General anesthetics seem to work in all living species. This raises the question of whether there are common changes in neural activity that occur during transitions between wakefulness and anesthesia...

Cortical pyramidal neurons project a long apical dendrite to layer 1 (L1), to receive synaptic inputs that are thought to provide contextual and possibly suppressive modulation. In visual cortex, thes...

Functional synapse clusters (FSCs) are synapses with correlated presynaptic activity that are colocalized on the same neuronal dendritic branch. FSCs have been observed after learning in cortical and ...

Modern artificial intelligence (AI) systems have achieved remarkable capabilities, but at an extraordinary energy cost. Training and running large-sca…

Neurons fire much more erratically than researchers thought. What does that mean for how the brain works?

The genetically encoded voltage indicators JEDI3sub and JEDI3hyp enhance monitoring of subthreshold neuronal activity in the awake mouse brain using a variety of two-photon microscopy techniques.

Flexible learning relies on integrating sensory and contextual information to adjust behavioral output in different environments. The anterolateral motor cortex (ALM) is a frontal area critical for ac...

The decision means that the US biomedical agency has to restore funding to hundreds of research projects, but the government will likely appeal.

Artificial neural networks are becoming more advanced and human-like in detail and behavior. The notion that machines mimicking human brain computations migh...

Synaptic plasticity underlies learning by modifying specific synaptic inputs to reshape neural activity and behavior. However, the rules governing which synapses will undergo different forms of plasti...

Biological intelligence is inherently adaptive -- animals continually adjust their actions based on environmental feedback. However, creating adaptive artificial intelligence (AI) remains a major chal...

SAFE Labs Starting Aware Fair & Equitable Labs SAFE Labs – a workshop on starting fair, equitable, and successful labs “Starting Aware Fair & Equitable Labs” is a meeting for principal investigators a...