iiinova — where your digital self keeps evolving

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shenvi.bsky.social @shenvi.bsky.social · 01/10/2026

A few folks have asked how I make molecular animations from ChemDraw. Sadly, the answer has been “the old-fashioned way,” frame by frame. This was too slow. So I worked with Claude Science to create a webpage that animates your ChemDraws. Give it a try: rshenvi.github.io/cdxmorph/

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Kimberly Beatty @beattylab.bsky.social · 28/09/2026

Please share: OHSU is hiring an Assistant Prof. in the Dept. of Chemical Physiology & Biochemistry. We are looking for a chemical biologist who will apply novel chemical tools in physiological systems. Apply online: www.ohsu.edu/human-resour... (Job # 2026-41667).

ohsu.edu

OHSU Faculty, Physician and Academic Jobs in Oregon

Find higher education faculty, physician and research jobs and build your academic health career at OHSU in Portland, Oregon.

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Rasmus Jensen @rasmusjensen.bsky.social · 25/09/2026

🎉 Out today in Cell: the paper I've been looking forward to sharing for a long time 🎉 We used cryo-ET to find a molecular machine nobody knew existed on the surface of a minimal bacterium, and worked out what it does. 🧵(1/7) #TeamTomo #cryoET

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Cathy Spangler @cathyspangler.bsky.social · 22/09/2026

I'm excited to share our new preprint, where we show that fine-tuning gold nanoparticle conjugation to different Fab structural elements can produce powerful, rigidly coupled, labeling tools for in-situ cryo-ET. Take a look if you want to see an AuNP in an EM map!🔬🧠 www.biorxiv.org/content/10.6...

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Structura Biotechnology @structurabio.bsky.social · 16/09/2026

🚀 Register now for the 2026 Stanford-SLAC CryoEM Center (S2C2) Data Processing Workshop, December 9-11! We’re excited to contribute as #CryoSPARC instructors to this hybrid workshop, together with instructors from CryoDRGN, EMAN2 and AreTomo! More info and registration 👉 bit.ly/4gXbnXd

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Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · 13/09/2026

Fold Spacer lets you fly through protein structures (Weekend project #2). It’s my first game: I originally set out to build a racer with structures as the tracks, but was a little too crazy. So it became this instead. You can upload your own structures. 🌐 martin-steinegger.github.io/Fold-Spacer/

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Anh Hoang Le, PhD 🏳️‍🌈🏴󠁧󠁢󠁳󠁣󠁴󠁿🇻🇳 @anhhle2702.bsky.social · 07/09/2026

Very happy to share my postdoc paper is out now in @natcellbio.nature.com titled "Tissue flow acts as a guidance cue for immune cell polarization and directional migration". If you love imaging and immune cells, this is for you! #microscopymonday www.nature.com/articles/s41... A 🧵: 1/n

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Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 03/09/2026

When I was volunteering at the COVID19 vaccine POD in 2021, people would say over and over again that they were getting vaccinated for the people they love. Last year, only 17.5% of American adults got the COVID19 vaccine. Please get one for the people you love. 💕

Photo of a brunette with a braid in her hair, standing in front of a sign that says Vaccinated with a count of 30,000.

She is wearing glasses, a Sun Studio t-shirt, and an orange high vis vest.

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Jonathan Pruneda @jnpruneda.bsky.social · 22/08/2026

WE'RE HIRING! Thanks to some recent successes with NIH funding, we're seeking two new postdoctoral scholars to join our team. See below for details. Please share widely and feel free to reach out with any questions!

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Edward T Eng @edwardteng.bsky.social · 21/08/2026

The next #CryoEM Current Practices Webinar will be a career panel with former users and trainees of the nIH sponsored national cryoEM service centers 8/27/2026 at 12 PM ET / 9AM PT Registration is at no-cost, but sign-up is required: us02web.zoom.us/webinar/regi...

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Reichow Lab @reichowlab.bsky.social · 13/08/2026

Long-timescale simulations reveal multi-ion flux through wide pore gap junction channels -– and an unexpected transition involving loop–NT domain interactions that suggest a dynamic ensemble of micro-states define the “open” channel www.biorxiv.org/content/10.6...

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Alexis Rohou @alexisrohou.bsky.social · 12/08/2026

Come work with us at Genentech. We do drug discovery, pretty cutting edge cryoEM/ET stuff, and always learn a lot together. Any questions or recommendations, do let me know.

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Edward T Eng @edwardteng.bsky.social · 11/08/2026

Come by #IUCr2026 booth 33 to talk with representatives from the NIH sponsored #cryoEM & #cryoET service centers. cryoemcenters.org

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Edward T Eng @edwardteng.bsky.social · 20/07/2026

The next #CryoEM Current Practices Webinar speaker will be Jenn Cash from UCSD speaking on "Cryo-EM single-particle analysis of small and dynamic proteins" 7/30/2026 at 12 PM ET / 9AM PT Registration is at no-cost, but sign-up is required: us02web.zoom.us/webinar/regi...

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PlessLab @plesslab.bsky.social · 17/07/2026

Big thanks to Isabelle Baconguis (Vollum Institute) and her group for including us in their epic foray into the structural plasticity of ASICs, now out in Nature Structural and Molecular Biology: www.nature.com/articles/s41... 1/4

nature.com

Conformational plasticity of human acid-sensing ion channel 1a - Nature Structural & Molecular Biology

Using cryo-electron microscopy, Cahill, Hartfield et al. identified six structural states of human acid-sensing ion channel 1a, revealing how acidic conditions and peptide toxins regulate channel acti...

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Ben Barad @baradlab.com · 14/07/2026

Geopickr works perfectly with MorphometricsX - and is especially powerful with morphometrics preprocessing like extracting only high curvature regions or mitochondria-ER contact sites!

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Ben Barad @baradlab.com · 08/07/2026

My personal summer of code continues with another ChimeraX plugin - this time, MorphometricsX! Load quantified meshes from morphometrics (or pycurv) in ChimeraX with color-by-quantification and display alongside tomos and particles. Coming to the toolshed soon! #teamtomo github.com/baradlab/mor...

Screenshot of MorphometricsX rendering mitochondrial membrane surfaces in chimera with color-by-quantification.

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Reichow Lab @reichowlab.bsky.social · 08/07/2026

Thanks to the @structurabio.bsky.social team for highlighting our recent work 😍

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Ben Barad @baradlab.com · 27/06/2026

Just in time for the weekend, the 2nd beta for our Surface Morphometrics 2.0 release: github.com/GrotjahnLab/.... Beyond the major API change from the first beta (which used for the michigan class!), this one includes a major overhaul of the dual gaussian fitting for thickness and refinement.

github.com

Release 2.0.0b2 · GrotjahnLab/surface_morphometrics

A quality and robustness release on top of 2.0.0b1, focused on the density-profile bilayer fitting (mesh refinement and thickness measurement), a forgiving centralized config system, and packaging ...

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Edward T Eng @edwardteng.bsky.social · 25/06/2026

What if learning structural biology felt more like playing a game? Meowtabolism aims to make the structural sciences more interactive, accessible & fun. If you have educational applications let Muyuan (or me) know. store.steampowered.com/app/4045010/... #CryoEM #ScienceOutreach #STEMEducation

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Ben Barad @baradlab.com · 13/06/2026

I had such a fun time teaching at the U Michigan Cryo-ET Course this week! I taught quantitative ultrastructure analysis and we made cool figures like these! My course materials are at baradlab.com/michigan_tutorial for anyone to try. Workflow include mesh refinement and thickness measurement!

ChimeraX/ArtiaX visualization showing mitochondria-associated ribosomes connecting drives reduced IMM-OMM spacing in yeast.

Surforama depiction of mitochondrial outer membrane shows membrane-associated ribosomes.

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Alister Burt @alisterburt.bsky.social · 04/06/2026

“the best way to work with cryoET data is to engage with it directly, […] build familiarity with what is actually there. As tempting as it sometimes is to lean in to automation entirely, we cannot do visual proteomics by relying blindly on automation.” mgflast.github.io/easymode/use...

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Biohub @biohub.org · 04/06/2026

Better vitrification = better cryo-ET. We've opened an RFA for two-year grants to advance vitrification techniques for biological samples—welcoming applications from researchers in heat transfer, cryogenics, and materials science. Apply here: bit.ly/4uip6eJ

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Ben Cooper @bfcoop.bsky.social · 02/06/2026

I've just released a small open-source utility for RELION users: relion_tracker. RELION stores a lot of useful information in the *_optimiser.star files, but I often found myself repeatedly grepping STAR files to see how metrics were changing across iterations.

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Connor Garrels @garrels.bsky.social · 01/06/2026

Very excited about our new work highlighting the role of lipids in mediating multi-channel assemblies of Cx-46/50!

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Reichow Lab @reichowlab.bsky.social · 01/06/2026

Dual-channel Cx46/50 gap junction assemblies in a shared lipid-nanodisc = lipid-mediated packing and a lipid site near the NT gating region that is absent from single channels. Plus a 1.8 Å open-state single-channel benchmark! #cryo-EM 🍩’s #NIH-funded-research www.biorxiv.org/content/10.6...

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The bumbling biochemist (Bri Bibel) @bumblingbiochemist.bsky.social · 23/05/2026

Long shot, but, with lots of labs turning from crystallography to cryo-EM I’m wondering if anyone knows of labs potentially looking to offload some of their old crystallography supplies to a PUI with potential screening hits and really eager students but nothing to harvest with, etc.?

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Jonathan Pruneda @jnpruneda.bsky.social · 04/05/2026

Interested in microbiology, immunology, and host-pathogen interactions? Come work with us! Our department at OHSU is opening a search for a new tenure-track faculty position. See the job advertisement for details. Please share within your networks! www.nature.com/naturecareer...

nature.com

Faculty Position in Molecular Microbiology and Immunology - Portland, Oregon job with Oregon Health & Science University (OHSU) - Molecular Microbiology and Immunology | 12858852

The Department of Molecular Microbiology and Immunology at OHSU invites applications for a tenure-track Assistant or Associate Professor position.

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Jenna Norton @jenna-m-norton.bsky.social · 02/05/2026

This was fitting news to receive on May 1, international workers day. I will be returning to work on Monday after being kept on retaliatory administrative leave for 5 months and 3 weeks. I return along with the brave Katrina Declaration signers from FEMA, also reinstated this week. 🧵1/?

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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 02/05/2026

I love that portrait of you, Dr. Norton: weary but unyielding. You did not concede and your character speaks through your actions. We all know that you have acted at great cost. Thank you for your bravery and your dedication to our craft, and to the mission of the US National Institutes of Health.

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Edward T Eng @edwardteng.bsky.social · 01/05/2026

The 2027 Biophysical Society #CryoEM Subgroup welcomes nominations for the June Almeida Award for Mid/Senior-Career Women in CryoEM. The nomination deadline is November 13, 2026, but feel free to submit nominations anytime. Eligibility & requirements found here: www.biophysics.org/Awards-Fundi...

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Wyoming Wormboy @wyomingwormboy.bsky.social · 25/04/2026

Please repost! This comes from the good people at ChimeraX, who produce powerful up-to-date software to study protein (etc) structures, which are FREE to the community. 🙏 To stay viable and serve us, they need an experienced structural biologist to assume the leadership role on a funded project.

aprecruit.ucsf.edu

Faculty Position – In-Residence

University of California, San Francisco is hiring. Apply now!

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Edward T Eng @edwardteng.bsky.social · 16/04/2026

The next #CryoEM Current Practices Webinar speaker will be by Miao Zhang from University of Arizona speaking on "Structural basis for the pharmacological modulation of KCa2.2 channels" 4/30/2026 at 12 PM ET / 9AM PT Registration is at no-cost, but sign-up is required: us02web.zoom.us/webinar/regi...

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mansoor-steven.bsky.social @mansoor-steven.bsky.social · 09/04/2026

Excited to see this work out as a preprint! Proud to be part of this incredible international, multidisciplinary collaboration spanning structural biology, chemical biology, neuroscience, and translational medicine. This journey started ~7 years ago, and it’s been amazing!

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Oli Clarke @olibclarke.bsky.social · 20/03/2026

Great day at NYSBC, thanks for having me! 😊 If anyone wants to try out the tutorial, here it is: www.dropbox.com/scl/fi/054cm... There are linked videos for each step in the PDF, or I have also prepared the whole thing as a .PPT with embedded videos (2.7GB): www.dropbox.com/scl/fi/jnl9h...

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Alexis Rohou @alexisrohou.bsky.social · 24/02/2026

Our department at Genentech is hiring. We're looking for a freshly-minted PhD (0-3 years) protein biochemist / structural biologist to join as a Sr Scientist. A rare opportunity to join our group leader job family at a more junior level than we usually hire.

careers.gene.com

Senior Scientist, Protein Sciences in South San Francisco, California, United States of America | Research & Development at Genentech

Apply for Senior Scientist, Protein Sciences job with Genentech in South San Francisco, California, United States of America. Research & Development at Genentech

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Verena Resch | 🧪🖥️ @verenaresch.bsky.social · 19/02/2026

🧪Help needed! I am currently gathering ideas for a new and updated Blender course tailored for chemists. Besides importing molecules into Blender, what topics or features would interest you the most? Any input is highly appreciated 😊

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Edward T Eng @edwardteng.bsky.social · 20/02/2026

The next #CryoEM Current Practices Webinar speaker is Vladimir Kolyadko from Children’s Hospital of Philadelphia speaking on "Cryo-EM of Liposome-Assembled Macromolecular Complexes to Reveal Protein-Membrane Interactions in Hemostasis" 2/26/2026 at 12PM ET / 9AM PT us02web.zoom.us/webinar/regi...

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Dimitry Tegunov @dtegunov.bsky.social · 16/02/2026

I had Claude make this as a mini-game for Relay's disconnect screen (like Chrome's dinosaur), but then pivoted to stand-alone. In this game, you have to find Euler angles matching the target projection, i.e. cosplay RELION. It can be pretty hard. Works on mobile too! warpem.github.io/euler-hunt/

warpem.github.io

Euler Hunt

Can you find the Euler angles of a cryo-EM projection?

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U-M Life Sciences Institute @umlifesciences.bsky.social · 09/02/2026

Join us this summer for U-M's 2026 #CryoET Data Processing Workshop! This four-day workshop will introduce participants to standard image processing packages and all aspects of cryo-ET data processing. Apply by March 20: myumi.ch/lsi-cryo-workshop-2026 @jbquerido.bsky.social @shyamalm.bsky.social

Cryo-electron tomogram on a navy background with text: Cryo-ET Data Processing Workshop. June 7-11, 2026

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Edward T Eng @edwardteng.bsky.social · 05/02/2026

Looking forward to #BPS2026 in San Francisco? Come by the NIH sponsored Transformative High-Resolution Cryo-Electron Microscopy National Centers for #CryoEM at booth 410. Our mission is to broaden access to high-resolution cryo-electron microscopy and tomography technologies - cryoemcenters.org

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Ben Barad @baradlab.com · 04/02/2026

I've been working on Surface Morphometrics for a new version (coming soon), and made some significant (AI-assisted) performance improvements, especially in pycurv (20-50x!). If you've had technical issues or just felt like it was too slow, give it another try! #teamtomo github.com/GrotjahnLab/...

github.com

GitHub - GrotjahnLab/surface_morphometrics: Morphometrics for Membrane Surfaces Segmented from Cryo-ET or other volumetric imaging.

Morphometrics for Membrane Surfaces Segmented from Cryo-ET or other volumetric imaging. - GrotjahnLab/surface_morphometrics

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Danielle Grotjahn @nanigrotjahn.bsky.social · 01/02/2026

Are you a cell biologist who secretly thinks cellular cryo-electron tomography is just George Palade-era EM, but fancier? Join this webinar to see how modern #teamtomo has shifted from pretty pictures to quantitative, local membrane biology, and how that changes the questions we can ask.

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Jeff Rueter @jeffrueter.bsky.social · 25/01/2026

Kare 11 local news just read, in full, this statement from Michael and Susan Pretti, the parents of Alex Pretti. "Please get the truth out about our son."

Statement from Michael and Susan Pretti
Parents of Alex Jeffrey Pretti

“We are heartbroken but also very angry.

Alex was a kindhearted soul who cared deeply for his family and friends and also the American veterans whom he cared for as an ICU nurse at the Minneapolis VA hospital. Alex wanted to make a difference in this world. Unfortunately, he will not be with us to see his impact.

I do not throw around the ‘hero’ term lightly. However, his last thought and act was to protect a woman. The sickening lies told about our son by the administration are reprehensible and disgusting. Alex is clearly not holding a gun when attacked by Trump’s murdering and cowardly ICE thugs. He had his phone in his right hand and his empty left hand is raised above his head while trying to protect the woman ICE just pushed down, all while being pepper sprayed.

Please get the truth out about our son. He was a good man. Thank you.

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Will Stancil @whstancil.bsky.social · 24/01/2026

in case you're curious about how angry Minnesota is about ICE, it was -20 today

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