithm with an extremely low error rate that can track cells in files of any size (think Terabytes!). We used it in many organisms, including zebrafish, to study how organs form and linked it to gene expression www.biorxiv.org/content/10.6... +🧪biorxiv.org 2019960
Reposted by Oded MayselessAlex Schier @schierlab.bsky.social · 12/03/2026Very happy to see this out. 👏 @yinanwan.bsky.social Bogdan Bintu and team. Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...science.orgWhole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesisGene expression patterns underlie development, but their systematic detection in whole embryos has remained elusive. We introduce a whole-embryo imaging platform using multiplexed error-robust fluores... 618780
Reposted by Oded MayselessPortugues Lab @portugueslab.bsky.social · 07/01/20261/6: New publication from the lab: “Plastic landmark anchoring in zebrafish compass neurons” by Ryosuke Tanaka (@ryosuketanaka.bsky.social) and Ruben is available here: rdcu.be/eX1L4rdcu.bePlastic landmark anchoring in zebrafish compass neuronsNature - Using two-photon microscopy with a panoramic virtual reality setup, how head direction cells in larval zebrafish integrate visual landmarks and optic flow to track orientation is revealed. 14822
Reposted by Oded MayselessInbal Shainer @ishainer.bsky.social · 18/12/2025Very proud to see our paper selected as one of Nature’s 2025 highlights! @johanneskappel.bsky.social @jlarsch.bsky.social @mpiforbi.bsky.social www.nature.com/articles/d41...nature.comAsteroids, antibiotics and ants: a year of remarkable scienceHighlights from News & Views published in 2025. 194
Reposted by Oded MayselessNature @nature.com · 11/12/2025“Up ’till now, we couldn’t detect it, because we didn’t look at the garbage cans of cells.” Yifat Merbl found a new trick of the immune system, and is part of Nature’s 10, a list of people who shaped science in 2025 go.nature.com/3XQWoUtgo.nature.comThis scientist found a new trick of the immune system by digging through cellular rubbishYifat Merbl is part of Nature’s 10, a list of people who shaped science in 2025. 04411
Reposted by Oded MayselessPortugues Lab @portugueslab.bsky.social · 24/11/2025(1/n) We are excited to share our new paper in Nature Communications, by Hagar Lavian (@hlavian.bsky.social) and team, revealing how the zebrafish brain integrates visual navigation signals! www.nature.com/articles/s41...nature.comVisual motion and landmark position align with heading direction in the zebrafish interpeduncular nucleus - Nature CommunicationsHow are various visual signals integrated in the vertebrate brain for navigation? Here authors show that different spatial signals are topographically organized and align to one another in the zebrafi... 35421
Reposted by Oded MayselessHagar Lavian @hlavian.bsky.social · 04/12/2025Very excited to share this thread on our recent paper! We show how Zebrafish integrate visual navigation signals in aligned topographic maps. Full thread below🧵 1258
Reposted by Oded MayselessShawn Burgess @burgesslab.bsky.social · 17/11/2025Folks, it is finally out! Our paper on T2T assemblies of the zebrafish genome is on BioRxiv: www.biorxiv.org/content/10.1...biorxiv.org 16830
Reposted by Oded MayselessStefan Luschnig @luschnig.bsky.social · 12/11/2025Job Alert! The Institute for Neuro- and Behavioural Biology at the Faculty of Biology @uni-muenster.de invites applications for a Full Professorship (W3) in “Systems Neuroscience” - Highly attractive research environment at the Multiscale Imaging Center. Apply by January 5th. See shorturl.at/VczFp 02734
Reposted by Oded MayselessOded Rechavi @odedrechavi.bsky.social · 06/11/2025IT'S HAPPENING! 💥 I'm psyched to launch the collaboration between @qedscience.bsky.social & @openrxiv.bsky.social @biorxivpreprint.bsky.social! Preprint + q.e.d = your science is out there, and anyone can appreciate it. Let's care about making discoveries, and not on “getting published” (1/3) 👇 712864
Reposted by Oded MayselessDavid Schoppik @schoppik.com · 02/11/2025Thread coming soon, but be the first to read the latest from @franziau.bsky.social! 1278
Reposted by Oded Mayselessnapari @napari.org · 21/10/2025You might have noticed lots of activity in the napari project recently! 🚀 We're grateful for a grant from CZI that's keeping us going, but grants don't last forever: we're trying to figure out sustainable long term funding. Read our blog post to find out how you can help: napari.org/island-dispa... 12817
Reposted by Oded MayselessSophie Caron @thecaronlab.bsky.social · 30/10/20251/ Hello Drosophila-philists and braino-maniacs! 👋🪰🧠🧪 The Caron lab has a new preprint, and it is about 🥁🥁🥁 democracy! Neuro-democracy, to be precise. So: drop EVERYTHING and listen up — a 🧶! www.biorxiv.org/content/10.1... 34218
Reposted by Oded MayselessHarvard_MCB @harvardmcb.bsky.social · 29/10/2025Catherine Dulac Named Xander University Professor 🧠 🧪🧬 #AcademicSky #higherEd www.mcb.harvard.edu/department/n... @dulaclab.bsky.social @rachellegaudet.bsky.social @neurovenki.bsky.social @naoshigeuchida.bsky.social @harvardbrainsci.bsky.social @hhmi.org @cryptogenomicon.bsky.socialmcb.harvard.eduCatherine Dulac Named Xander University Professor - Harvard University - Department of Molecular & Cellular BiologyMCB’s Catherine Dulac, Howard Hughes Medical Institute Investigator and renowned neuroscientist, has been appointed the Xander University Professor. Four Harvard scholars were recognized with appointm... 1288
Reposted by Oded MayselessSimon Fisher @profsimonfisher.bsky.social · 29/10/2025More than two decades have passed since we discovered that rare disruptions of the FOXP2 gene disturb development of proficient speech/language skills. Today we know of multiple FOXP genes that are directly implicated in distinct brain-related conditions with differences in symptoms & severity.🧪 1/n 26625
Reposted by Oded MayselessPawel Burkhardt @pawelburkhardt.bsky.social · 27/10/2025First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience Our latest in @natrevneuro.nature.com Link: rdcu.be/eMX3E @jeffcolgren.bsky.social @msarscentre.bsky.socialrdcu.beThe evolutionary origins of synaptic proteins and their changing roles in different organisms across evolutionNature Reviews Neuroscience - Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were... 4361139
Reposted by Oded MayselessMartin Haesemeyer @haesemeyerlab.bsky.social · 24/10/2025Out now in @currentbiology.bsky.social led by Kaarthik A Balakrishnan: We identify medullary circuits that represent the valence of thermal stimuli and control both long-term strategies of cold-avoidance and short term hot avoidance behaviors to enable thermoregulation. www.cell.com/current-biol...cell.comBehavioral and circuit principles of temperature gradient navigationBehavioral thermoregulation is critical for survival across animals. Balakrishnan and Haesemeyer discover that thermoregulatory behavior in larval zebrafish is organized into longer-term swim modes. T... 0139
Reposted by Oded MayselessMike Fainzilber @mfainzilber.bsky.social · 11/10/2025www.science.org/content/arti...science.orgPerfume scientists tweak cells into having ‘sense of smell’A study could transform the lab study of olfaction—and may challenge a Nobel-winning hypothesis 053
Reposted by Oded MayselessBen de Bivort @debivort.bsky.social · 08/10/2025Our new study modeling selection for (behavioral) variability has been covered in a lovely @genetics-gsa.bsky.social podcast featuring first author Shraddha Lall and @ecoevogal.bsky.social academic.oup.com/g3journal/ad...academic.oup.comFamily-based selection: an efficient method for increasing phenotypic variabilityThis article introduces a model comparing various selection regimes for increasing phenotypic variability. Individuals with the same genotype, reared in id 54016
Reposted by Oded MayselessRichard Benton @bentonlab.bsky.social · 06/10/2025Having personally sworn for years that insects don’t use GPCRs for odour detection, Suguru Takagi (@sugurutakagi.bsky.social) discovers that, in fact, they sometimes do … www.biorxiv.org/content/10.1...biorxiv.orgA GPCR signaling pathway in insect odor detectionOdor detection differs fundamentally in vertebrates, which use G protein-coupled receptors (GPCRs), and insects, which employ ion channels. Here, we report the first evidence for a GPCR defining tunin... 45529
Reposted by Oded MayselessVenki Murthy @neurovenki.bsky.social · 01/09/2025Thrilled to share this work, long time in the making! Carried through creatively by @siddjakes.bsky.social after initial design & piloting by @trackingskills.bsky.social, with help from @trackingactions.bsky.social. Modeling in collaboration with Massimo Vergassola & Nicola Rigolli.biorxiv.orgMice navigate scent trails using predictive policiesAnimals actively sense their environment to extract features of interest to guide behaviors. For mammals, odors are prominent environmental features which are sampled by active modulation of sniffing ... 112441
Reposted by Oded MayselessJanelia Research Campus @hhmijanelia.bsky.social · 26/08/2025📢We're #hiring Group Leaders! Apply to lead a lab at Janelia & advance biology using theory, computational modeling & machine learning. 🔹5-year renewable appointment 🔹Pioneer new tools & approaches 🔹Collaborate across disciplines Apply by Nov. 4👉 janelia.link/groupleader 06365