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vanipande.bsky.social

@vanipande.bsky.social

25 followers 36 following 1 posts

Postdoctoral fellow at NIH (USA). Bacterial cell biology, protein localization, microscopy. Views are my own.

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Reposted by @vanipande.bsky.social

Kumaran Ramamurthi @ramamurthilab.bsky.social · 15/09/2026

How do proteins localize in bacteria? Usually by binding to a prelocalized protein-but how does that protein localize? @vanipande.bsky.social found a #Bacillus subtilis protein that localizes via a lipid cue,undecaprenyl phosphate,that guides it to sites of PG synthesis www.pnas.org/doi/10.1073/...

pnas.org

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

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Reposted by @vanipande.bsky.social

Félix Ramos-León @felixrl.bsky.social · 18/08/2026

Excited to share my latest work in the @ramamurthilab.bsky.social, now in @cp-cellreports.bsky.social! We show that division geometry organizes surface adhesins in S. aureus and enables the formation of abscess communities that protect bacteria from immune cells. www.cell.com/cell-reports...

cell.com

Orthogonal cell division mediated by PcdA organizes surface virulence factors to drive staphylococcal abscess community formation

Staphylococcus aureus divides along sequential orthogonal planes, but the function of this geometry has remained unclear. Ramos-León et al. show that orthogonal division promotes uniform deployment of...

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Reposted by @vanipande.bsky.social

Félix Ramos-León @felixrl.bsky.social · 16/06/2026

Looking forward to it!!

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vanipande.bsky.social @vanipande.bsky.social · 29/05/2026

How do proteins know where to go? Some sense membrane curvature. Many follow other proteins. But what defines the first localization cue? In our bioRxiv preprint we tackle this question using a sporulation protein ShfA in Bacillus subtilis.

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Reposted by @vanipande.bsky.social

Kumaran Ramamurthi @ramamurthilab.bsky.social · 29/05/2026

Bacterial transmembrane proteins usually localize inside the cell by "finding" a pre-localized protein, but how did the 1st protein get there? @vanipande.bsky.social found a protein in #B.subtilis that localizes by recognizing a *lipid* localization cue. #Microsky www.biorxiv.org/content/10.6...

biorxiv.org

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