Rohner et al. develop Alpha1DLight, an α1D-adrenergic receptor-derived fluorescent indicator that enables subtype-resolved norepinephrine imaging. The sensor shows high affinity, reversible responses,...

Improved red and green indicators for norepinephrine and their characterization are reported. These indicators allow detection of norepinephrine release in awake behaving mice in dual-color fiber phot...

Within the nucleus accumbens shell, a spatially defined rostral subregion selectively modulates hedonic feeding, revealing functional heterogeneity in reward circuitry underlying food consumption.

Nature Neuroscience - Astrocytes modulate complex brain functions. These ubiquitous glial cells constitute a multilayered system of functional units that operate across multiple spatial scales,...

Nature - De novo design of miniproteins targeting GPCRs

Improved red and green indicators for norepinephrine and their characterization are reported. These indicators allow detection of norepinephrine release in awake behaving mice in dual-color fiber phot...

Improved red and green indicators for norepinephrine and their characterization are reported. These indicators allow detection of norepinephrine release in awake behaving mice in dual-color fiber phot...

A family of rationally designed time-resolved fluorescent proteins with controllable lifetimes across the visible spectrum enables simultaneous multiplexed live imaging, super-resolution microscopy, a...

Serotonergic enterochromaffin cells of the intestine exhibit distinct sensory, secretory and physiological properties depending on their location within the complex crypt–villus architecture of t...