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Alex Fellows

@alexfellows1.bsky.social
1.2K followers 1.6K following 12 posts

Post-doc in the Carter lab MRC-LMB, Schiavo lab alumni, #Axonaltransport #Neurons 🧠 #Singlemolecule 🔬

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Reposted by Alex Fellows
Simon Bullock @simonbullock11.bsky.social · 28/09/2026
How are mRNAs linked to molecular motors in mammalian cells? In our new preprint, we show that FXR1/2 are RNA adaptors for the microtubule motor dynein. Our findings have also prompted us to rethink how activating adaptors contribute to motor-based transport (1/n)
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Sami Chaaban @sami-c.bsky.social · 10/09/2026
Excited to share that the Chaaban Lab will be opening in January at the Crick!
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Viji Draviam @viji-draviam.bsky.social · 21/04/2026
@bscb-official.bsky.social Beautiful Cryo-ET talk by Kashish Singh on cytoplasmic lattices in mammalian embryos from @mrclmb.ac.uk at the #DynamicCellVI conference
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Jonny Nixon-Abell @abelljonny.bsky.social · 15/04/2026
Little nudge that early Bird discounts still on for this so if you're planning on coming, would recommend applying asap!
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Meg Clapperton @meganclapperton.bsky.social · 27/03/2026
The last time I attended #FOM, I was presenting my PhD work on human tonsils - this time round, I'll be presenting fun quest in the postdoc journey where we (w/ @jamesdmanton.bsky.social and the LMBs mechanical workshop) designed and validated a novel 4-way image splitter! #FOM2026 Mon 30th @ 4:30
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Carter Lab @carter-lab.bsky.social · 24/03/2026
Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...
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British Society for Cell Biology @bscb-official.bsky.social · 25/02/2026
Have you produced beautiful images as part of your cell biology research? Then enter our image competition! bscb.org/competitions... Deadline 31st March Check out last year's winner 'Brainbow' by Alvaro Castano
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Ines Hahn @exdrososcientia.bsky.social · 25/02/2026
Our article on how GSK3b controls microtubule bundling in axons is live 🎉 Here's our #notthecover attempt www.pnas.org/doi/10.1073/...
Fly primary neurons arranged in a circle, tubulin
 labelled in green, actin in magenta.
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Ines Hahn @exdrososcientia.bsky.social · 18/02/2026
"Your article has been published" 🎉 We found there's a sweet spot of GSK-3β activity required to keep axonal microtubules bundled in 🪰🐀. Too much/little affect how Tau and Shot associate with microtubules leading to microtubules that loose bundling and resemble a bowl of cooked spaghetti 🍝
Images of fly primary neurons that express active or inactive GSK3beta stained for tubulin and a midel summarising how we think Shot and Tau microtubule binding is affected by low, optimal and high kinase activity.
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Ana Dorrego Rivas @adorrego.bsky.social · 08/02/2026
Slowly sketching out the postdoc → PI journey, while still knee-deep in current projects. Would love to hear from neuroscience environments that value ideas, collaboration, and good mentoring. Priority is staying in the UK, but open to opportunities abroad. Tips from those who’ve been there welcome!
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British Society for Cell Biology @bscb-official.bsky.social · 22/01/2026
We are delighted to announce that Eva Simpson from the University of Nottingham has been awarded the 2026 BSCB Raff PhD Medal You can read about Eva's prize-winning PhD work using 3D-CLEM to investigate chromosome ultrastructure here: bscb.org/bscb-phd-awa...
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British Society for Cell Biology @bscb-official.bsky.social · 22/01/2026
We are delighted to announce that @giuliapaci.bsky.social from @ucllifesciences.bsky.social has been awarded the 2026 BSCB Postdoctoral researcher medal You can read about Giulia's work on how tissues withstand mechanical stress here: bscb.org/postdoctoral...
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British Society for Cell Biology @bscb-official.bsky.social · 14/01/2026
One week left to register for our Spring meeting and save £100! Super early booking deadline is 21/1
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British Society for Cell Biology @bscb-official.bsky.social · 18/12/2025
Don't forget to register for our Spring Meeting: Dynamic Cell VI A joint meeting with the @biochemsoc.bsky.social Super early bird registration ends 21st Jan
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Jean-Yves Tinevez @jytinevez.bsky.social · 20/11/2025
We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji. It ships many new features, detailed below, but that are articulated around the following:
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Chris Toseland @christoseland.bsky.social · 05/11/2025
Please repost - Multiple PhDs available www.findaphd.com/phds/project... www.findaphd.com/phds/project... www.findaphd.com/phds/project...
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Brian Carrick @bcarrick.bsky.social · 03/11/2025
The latest from our group (@lapassmore.bsky.social)! Congrats to James and the rest of the authors! Phosphorylation-dependent tuning of mRNA deadenylation rates www.nature.com/articles/s41...
nature.com
Phosphorylation-dependent tuning of mRNA deadenylation rates - Nature Structural & Molecular Biology
Stowell et al. show that the intrinsically disordered region (IDR) of Puf3 binds the Ccr4–Not deadenylase complex using an extended interface. Phosphorylation of the IDR regulates the interaction to t...
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Anne Straube @anne.mechanochemistry.org · 30/10/2025
Get out your calendars! The motors are out of quarantine and we plan to assemble in person on 8th May 2026 at University of Warwick Campus for a fun day on motors and the filaments they walk along. Livestream is planned too. More details on registration, travel bursaries etc. will be revealed soon.
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Anastasia Gusach @g-anastasia.bsky.social · 22/10/2025
Excited to share a new chapter of my scientific journey in Chris Russo's group — developing a way to freeze proteins faster than they diffuse, paving the way for cryo-EM without air–water interface damage.
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Luis Bonet-Ponce @lysoluis.bsky.social · 14/10/2025
🚨 We’re hiring a postdoc! 🚨 Interested in lysosomes, Parkinson’s disease, cell biology, microscopy — or all of the above? Come work with us at the Bonet-Ponce Lab! Reach out directly: luis.bonetponce@osumc.edu Learn more: bonetponcelab.com Let’s chat!
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Matthias Krause @matthias-krause.bsky.social · 10/10/2025
Register for the Dynamic Cell VI conference, Reading, UK, April 2026! This conference focusses on all aspects of cell dynamics, co-organised by @bscb-official.bsky.social and @biochemsoc.bsky.social with @royalmicrosoc.bsky.social and the Chinese Society for Cell Biology. bit.ly/Dynamic-Cell-VI
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British Society for Cell Biology @bscb-official.bsky.social · 22/09/2025
Do you know an outstanding cell biologist? Nominations are open for our 2026 medals: 🔬Hooke Medal for outstanding contribution in cell biology 👩‍🔬Women in Cell Biology medal 🧫 Postdoctoral Researcher medal 🔬Raff PhD medal award Deadline 1st November
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Dan Bose @danbose.bsky.social · 06/10/2025
Great review of the super #NeuroBioUK2025 meeting in September. Well done to everyone who organised it @exdrososcientia.bsky.social @alexfellows1.bsky.social and @dozenoaks.bsky.social for putting together such a great meeting for the community! 👏🧠🔬 tinyurl.com/4jn7yrmt roll on next year!
tinyurl.com
NeuroBio UK 2025: Insights, Innovation, and Inspiration in Neuroscience - FocalPlane
NeuroBio UK 2025: Insights, Innovation, and Inspiration in Neuroscience -
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(GIRISH)MALI LAB @dyneinassembly.bsky.social · 29/09/2025
Happy to share the inaugural paper from the lab. We describe a molecular mechanism for the activation of outer dynein arm motors that power the vital motion of cilia. Open access link below: www.nature.com/articles/s41... Here's a cool animated summary
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Sarah Cohen @cohenlaboratory.bsky.social · 17/09/2025
Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou
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Ali Twelvetrees @dozenoaks.bsky.social · 12/09/2025
Poster boards are ready and waiting for #NeuroBioUK - let’s get this science party started 🥳
The poster hall at the National STEM learning centre with astronauts suspended from the ceiling.
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Alex Fellows @alexfellows1.bsky.social · 11/09/2025
In York for #NeuroBioUk25! As you can tell from my face..I'm excited!
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Women in Neuroscience UK @womeninneurouk.bsky.social · 08/09/2025
🚨WiNUK Day 2026 is coming to Birmingham this April!🚨 This year’s theme is neurodiversity🧠🌈 🗓️ Happening during #AutismAwarenessMonth
🗣️ Open call for talks, posters & panels (all genders welcome!)
📅 Deadline: Sun 14 Sept #WiNUKDay2026 #Neurodiversity #WomenInSTEM
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James N. Sleigh @jamessleigh.bsky.social · 09/09/2025
Beautiful data from @dvillarroelc.bsky.social showing a key role for TBK1 in #AxonalTransport of signalling endosomes: www.biorxiv.org/content/10.1... @uclqsion.bsky.social @mndassoc.bsky.social #ALS #MND
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Journal of Cell Biology @jcb.org · 03/09/2025
Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, execution, and analysis of experiments, and the subsequent communication of their results to their peers. 👉 rupress.org/jcb/collecti... #Reproducibility
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Ali Twelvetrees @dozenoaks.bsky.social · 28/08/2025
The programme is up for #NeuroBioUK25 - take a look! And don’t forget to register by the 3rd of September…. neurobiouk.sites.sheffield.ac.uk/programme
neurobiouk.sites.sheffield.ac.uk
NeuroBioUK - Programme
9 AM Arrival, registration & coffee Session 1: Organelle and synaptic signalling Session Chair: 9:45 AM Introduction 9:50 AM Sally Horton, The Francis Crick Institute, "CDKL5 in synaptic formation,...
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Alex Fellows @alexfellows1.bsky.social · 18/08/2025
Do you love the brain? So do we! Poster and registration deadline is the 3rd September for NeurobioUK 2025. We have an awesome line up of speakers this year. Come and join us in York! neurobiouk.sites.sheffield.ac.uk/registration
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James N. Sleigh @jamessleigh.bsky.social · 12/08/2025
It's an honour to become a Professor at such a wonderful institution @uclqsion.bsky.social @uclbrainscience.bsky.social. The @uclqsneuromuscular.bsky.social is an amazing place to work and I couldn't have done it without my fantastic team, mentors and collaborators: www.ucl.ac.uk/brain-scienc...
ucl.ac.uk
Senior Academic and Early Career Promotions 2024-25
Huge congratulations to the UCL Queen Square Institute of Neurology staff who have been awarded a promotion in this year's promotions round.
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Carter Lab @carter-lab.bsky.social · 05/08/2025
Excited to share our latest work with @simonbullock11.bsky.social! We looked at how diverse mRNAs get selected for subcellular localization and it turns out that a single protein can recognize different RNA elements using shared features that weren’t apparent before. www.biorxiv.org/content/10.1...
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Simon Bullock @simonbullock11.bsky.social · 05/08/2025
Our latest work, in collaboration with the terrific @kashishsingh.bsky.social in the Carter lab @mrclmb.bsky.social is out. So proud of this study and everyone involved...
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Martin Pacesa @martinpacesa.bsky.social · 01/08/2025
Great talk by @sami-c.bsky.social about the proper use and caveats of AlphaFold2/3 predictions, highly recommended to watch www.youtube.com/watch?v=z7vy...
youtube.com
Structure Prediction and Design using AlphaFold – Sami Chaaban
YouTube video by MRC Laboratory of Molecular Biology
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Fran Bottanelli @franbottanelli.bsky.social · 09/07/2025
Full lineup now announced for the 2026 #JCSimaging! Everything from #cryo #CLEM #superresolution #ExM #tissueimaging and more! Save the date and spread the word!
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Ana Dorrego Rivas @adorrego.bsky.social · 08/07/2025
Really, really amazing conference. We went last year and the scientific programme and atmosphere were incredible! I 100% recommend attending + submitting an abstract for a talk - spread the word! 🧠
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Alex Fellows @alexfellows1.bsky.social · 08/07/2025
Neurobiologists 🧠!! If you want to give a talk at NeurobioUK this year, the deadline is the 1st August. Don't miss your chance to be part of an absolutely awesome meeting.
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Ali Twelvetrees @dozenoaks.bsky.social · 06/06/2025
Registration is now open for NeuroBioUK 2025! This year we're looking forward to hearing from our plenary speaker @cathyabbott.bsky.social. As ever, all other talks chosen from submitted abstracts so get submitting - we can't wait to see you there! neurobiouk.sites.sheffield.ac.uk/registration
An image montage advertising NeuroBioUK - 12th of September 2025 in York. The image is York cathedral superimposed over a fluorescent cortex mouse section coloured to look a bit like a dawn sky.
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Nicol Birsa @nicolbirsa.bsky.social · 18/06/2025
Very excited to share our latest preprint! We looked at loss and gain of function, innervation, reinnervation, and in vivo axonal transport in a FUS-ALS mouse model! www.biorxiv.org/content/10.1... @uclqsion.bsky.social @beccasimkin.bsky.social @andrewtosolini.bsky.social @frattalab.bsky.social
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Mothers in Science @mothersinsci.bsky.social · 10/06/2025
We’ve been quietly working on something BIG… Launching June 16th! 🎉 If you’re a father in STEMM (or know one) who wants to make change & promote caregiving inclusion in the workplace, get in touch! #FathersWhoCare #StrongEnoughToCare #AcademicDads
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Ines Hahn @exdrososcientia.bsky.social · 06/06/2025
Registration is open for the third #NeuroBioUK!! @dozenoaks.bsky.social @alexfellows1.bsky.social and I are excited to see you again in York!
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Journal of Cell Science @jcellsci.bsky.social · 19/05/2025
After the success of our 2023 Imaging Cell Dynamics conference, we’ll be hosting a second #JCSImaging meeting in 2026, organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social‬, @drmichaelway.bsky.social‬ & Giulia Zanetti. To register your interest: www.biologists.com/meetings/jcs...
Journal of Cell Science Meeting 2026 
Imaging Cell Dynamics
Date: 11 – 14 May 2026
Venue: Montanyà Hotel, Catalonia, Spain
Register your interest
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jwelburn.bsky.social @jwelburn.bsky.social · 13/05/2025
This year's poster winners with the Microtubule meeting organizers. Well done to all poster presenters for showcasing some great science!
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Ferdos Abid Ali @abidalilab.bsky.social · 24/04/2025
Great to see our story on dynein & kinesin co-dependence published www.nature.com/articles/s41..., and absolutely chuffed that it's made the front cover (thanks NSMB!). A brilliant News & Views too by Steven Markus www.nature.com/articles/s41.... Collab between @carter-lab.bsky.social & Straube lab🔬
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Steffen Scholpp @scholpplab.bsky.social · 24/04/2025
We are happy to announce that @biologists.bsky.social will sponsor the first UK Zebrafish Meeting @lsiexeter.bsky.social. Are you a PhD student/ECR who wants to present your work? Talk or poster? 👍 Deadline for the early bird registration is 15/5/. So, be quick! www.exeter.ac.uk/research/ins....
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jwelburn.bsky.social @jwelburn.bsky.social · 20/04/2025
The Microtubule meeting program is out and is looking great this year again! biology.ed.ac.uk/microtubule/...
biology.ed.ac.uk
9th Microtubule Meeting UK
Program for the meeting
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Alex Fellows @alexfellows1.bsky.social · 11/04/2025
Join Adam's Lab! He is an amazing scientist and the project is so cool!
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Mark Dodding @markdodding.bsky.social · 10/04/2025
New preprint on kinesin inhibition and activation - collaborative effort across Bristol Biochem and Chemistry with Woolfson and Schaffizel labs and JJ Phillips in Exeter 1/2 www.biorxiv.org/content/10.1...
biorxiv.org
Molecular mechanism for cargo-mediated initiation of kinesin-1 activation
Kinesin-1 is a dynamic heterotetrameric assembly of two heavy and two light chains (KHC and KLC) that mediates microtubule-based intracellular transport of many different cargoes. The complex adopts a...
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