Remote activation of a single-AAV-deliverable photoswitchable Cas12f system enables precise spatial and temporal control of genome editing in deep tissues without surgery or implanted devices.

Across animal phyla, odor information is represented in the first olfactory processing center by combinatorial activation of discrete glomeruli. To examine how this organization of olfactory processin...

Transposable elements mobilize within and occasionally between genomes, including from host to virus. We identified two insertions of the human BC200 noncoding RNA gene in the poxvirus molluscum conta...

Scoliosis is a three-dimensional deformity of the vertebral column that commonly emerges during growth, yet the biological mechanisms that initiate and drive curve progression remain poorly understood...

This study shows that the brain arises from two distinct progenitors: one forms the forebrain and midbrain, whereas the other generates the hindbrain. These insights enable the generation of human hin...

The genomic regions regulating gene expression are often themselves transcribed into a variety of noncoding RNAs (ncRNAs). However, the regulatory roles of this noncoding transcription remain largely ...

Joan Birman thought her major discoveries were behind her. Then came an email from a young neighbor — a girl who knew little but wanted to learn.

Genetics profoundly influences aggression by shaping neural circuits, but the underlying mechanisms remain unclear. Here, authors show that strain differences in male mouse aggression are linked to di...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Spermatogonial stem cells (SSCs) maintain male fertility, but how their clonal dynamics change with age remains poorly understood. Here, we use in vivo CRISPR barcoding in zebrafish to label SSCs and ...

Abstract. Neurodiversity has received considerable attention recently from the general population and academic researchers, coinciding with an increase in

Thalamocortical projections shape the functional regionalization and parallel sensory computations across the mammalian cortex. However, the principles of thalamocortical computations in non-mammalian...

Convolutional Neural Networks (CNNs) trained for image recognition have demonstrated remarkable conceptual similarities to the primate ventral visual pathway, but their standard feedforward architectu...

THE CITY is now The City Reporter.Our name is new, but our work isn’t changing. The City Reporter is a reader-supported newsroom that covers New York's uncovered neighborhoods, holds the powerful...

By Dr. Rachel Simmons, Postdoctoral Fellow, Stanford University

YouTube video by Jimmy Awards

A Claude Skill to create an evidence review to inform specific health questions - DrCatHicks/informed-patient