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Rohith Rajasekaran

@born2raisecell.bsky.social
17 followers 12 following 1 posts

Postdoc at UCSF: Kole Roybal | Biochemistry PhD student at UW-Madison: Scott Coyle & NIGMIS CBI | former NIH postbac | UMD ‘17

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Reposted by Rohith Rajasekaran
Sternberg Lab @sternberglab.bsky.social · 09/07/2026
1/11 New preprint from the Sternberg lab in collaboration with the Fernández lab! We are excited to share our structure-function study of DRT10, a bacterial defense-associated reverse transcriptase that synthesizes long tandem-repeat DNA.🧵 Read the full story here: www.biorxiv.org/content/10.6...
biorxiv.org
Mechanism of tandem-repeat DNA synthesis by an antiviral reverse transcriptase
Defense-associated reverse transcriptases (DRTs) employ DNA synthesis to protect bacteria against phage infection[1][1],[2][2]. We previously showed that DRT10, a tripartite system comprising an RT, a...
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Scott Coyle @cellraiser.bsky.social · 02/07/2026
Had a blast putting this video abstract together with colleagues for @zjmaggiexu.bsky.social story in @currentbiology.bsky.social on how the "vampire cell" P. collini builds the perfect feeding trap 👀. Be sure to check out the full paper: www.cell.com/current-biol... www.youtube.com/watch?v=Ikzm...
youtube.com
A cellular vampire builds the perfect feeding trap / Curr. Biol., June 24, 2026 (Vol. 36, Issue 14)
YouTube video by Cell Press
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Zhejing (Maggie) Xu @zjmaggiexu.bsky.social · 24/06/2026
Our updated full story on suctorian trap structure adaptation now online in @currentbiology.bsky.social! Huge thanks to Scott and all the co-authors for all the wow moments along the way! Also, if you’d like some new #protist #suctorian, let’s know! (They are surprisingly easy roommates/predators) 🤠
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Rohith Rajasekaran @born2raisecell.bsky.social · 24/06/2026
I am honored and grateful to be selected as a 2026 Jane Coffin Childs Postdoctoral Fellow! I hope to continue doing exciting research!
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Scott Coyle @cellraiser.bsky.social · 24/06/2026
Congratulations to Coyle-Lab alum @born2raisecell.bsky.social (now in Kole Roybal's lab at UCSF) on being selected for this! Very well-deserved -- can't wait to see what you do next
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Reposted by Rohith Rajasekaran
Scott Coyle @cellraiser.bsky.social · 24/06/2026
@zjmaggiexu.bsky.social's story on suctorian trap structure adaptation is now online in @currentbiology.bsky.social , with new evolutionary analyses and modeling! This fall, Maggie will keep exploring predatory protists as a PD in @nbellono.bsky.social group; keep an eye out for her she's amazing!
sciencedirect.com
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Scott Coyle @cellraiser.bsky.social · 16/06/2026
Sub-cellular architectures arise through integrating signaling and structure. @edenchang.bsky.social and @zjmaggiexu.bsky.social show how coupling reaction-diffusion signaling to protein condensation provides a tunable, regulatable landscape for sub-cellular structure www.biorxiv.org/content/10.6...
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Zhejing (Maggie) Xu @zjmaggiexu.bsky.social · 16/06/2026
Watching reaction-diffusion signaling couple to protein condensations feels like opening a new world of exotic subcellular spatial patterning 🌌 huge thanks to the evolving idea started from @edenchang.bsky.social and @cellraiser.bsky.social that make this journey possible and incredibly fun!
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Reposted by Rohith Rajasekaran
edenchang.bsky.social @edenchang.bsky.social · 16/06/2026
Excited to share our new bioRxiv preprint! We introduce RIPPLE, a synthetic platform that couples reaction–diffusion signaling with protein condensation to generate tunable intracellular architectures. Grateful to @zjmaggiexu.bsky.social and @cellraiser.bsky.social. It’s been a rewarding journey.
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UW–Madison Department of Biochemistry @uwbiochem.bsky.social · 06/05/2026
Join us for Zhejing (Maggie) Xu's Ph.D. thesis defense on May 11! As a member of the @cellraiser.bsky.social Lab, Xu studied how predatory protozoa adapt cell morphology to optimize feeding efficiency in response to environmental demands. Learn more: ipib.wisc.edu/2026/04/17/i...
ipib.wisc.edu
IPiB Thesis Defense May 11, 2026: Zhejing “Maggie” Xu
Xu’s research in the Coyle Lab sought to understand how subcellular structures self-organize.
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Reposted by Rohith Rajasekaran
Amy Weeks @amyweeks.bsky.social · 28/04/2026
Excited that our paper on enzymatic bromination of peptides is now online at ACS Chemical Biology! Led by Haley Bridge, we showed that the flavin-dependent halogenase RebH and its variants can be used for late-stage chemoenzymatic diversification of bioactive peptides: pubs.acs.org/doi/10.1021/...
pubs.acs.org
Enzymatic Bromination of Native Peptides for Late-Stage Structural Diversification via Suzuki–Miyaura Coupling
Flavin-dependent halogenases (FDHs) provide a biocatalytic approach for the site-selective halogenation of aromatic compounds, but their use in late-stage functionalization of peptides has remained li...
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Fred Hutch Basic Sciences Division @basicsci.fredhutch.org · 26/02/2026
Huge congratulations to the recipients of the 2026 Harold M. Weintraub Graduate Student Award! These twelve exceptional graduate students exemplify the bold, creative, and pioneering spirit embodied by Dr. Hal Weintraub. www.fredhutch.org/en/news/rele...
Top row, left to right: Keene Abbot, Gabriella Chua, Lifei Jiang, Won Jun Kim, Ruchita Kothari and Ayush Midha. Bottom row, left to right: Rohith Rajasekaran, Yusha Sun, Andrea Terceros, Wendy Valencia Montoya, Zachary Walsh and Peter Yoon.
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Scott Coyle @cellraiser.bsky.social · 27/02/2026
Huge congratulations to my student Rohith Rajasekaran @born2raisecell.bsky.social (now a postdoc in Kole Roybal's lab at UCSF) on being selected for a Weintraub award! Super proud of you and all the work you've done!
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Reposted by Rohith Rajasekaran
Zhejing (Maggie) Xu @zjmaggiexu.bsky.social · 18/11/2025
Thrilled to share our work on the 🔥 single-celled predator Podophrya collini, which rewires its cell morphology to hunt more efficiently. Huge thanks to our amazing team—Amy, Lauren, Omaya, Marine, Mari, and especially Scott—for making this shine! ✨
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Scott Coyle @cellraiser.bsky.social · 18/11/2025
How do cells adapt morphology to function? In a 🔥 preprint by @zjmaggiexu.bsky.social , with @dudinlab.bsky.social and @amyweeks.bsky.social , we identify a self-organizing single-cell morphology circuit that optimizes the feeding trap structure of the suctorian P. collini. 🧵 tinyurl.com/4k8nv926
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Reposted by Rohith Rajasekaran
UW–Madison Department of Biochemistry @uwbiochem.bsky.social · 17/11/2025
Join us for Rohith Rajasekaran's (@born2raisecell.bsky.social) PhD thesis defense on Friday, Nov. 21! Rajasekaran's research was completed in the Coyle Lab (@cellraiser.bsky.social). More info: today.wisc.edu/events/view/...
today.wisc.edu
IPiB Thesis Review: Rohith Rajasekaran | UW–Madison Events Calendar
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Amy Weeks @amyweeks.bsky.social · 13/08/2025
New preprint: we developed a method that uses phosphoproteome-derived peptide libraries (PhosPropels) for deep specificity profiling of phosphatases and phospholyases www.biorxiv.org/content/10.1...
Position-specific frequency matrices can be used to calculate z-scores comparing enzyme-treated and control samples. The z-scores are plotted as heatmaps that represent an enzyme specificity profile.
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Scott Coyle @cellraiser.bsky.social · 04/03/2025
Excited to share a new preprint! Wireless devices use FM modulation to transmit multiplexed noise-resistant data. Led by @born2raisecell.bsky.social, we create a biochemical analogue of this paradigm using genetically encoded oscillators (GEOs) for single-cell FM streaming tinyurl.com/nbs8rw42 🧵
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