Dorsal and ventral noradrenergic neurons in the locus coeruleus form topographic subpopulations whose projection patterns and activity encode choice switching, reward-prediction errors and disregard o...

An imaging system developed to record cellular activity throughout the whole body of zebrafish captures cellular organ dynamics and identifies multiple distributed circuits.

Interactions between the prefrontal cortex (PFC) and hippocampus (HPC) are crucial for flexible and memory guided behaviour. Because there are no direct projections from PFC to HPC, it is widely presu...

Nature Mental Health - Embracing pharmacological complexity

Nature Neuroscience - Charbonneau et al. compare how the insula is structured and functions in humans, monkeys and rodents, revealing similarities and differences across species that are likely to...

To make flexible decisions, the brain needs to make inferences between events that were not directly experienced together. In sharp-wave ripple (SWR) events, during periods of rest and sleep, spiking ...

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Functional heterogeneity of dorsal raphe nucleus is not fully understood. Here authors show topographically organized sensory and locomotor responses from the zebrafish dorsal raphe and its forebrain ...

Cortical circuits prioritize diversity over categorical structure, supporting a computational regime geared towards high-dimensional, highly separable neural representations.

Higher-order thalamic nuclei are critical in cognition and generate spike sequences termed bursts. The role of bursts in cognition is unknown. We found that pulvinar bursts are attention-modulated, predict behavior, and influence the cortex. Pulvinar electrical microstimulation triggered bursts that enhanced target detection, revealing mechanistic thalamic control over the cortex and behavior.

Kurzgesagt is a Youtube channel that breaks down science topics for a broad audience. They have great videos, both in terms of narrative, animation, and scientific accuracy. A few days ago, the cha…

Molecular Psychiatry - A new hope: locus coeruleus-norepinephrine system at the nexus of neuropsychiatric symptoms

Uniting the Australian human brain mapping community.

Free interactive tool: enter bregma-relative AP/ML/DV coordinates to navigate Allen Mouse Brain Atlas coronal and sagittal sections. Brain regions identified in real time.

Dendrites are the tree-like arborizations of neurons through which they receive input from other neurons. This compartmentalized anatomy has given rise to the idea that individual dendrites process…

Flexible learning relies on integrating sensory and contextual information to adjust behavioral output in different environments. The anterolateral motor cortex (ALM) is a frontal area critical for ac...

Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.

The Research Associate (Level A) is expected to contribute towards the research effort of UNSW and to develop their research expertise through the pursuit of defined projects relevant to their particu...

Serotonergic psychedelics are known for their profound effects on consciousness and are gaining renewed interest as potential psychiatric treatments. …

Volume EM and connectome reconstruction of the apical organ of a ctenophore combined with high-speed imaging reveals a neuronal coordination of balancer cilia in the gravisensory organ.

Baracchini et al. reveal that temporal variability in fMRI brain signals encodes biologically meaningful information across spatial and temporal scales, highlighting its role in healthy brain function...

Noradrenergic circuits support and balance aggressive behavioural states in predatory nematodes, distinguish predatory from non-predatory nematode species and are associated with the evolution of comp...