A new study led by researchers from Ben-Gurion University of the Negev (BGU) reveals that living matter violates previously known physical principles of symmetry when cellular flows form and break dow...

Cavanaugh et al. show that embryos from aged mice have increased contractility and tissue viscosity on embryonic day 4.5, which leads to poor spreading and attachment. Similar age-associated mechanica...

Cell biologists have long known that mechanical forces, such as tension and compression, influence tissue differentiation. Now, advanced methods are letting them observe and manipulate these forces in...

Growing tissues can crack, break, and dissociate to form structures that can later withstand immense forces.

Summary: Tissue material phase transitions are classically thought to regulate tissue deformability. This Review emphasises their unexpected roles in directly influencing growth and patterning signall...

Estimating the dimensionality of the latent representation needed for prediction -- the task-relevant dimension -- is a difficult, largely unsolved problem with broad scientific applications. We cast ...

DynamicAtlas integrates fixed and live imaging data to generate a morphodynamic atlas of Drosophila development.

Epigenetic landscapes were proposed by Waddington as the central concept to describe cell fate dynamics in a locally low-dimensional space. In mode...

Boris Shraiman is awarded the American Physical Society’s Max Delbrück Prize in Biological Physics.

International research team develops mechanical model to explain the shaping of the fruit fly hindgut by forces from neighbouring tissues

Self-organized criticality can occur in cellular systems, but its origins remain unclear. Now it is shown that cytoskeletal criticality is influenced by the F-actin architecture and myosin active stre...

A discovery in Yellowstone National Park led to the development of PCR, the gold-standard COVID-19 tests used to fight the global pandemic.

A large-scale analysis of DNA-bound transcription factors (TFs) shows how the presence of DNA markedly affects the landscape of TF interactions, and identifies composite motifs that are recognized by ...

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The advent of clonal multicellularity is a critical evolutionary milestone, seen often in eukaryotes, rarely in bacteria, and only once in archaea. We show that uniaxial compression induces clonal mul...

Nature Physics - Carcinoma subtypes are normally linked to specific genetic alterations, but tissue mechanical changes also play a role. Now, aberrant morphologies resembling bladder carcinoma are...