Sami Chaaban @sami-c.bsky.social · 10/09/2026Excited to share that the Chaaban Lab will be opening in January at the Crick! 77514
Reposted by Sami ChaabanAlister Burt @alisterburt.bsky.social · 04/05/2026tl;dr: MissAlignment learns to score misalignment then wiggles your alignments around to reduce that misalignment -> no more misalignment = high res STA 🌟 Watching @martenchaillet.bsky.social chip away at this was a real privilege! I’m excited to see this out and what you all will do with it 🙃 1479
Reposted by Sami ChaabanSimon Bullock @simonbullock11.bsky.social · 18/03/2026Delighted to announce the posting of our latest preprint, which links stress-induced relocalisation of multiple organelles by dynein to adaptive changes in gene expression in the nucleus (1/n) 🧵 www.biorxiv.org/content/10.6... 14219
Reposted by Sami ChaabanSjors Scheres @sjorsscheres.bsky.social · 18/03/2026You can download RELION-5.1 from github.com/3dem/relion (branch ver5.1) Note that the beautiful startup image of dynein:dynactin on a microtubule was provided by Sami Chabaan from the @carter-lab.bsky.social. 🤗github.comGitHub - 3dem/relion: Image-processing software for cryo-electron microscopyImage-processing software for cryo-electron microscopy - 3dem/relion 1113
Reposted by Sami ChaabanSjors Scheres @sjorsscheres.bsky.social · 18/03/2026We're excited to announce the beta-release of #RELION-5.1! 🥳 This release has important updates on our #amyloid processing pipeline, as described in this preprint: doi.org/10.64898/202... There are also some tweaks for #teamtomo. #OpenSoftwareAcceleratesScience 314947
Reposted by Sami ChaabanKelly Nguyen @kellythd-nguyen.bsky.social · 22/12/2025We have an opening for a research support officer. Come and join us! Please share. 01722
Reposted by Sami ChaabanDepartment of Biology, ETH Zurich @eth-dbiol.bsky.social · 02/12/2025Congrats to Michal Wieczorek (wieczorekgroup.ethz.ch/research.html, IMBB) on being selected as an @embo.org Young Investigator. The 2024 cohort highlights excellence across the life sciences, and this recognition reflects Michal’s outstanding scientific contributions. 1103
Reposted by Sami ChaabanAlan Brown @alanbrownhms.bsky.social · 18/11/2025Our lab is seeking a Postdoctoral Fellow. The position is intentionally broad, as we are looking for outstanding researchers from diverse scientific backgrounds to advance our understanding of cilia and ciliopathies: academicpositions.harvard.edu/postings/15526academicpositions.harvard.eduHMS - Postdoctoral Fellow in BCMP, Brown LabWe invite applicants for a postdoctoral fellow position in the Brown lab at Harvard Medical School in Boston, Massachusetts. The Brown lab uses structural, biophysical, and biochemical approaches to d... 02219
Reposted by Sami ChaabanTanmay Bharat @tbharat-lab.bsky.social · 07/11/2025An Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1... 10387168
Reposted by Sami ChaabanMax Wilkinson @maxewilkinson.bsky.social · 31/10/2025The Wilkinson Lab is open for science! @mskcancercenter.bsky.social 🧬We'll be finding funky new RNA biology, mainly by looking at reverse transcriptases (i.e. the Best Enzymes In The World)🧬 annnd: I'm hiring - come join! Especially postdocs and PhD students - please get in touch (NYC is great)wilkinsonlab.bioWilkinson LabWe discover and study reverse transcriptases 59946
Reposted by Sami ChaabanHarry Low’s Lab @lowlab.bsky.social · 29/10/2025Please RT. Post-doc opportunity alert! 💥 closing 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems. For more details and to apply please see www.imperial.ac.uk/jobs/search-... 14940
Reposted by Sami ChaabanSjors Scheres @sjorsscheres.bsky.social · 29/10/2025We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated. mrc.tal.net/vx/appcentre...mrc.tal.netQuick Check Needed 26457
Reposted by Sami ChaabanOli Clarke @olibclarke.bsky.social · 13/09/2025This one is a bit of a departure from the usual and definitely a work in progress! We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below. Read on for details... 1/x 2026782
Reposted by Sami ChaabanCarter Lab @carter-lab.bsky.social · 05/08/2025Excited to share our latest work with @simonbullock11.bsky.social! We looked at how diverse mRNAs get selected for subcellular localization and it turns out that a single protein can recognize different RNA elements using shared features that weren’t apparent before. www.biorxiv.org/content/10.1... 414346
Reposted by Sami ChaabanFerdos Abid Ali @abidalilab.bsky.social · 24/04/2025Great to see our story on dynein & kinesin co-dependence published www.nature.com/articles/s41..., and absolutely chuffed that it's made the front cover (thanks NSMB!). A brilliant News & Views too by Steven Markus www.nature.com/articles/s41.... Collab between @carter-lab.bsky.social & Straube lab🔬 1268
Reposted by Sami ChaabanWieczorek Lab @mike-wieczorek.bsky.social · 22/03/2025Happy to have contributed a small part to this exciting story about the ancestors of eukaryotic tubulin in Asgard archaea. Congratulations to all the co-authors! 1112
Reposted by Sami ChaabanVladimir Volkov 🇺🇦 @vladimirvolkov.bsky.social · 21/03/2025Microtubules in Asgard archaea 🤩🤩 www.cell.com/cell/fulltex...cell.comMicrotubules in Asgard archaeaDiscovery of heterodimeric, microtubule-forming tubulins in Asgard archaea, the closest known relatives of eukaryotes, reveals snapshots of microtubule evolution. 44010
Reposted by Sami ChaabanJavier Espadas @javierespadas.bsky.social · 11/02/2025Extremely happy to see our work finally out!🎉 Great collaboration between @rouxlab.bsky.social @buzzbaum.bsky.social labs and a real pleasure to work and share co-first authorship with incredible scientists and friends @diorgeps.bsky.social @sami-c.bsky.social. Big thanks to the rest of the authors! 0268
Reposted by Sami ChaabanMRC Laboratory of Molecular Biology @mrclmb.ac.uk · 11/02/2025New research on ancient Asgard archaeal ESCRT-III proteins reveals evolutionary secrets of membrane remodelling. Diorge Souza, Javier Espadas and Sami Chaaban, investigated the ESCRT-III proteins with Buzz Baum and Aurelien Roux. Read more: www2.mrc-lmb.cam.ac.uk/asgard-archa... #LMBResearch (1/2) 13312
Reposted by Sami ChaabanTim Stearns @stearnslab.bsky.social · 04/12/2024How do great discoveries sometimes come from unexpected findings? It’s right there in the first paragraph of Fleming’s paper: a contaminated plate led to the discovery of penicillin. Much work was required to turn the discovery into practice, but this simple observation started it all. 02112
Reposted by Sami ChaabanJessica Cross @jessicacross.bsky.social · 28/11/2024Please share this PhD opportunity in my new lab in Bristol, using protein design/ engineering to understand and build molecular motors to control intracellular transport. Working with @markdodding.bsky.social and Prof Dek Woolfson. www.findaphd.com/phds/project... www.swbio.ac.uk/biomolecular... 35638
Reposted by Sami ChaabanFerdos Abid Ali @abidalilab.bsky.social · 27/11/2024If you’re interested in how molecular motors coordinate to power intracellular trafficking events (e.g. endocytosis), I’ve got a PhD position available to study this at vibrant Bristol uni. In this project, we will capture highly dynamic events by #cryoEM, single molecule imaging & cell biology. 🔬❄️🧪 15430
Reposted by Sami Chaabansamlacey.bsky.social @samlacey.bsky.social · 18/11/2024Our review of Intraflagellar transport is out now! We cover lots of the recent advances in our understanding of IFT, and where we think there are still some gaps. www.nature.com/articles/s41...nature.comThe intraflagellar transport cycle - Nature Reviews Molecular Cell BiologyIntraflagellar transport (IFT) ensures delivery of selected proteins into cilia. The IFT protein complexes IFT-A and IFT-B polymerize at the base of the cilium to form an anterograde train that facili... 28828
Reposted by Sami ChaabanSjors Scheres @sjorsscheres.bsky.social · 17/11/2024FOMO? The below is really good to find people your followers are following, but you are not. #OpenSoftwareAcceleratesScience bsky-follow-finder.theo.iobsky-follow-finder.theo.ioBluesky Network AnalyzerFind accounts that you don't follow (yet) but are followed by lots of accounts that you do follow. 1146
Reposted by Sami ChaabanUtz Ermel @uermel.bsky.social · 16/11/2024Using interactive web-viz for sharing results lossless is always an option! In this case it's as easy as clicking "View Tomogram" here: cryoetdataportal.czscience.com/runs/14185cryoetdataportal.czscience.comRun 293