iiinova — where your digital self keeps evolving

Alexandre Piot @alexpiot.bsky.social · 16/09/2026

Wicked new series of evidence-based and community-informed films designed to encourage more nuanced conversations about drugs and the people who use them by @holla-adam.bsky.social. Highly recommend having a watch www.youtube.com/watch?v=Cugw...

youtube.com

Drugs: It's Complicated - Introduction (Film 1)

YouTube video by Drugs: It's Complicated

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Alexandre Piot @alexpiot.bsky.social · 14/09/2026

New in @ijdrugpolicy.bsky.social: xylazine scheduling not linked to fewer xylazine reports but followed by a significant rise in medetomidine, a more potent substitute. It shifts supply composition, not overall burden. More evidence against scheduling. doi.org/10.1016/j.dr...

doi.org

Redirecting

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Alexandre Piot @alexpiot.bsky.social · 11/09/2026

New paper out: loneliness and social isolation predict different patterns of pain medication use transitions in older adults. doi.org/10.1038/s415... with Daisy Fancourt, Mikaela Bloomberg, Andrew Steptoe & Feifei Bu at UCL

doi.org

Loneliness and social isolation as predictors of pain medication use transitions in older adults - Scientific Reports

Scientific Reports - Loneliness and social isolation as predictors of pain medication use transitions in older adults

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George Blackburne @rhizoqualia.bsky.social · 17/08/2026

Small piece in @natmentalhealth.nature.com, calling for greater recognition in the cognitive and computational neurosciences of how weird ligand-receptor interactions are - with @alexpiot.bsky.social, Sunjeev Kamboj and Ravi Das www.nature.com/articles/s44...

nature.com

Embracing pharmacological complexity - Nature Mental Health

Nature Mental Health - Embracing pharmacological complexity

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Alexandre Piot @alexpiot.bsky.social · 13/07/2026

Really encouraging to see the UK and @euda.europa.eu sign a Working Arrangement today. Faster, reciprocal information-sharing on emerging substances and drug threats is exactly the kind of evidence-based, cross-border cooperation that helps protect public health and reduce harm.

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Alexandre Piot @alexpiot.bsky.social · 10/07/2026

@matsouthwell.bsky.social and the Ketamine - Peer Advisory Group (K-PAG) are working hard to provide peer education and promote harm reduction at Beat Herder Fest. for people with k-cramps and ketamine bladder syndrome. Consider donating or sharing this to help fund their work. gofund.me/ddf7d6050

gofund.me

Donate to K-PAG festival intervention at Beat Herder, organized by Mat Southwell

My name is Mat Southwell. I am helping a team of peer workers from the Ketami… Mat Southwell needs your support for K-PAG festival intervention at Beat Herder

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Alexandre Piot @alexpiot.bsky.social · 26/06/2026

Only 26 countries have safer inhalation programmes. In the UK, s9A MDA 1971 still blocks pipe provision. The evidence is there. Policy needs to catch up. Our realist review in @ijdrugpolicy.bsky.social asks how, why & for whom does crack pipe provision work? www.sciencedirect.com/science/arti...

sciencedirect.com

Provision of safer smoking equipment to reduce health harms and enhance service engagement among people who use crack: a realist informed review

Safer smoking equipment interventions for people who smoke crack cocaine have been unevenly implemented globally with most harm reduction policy and p…

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Alexandre Piot @alexpiot.bsky.social · 25/06/2026

Filter mag reporting on the SIPP study, great to see this

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Alexandre Piot @alexpiot.bsky.social · 27/02/2026

I'm thrilled to share my first first-author paper 🎉 We review the synaptic correlates of benzodiazepine tolerance and the molecular mechanisms that drive it. Many thanks to Prof Jovanovic for all her support! 🔗 www.nature.com/articles/s41...

nature.com

Synaptic correlates of benzodiazepine tolerance - Molecular Psychiatry

Molecular Psychiatry - Synaptic correlates of benzodiazepine tolerance

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Reposted by Alexandre Piot

International Journal of Drug Policy @ijdrugpolicy.bsky.social · 01/02/2026

"Pipes as an engagement tool: qualitative findings from a crack equipment and harm reduction training intervention in England" by Casey Sharpe and colleagues (2026) via @ijdrugpolicy.bsky.social . Does your area give out pipes for people who smoke drugs? Link: www.sciencedirect.com/science/arti...

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Alexandre Piot @alexpiot.bsky.social · 29/11/2025

We’re running a short survey on public views about ketamine reclassification and UK drug policy. If you’re 16+ and living in the UK, we’d really appreciate you taking 15 minutes to complete it and share with your networks: www.tinyurl.com/ket-survey

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Alexandre Piot @alexpiot.bsky.social · 06/11/2025

@charlotte2153.bsky.social speaking last night on record high drug-related deaths in the UK: “[The Home Office's stance] is ideological, not evidence-based, which is why I believe the Home Office is fundamentally incapable of dealing with drug deaths and drug harm in our communities.”

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Alexandre Piot @alexpiot.bsky.social · 06/10/2025

Great to see our commentary on stimulant use and nutrition hit the cover of Drink and Drug News magazine this month. Nutrition is often overlooked but crucial issue in harm reduction, time to bring it to the table ! viewer.joomag.com/ddn-october2...

viewer.joomag.com

DDN_October25 DDN October 2025

We have thought-provoking contributions on wellbeing in this issue – mental and physical – including our cover story (p6) in which the team demonstrate that addressing nutritional deficiency should be...

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Addiction journal @addictionjournal.bsky.social · 08/05/2025

The landscape of ketamine use disorder: Patient experiences and perspectives on current treatment options buff.ly/HXPQOvF @bexharding.bsky.social

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Alexandre Piot @alexpiot.bsky.social · 02/04/2025

Our Op-ed on the UK’s drug death crisis, following last week’s Westminster Hall debate we helped secure. Drug-related deaths are a health issue—and should be governed by DHSC. The MDA in its current form is outdated and counterproductive. parliamentnews.co.uk/the-uks-drug...

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Alex Stevens @profalexstevens.bsky.social · 08/01/2025

The #drugpolicyratchet looks set for another turn, even though the ACMD has repeatedly found no evidence that changing the class of a drug has any effect on levels of use. www.theguardian.com/society/2025... #ketamine

theguardian.com

Home Office may reclassify ketamine in response to record levels of use

Illegal use in UK seems to reflect growth of unregulated market in US, where its high-profile users include Elon Musk

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Magdalena Harris @pwud-pride.bsky.social · 04/12/2024

Powerful closing #EHRC2024 plenary. Now the time for "strong language" to achieve, maintain & build #harmreduction with/for our communities. "No more hiding behind rhetoric of 'target' & 'vulnerable' populations". "Zero tolerance on poverty, zero tolerance on inequality, zero tolerance on stigma!"

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Alexandre Piot @alexpiot.bsky.social · 03/12/2024

A Private Member’s Bill proposing changes to how Schedule 2 drugs are amended is set for its second reading this Friday, with the full text now available. This could have significant implications—here’s why it matters… 👇 publications.parliament.uk/pa/bills/cbi...

publications.parliament.uk

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