Join leading experts at the 10th FASEB Lipid Droplets Science Research Conference to explore lipid metabolism, disease links, and new research.

Hosted by ASCB’s Molecular Biology of the Cell (MBoC) journal, this special event highlights cutting-edge research from the MBoC Special Issue “Quantitative Cell Biology,” which features more than 200 publications in this rapidly advancing field. The program includes a keynote presentation by former ASCB President Jennifer Lippincott-Schwartz, followed by lightning talks from early-career scientists whose exceptional work appears in the issue. Attendees will…

In vivo regulation of neuronal lipid droplet formation mediates whole-body energy homeostasis in a sex-specific manner in Drosophila and mice.

Lennartz et al. introduce a correlative light and electron microscopy workflow, Lipid-CLEM, combining near-native lipid probes and on-section labelling via click chemistry. Lipid-CLEM quantitatively a...

Using single-cell tissue imaging and spatial proteomics to study mitochondria–lipid droplet coupling in hepatocytes, PLIN5 phosphorylation is identified as a mediator of lipid flux and nutrient stress...

CRISPR–Cas9 screening identifies CLCC1 as a factor that increases neutral lipid flux to prevent hepatic steatosis and promotes nuclear pore complex assembly by promoting membrane bending and fusi...

Lipid droplets have key roles in energy storage and lipid metabolism. This Review discusses tools used for assessing lipid droplet heterogeneity, and how their heterogeneous composition and interactio...

Nature Reviews Molecular Cell Biology, Published online: 15 January 2026; doi:10.1038/s41580-025-00945-xLipid droplets have key roles in energy storage and lipid metabolism. This Review discusses tools used for assessing lipid droplet heterogeneity, and how their heterogeneous composition and interactions with other organelles influence physiology and contribute to disease.

The terror attack on Bondi Beach was an atrocity tolerated into being, writes Ayaan Hirsi Ali.

Ralhan et al. show that ApoE2 and ApoE3 Christchurch on lipid particles efflux oxidized phospholipids from neurons via the ABCA7 transporter. This reduces the burden of oxidized lipids, which improves lysosomal function and protects neurons from ferroptosis.

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