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Oded Mayseless

@mayseless.bsky.social
622 followers 419 following 36 posts

Postdoc in the @schierlab. Visiting scientist @RainerFriedri12. PhD @lab_oren @WeizmannScience. What is the molecular basis of good vs evil? #zebrafish #olfaction

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Reposted by Oded Mayseless
Alex Schier @schierlab.bsky.social · 08/09/2026
The first Danionella paper from the lab. Danionella cerebrum is transparent, so you can see all of the internal organs. But what sensory information are the organs sending to the brain? In our new preprint, Emily Bayer wanted to find out. 1/4 www.biorxiv.org/content/10.6...
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Rainer Friedrich @rainerfriedrichlab.bsky.social · 08/09/2026
Ultrastructural reconstruction of hundreds of neurons by volume EM revealed cell types and a precise glomerular organization in the zebrafish olfactory bulb. A heroic effort by Nila! Special thanks to Nila @michalwj.bsky.social and the whole team! www.biorxiv.org/content/10.6...
biorxiv.org
Deep anatomical and ultrastructural classification of neurons in the zebrafish olfactory bulb
Neuronal circuits in the olfactory bulb (OB) perform computations fundamental to pattern classification including a decorrelation and normalization of odor-evoked activity. These computations are medi...
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Rainer Friedrich @rainerfriedrichlab.bsky.social · 08/09/2026
Imaging of activity in the telencephalon of adult zebrafish moving through a virtual reality revealed amazingly precise, structured internal representations of spatial environments. And they get better over time! Great work by Kim! Thanks also to Sriram and Jan. www.biorxiv.org/content/10.6...
biorxiv.org
Dynamic cognitive representations in the dorsal pallium of adult zebrafish
Brains rely on internal models of the world to interpret sensory input and to simulate the future. In the mammalian hippocampal-entorhinal network, environments are represented by cognitive maps that ...
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Rainer Friedrich @rainerfriedrichlab.bsky.social · 08/09/2026
New preprint by Tommaso: olfactory cortex (of zebrafish) represents not only odor information but also temporal context, and these multimodal representations are sharpened after learning. And check out Tommaso's new method for 2P imaging in awake adult zebrafish! www.biorxiv.org/content/10.6...
biorxiv.org
Joint experience-dependent representations of odors and temporal context in the zebrafish homolog of piriform cortex
Intelligent behavior requires experience-dependent internal representations of relevant information. We examined representational learning in telencephalic area pDp of adult zebrafish, the homolog of ...
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MadScientist @mads100tist.bsky.social · 29/08/2026
Do you work with microscopy images and segment to quantify or track? Do you study cell biology? development? Gather round! Let me tell you about FOCUS-3D, a segmentation algorithm that is fast, accurate and can be used on any model. We used it here to study zebrafish development. 🧪 (thread)
biorxiv.org
FOCUS‑3D: Robust, generalizable volumetric cell segmentation for three‑dimensional fluorescence microscopy
Understanding how cells establish spatial organization within tissues is a fundamental question in life sciences. While modern three-dimensional fluorescence microscopy captures large-volume tissue ar...
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Alex Schier @schierlab.bsky.social · 19/08/2026
What regulates the urge to sleep? William Joo and colleagues identified brain regions that reflect how long mice have been awake. Strikingly, inhibiting one of these regions reduces sleep by 70%, without the major behavioral deficits associated with sleep deprivation. www.nature.com/articles/s41...
nature.com
Wake-activated neuronal populations that regulate sleep drive - Nature
Whole-brain activity mapping, targeted cell manipulations and electrophysiology in mice identify wake-activated neuronal populations that are crucial for sleep drive and can persistently red...
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Harmit Singh Malik @harmitmalik.bsky.social · 06/08/2026
Come be our colleague. I have been in this Division for 27 years (4 as a postdoc and 23 as a PI). It is an amazing place to work, collaborate, and be inspired. If you are applying to be an Assistant or Associate Professor this Fall, don't miss this deadline.
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Bahl Lab @bahllab.bsky.social · 03/08/2026
🚨New preprint doi.org/10.64898/2026.06.07.730682. We show that zebrafish larvae exhibit complex, internally generated, spontaneous behavioral patterns in the absence of stimuli. These dynamics can be described by a simple Markov process with transition probabilities that change over time.
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Shawn Burgess @burgesslab.bsky.social · 30/07/2026
Yet another #zebrafish genome update: We just updated our ZebrafishGenomics public datahub for the UCSC browser (available all the way at the bottom here: genome.ucsc.edu/cgi-bin/hgHu...). We added several useful tracks including:
genome.ucsc.edu
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Johannes Felsenberg @felsenberg.bsky.social · 31/07/2026
Finally out in @natneuro.nature.com! A forgotten memory isn't always gone. We show that forgotten memories persist as silent memory traces, can be recovered by reminders, and can even be reconstructed into false memories. Excited to finally share this work! www.nature.com/articles/s41...
nature.com
Creating true and false memories from forgotten information in Drosophila - Nature Neuroscience
Forgotten memories in Drosophila persist as silent memory traces and can be recovered by reminder cues. Manipulating reminders can create false memories, showing that memory reconstruction flexibly in...
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Emre Yaksi @emreyaksi.bsky.social · 17/07/2026
🧠 A new paper from our lab is out! In this study, we explore how dorsal raphe nucleus (DRN) circuits modulate forebrain activity and behavior. www.nature.com/articles/s41...
nature.com
Topographically organized dorsal raphe activity modulates forebrain sensory-motor representations and contributes to defensive behaviors - Nature Communications
Functional heterogeneity of dorsal raphe nucleus is not fully understood. Here authors show topographically organized sensory and locomotor responses from the zebrafish dorsal raphe and its forebrain ...
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Austin Seroka @austinseroka1.bsky.social · 06/07/2026
We're excited to present a single-cell atlas of vertebrate cranial motor neuron development, the first story from my postdoctoral work in the Moens lab, up now on bioRxiv!
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Takashi Fukaya @fukayalab.bsky.social · 06/07/2026
We have an open professor position at my institute, the Institute for Quantitative Biosciences, The University of Tokyo! www.iqb.u-tokyo.ac.jp/recruiting/2...
iqb.u-tokyo.ac.jp
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voigtvision.bsky.social @voigtvision.bsky.social · 06/07/2026
🚨 New Preprint! 🚨: A new method for quantifying #tissue #clearing and a next-get #lightsheet #Microscope - the #mesoSPIM ultra by Marko Pende, @jcregg.bsky.social, @murawalalab.bsky.social @mdibl.org & many more! Preprint: www.biorxiv.org/content/10.6... Github: github.com/mesoSPIM/mes...
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Bahl Lab @bahllab.bsky.social · 05/07/2026
We are excited to share our collaboration with @pheereynolds.bsky.social, Robert Hindges & team on retinal plasticity, now out in Neuron! This work shows how visual experience during early development changes the anatomical and functional properties of amacrine cells and ultimately behavior!
cell.com
Early visual experience elicits cellular and functional plasticity in the retina and alters behavior
The understanding of experience-dependent plasticity in the vertebrate retina is largely incomplete. Reynolds et al. discovered that raising animals in differently patterned visual environments change...
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Emre Yaksi @emreyaksi.bsky.social · 02/07/2026
I am excited to announce the latest paper from our lab, published in Science ! In this study, we show that thalamocortical-like circuits in the zebrafish brain process sensory information hierarchically across topographically organized forebrain circuits.
science.org
Hierarchical sensory processing in zebrafish thalamocortical-like circuits
Thalamocortical projections shape the functional regionalization and parallel sensory computations across the mammalian cortex. However, the principles of thalamocortical computations in non-mammalian...
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Fumi Kubo @fumikubo.bsky.social · 01/07/2026
Happy to share our new paper published in @currentbiology.bsky.social! Using in vivo imaging of genetically defined zebrafish retinal ganglion cells (RGCs), we show that while some Satb2+ RGCs maintain stable functional identities during development, others undergo functional changes.
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John Tuthill @tuthill.bsky.social · 30/06/2026
My department, Neurobiology and Biophysics at the University of Washington (nbio.uw.edu), is hiring a new tenure-track Assistant Professor, application deadline 09/30/26. It's a broad search — molecular to organismal, all of neuroscience/physiology/biophysics welcome. apply.interfolio.com/187735
NBIO department logo
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Loïc A. Royer 💻🔬🧪 @loicaroyer.bsky.social · 29/06/2026
1/ 🧬🔬 How does one cell become an entire animal? We can now film it in 3D 🐟, but turning those movies into accurate cell tracks is brutally hard. Enter our new #Kaggle challenge: $60K prize pool, to help crack 3D+time cell tracking at scale! 🧵👇 www.kaggle.com/competitions... @biohub.org
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tahneema.bsky.social @tahneema.bsky.social · 28/06/2026
Very excited to finally share my PhD! 🎉 Our paper, “Neuronal microexons modulate arousal via the cAMP-PKA-CREB pathway in zebrafish,” is now published in Science Advances. Many thanks to all of my co-authors, and especially to @mirimiam.bsky.social! 📄 www.science.org/doi/10.1126/...
science.org
Neuronal microexons modulate arousal via the cAMP-PKA-CREB pathway in zebrafish
Loss of the conserved splicing factor for neuronal microexons disrupts neuromodulatory signaling and drives hyperarousal.
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Marc Dionne @marcsdionne.bsky.social · 25/06/2026
We're hiring! The Department of Life Sciences at Imperial College London is seeking a new Assistant Professor in ecology, evolution, or environmental science. It's a great department with great students at a great university. www.imperial.ac.uk/jobs/search-...
imperial.ac.uk
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
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Phoebe Reynolds @pheereynolds.bsky.social · 23/06/2026
I’m very excited to share that our paper is now out in Neuron! 🎉
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Bahl Lab @bahllab.bsky.social · 22/06/2026
New paper out: www.cell.com/iscience/ful... Congratulations to our former PhD student @maxcapelle.bsky.social whose work reveals that the switch in light preference across zebrafish development is driven by a reweighting of three parallel visual processing pathways. Check out a short summary below!
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Alex Schier @schierlab.bsky.social · 17/06/2026
Might cerebellar disinhibition underlie Restless Legs Syndrome symptoms? Will Joo found that loss of the RLS-associated gene meis1b perturbs locomotion in zebrafish by disinhibiting cerebellar output. www.sciencedirect.com/science/arti...
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Lukas Anneser @lukas-anneser.bsky.social · 17/06/2026
Congratulations! This was long in the making and the resulting data is quite beautiful. Definitely worth a read!
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Zebrafish Rock! @zebrafishrock.bsky.social · 17/06/2026
🔗 to paper: www.biorxiv.org/content/10.6...
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MadScientist @mads100tist.bsky.social · 16/06/2026
Happy to have contributed to this mastodon of a paper about how the nose knows 🧪🐟
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Oded Mayseless @mayseless.bsky.social · 16/06/2026
1/11 Excited to share my postdoc work from @schierlab.bsky.social and Rainer Friedrich! 🐟👃 How does the brain decide whether an odor is good or bad? In larval zebrafish, we find that odor preference is reflected in spatially cohesive neuronal domains of the olfactory bulb. 🧵
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MadScientist @mads100tist.bsky.social · 16/03/2026
It's out! Happy to present ITEC, a semi supervised algorithm with an extremely low error rate that can track cells in files of any size (think Terabytes!). We used it in many organisms, including zebrafish, to study how organs form and linked it to gene expression www.biorxiv.org/content/10.6... +🧪
biorxiv.org
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Alex Schier @schierlab.bsky.social · 12/03/2026
Very happy to see this out. 👏 @yinanwan.bsky.social Bogdan Bintu and team. Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...
science.org
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis
Gene expression patterns underlie development, but their systematic detection in whole embryos has remained elusive. We introduce a whole-embryo imaging platform using multiplexed error-robust fluores...
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Portugues Lab @portugueslab.bsky.social · 07/01/2026
1/6: New publication from the lab: “Plastic landmark anchoring in zebrafish compass neurons” by Ryosuke Tanaka (@ryosuketanaka.bsky.social) and Ruben is available here: rdcu.be/eX1L4
rdcu.be
Plastic landmark anchoring in zebrafish compass neurons
Nature - Using two-photon microscopy with a panoramic virtual reality setup, how head direction cells in larval zebrafish integrate visual landmarks and optic flow to track orientation is revealed.
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Inbal Shainer @ishainer.bsky.social · 18/12/2025
Very proud to see our paper selected as one of Nature’s 2025 highlights! @johanneskappel.bsky.social @jlarsch.bsky.social @mpiforbi.bsky.social www.nature.com/articles/d41...
nature.com
Asteroids, antibiotics and ants: a year of remarkable science
Highlights from News & Views published in 2025.
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Nature @nature.com · 11/12/2025
“Up ’till now, we couldn’t detect it, because we didn’t look at the garbage cans of cells.” Yifat Merbl found a new trick of the immune system, and is part of Nature’s 10, a list of people who shaped science in 2025 go.nature.com/3XQWoUt
go.nature.com
This scientist found a new trick of the immune system by digging through cellular rubbish
Yifat Merbl is part of Nature’s 10, a list of people who shaped science in 2025.
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Portugues Lab @portugueslab.bsky.social · 24/11/2025
(1/n) We are excited to share our new paper in Nature Communications, by Hagar Lavian (@hlavian.bsky.social) and team, revealing how the zebrafish brain integrates visual navigation signals! www.nature.com/articles/s41...
nature.com
Visual motion and landmark position align with heading direction in the zebrafish interpeduncular nucleus - Nature Communications
How are various visual signals integrated in the vertebrate brain for navigation? Here authors show that different spatial signals are topographically organized and align to one another in the zebrafi...
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Hagar Lavian @hlavian.bsky.social · 04/12/2025
Very excited to share this thread on our recent paper! We show how Zebrafish integrate visual navigation signals in aligned topographic maps. Full thread below🧵
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Shawn Burgess @burgesslab.bsky.social · 17/11/2025
Folks, it is finally out! Our paper on T2T assemblies of the zebrafish genome is on BioRxiv: www.biorxiv.org/content/10.1...
biorxiv.org
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Stefan Luschnig @luschnig.bsky.social · 12/11/2025
Job Alert! The Institute for Neuro- and Behavioural Biology at the Faculty of Biology @uni-muenster.de invites applications for a Full Professorship (W3) in “Systems Neuroscience” - Highly attractive research environment at the Multiscale Imaging Center. Apply by January 5th. See shorturl.at/VczFp
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Oded Rechavi @odedrechavi.bsky.social · 06/11/2025
IT'S HAPPENING! 💥 I'm psyched to launch the collaboration between @qedscience.bsky.social & @openrxiv.bsky.social @biorxivpreprint.bsky.social! Preprint + q.e.d = your science is out there, and anyone can appreciate it. Let's care about making discoveries, and not on “getting published” (1/3) 👇
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David Schoppik @schoppik.com · 02/11/2025
Thread coming soon, but be the first to read the latest from @franziau.bsky.social!
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napari @napari.org · 21/10/2025
You might have noticed lots of activity in the napari project recently! 🚀 We're grateful for a grant from CZI that's keeping us going, but grants don't last forever: we're trying to figure out sustainable long term funding. Read our blog post to find out how you can help: napari.org/island-dispa...
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Sophie Caron @thecaronlab.bsky.social · 30/10/2025
1/ Hello Drosophila-philists and braino-maniacs! 👋🪰🧠🧪 The Caron lab has a new preprint, and it is about 🥁🥁🥁 democracy! Neuro-democracy, to be precise. So: drop EVERYTHING and listen up — a 🧶! www.biorxiv.org/content/10.1...
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Harvard_MCB @harvardmcb.bsky.social · 29/10/2025
Catherine Dulac Named Xander University Professor 🧠 🧪🧬 #AcademicSky #higherEd www.mcb.harvard.edu/department/n... @dulaclab.bsky.social @rachellegaudet.bsky.social @neurovenki.bsky.social @naoshigeuchida.bsky.social @harvardbrainsci.bsky.social @hhmi.org @cryptogenomicon.bsky.social
mcb.harvard.edu
Catherine Dulac Named Xander University Professor - Harvard University - Department of Molecular & Cellular Biology
MCB’s Catherine Dulac, Howard Hughes Medical Institute Investigator and renowned neuroscientist, has been appointed the Xander University Professor. Four Harvard scholars were recognized with appointm...
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Simon Fisher @profsimonfisher.bsky.social · 29/10/2025
More than two decades have passed since we discovered that rare disruptions of the FOXP2 gene disturb development of proficient speech/language skills. Today we know of multiple FOXP genes that are directly implicated in distinct brain-related conditions with differences in symptoms & severity.🧪 1/n
A depiction of expression patterns of the FOXP1, FOXP2, and FOXP4 genes in the brain, based on the developmental human RNA sequencing dataset of BrainSpan (http://www.brainspan.org/). Data cover different prenatal timepoints starting at 8-to-10 weeks postconception (abbreviated as pcs), postnatal timepoints from 0-to-12 months (abbreviated as mos), and expression measured in adulthood. A dashed vertical line represents time of birth. Individual dots are shown each representing one brain sample, and lines show loess curves fitted through the datapoints. The analyzed brain regions are A1C, primary auditory cortex; CB, cerebellum; CBC, cerebellar cortex; DFC, dorsolateral prefrontal cortex; DTH, dorsal thalamic nucleus; HIP, hippocampus; IPC, inferior parietal cortex; ITC, inferior temporal cortex; M1C, primary motor cortex; MD, mediodorsal thalamic nucleus; MFC, medial frontal cortex; OFC, orbitofrontal; S1C, primary sensory cortex; STR, striatum; TC, superior temporal cortex; V1C, primary visual cortex; VFC, ventromedial prefrontal cortex. This image comes from Figure 1 of a paper entitled “Molecular networks of the FOXP2 transcription factor in the brain” written by den Hoed, Devaraju and Fisher, published in the journal EMBO Reports in August 2021 (Volume 22, article e58203).
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Pawel Burkhardt @pawelburkhardt.bsky.social · 27/10/2025
First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience Our latest in @natrevneuro.nature.com Link: rdcu.be/eMX3E @jeffcolgren.bsky.social @msarscentre.bsky.social
rdcu.be
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution
Nature Reviews Neuroscience - Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were...
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Martin Haesemeyer @haesemeyerlab.bsky.social · 24/10/2025
Out now in @currentbiology.bsky.social led by Kaarthik A Balakrishnan: We identify medullary circuits that represent the valence of thermal stimuli and control both long-term strategies of cold-avoidance and short term hot avoidance behaviors to enable thermoregulation. www.cell.com/current-biol...
cell.com
Behavioral and circuit principles of temperature gradient navigation
Behavioral thermoregulation is critical for survival across animals. Balakrishnan and Haesemeyer discover that thermoregulatory behavior in larval zebrafish is organized into longer-term swim modes. T...
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Mike Fainzilber @mfainzilber.bsky.social · 11/10/2025
www.science.org/content/arti...
science.org
Perfume scientists tweak cells into having ‘sense of smell’
A study could transform the lab study of olfaction—and may challenge a Nobel-winning hypothesis
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Ben de Bivort @debivort.bsky.social · 08/10/2025
Our new study modeling selection for (behavioral) variability has been covered in a lovely @genetics-gsa.bsky.social podcast featuring first author Shraddha Lall and @ecoevogal.bsky.social academic.oup.com/g3journal/ad...
academic.oup.com
Family-based selection: an efficient method for increasing phenotypic variability
This article introduces a model comparing various selection regimes for increasing phenotypic variability. Individuals with the same genotype, reared in id
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Richard Benton @bentonlab.bsky.social · 06/10/2025
Having personally sworn for years that insects don’t use GPCRs for odour detection, Suguru Takagi (@sugurutakagi.bsky.social) discovers that, in fact, they sometimes do … www.biorxiv.org/content/10.1...
biorxiv.org
A GPCR signaling pathway in insect odor detection
Odor detection differs fundamentally in vertebrates, which use G protein-coupled receptors (GPCRs), and insects, which employ ion channels. Here, we report the first evidence for a GPCR defining tunin...
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Venki Murthy @neurovenki.bsky.social · 01/09/2025
Thrilled to share this work, long time in the making! Carried through creatively by @siddjakes.bsky.social after initial design & piloting by @trackingskills.bsky.social, with help from @trackingactions.bsky.social. Modeling in collaboration with Massimo Vergassola & Nicola Rigolli.
biorxiv.org
Mice navigate scent trails using predictive policies
Animals actively sense their environment to extract features of interest to guide behaviors. For mammals, odors are prominent environmental features which are sampled by active modulation of sniffing ...
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Janelia Research Campus @hhmijanelia.bsky.social · 26/08/2025
📢We're #hiring Group Leaders! Apply to lead a lab at Janelia & advance biology using theory, computational modeling & machine learning. 🔹5-year renewable appointment 🔹Pioneer new tools & approaches 🔹Collaborate across disciplines Apply by Nov. 4👉 janelia.link/groupleader
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