During cytokinesis in amphibian and echinoderm embryos, propagating waves of Rho activity and F-actin assembly - cortical excitability - are amplified and focused at the equatorial cortex by the mitot...

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In this Perspective, Levin and Wang give a brief history of bacterial growth rate and discuss how it is connected to nutrient availability and macromolecule synthesis, with a focus on (p)ppGpp as a ce...

UNIVERSITY OF MICHIGAN FACULTY POSITION IN CELL & MOLECULAR BIOLOGY AND RELATED FIELDS   The Department of Molecular, Cellular, and Developmental B...

Abstract. Warnowiid dinoflagellates are known for possessing two of the most complex structures known in single cells: multi-projectile nematocysts and the

Cavanaugh et al. show that embryos from aged mice have increased contractility and tissue viscosity on embryonic day 4.5, which leads to poor spreading and attachment. Similar age-associated mechanica...

Cell division must be tightly regulate in time and space. Many bacteria and eukaryotes employ geometry sensing systems to regulate cell division spatiotemporally. However, how archaea ensure they divi...

Researchers in the Coyle Lab have identified unusual growth patterns and their underlying biochemical mechanisms in a single-celled organism on the hunt.

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Extracellular protease activity plays key roles in cell and tissue behavior, processing cell surface proteins, ligands and the extracellular matrix. Extracellular proteases can be subject to complex p...

Bacterial microcompartments (BMCs) are a diverse and widespread class of self-assembling protein-based organelles consisting of a semipermeable protein shell encapsulating an enzymatic core. Isolated ...

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Some microbe species have evolved to stab, bomb, cannibalize, or poison each other. Can we harness their weapons for good?

Nucleosome spacing influences higher-order chromatin fiber organization in vitro but how this relates to cellular chromosome structure remains contentious. To address this, we developed Ligation Analy...