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Pauline Franz

@paulinefranz.bsky.social
1.3K followers 758 following 9 posts

Chemical Biologist in 🇬🇧 ¦ passionate about illustrating science 🐡 #proteinchemistry

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Reposted by Pauline Franz
Matteo Doudin @matteodoudin.bsky.social · 04/04/2025
I am very happy to share that I was awarded a PhD fellowship from the Boehringer Ingelheim Fonds (BIF) for my project about nucleosome depletion in @lcbm-epfl.bsky.social with @beatfierz.bsky.social. Looking forward to joining the BIF community 😊🥳
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Carlos Moreno-Yruela @carlosmyruela.bsky.social · 04/02/2025
#SIRT7 is a histone deacetylase with highly specific activity on #chromatin substrates. We just published mechanism-based #cryoEM structures of #SIRT7 on nucleosomes to understand its activity 👇 www.nature.com/articles/s41... (1/8) #ChemBio #ChemSky
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Rob Schneider @robertife.bsky.social · 08/12/2024
Please RS/RT. #GordonConference on "Histone and DNA Modifications" #epigenetics #chromatin 20-25. July 2025. Il Ciocco, Italy. Great speaker lineup. ➡️Register now www.grc.org/histone-and-...
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Tim Triche, Jr.🔰 @timtriche.bsky.social · 19/12/2024
Dear world: this is what a graphical abstract is supposed to look like.
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Pauline Franz @paulinefranz.bsky.social · 19/12/2024
What a great conclusion to my final days at EPFL: our 🔥article is highlighted on the @angewandtechemie.bsky.social Frontispiece!! ▶️ tinyurl.com/mvtecrsz @beatfierz.bsky.social #chemicalbiology #clickchemistry #DNArepair #SciArt🐡 🧪
Frontispiece of Angewandte Chemie Int. Ed. showing a pop-art style drawing of protein structures and a hand symbolizing the protein RNF168.
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Angewandte Chemie @angewandtechemie.bsky.social · 10/12/2024
Hi there: we're happy to be on BlueSky now, too! Stay tuned as we're getting set up here for the #ChemSky community - more to follow soon!
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Nina Hartrampf @ninahartrampf.bsky.social · 04/12/2024
🥳 Today we celebrated the PhD defense of our very first PhD student Kevin Schiefelbein 🤩 Kevin told us about his Lasso Peptide journey over the past four years, and it was so great to see the full story coming together. Congratulations Kevin, and thank you for everything! #proudPI
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Altmetric @altmetric.com · 02/12/2024
Four panel meme based on the worst Star Wars film. Altmetric is tracking Myspace.
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Life Sciences Switzerland (LS2) @lifesciswitzerland.bsky.social · 27/11/2024
We want to thank everyone for joining and to congratulate the winners! A big thank you to all sponsors supporting this meeting! We hope to see you all next time. #LS2 #ICMT #Biophysics #LifeScience #Switzerland #Conference #Science
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Micha Rapé Lab @micharapelab.bsky.social · 03/12/2024
Very excited to present the structural and mechanistic basis for stress response silencing by the monster E3 ligase SIFI. www.biorxiv.org/content/10.1...
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Micah G. Allen @micahgallen.com · 02/12/2024
Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know!
A screenshot of a paper on bioarxiv illustrating the lack of blue sky share button!
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Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · 25/11/2024
Look who's here @pnas.org ✔️ @science.org ✔️ @naturecellbiology.bsky.social ✔️ @natrevgenet.bsky.social ✔️ @naturebiotech.bsky.social ✔️ @naturemicrobiol.bsky.social ✔️ @naturechemistry.bsky.social ✔️ @genesdev.bsky.social ✔️ @cellchembiol.bsky.social ✔️ @genomeresearch.bsky.social ✔️ @jcellbiol.bsky.social ✔️
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Simon Rössler @simonrossler.bsky.social · 25/11/2024
MIT researchers in collaboration with Novo Nordisk report in Nature an alternative to injections for the delivery of biologic drugs. This needle-free method leverages an ingestible capsule inspired by squids that releases drugs directly into the digestive tract wall. www.nature.com/articles/s41...
nature.com
Cephalopod-inspired jetting devices for gastrointestinal drug delivery - Nature
Tethered or ingestible delivery systems that deliver liquid microjets in axial and radial directions can be used to deliver macromolecules to different parts of the gastrointestinal tract with good bi...
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Waser Group @lcsolab.bsky.social · 23/11/2024
On November 20, the new class of peptide-cyanobenzene dye photocatalysts developed by Xingyu have been first made public in a preprint at ChemRxiv, including a great collaboration Wei Cai in the @beatfierz.bsky.social group and Dr. Anne Sophie Chauvin chemrxiv.org/engage/chemr...
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Spirochrome @spirochrome.com · 22/11/2024
Celebrating #FluorescenceFriday and hopefully brightening your timeline with these live intestinal #organoids stained with our actin probe SPY555-FastAct.
SPY555-FastAct stained intestinal organoids growing in in microwells. the image is a composite of a brightfield image (grey) and SPY555-FastAct (cyan).
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Rita Strack @ritastrack.bsky.social · 19/11/2024
This the (short, funny, sad) video we got to see on imaging women's brains at the CZI Imaging meeting as part of Nina Miolane's talk. Worth a few minutes and worth a share. www.youtube.com/watch?v=tX5u...
youtube.com
"What if...?"
YouTube video by Ann S. Bowers WBHI
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Alexis Rohou @alexisrohou.bsky.social · 18/11/2024
🚨 Attention #teamtomo PhD students! 🚨 12-week paid internship opportunity at Genentech. Want to see how we use cryoET in pharma? And spend the summer 2025 in the Bay Area? Details and application link here: roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
roche.wd3.myworkdayjobs.com
2025 Summer Intern - Department of Structural Biology
Department Summary The CryoEM Group in the Department of Structural Biology is dedicated to providing high-resolution structural insights into biological macromolecules involved in health and disease....
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Altmetric @altmetric.com · 18/11/2024
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics
docs.bsky.app
Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
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Thorn-Seshold Lab @thornsesholdlab.bsky.social · 17/11/2024
📯📯 Chemical Biology starter pack 📯📯 140 PIs & groups posting primary research in chemical biology. Please reskeet (?) & reply to this post if you want to be added! go.bsky.app/KLrTWoj Let's make ChemBioSky even greater again! #realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange
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Razvan Borza @rborza.bsky.social · 17/11/2024
⚠️THREAD OF ALL SCIENCE-RELATED STARTER PACKS! ⚠️ 🔄Share to help people finding its topic/field - STRUCTURAL BIOLOGY Structural Biology 1: bsky.app/starter-pack... Structural Biology 2: bsky.app/starter-pack... Crystallography: bsky.app/starter-pack... Synchrotron&CryoEM: bsky.app/starter-pack...
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Rune Busk Damgaard @rbdamgaard.bsky.social · 15/11/2024
Check out this list of ubiquitin and Ubl profiles to follow. Repost if you want me to add you to it. Let’s create a good community here ☁️ go.bsky.app/3VPQofn
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Dorien Pastoors @dpastoors.bsky.social · 14/11/2024
I am really enjoying the surge of people to bluesky but still kind of missing the VERY early career group of people! (Aging in academia is a funny thing) - I went ahead and made this starter pack go.bsky.app/Jq8YaQM - if you would like to be removed/added please let me know
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Chemistry World @chemistryworld.com · 28/10/2024
More than 9000 studies published in open-access journals contain figures created using the commercial scientific illustration service BioRender, which should technically mean that they are available for free reuse. But that doesn’t appear to be the case. www.chemistryworld.com/news/thousan...
chemistryworld.com
Thousands of published studies may contain images with incorrect copyright licences
Questions raised over copyright licence that covers images created using scientific illustration service Biorender
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Luc Reym⌬nd @lreymond.bsky.social · 13/11/2024
Here is a starter pack dedicated to fluorescent probes, sensors and fluorophores makers. I'm sure it's incomplete, please reply to this post to be added or suggest someone. go.bsky.app/MtgJE4w
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Stephan Hacker @stephanhacker2.bsky.social · 13/11/2024
Great to see so many new people from the scientific community joining here. Welcome! I would be very happy to connect with everyone on topics such as #Science, #Chemistry, #Chemsky, #ChemicalBiology, #Antibiotics, #CovalentInhibitors, #ChemicalProteomics, #ABPP and general topics of #academia.
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Lazare Saladin @lazaresaladin.bsky.social · 12/11/2024
Happy to see our latest work in ChemEurJ🎉. Here we present a new way to get a photoactivatable BODIPY for cell imaging. This probe allows super-resolutive images in the green channel. Special thanks to Valentine, Maxence, Pascal and Mayeul. chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
chemistry-europe.onlinelibrary.wiley.com
Targeted Photoactivatable Green‐Emitting BODIPY Based on Directed Photooxidation‐Induced Activation and its Application to Live Dynamic Super‐Resolution Microscopy
PFB is an efficient, green-emitting, photoactivatable probe based on BODIPY. Upon irradiation with visible light (488 nm), directed photooxidation oxidizes the furanyl group and eliminates the quench....
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Pauline Franz @paulinefranz.bsky.social · 02/04/2024
How to practice your #storytelling in #science? Originating from a workshop by @mirkobischofberger.bsky.social, Julius, Dani, and I started to develop the learning tool and game #SciCubes. Help us bring this project to life by ordering your set of🎲 here 👉 wemakeit.com/projects/sci... THANK YOU!
Image shows three dice with different scientific motives on a black surface and the SciCubes logo placed below.
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Pauline Franz @paulinefranz.bsky.social · 21/01/2024
Spreading chemistry 🧪 into biology 🌱 has been one of my primary motivators to start a PhD! I'm excited to share our review on how #chemicalbiology approaches have empowered the study of chromatin ubiquitylation! Here's the link to our #OpenAccess review doi.org/10.1016/j.jm...
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Carlos Moreno-Yruela @carlosmyruela.bsky.social · 10/01/2024
Histone deacylases (#HDACs and #sirtuins) have specific and quite different ways of finding their targets through #chromatin 🧬. Why do we know this, and what are we doing to study it in detail? All the info in our new review with @beatfierz.bsky.social! 👇🏻 portlandpress.com/biochemsoctr...
portlandpress.com
Revealing chromatin-specific functions of histone deacylases
Histone deacylases are erasers of Nε-acyl-lysine post-translational modifications and have been targeted for decades for the treatment of cancer, neurodegeneration and other disorders. Due to their r...
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Beat Fierz @beatfierz.bsky.social · 09/01/2024
Check out the new review from @carlosmyruela.bsky.social on the using synthetic chromatin to investigate the function of histone deacylases! doi.org/10.1042/BST2...
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Beat Fierz @beatfierz.bsky.social · 16/12/2023
Impressions from the LCBM Xmas party.!Happy holidays!!! 🎄🎁🎅🏽
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