Reposted by Deepak Krishnamurthy
What if you had a light-triggered starting gun for #CRISPR diagnostics? Meet LUCas, a light-controlled #Cas13a system that stays silent until you need it. Now published in @narjournal.bsky.social. Congrats to all the authors!
#moleculardiagnostics academic.oup.com/nar/article/...
academic.oup.com
LUCas: Light-Uncaged Cas13a using photocleavable interfering guide RNAs
Abstract. CRISPR diagnostics enable sensitive detection of infectious diseases, with the RNA endonuclease Cas13a providing specific, amplification-free RNA