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Marqusee Lab @marquseelab.bsky.social · 05/07/2026

Congrats to our talented postdoc @amirbitran.bsky.social for his first preprint in the lab, a collaboration with the Bustamante lab, studying time-resolved protein folding during translation elongation with HDX-MS! Check out the attached manuscript and tutorial for more:

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Marqusee Lab @marquseelab.bsky.social · 17/06/2026

Congrats to our very talented Joshua Morse who recently presented his undergraduate thesis, titled "HDX-MS of Disorder-Containing Complexes Probes Bound State Ensembles", and graduated from UC Berkeley MCB with honors! We are thrilled to have Josh stay in the lab for another year as a PREP scholar

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Marqusee Lab @marquseelab.bsky.social · 05/06/2026

A belated congrats to PhD alum, Sophie Shoemaker on her impressive paper, which recently got published in Science Advances! Sophie managed perform HDX-MS on the SARS-CoV-2 spike protein embedded into membranes in virus-like particles! A truly impressive feat. www.science.org/doi/10.1126/...

science.org

Conformational dynamics of SARS-CoV-2 spike on a membrane reveals the allosteric effects of furin cleavage and the D614G mutation

Conducting HDX-MS on SARS-CoV-2 spike-eVLPs, the effects of natural and engineered features on protein dynamics were determined.

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Marqusee Lab @marquseelab.bsky.social · 22/02/2026

The Marqusee lab is at BPS2026 in San Francisco! Susan gave an invited talk yesterday at the biopolymers in vivo subgroup! Today, Eva Gerber is co chairing the protein dynamics/allostery platform (4 pm rooms 204-206) and giving a flash talk as part of that session at 5:50 pm

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Marqusee Lab @marquseelab.bsky.social · 04/01/2026

The Marqusee lab is at the 2026 protein folding Gordon Research seminar + conference! Amir will be giving a 10 min talk at the GRS today, while Eva will give a 10 min talk at the GRC on Tuesday! Susan will serve as a panelist on today's career panel at the GRS!

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Marqusee Lab @marquseelab.bsky.social · 28/12/2025

Our postdoc Amir Bitran @amirbitran.bsky.social is giving a talk tomorrow at the University of Chile, hosted by Marqusee lab alum and current U. chile faculty Yito Wilson! Feel free to join the talk (which will be largely in Spanish) by scanning the QR code below

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Marqusee Lab @marquseelab.bsky.social · 06/09/2025

Congrats to our current postdoc Amir on his latest publication with the Shakhnovich and Rodnina labs! Check out this thread about their really interesting study, combining all-atom simulation with experiment to reveal a protein's co-translational folding pathway at an atomistic level of detail

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Marqusee Lab @marquseelab.bsky.social · 06/09/2025

So thrilled to share that Susan was selected as a 2025 Protein Society Fellow!

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Marqusee Lab @marquseelab.bsky.social · 26/06/2025

Come check out presentations by the Marqusee lab at the 39th Protein Society Annual Symposium (@proteinsociety.bsky.social). Darren Kahan just gave an awesome talk on his work on IDPs.

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Marqusee Lab @marquseelab.bsky.social · 04/02/2025

Pleased to share a manuscript by our star former grad student, Sara Volz, showing the power of HDX-MS to probe folding intermediates of γD crystallin under native conditions. This approach could shed future light on cataract-linked aggregation. Thanks @alexguseman.bsky.social and the Gronenborn lab

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Marqusee Lab @marquseelab.bsky.social · 30/01/2025

Check out Sophie's new preprint on bioRxiv in collaboration with Magnus Hoffmann's lab where we conduct HDX-MS on SARS-CoV-2 spike proteins displayed on eVLPs to understand the dynamics of natural and engineered variants. 1/7 biorxiv.org/content/10.1...

biorxiv.org

The Interplay of Furin Cleavage and D614G in Modulating SARS-CoV-2 Spike Protein Dynamics

We report a detailed analysis of the full-length SARS-CoV-2 spike dynamics within a native-like membrane environment and variants inaccessible to studies on soluble constructs by conducting hydrogen-d...

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