Flagella are large transenvelope nanomachines but how they transit the peptidoglycan in gram-positive bacteria is poorly understood. A recent model...

RNA modifications play an important role in biological processes. Mapping the diversity of RNA chemistry and studying the biological function of in...

Title: ASSISTANT PROFESSOR IN HOST-MICROBE INTERACTIONS (IMMUNOLOGY, MICROBIOLOGY)Employee Classification: Asst ProfessorDivision Name: Academic AffairsCollege/Unit: College of Arts and SciencesDepart...

Job Description The Department of Biological Sciences in the College of Science at Virginia Tech seeks applicants for two (2) tenure-track research and teaching positions at the Assistant/Associate ...

npj Biofilms and Microbiomes - MeeY and YybP, two proteins regulated by manganese-sensing riboswitches, are required for Bacillus subtilis biofilm formation

Mounting global responses to dynamic environmental conditions is a crucial function that bacterial cells must perform. Global regulatory networks are most often studied in individual species, however,...

Researchers are racing to culture a menagerie of exotic organisms and finding lots of surprises along the way.

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

The ribosomal rRNA methyltransferase GidB is involved in the discrimination of mischarged tRNAs in mycobacteria.

Sun, Wu et al. identify AvaS as a pyridoxal-phosphate-dependent RNA-modifying enzyme, producing the tRNA modification ava2C from k2C in bacteria and plants and linking RNA chemistry to translational r...

The Department of Biology at UNC Greensboro (UNCG) seeks an individual with a strong record of accomplishment in microbiology broadly defined for a tenure-track faculty position at the rank of Assista...

Many prokaryotes are diderms. They divide using an FtsZ division ring to simultaneously constrict physically coupled inner and outer membranes to form daughter cells with two membranes. Currently, onl...

Recent years have witnessed a rapid expansion in bacterial defense mechanisms. Alongside established defenses against molecular parasites, hundreds of novel mechanisms are being described annually, co...

Staphylococcus aureus α-toxin (AT) is a potent pore-forming toxin that causes cell damage during infection. The structure and activity of AT have been studied extensively, but the environmental factors...

Carbonic anhydrase (E.C. 4.2.1.1) is an enzyme that catalyzes the reversible hydration of CO2 to carbonic acid (H2CO3), which dissociates to bicarbonate (HCO3-) at intracellular pH. Copious amounts of...

Abstract. Eukaryote-associated microbes are ubiquitous, but their essential roles in the development and ecology of their host is yet to be fully understoo

A colibactin-producing symbiont in honeybee guts defends against opportunistic pathogens and confers protection.

Bacterial cell division has been extensively studied in model systems, but little is known about how this essential process occurs in the clinically important pathogen Clostridioides difficile. Studie...

Bacterial ecospecies are a recently recognized genetic structure that is hypothesized to arise by complex adaptation to a new niche. Coadaptation within the “Molassodon” ecospecies of Vibrio parahaemo...

Nucleotide-binding and oligomerization domain-like receptors (NLRs) are conserved molecular switches that regulate innate immunity across diverse domains of life. While best known for their roles in i...

Sequential peptidoglycan carboxylase activity of DacA and DacB generates a local peptidoglycan signature that recruits MapZ and establishes the division site at the Streptococcus pneumoniae cell equat...

The bacterial cell cycle is an ensemble of integrated pathways that coordinates cell growth and division. Although these pathways contain a suite of promising antimicrobial targets, their functional o...

UNIVERSITY OF MICHIGAN FACULTY POSITION IN CELL & MOLECULAR BIOLOGY AND RELATED FIELDS   The Department of Molecular, Cellular, and Developmental B...

npj Biofilms and Microbiomes - Drug repurposing for glucosyltransferase inhibition for targeted oral biofilm disruption

Staphylococcus aureus divides along sequential orthogonal planes, but the function of this geometry has remained unclear. Ramos-León et al. show that orthogonal division promotes uniform deployment of...

Multicellular cyanobacteria have evolved sophisticated cell–cell communication machinery to exchange, synchronize, and coordinate the efforts of individual cells. Analogous to gap junctions that have ...

In this Review, Papenfort discusses established and emerging aspects of bacterial small RNAs (sRNAs), their molecular mechanisms and regulatory principles, and the global impact of sRNAs on cellular gene expression profiles.