The primary cilium dynamically assembles and disassembles while maintaining structural stability and tightly regulated length, but the mechanisms that control this remain unclear. This study shows tha...

Legal et al. resolve the ciliary tip central pair structure, revealing novel proteins that stabilize its unique form. They show how the protein SPEF1 binds the microtubule seam and stabilizes the tip ...

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Kinesin-1 is a dynamic heterotetrameric assembly of two heavy and two light chains (KHC and KLC) that mediates microtubule-based intracellular transport of many different cargoes. The complex adopts a...

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Although we are all dedicated to conducting high-quality, cutting-edge research in the basic and applied biomedical sciences, it is important to acknowledge the environmental impact of our work. The b...