Sign in

Sami Chaaban

@sami-c.bsky.social
203 followers 183 following 2 posts

Group Leader at the Francis Crick Institute starting January 2027. Currently postdoc in the Carter Lab (MRC-LMB), previously PhD in the Brouhard Lab (McGill University) sami-chaaban.github.io

PostsRepliesMedia
Sami Chaaban @sami-c.bsky.social · 10/09/2026
Excited to share that the Chaaban Lab will be opening in January at the Crick!
77514
Reposted by Sami Chaaban
Alister Burt @alisterburt.bsky.social · 04/05/2026
tl;dr: MissAlignment learns to score misalignment then wiggles your alignments around to reduce that misalignment -> no more misalignment = high res STA 🌟 Watching @martenchaillet.bsky.social chip away at this was a real privilege! I’m excited to see this out and what you all will do with it 🙃
1479
Reposted by Sami Chaaban
Simon Bullock @simonbullock11.bsky.social · 18/03/2026
Delighted to announce the posting of our latest preprint, which links stress-induced relocalisation of multiple organelles by dynein to adaptive changes in gene expression in the nucleus (1/n) 🧵 www.biorxiv.org/content/10.6...
14219
Reposted by Sami Chaaban
Sjors Scheres @sjorsscheres.bsky.social · 18/03/2026
You can download RELION-5.1 from github.com/3dem/relion (branch ver5.1) Note that the beautiful startup image of dynein:dynactin on a microtubule was provided by Sami Chabaan from the @carter-lab.bsky.social. 🤗
github.com
GitHub - 3dem/relion: Image-processing software for cryo-electron microscopy
Image-processing software for cryo-electron microscopy - 3dem/relion
1113
Reposted by Sami Chaaban
Sjors Scheres @sjorsscheres.bsky.social · 18/03/2026
We're excited to announce the beta-release of #RELION-5.1! 🥳 This release has important updates on our #amyloid processing pipeline, as described in this preprint: doi.org/10.64898/202... There are also some tweaks for #teamtomo. #OpenSoftwareAcceleratesScience
314947
Reposted by Sami Chaaban
Kelly Nguyen @kellythd-nguyen.bsky.social · 22/12/2025
We have an opening for a research support officer. Come and join us! Please share.
01722
Reposted by Sami Chaaban
Department of Biology, ETH Zurich @eth-dbiol.bsky.social · 02/12/2025
Congrats to Michal Wieczorek (wieczorekgroup.ethz.ch/research.html, IMBB) on being selected as an @embo.org Young Investigator. The 2024 cohort highlights excellence across the life sciences, and this recognition reflects Michal’s outstanding scientific contributions.
1103
Reposted by Sami Chaaban
Alan Brown @alanbrownhms.bsky.social · 18/11/2025
Our lab is seeking a Postdoctoral Fellow. The position is intentionally broad, as we are looking for outstanding researchers from diverse scientific backgrounds to advance our understanding of cilia and ciliopathies: academicpositions.harvard.edu/postings/15526
academicpositions.harvard.edu
HMS - Postdoctoral Fellow in BCMP, Brown Lab
We invite applicants for a postdoctoral fellow position in the Brown lab at Harvard Medical School in Boston, Massachusetts. The Brown lab uses structural, biophysical, and biochemical approaches to d...
02219
Reposted by Sami Chaaban
Tanmay Bharat @tbharat-lab.bsky.social · 07/11/2025
An Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...
10387168
Reposted by Sami Chaaban
Max Wilkinson @maxewilkinson.bsky.social · 31/10/2025
The Wilkinson Lab is open for science! @mskcancercenter.bsky.social 🧬We'll be finding funky new RNA biology, mainly by looking at reverse transcriptases (i.e. the Best Enzymes In The World)🧬 annnd: I'm hiring - come join! Especially postdocs and PhD students - please get in touch (NYC is great)
wilkinsonlab.bio
Wilkinson Lab
We discover and study reverse transcriptases
59946
Reposted by Sami Chaaban
Harry Low’s Lab @lowlab.bsky.social · 29/10/2025
Please RT. Post-doc opportunity alert! 💥 closing 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems. For more details and to apply please see www.imperial.ac.uk/jobs/search-...
14940
Reposted by Sami Chaaban
Sjors Scheres @sjorsscheres.bsky.social · 29/10/2025
We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated. mrc.tal.net/vx/appcentre...
mrc.tal.net
Quick Check Needed
26457
Reposted by Sami Chaaban
Oli Clarke @olibclarke.bsky.social · 13/09/2025
This one is a bit of a departure from the usual and definitely a work in progress! We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below. Read on for details... 1/x
2026782
Reposted by Sami Chaaban
Carter Lab @carter-lab.bsky.social · 05/08/2025
Excited to share our latest work with @simonbullock11.bsky.social! We looked at how diverse mRNAs get selected for subcellular localization and it turns out that a single protein can recognize different RNA elements using shared features that weren’t apparent before. www.biorxiv.org/content/10.1...
414346
Reposted by Sami Chaaban
Ferdos Abid Ali @abidalilab.bsky.social · 24/04/2025
Great to see our story on dynein & kinesin co-dependence published www.nature.com/articles/s41..., and absolutely chuffed that it's made the front cover (thanks NSMB!). A brilliant News & Views too by Steven Markus www.nature.com/articles/s41.... Collab between @carter-lab.bsky.social & Straube lab🔬
1268
Reposted by Sami Chaaban
Wieczorek Lab @mike-wieczorek.bsky.social · 22/03/2025
Happy to have contributed a small part to this exciting story about the ancestors of eukaryotic tubulin in Asgard archaea. Congratulations to all the co-authors!
1112
Reposted by Sami Chaaban
Vladimir Volkov 🇺🇦 @vladimirvolkov.bsky.social · 21/03/2025
Microtubules in Asgard archaea 🤩🤩 www.cell.com/cell/fulltex...
cell.com
Microtubules in Asgard archaea
Discovery of heterodimeric, microtubule-forming tubulins in Asgard archaea, the closest known relatives of eukaryotes, reveals snapshots of microtubule evolution.
44010
Reposted by Sami Chaaban
Javier Espadas @javierespadas.bsky.social · 11/02/2025
Extremely happy to see our work finally out!🎉 Great collaboration between @rouxlab.bsky.social @buzzbaum.bsky.social labs and a real pleasure to work and share co-first authorship with incredible scientists and friends @diorgeps.bsky.social @sami-c.bsky.social. Big thanks to the rest of the authors!
0268
Reposted by Sami Chaaban
MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 11/02/2025
New research on ancient Asgard archaeal ESCRT-III proteins reveals evolutionary secrets of membrane remodelling. Diorge Souza, Javier Espadas and Sami Chaaban, investigated the ESCRT-III proteins with Buzz Baum and Aurelien Roux. Read more: www2.mrc-lmb.cam.ac.uk/asgard-archa... #LMBResearch (1/2)
Evolution, structure and membrane remodelling function of the ESCRT-III superfamily in eukaryotes and their closest relatives Asgard archaea. The two subfamilies, B-type and A-type, have distinct structural properties to perform sequential steps of the membrane remodelling pathway.
13312
Reposted by Sami Chaaban
Tim Stearns @stearnslab.bsky.social · 04/12/2024
How do great discoveries sometimes come from unexpected findings? It’s right there in the first paragraph of Fleming’s paper: a contaminated plate led to the discovery of penicillin. Much work was required to turn the discovery into practice, but this simple observation started it all.
02112
Reposted by Sami Chaaban
Jessica Cross @jessicacross.bsky.social · 28/11/2024
Please share this PhD opportunity in my new lab in Bristol, using protein design/ engineering to understand and build molecular motors to control intracellular transport. Working with @markdodding.bsky.social and Prof Dek Woolfson. www.findaphd.com/phds/project... www.swbio.ac.uk/biomolecular...
35638
Reposted by Sami Chaaban
Ferdos Abid Ali @abidalilab.bsky.social · 27/11/2024
If you’re interested in how molecular motors coordinate to power intracellular trafficking events (e.g. endocytosis), I’ve got a PhD position available to study this at vibrant Bristol uni. In this project, we will capture highly dynamic events by #cryoEM, single molecule imaging & cell biology. 🔬❄️🧪
This scheme shows the cargo adaptor FHF in the middle with arrows pointing to distinct microtubule and actin-based motors (dynein-dynactin, KIFC1, KIF1C and myosins V, IX and X as well as Tropomyosin 1). It also shows a link to Rab5 marked early endosomes. The hypothesis is that FHF coordinates multi motor binding at the early stages of endocytosis. The PhD project would address the hierarchy of motor binding and how these motors coordinate to allow the newly formed vesicle to transition from the actin to MT cytoskeletal network.
15430
Reposted by Sami Chaaban
samlacey.bsky.social @samlacey.bsky.social · 18/11/2024
Our review of Intraflagellar transport is out now! We cover lots of the recent advances in our understanding of IFT, and where we think there are still some gaps. www.nature.com/articles/s41...
nature.com
The intraflagellar transport cycle - Nature Reviews Molecular Cell Biology
Intraflagellar transport (IFT) ensures delivery of selected proteins into cilia. The IFT protein complexes IFT-A and IFT-B polymerize at the base of the cilium to form an anterograde train that facili...
28828
Reposted by Sami Chaaban
Sjors Scheres @sjorsscheres.bsky.social · 17/11/2024
FOMO? The below is really good to find people your followers are following, but you are not. #OpenSoftwareAcceleratesScience bsky-follow-finder.theo.io
bsky-follow-finder.theo.io
Bluesky Network Analyzer
Find accounts that you don't follow (yet) but are followed by lots of accounts that you do follow.
1146
Reposted by Sami Chaaban
Utz Ermel @uermel.bsky.social · 16/11/2024
Using interactive web-viz for sharing results lossless is always an option! In this case it's as easy as clicking "View Tomogram" here: cryoetdataportal.czscience.com/runs/14185
cryoetdataportal.czscience.com
Run
293