Sign in

Lorenzo Posani

@lorenzoposani.com
750 followers 712 following 71 posts

Coding and de-coding brains👨‍💻 ⮂ 🧠 Posani Lab at ICM Paris Brain Institute & CNRS Co-founder of Cubbit

PostsRepliesMedia
Lorenzo Posani @lorenzoposani.com · 19h
If you are at Bernstein, come by at poster 60 session IV (Wed 2pm), Charlotte will present our results on compositional and abstract representations of social stimuli in the monkey face patch system. Particularly proud of this as it’s the first poster from the first student of the lab 😊
0106
Reposted by Lorenzo Posani
Alejandra Caraballo @esqueer.net · 27/09/2026
Google finally updated some of its satellite images of Gaza and my god, it's horrific. The entirety of Rafah has been demolished. The majority of Khan Younis is in ruins. Entire towns completely leveled and erased of the map.
9251843165
Reposted by Lorenzo Posani
Randall Munroe @xkcd.com · 17/09/2026
Summer xkcd.com/3299/
4-panel comic. (1) [Person swings from tree over water.] (2) [In the middle of the swing, the tree’s leaves have turned brown.] (3) [When the person lets go, the tree is bare of leaves and everywhere is covered in ice or snow.] (4) [The person landed on the ice looks behind at Person 2 with shoulder-length hair standing on the snow.] PERSON 2: Summer over already, huh? PERSON 1: It seemed extra quick this year.
472953369
Reposted by Lorenzo Posani
Dr. Liz Kirby @thekirbylab.bsky.social · 13/09/2026
🎯
By prompting students to turn to AI instead of to their fellow students, TAs, or professors, these technologies offer the illusion that human interaction is inconsequential. But learning with and from other people simultaneously supports learning and builds the human skills that make the world go ’round.
3490133
Reposted by Lorenzo Posani
Marisa Kabas @marisakabas.bsky.social · 07/09/2026
pay living wages for all workers. tax the shit out of billionaires. happy labor day.
3645851157
Reposted by Lorenzo Posani
Nicole Rust @nicolecrust.bsky.social · 04/09/2026
The superposition of these two studies — both incredible — reflect a snapshot of "one big thing" systems neuroscience has yet to resolve. In mice: 1. Task-related signals are everywhere. 2. Absent large swaths of "everywhere," suprisingly sophisticated learning & behavior remains.
Post by Enny van Beest, "Brainwide representation of navigation"Post by Jieyu Zheng, "How fast can mice learn complex mazes?"
1011838
Reposted by Lorenzo Posani
Enny van Beest @ennyvb.bsky.social · 04/09/2026
Textbook: tracking position during navigation is primarily the job of the hippocampus. Recent findings suggest a more complicated story. Recording >20k neurons brainwide, we indeed find spatial representations in every region! With @kenneth-harris.bsky.social and @carandinilab.net
Brainwide representations of a virtual corridor
416551
Reposted by Lorenzo Posani
Eric Schares @eschares.bsky.social · 31/08/2026
🚨Update: Our analysis of global APC expenditure has now been expanded to cover more publishers (7 -> 14) and more years (2019-2025). We estimate $15B in APCs paid over seven years, $3.7B in 2025 alone. Elsevier crosses the $1B threshold by itself in 2025. arxiv.org/abs/2608.16322 #ScholComm
Line chart showing 5 biggest publishers from 2019-2025
6179147
Reposted by Lorenzo Posani
Alireza Modirshanechi @modirshanechi.bsky.social · 15/08/2026
Excited to share that I'll be starting as a junior professor and Emmy Noether awardee at the University of Göttingen this October! 🥳 🚀 I'll be hiring #phd students and #postdoc across #machinelearning, #neuroscience and #cogsci: modirlab.github.io/open-positio... Please spread the word! 🙏
PhD ad informationPostdoc ad informationInformation about Göttingen and equal opportunities
1217059
Reposted by Lorenzo Posani
Jack Mirkinson @jackmirkinson.bsky.social · 11/08/2026
Today in @thenation.com: a harrowing piece written from inside the Dilley ICE detention center by Maryam Tahmasebi, a green card holder who's been locked up along with her husband and son for months despite none of them committing any crime. www.thenation.com/article/soci...
thenation.com
One Woman’s Message From the Hell of ICE Detention
My husband, son, and I have been locked up for months—despite being permanent residents with no criminal record. It is an unendurable, unending nightmare.
11835232212
Reposted by Lorenzo Posani
Laura Driscoll @lndriscoll.bsky.social · 08/08/2026
Confused about all this talk of compositionality in neuroscience? Read our new perspective www.nature.com/articles/s41... with authors Reidar Riveland and Alex Pouget.
nature.com
The compositionality continuum as a principle for studying the neural basis of intelligence - Nature Neuroscience
Compositionality exists on a continuum of increasing complexity rather than as a binary trait. Studying its implementation in simpler biological and artificial systems is the most tractable path towar...
212143
Reposted by Lorenzo Posani
Lorenzo Posani @lorenzoposani.com · 06/08/2026
Fin/ check out the paper at www.nature.com/articles/s41...! Huge thanks to Pia O'Neill (new assistant prof at Dartmouth sites.dartmouth.edu/oneill-lab/) for leading this project, and to @stefanofusi.bsky.social & Daniel Salzman for the fantastic collaboration! Cover artwork matteofarinella.com/
nature.com
The representational geometry of emotional states in basolateral amygdala - Nature Neuroscience
O’Neill, Posani and colleagues show that while single amygdala neurons encode multiple emotional state-related variables (for example, valence, fear and safety), population-level geometry can enable o...
0177
Lorenzo Posani @lorenzoposani.com · 06/08/2026
For a neural circuit to be "specialized", does it need specialized neurons? In our new work - now out in @NatureNeuro - we address this question in the BLA, using representational geometry to propose a new population-centric way of defining circuit specialization. 🧵👇 1/
39228
Reposted by Lorenzo Posani
Abid Hussaini @hussainilab.bsky.social · 31/07/2026
Very proud to announce our recently published paper led by Gustavo Rodriguez et al. Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of aged APP knock-in mice: www.cell.com/cell-reports...
cell.com
Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of aged APP knock-in mice
Using the Earth Mover’s Distance and machine learning techniques, Rodriguez et al. show increased instability in spatial representations and impaired spatial information coding in the medial entorhina...
151
Reposted by Lorenzo Posani
Earl K. Miller @earlkmiller.bsky.social · 28/07/2026
Most neurons seem to be generalists, not specialists. Cortical circuits prioritize diversity over categorical structure. Rarely categorical, highly separable representations along the cortical hierarchy www.nature.com/articles/s41... #neuroscience www.newscientist.com/article/2581...
nature.com
Rarely categorical, highly separable representations along the cortical hierarchy - Nature
Cortical circuits prioritize diversity over categorical structure, supporting a computational regime geared towards high-dimensional, highly separable neural representations.
0407
Reposted by Lorenzo Posani
neurosock @neurosock.bsky.social · 16/07/2026
This recent post by @earlkmiller.bsky.social got my attention. It shows how abstraction could emerge in the primate PFC. The paper is hard, but the main idea can be simplified to low-dims, so I made fun a little animation. A🧵with my toy model and notes: #neuroskyence #compneuro #NeuroAI
14316
Reposted by Lorenzo Posani
Columbia University's Zuckerman Institute @zuckermanbrain.bsky.social · 15/07/2026
Scientists have long debated whether neurons are jacks of all trades or tend to specialize in one thing. Now @stefanofusi.bsky.social, @lorenzoposani.com & Liam Paninski present new evidence in @nature.com shedding light on how the brain performs complex tasks. tinyurl.com/yj3ew8en
04213
Reposted by Lorenzo Posani
stefanofusi.bsky.social @stefanofusi.bsky.social · 15/07/2026
From a great collaboration with @lorenzoposani.com, @shuqiw.bsky.social, Samuel Muscinelli, Liam Paninski, now in Nature: www.nature.com/articles/s41...
nature.com
Rarely categorical, highly separable representations along the cortical hierarchy - Nature
Cortical circuits prioritize diversity over categorical structure, supporting a computational regime geared towards high-dimensional, highly separable neural representations.
011334
Lorenzo Posani @lorenzoposani.com · 15/07/2026
Out today on @nature.com! Connecting neural specialization, population geometry, and their functional implications across the cortical hierarchy. So grateful for this beautiful and fun collaboration with @shuqiw.bsky.social, S Muscinelli, L Paninski, and @stefanofusi.bsky.social!
nature.com
Rarely categorical, highly separable representations along the cortical hierarchy - Nature
Cortical circuits prioritize diversity over categorical structure, supporting a computational regime geared towards high-dimensional, highly separable neural representations.
213545
Reposted by Lorenzo Posani
Shuqi Wang @shuqiw.bsky.social · 15/07/2026
Our paper "Rarely categorical, highly separable representations along the cortical hierarchy" is now out in Nature! www.nature.com/articles/s41... In this paper, we studied whether the brain is well-organized and interpretable, both globally and locally. (See thread below.)
nature.com
1228
Reposted by Lorenzo Posani
Ben Hayden @benhayden.bsky.social · 24/06/2026
New lab paper ! "Shared neural geometries for bilingual semantic representations in human hippocampal neurons" led by @xinyuanyan.bsky.social. 🧵 www.sciencedirect.com/science/arti...
sciencedirect.com
Shared neural geometries for bilingual semantic representations in human hippocampal neurons
The human brain has the remarkable ability to comprehend and express similar concepts in multiple languages. To understand how it does so, we examined…
48328
Reposted by Lorenzo Posani
Abbey @abbeyarletto.bsky.social · 23/06/2026
When reality surpasses fiction! Top: fictional forecast for August 2050, broadcast by French TV in 2014 to warn about the consequences of global warming. Bottom: Real French forecast for yesterday, June 22, 2026.
236168357552
Reposted by Lorenzo Posani
Trish Greenhalgh @trishgreenhalgh.bsky.social · 23/05/2026
Every summer I repost this article on how to spot drowning. Please read it and pass on. In the last few years I’ve had SIX messages from people who saved a kid’s life after clicking on the link from my feed. slate.com/technology/2...
slate.com
Drowning Doesn’t Look Like Drowning
Drowning is not the violent, splashing call for help that most people expect.
253133989736
Reposted by Lorenzo Posani
jamelle @jamellebouie.net · 12/04/2026
more seriously congrats to the hungarian people for kicking that asshole out
142227612561
Reposted by Lorenzo Posani
Nature @nature.com · 30/03/2026
Becoming a parent is much more detrimental to women’s academic careers than it is to men’s Read the full story: go.nature.com/4v4rxmQ
IMPACT OF PARENTHOOD ON UNIVERSITY EMPLOYMENT. Line graph shows how the probability of holding a research position changes from four years before to seven years after having children.
6252155
Reposted by Lorenzo Posani
Katie Mack @astrokatie.com · 27/02/2026
In my utopian vision of the future, instead of offloading all the pointless, annoying work tasks (like reports that none one will read and needlessly opaque forms) to robots, we restructure work and society so that the pointless tasks don't happen at all.
62380374
Reposted by Lorenzo Posani
mcc @dryad.technology · 04/02/2026
Somebody should invent a socioeconomic system which is good at allocating resources
2995903683
Reposted by Lorenzo Posani
Joao Barbosa @jbarbosa.org · 27/01/2026
Postdoc position in Paris: come help develop new generation human brain computer interfaces ⚡🧠💻 Interested? Contact me if you have experience with machine learning (e.g. simulation-based inference, RL, generative/diffusion models) or dynamical systems. See below for + details and retweet 🙏
37456
Reposted by Lorenzo Posani
Sanjay Srivastava @sanjaysrivastava.com · 27/01/2026
Street art memorializing Alex Pretti in Seattle. Per r/Seattle, it was painted on a building facing Swedish Hospital in the First Hill neighborhood www.reddit.com/r/nursing/co...
A bearded man in nurse's scrubs offers aid to Justice, wearing a blindfold and holding a sword and scales, who has fallen to her knees.
10079742481
Reposted by Lorenzo Posani
G Elliott Morris @gelliottmorris.com · 24/01/2026
Reminder: All it would take to end the murder of American citizens by an untrained government goon squad is 16 Republicans in Congress voting with Dems to defund ICE (or 23 to impeach and remove Trump — 3 in House & 20 in Senate). That’s it. 23 Americans can vote for the public and end all of this.
222131175036
Reposted by Lorenzo Posani
sam @samthielman.com · 22/01/2026
I just thought everyone should see this
Dr Kareem Carr
man: i wish to publish
@kareem_carr
Jan 21
reviewer 2: your paper is no good
man: i'll do anything to improve
reviewer 2: it's simple. you must read the work of the great scientist Pagliarini
man: *bursts into tears* but i am Pagliarini
Andre Pagliarini
@apagliar
Jan 21
a first: in rejecting an article I submitted to a journal, reviewer 2 noted I failed to engage the work of one Andre Pagliarini
Jan 21, 2026 • 3:47 PM UTC
43252985990
Reposted by Lorenzo Posani
Kendra "Gloom is My Beat" Pierre-Louis @kendrawrites.com · 05/11/2025
I knew it would take less than a day for a tiktok dj to make something.
257196925794
Reposted by Lorenzo Posani
Kat Abughazaleh @katmabu.bsky.social · 05/11/2025
Good things are possible and we don’t have to settle.
246463598010
Reposted by Lorenzo Posani
Erica Ifill @wickdchiq.bsky.social · 05/11/2025
Everyone is hope scrolling now
895968886
Reposted by Lorenzo Posani
Zohran Kwame Mamdani @zohrankmamdani.bsky.social · 05/11/2025
31168598318089
Reposted by Lorenzo Posani
Matteo Carandini @carandinilab.net · 03/11/2025
Europe's MSCA postdoctoral fellowships are now attracting many researchers who would have gone to the US. So the payline has dropped below 10% (~1,600 fellowships to 17k applicants). Super tough situation. One more reason to double the next Horizon budget, as proposed by the EU Commission.
16226
Lorenzo Posani @lorenzoposani.com · 11/07/2025
Absolute peak graphical abstract in this Cell paper about reprogramming the leaf-cutter's brains 😂 www.sciencedirect.com/science/arti...
0136
Reposted by Lorenzo Posani
Pedro Vale @pfvale.bsky.social · 10/07/2025
"The myth of meritocracy in science collapses under the financial sacrifices expected at every career stage. From unpaid internships and self-funded conferences to underpaid positions, these hidden costs disproportionately exclude those without generational wealth, compounded by race and gender."
dx.plos.org
Too poor to science: How wealth determines who succeeds in STEM
From student to researcher, a career in science can come with a high price tag. This Perspective explores how persistent financial barriers limit who can succeed in science, revealing how wealth shape...
03518
Reposted by Lorenzo Posani
Pasquale Minervini @neuralnoise.com · 05/07/2025
"in 2025 we will have flying cars" 😂😂😂
839991
Reposted by Lorenzo Posani
lucyfree 🦋 @lucyfr.ee · 28/06/2025
yes to all three
129833
Reposted by Lorenzo Posani
Sofie Cairo @cairosofie.bsky.social · 22/05/2025
🚨 New WP! 📄 "Publish or Procreate: The Effect of Motherhood on Research Performance" (w/ @valentinatartari.bsky.social 👩‍🔬👨‍🔬 We investigate how parenthood affects scientific productivity and impact — and find that the impact is far from equal for mothers and fathers.
220599
Lorenzo Posani @lorenzoposani.com · 23/03/2025
I feel you captain
Revisitation of the Tintin and captain Haddock meme “what a week uh? Captain it’s Wednesday” meme where “week” becomes “year” and Tintin reminds the captain that we are still in march
070
Reposted by Lorenzo Posani
Laura Bassett @lebassett.bsky.social · 20/03/2025
Roses are red Violets are blue
24686099113413
Reposted by Lorenzo Posani
Camillo Padoa-Schioppa @camillopadoasch.bsky.social · 14/03/2025
New collaborative ms! We built & trained a neural network that is biophysically realistic, performs multiple economic choice tasks, and provides insights into orbitofrontal cortex. (We = Aldo Battista 😉) www.biorxiv.org/content/10.1...
biorxiv.org
A Neural Circuit Framework for Economic Choice: From Building Blocks of Valuation to Compositionality in Multitasking
Value-guided decisions are at the core of reinforcement learning and neuroeconomics, yet the basic computations they require remain poorly understood at the mechanistic level. For instance, how does t...
0157
Reposted by Lorenzo Posani
John Burn-Murdoch @jburnmurdoch.ft.com · 14/03/2025
NEW 🧵 Is human intelligence starting to decline? Recent results from major international tests show that the average person’s capacity to process information, use reasoning and solve novel problems has been falling since around the mid 2010s What should we make of this? www.ft.com/content/a801...
2892027813
Reposted by Lorenzo Posani
Sherrilyn Ifill @sifill.bsky.social · 28/02/2025
None of us can be sure what will “work.” You try multiple things and find your way in. Read some histories of the Civil Rights Movement by those who participated. They were never “sure” of what would work. Some campaigns fizzled out. But persistence, creativity, determination, and focus were key.
469250285983
Reposted by Lorenzo Posani
Fanny Cazettes @fannycazettes.bsky.social · 17/02/2025
Excited to announce multiple #PhD & #Postdoc positions opening in my lab over the next three years as part of the #ERC Starting grant DIVERSE! Reposts appreciated 😊 #neuroscience #neuroskyence
14140
Reposted by Lorenzo Posani
Earl K. Miller @earlkmiller.bsky.social · 13/02/2025
Cortical neurons are rarely specialized (except in primary cortical areas) but still carry high-dimensional info. Here's how and why Rarely categorical, always high-dimensional: how the neural code changes along the cortical hierarchy www.biorxiv.org/content/10.1... #neuroscience
biorxiv.org
Rarely categorical, always high-dimensional: how the neural code changes along the cortical hierarchy
A long-standing debate in neuroscience concerns whether individual neurons are organized into functionally distinct populations that encode information differently ("categorical" representations) and ...
0587
Reposted by Lorenzo Posani
stefanofusi.bsky.social @stefanofusi.bsky.social · 13/02/2025
We always see that 1) neural responses are very diverse 2) the shattering dimensionality is as high as it can be. Now also in an extensive analysis of the IBL dataset. Wonderful collaboration with @lorenzoposani.com, Shuqi Wang, Samuel Muscinelli, Liam Paninski. Many new analyses in this new version
0218