Alex Schier @schierlab.bsky.social · 08/09/2026The first Danionella paper from the lab. Danionella cerebrum is transparent, so you can see all of the internal organs. But what sensory information are the organs sending to the brain? In our new preprint, Emily Bayer wanted to find out. 1/4 www.biorxiv.org/content/10.6... 18134
Reposted by Alex SchierBiozentrum, University of Basel @biozentrum.unibas.ch · 03/09/2026Congratulations to Yuping Li on being awarded a prestigious ERC Starting Grant. In her project, she will investigate how bacteria detect and defend themselves against giant viruses known as jumbophages.🧪 @yuping-li.bsky.social @unibas.ch @erc.europa.eu #ERCStartingGrant #research #lifesciencesbiozentrum.unibas.chERC Starting Grant for Yuping LiGiant viruses are masters in evading bacterial defense systems. With a Starting Grant from the European Research Council (ERC), Prof. Yuping Li will investigate how bacteria detect and fight these gia... 0414
Alex Schier @schierlab.bsky.social · 19/08/2026What regulates the urge to sleep? William Joo and colleagues identified brain regions that reflect how long mice have been awake. Strikingly, inhibiting one of these regions reduces sleep by 70%, without the major behavioral deficits associated with sleep deprivation. www.nature.com/articles/s41...nature.comWake-activated neuronal populations that regulate sleep drive - NatureWhole-brain activity mapping, targeted cell manipulations and electrophysiology in mice identify wake-activated neuronal populations that are crucial for sleep drive and can persistently red... 48631
Reposted by Alex SchierHHMI @hhmi-science.bsky.social · 20/07/2026"We have no business applying to this," #GilliamFellow Sara Makanani told her PI. Her mentor’s reply? "We are worthy of this." // 2nd- or 3rd-year PhD student? Talk to your faculty advisor — apps open 9/1 for our BIGGEST cohort of mentee-mentor pairs yet! bit.ly/gilliam26 0126
Alex Schier @schierlab.bsky.social · 06/07/2026Come join us at the @biozentrum.unibas.ch as Professor in Climate Biophysics. Blue-sky research, inspiring colleagues, and generous support. 1157
Alex Schier @schierlab.bsky.social · 17/06/2026Might cerebellar disinhibition underlie Restless Legs Syndrome symptoms? Will Joo found that loss of the RLS-associated gene meis1b perturbs locomotion in zebrafish by disinhibiting cerebellar output. www.sciencedirect.com/science/arti... 23410
Reposted by Alex SchierOded Mayseless @mayseless.bsky.social · 16/06/202611/11 Big picture: the larval zebrafish olfactory bulb is organized spatially, transcriptionally, and functionally in ways that reflect behavioral preference. Paper: www.biorxiv.org/content/10.6... 131
Reposted by Alex SchierOded Mayseless @mayseless.bsky.social · 16/06/20267/11 Luckily, @yinanwan.bsky.social and Jakob developed a powerful approach for multiplexed whole-mount gene-expression mapping. Sequentially imaging 68 genes in intact larval brains, defined anatomical and transcriptional boundaries of the olfactory bulb at cellular resolution. 121
Reposted by Alex SchierOded Mayseless @mayseless.bsky.social · 16/06/20261/11 Excited to share my postdoc work from @schierlab.bsky.social and Rainer Friedrich! 🐟👃 How does the brain decide whether an odor is good or bad? In larval zebrafish, we find that odor preference is reflected in spatially cohesive neuronal domains of the olfactory bulb. 🧵 26625
Reposted by Alex SchierbioRxiv Developmental Biology @biorxiv-devbio.bsky.social · 18/05/2026Interpretable decoding of cell fate from a snapshot of combinatorial signaling www.biorxiv.org/content/10.64898/20… 053
Reposted by Alex SchierBiozentrum, University of Basel @biozentrum.unibas.ch · 12/05/2026🧪 A new study led by Dr. Janani Durairaj and Prof. Torsten Schwede shows that current AI models in drug discovery still face limitations. Learn more👇 @ninjani.bsky.social @torstenschwede.bsky.social @unibas.ch @snsf.ch @natureportfolio.nature.com www.biozentrum.unibas.ch/news/detail/...biozentrum.unibas.chAI models still reach limits in drug discoveryDeveloping new medicines is a slow and costly process. For some years now, artificial intelligence (AI) has been considered a promising tool to accelerate drug discovery by identifying drug candidates... 0166
Reposted by Alex SchierScott Horton @robertscotthorton.bsky.social · 10/04/2026Jack Szostak "All of these things frighten me, and they should frighten you as well. I made the decision to create a life for myself here, because I viewed this as a place that rewarded determination, hard work, and integrity. It still has a chance to be that place again."open.substack.comI’m a Nobel Prize-winning immigrant. I can no longer recognize this country.Attacks on science and immigrants are destroying America. 5401136
Reposted by Alex SchierYinan Wan @yinanwan.bsky.social · 02/04/2026With this “Behind the paper” story, I’d like to give special thanks to two remarkable contributors whose generosity made a big difference: @jialinliu.bsky.social for the scMultiomics data behind the multiomic atlas, and Guoqiang Yu’s group for sharing ITEC cell tracking, which enabled MERFISH-FATE. 1349
Reposted by Alex Schierthe Node @the-node.bsky.social · 02/04/2026From fate to form: the journey to whole-embryo spatial transcriptomics In this 'Behind the paper' feature, @yinanwan.bsky.social shares the inside story of an ambitious journey with @schierlab.bsky.social & co. thenode.biologists.com/from-fate-to...thenode.biologists.comFrom fate to form: the journey to whole-embryo spatial transcriptomics - the NodeWhere molecules meet form I have long been interested in understanding how development emerges at the intersection of molecular and spatial organization. 1186
Reposted by Alex SchierSally Lowell @cellysally.bsky.social · 01/04/2026"We want to see the academic publishing industry change in a way that benefits science, not just profits" 02512
Reposted by Alex SchierJames Briscoe @jamesbriscoe.bsky.social · 01/04/2026A question I get asked all the time by @dev-journal.bsky.social authors "Why does it cost so much to publish a paper?" We break down the finances and explain where the money goes Spoiler: quality publishing takes a village (people + infrastructure) journals.biologists.com/dev/article/...journals.biologists.com‘Why is publishing so expensive?’For many of us who work in scientific publishing, the title of this Editorial is a question we hear all the time when we're out talking to academics. And it's a perfectly reasonable one. After all, re... 23916
Reposted by Alex SchierBiozentrum, University of Basel @biozentrum.unibas.ch · 23/03/2026Prof. Markus Rüegg and Dr. Judith Reinhard joined the Telebasel studio to talk about progress and the ongoing challenges of the gene therapy they’ve developed to treat LAMA2-related muscular dystrophy, a currently incurable and fatal muscle disease affecting children. telebasel.ch/sendungen/pu...telebasel.chBasler Forschende entwickeln Gentherapie gegen… | TelebaselUngefähr jedes Jahr wird in der Schweiz ein Kind mit einer schweren Muskelschwäche geboren. LAMA2-Muskeldystrophie ist unheilbar. Nun haben Forschende am… 031
Reposted by Alex SchierMadScientist @mads100tist.bsky.social · 16/03/2026It's out! Happy to present ITEC, a semi supervised algorithm with an extremely low error rate that can track cells in files of any size (think Terabytes!). We used it in many organisms, including zebrafish, to study how organs form and linked it to gene expression www.biorxiv.org/content/10.6... +🧪biorxiv.org 2019960
Reposted by Alex SchierBiozentrum, University of Basel @biozentrum.unibas.ch · 13/03/2026Embryogenesis in 4D: a developmental atlas for genes and cells 🧪 @schierlab.bsky.social developed a new method (#weMERFISH) that visualizes the activity of hundreds of genes across the entire zebrafish embryo with subcellular resolution. lnkd.in/eHY5gXDx @erc.europa.eu @snsf.ch @unibas.ch 0277
Reposted by Alex SchierUniversity of Basel @unibas.ch · 13/03/2026How does a tiny cluster of cells become an embryo? Researchers @biozentrum.unibas.ch mapped gene activity across the entire zebrafish embryo, creating a 4D atlas that links gene expression to cell movement & development. www.unibas.ch/en/News-Even...unibas.chEmbryogenesis in 4D: a developmental atlas for genes and cellsResearchers at the University of Basel create a 4D atlas revealing how thousands of genes shape embryonic development in the zebrafish embryo. 192
Reposted by Alex SchierYinan Wan @yinanwan.bsky.social · 12/03/2026Very grateful to everyone who made this work possible. I feel incredibly lucky to have worked with such an amazing team. Special thanks to: Jakob El Kholtei, KJ Jenie, @mcolomerr.bsky.social, and of course our wonderful collaborator Bogdan Bintu and my mentor @schierlab.bsky.social 3468
Alex Schier @schierlab.bsky.social · 12/03/2026Very happy to see this out. 👏 @yinanwan.bsky.social Bogdan Bintu and team. Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...science.orgWhole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesisGene expression patterns underlie development, but their systematic detection in whole embryos has remained elusive. We introduce a whole-embryo imaging platform using multiplexed error-robust fluores... 618780
Reposted by Alex SchierStand Up for Science! @standupforscience.net · 07/03/2026TODAY IS THE DAY. NATIONWIDE rallies in your local city are kicking off today to SAVE SCIENCE, PROTECT HEALTH, and DEFEND DEMOCRACY. Visit standupforscience.net/march7 to find your local rally! GET OUT THERE SCIENCE ACTIVISTS!!! #March7 #standupforscience #science #rally #savesciencestandupforscience.netStand Up for Science: March 7th, 2026 — STAND UP FOR SCIENCE 16525
Reposted by Alex SchierBiozentrum, University of Basel @biozentrum.unibas.ch · 02/03/2026The Summer Call for our prestigious, fully funded #PhDFellowships is now open to talented early-career scientists worldwide. 🔬 Rotation-based program 🌍 International community 🗓 Apply by May 8, 2026 Apply now and join a leading life sciences institute! www.biozentrum.unibas.ch/phd/internat...biozentrum.unibas.chBiozentrum PhD FellowshipsShare your passion for life sciences. If you are talented and highly motivated, want to broaden your horizons and are interested in a wide range of research topics, apply for one of the sought after B... 0910
Reposted by Alex SchierPauli Group (posts by Andi Pauli) @pauligroup.bsky.social · 01/03/2026One more week to finalize your applications for the 2026 MBL zebrafish course at Woods Hole! Application deadline extended to March 9. Please repost and forward to anyone interested in learning 'everything zebrafish'! www.mbl.edu/education/ad...mbl.eduZebrafish Development and Genetics | Marine Biological LaboratoryOver the past 30 years, the zebrafish has emerged as a powerful model system for the study of vertebrate development and disease. This course will focus on the development and genetics of zebrafish an... 076
Alex Schier @schierlab.bsky.social · 24/02/2026Deadline March 1. Join the new Dietschy Facility for Tissue Science. www.biozentrum.unibas.ch/open-positio...biozentrum.unibas.chResearch Specialist in Microscopy and Spatial Transcriptomics (80-100%) 176
Alex Schier @schierlab.bsky.social · 24/02/2026Deadline March 1. Join the new Dietschy Facility for Tissue Science. www.biozentrum.unibas.ch/open-positio...biozentrum.unibas.chResearch Specialist in Computational Neuroscience and Data Analysis (80-100%) 054
Alex Schier @schierlab.bsky.social · 24/02/2026Deadline March 1. Join the new Dietschy Facility for Tissue Science. www.biozentrum.unibas.ch/open-positio...biozentrum.unibas.chResearch Specialist in Image Analysis (80-100%) 095
Reposted by Alex SchierPauli Group (posts by Andi Pauli) @pauligroup.bsky.social · 11/02/2026Switching fields or wanting to become an expert in #zebrafish research? The @mblscience.bsky.social 2026 Zebrafish Development & Genetics course offers a fantastic opportunity to learn from leaders in the field! Application deadline: March 2 Please spread the word! www.mbl.edu/education/ad... 02830
Reposted by Alex SchierPeter Fabian @fabianlab.bsky.social · 06/02/2026Thinking about EZM2026 in Vienna? 🐟 Travel grants are now open for students & ECRs. 7–11 July 2026 | Deadline: March 15 Hope to see many of you there! @ezsociety.bsky.social #zebrafish 01110
Reposted by Alex SchierLouis-Jeantet Foundation @louisjeantetfdn.bsky.social · 15/01/2026FIONA DOETSCH @doetschlab.bsky.social @biozentrum.unibas.ch @unibas.ch is awarded the 2026 Louis-Jeantet Prize for Medicine for discovering the identity of neural stem cells in the adult mammalian brain and for demonstrating that they enable mammals to adapt to specific physiological states. 0187
Reposted by Alex SchierDr Emma Hodcroft @firefoxx66.bsky.social · 11/12/2025Best Christmas Card of 2025 award goes out to the @biozentrum.unibas.ch for this incredible building-themed-advent-calendar! Opening a window each day has been fantastic! ❄️☃️😁 0384
Alex Schier @schierlab.bsky.social · 03/12/2025We will miss you Madalena and follow your exciting research at MPIDresden@mpi-cbg.de 0111
Reposted by Alex SchierMadalena M. Reimão Pinto @madalenamrp.bsky.social · 02/12/2025This past month marked the end of an era at the @schierlab.bsky.social @biozentrum.unibas.ch. It was a meaningful, intense, often challenging, but also incredibly rewarding chapter of my scientific journey. Thank you all in the Schier Lab for the unconditional support and the Schierleading! 4305
Reposted by Alex SchierBiozentrum, University of Basel @biozentrum.unibas.ch · 02/12/2025🧪An international study led by Prof. Roderick Lim has discovered that nuclear pore complexes—gateways in the nuclear membrane—are not rigid or gel-like as once thought. Instead, their interiors are constantly moving and rearranging. @unibas.ch @snsf.ch 👉 www.biozentrum.unibas.ch/news/detail/...biozentrum.unibas.chShapeshifting gates guard the cell nucleusAn international study led by the University of Basel has discovered that nuclear pore complexes – tiny gateways in the nuclear membrane – are not rigid or gel-like as once thought. Their interiors ar... 2115
Reposted by Alex SchierPauli Group (posts by Andi Pauli) @pauligroup.bsky.social · 21/11/2025... and we would love to see you ALL - working with ANY fish model - join us in Vienna for www.ezm2026.org, the biggest fish meeting in 2026! We plan to have a special session 'beyond zebrafish' and would love to include talks representing other fish systems across all sessions. Pls spread the word!ezm2026.orgEuropean Zebrafish Society - Meeting 2026Create a professional science website with Avada. Showcase research, highlight discoveries, and engage your audience with custom, informative designs. 2127
Reposted by Alex SchierBiozentrum, University of Basel @biozentrum.unibas.ch · 17/10/2025Apply for our Master of Science in Physics of Life – training in cutting-edge research at the interface of physics, mathematics, engineering and life sciences. Scholarships available. Application deadline: 30 November. More: www.biozentrum.unibas.ch/education/de... @biozentrum.unibas.ch @unibas.ch 0109
Reposted by Alex SchierCarolyn Bertozzi @carolynbertozzi.bskyverified.social · 10/10/2025👏 👏 👏 orgchart.mit.edu/letters/rega...orgchart.mit.eduRegarding the Compact | MIT Organization ChartThe U.S. Department of Education recently sent MIT and eight other institutions a proposed “Compact for Academic Excellence in Higher Education," along with a letter asking that MIT review the document. 35615
Reposted by Alex SchierBiozentrum, University of Basel @biozentrum.unibas.ch · 29/09/2025Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging www.biozentrum.unibas.ch/open-positio... #biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging 04852
Reposted by Alex SchierBiozentrum, University of Basel @biozentrum.unibas.ch · 16/09/2025We’re proud of our global research community at the Biozentrum @unibas.ch! Our scientists from 40+ countries bring their passion & diverse cultures to every discovery. 🔬Join us: www.youtube.com/watch?v=p_Cg...youtube.comWorking at the Biozentrum Basel | World-Class Science & Life in SwitzerlandYouTube video by BiozentrumBasel 0114
Reposted by Alex SchierKatie Kindt @kt-kindt.bsky.social · 06/08/2025The Zebrafish Neurobiology meeting will be held this fall- Nov 19-22 at Cold Spring Harbor Laboratory. Abstracts are due Sept 5th. #cshlzebrafish Please join us in person or attend virtually with access to posters and oral sessions via zoom. meetings.cshl.edu/meetings.asp...meetings.cshl.eduZebrafish NeurobiologyCold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics. 041
Reposted by Alex SchierUniversity of Basel @unibas.ch · 04/09/2025Seven researchers from the University of Basel receive ERC Starting Grants – an exceptional result for the University of Basel. Over the next five years, they will each receive between EUR 1.5 million and EUR 2.3 million in funding.unibas.chSeven researchers from the University of Basel receive ERC Starting GrantsIn the competition for highly sought-after research funding from the European Research Council, seven researchers from the University of Basel convinced the jury with their project ideas. Over the nex... 0151
Reposted by Alex SchierBiozentrum, University of Basel @biozentrum.unibas.ch · 01/09/2025Save-the-date Career Event @unibas.ch – October 22, 2025 Join us for an inspiring two-part event: Interview with Thomas Schinecker, CEO of Roche; Panel with leaders from Roche and McKinsey & Company; Apéro & Networking. More information: www.biozentrum.unibas.ch/events/confe... 072
Reposted by Alex SchierMaxwell Shafer @maxshafer.bsky.social · 28/08/2025Now published @natecoevo.nature.com with @annika-nichols.bsky.social, our latest on the evolution of 𝘴𝘭𝘦𝘦𝘱 across 𝟲𝟬 𝘀𝗽𝗲𝗰𝗶𝗲𝘀 of cichlid fishes! doi.org/10.1038/s415... with members of the @schierlab.bsky.social and Salzburger labs, as well as the burgeoning Shafer lab @uoftcellsysbiol.bsky.social 17840
Reposted by Alex SchierBen Engel @cellarchlab.com · 26/08/2025BIG NEWS!! We will be hiring a new professor with 25 years of endowed funding at the @biozentrum.unibas.ch @unibas.ch, focused on using biophysics and structural biology to explore climate-related fundamental science topics. Come start an innovative research cluster with us! 🧪🔬🧶🧬🌾🌍 111481
Reposted by Alex SchierBiozentrum, University of Basel @biozentrum.unibas.ch · 26/08/2025🧪 The University of Basel is setting up a new endowed professorship in #ClimateBiophysics at the @biozentrum.unibas.ch, funded by the Georg H. Endress Foundation. This new professorship strengthens climate research @unibas.ch. www.biozentrum.unibas.ch/news/detail/...biozentrum.unibas.chNew endowed professorship strengthens climate research at the University of BaselThe University of Basel is setting up a new endowed professorship at the Biozentrum to make fundamental discoveries at the interface between biophysics and climate-relevant environmental biology. This... 15839
Reposted by Alex SchierBiozentrum, University of Basel @biozentrum.unibas.ch · 25/08/2025Assistant Project Coordinator – Biozentrum PhD Fellowships – PhD Student Office (80% - 100%) www.biozentrum.unibas.ch/open-positio... #Biozentrum #Basel #joboffer #hiring #job #recruiting #careers #Assistant #ProjectCoordinator 002
Reposted by Alex SchierBiozentrum, University of Basel @biozentrum.unibas.ch · 11/08/2025NCCR AntiResist, “New approaches to combat antibiotic-resistant bacteria”, is recruiting a Scientific Officer (80-100%) lnkd.in/eEU7CBTb @biozentrum @unibas.ch #Biozentrum #Basel #research #science #joboffer #hiring #job #recruiting #careers #Scientific #Officer #NCCR #AntiResist 155
Alex Schier @schierlab.bsky.social · 10/08/2025Everything (and more) you wanted to know about Nodal Signaling. A Paradigm for TGFβ Signaling in Embryonic Development | Annual Reviews - www.annualreviews.org/content/jour...annualreviews.orgNodal Signaling: A Paradigm for TGFβ Signaling in Embryonic Development | Annual ReviewsNodal signaling molecules are TGFβ family ligands that arose early during bilaterian evolution and are crucial for several key steps in embryonic development. They regulate the specification of mesode... 0155
Reposted by Alex SchierBiozentrum, University of Basel @biozentrum.unibas.ch · 04/08/2025Apply now for the prestigious and independent #BiozentrumPhDFellowships. Great science. Unique rotation-based selection of research group and other incentives. The summer call is open until October 12, 2025. bit.ly/4caiqqX @biozentrum.unibas.ch @unibas.ch #fellowship #PhD#Switzerlandbit.lyBiozentrum PhD FellowshipsShare your passion for life sciences. If you are talented and highly motivated, want to broaden your horizons and are interested in a wide range of research topics, apply for one of the sought after B... 01516