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Joël Lemière

@joellemiere.bsky.social
219 followers 305 following 7 posts

Using physics to understand fundamental biology / biophysicist / quantitative biology 🔬 @UCSF. Former PhD @institut_curie

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Joël Lemière @joellemiere.bsky.social · 27/07/2026
New preprint! How does a cell "know" how big to make its nucleus? This has puzzled biologists since the 1800’s. We show the answer is physics: colloid osmotic pressure. 🧵1/5
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GW Gant Luxton @gwgl.bsky.social · 22/07/2026
The nucleolus is the largest condensate in the nucleus and the site where ribosomes are built. It has no membrane. It assembles by phase separation, components demixing from the nucleoplasm into a droplet. So what decides when it forms? 🧵🪱💧 www.biorxiv.org/content/10.6...
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Alexis Lomakin, Ph.D. @alexis-lomakin.bsky.social · 16/12/2025
www.biorxiv.org/content/10.6...
biorxiv.org
Tolerance to the antifungal drug fluconazole is mediated by tuning cytoplasmic fluidity
Treatment failure rates for fungal infections cannot be explained simply by increased rates of drug resistance. Antifungal drug tolerance, the ability of a susceptible isolate to grow in the presence ...
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A. T. Molines @atmolines.bsky.social · 06/12/2025
My former bench mate @joellemiere.bsky.social from the @fredchanglab.bsky.social giving a killer talk about nuclear size regulation in fission yeast at #ASCB #CellBio2025 Stay tuned for the paper to come soon ! Beautiful experimental data falling on the mathematical model, no fit needed 🤩
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Joël Lemière @joellemiere.bsky.social · 25/11/2025
We have a new preprint! 👉 We’ve developed a novel method to induce spindle buckling and utilize this deformation to gain insights into their structural integrity. 👉 A little animated illustration on the bent spindles (green) and our model (blue+pink) where we tune the rigidity of the midzone.
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Hugo Wioland @hugowioland.bsky.social · 15/05/2025
Save the date for the 3rd edition of the Physics & Life days, division of the French Physical Society, October 2-3 at the Institute Jacques Monod, Paris. More info coming soon! Co-organised with Silvia Grigolon & Morgan Chabanon. @sfp-physique.bsky.social @ijmonod.bsky.social
Save the date poster of the Physics & Life days, division of the French Physical Society.
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Adam Schwarz @adamjschwarz.bsky.social · 05/03/2025
French Senator Claude Malhuret: "Washington has become Nero’s court, with an incendiary emperor, submissive courtiers and a jester high on ketamine... We were at war with a dictator, we are now at war with a dictator backed by a traitor."
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Nicolas Minc @minclab.bsky.social · 03/01/2025
Our lab has multiple open positions for post-docs to study the regulation and function of cytoplasm mechanics during embryo development. Details below 👇👇 Please Repost !!! @ijmonod.bsky.social @cnrs.bsky.social
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