Reposted by Micha Sam Brickman RaredonKarl Deisseroth @deisseroth.bsky.social · 05/10/2026Thank you to everyone sharing in this moment! I’m so grateful to all my trainees & collaborators… dlab.stanford.edu/group-members (pic: Peter and I together in 2017) Reading for all those asking: for technical details: dlab.stanford.edu for everyone: deisseroth.org/projections 491373285
Micha Sam Brickman Raredon @msbr89.bsky.social · 23hHow did Rosalind Franklin miss the helix in her iconic DNA image? She didn’t | Science | AAAS www.science.org/content/arti...science.orgHow did Rosalind Franklin miss the helix in her iconic DNA image? She didn’tNew analysis refutes James Watson’s claim he was first to recognize significance of famed photograph 51 021
Reposted by Micha Sam Brickman RaredonScience Magazine @science.org · 05/10/2026Exclusive: A new analysis refutes James Watson’s claim that he was the first to recognize the significance of the famed photograph 51. scim.ag/4rTKck8scim.agHow did Rosalind Franklin miss the helix in her iconic DNA image? She didn’tNew analysis refutes James Watson’s claim he was first to recognize significance of famed photograph 51 412045725
Reposted by Micha Sam Brickman RaredonDagmar Iber & CoBi @iberd.bsky.social · 05/10/2026Celebrating another cover by @maltemederacke.bsky.social Directed cell migration is a versatile mechanism for rapid developmental pattern formation www.cell.com/newton/fullt... 183
Reposted by Micha Sam Brickman RaredonMichael Riedl @mriedl.bsky.social · 05/10/2026What could you learn about a collective system if you could resolve all of its energetic pathways? We track energy flow as active spheres transition from disordered motion to collective order. And the energetic state changes just as their motion. arxiv.org/abs/2609.31059 1123
Reposted by Micha Sam Brickman RaredonEpigenome Technologies @epigenometech.bsky.social · 02/10/2026Epigenetics News - Old hearts age backwards: transplanted organs adjust to host's biological age www.nature.com/articles/d41... #Epigenetics #News #Aging #Transplant --- Cancer, immunology, and aging; epigenometech.comnature.comOld hearts age backwards: transplanted organs adjust to host’s biological ageTracking the biological age of grafted organs suggests that donor pools could be expanded to boost organ availability. 054
Reposted by Micha Sam Brickman RaredonSchallek Lab @schalleklab.bsky.social · 02/10/2026#FluorescenceFriday Pericytes are tiny cells that surround microvessels. Here we show how single cells wrap their "tentacles" around retinal capillaries 👁️ Color: renders depth bit.ly/3TFifQe @flaumeye.bsky.social @cvsuor.bsky.social @urneuroscience.bsky.social @urochester.bsky.social 1275
Reposted by Micha Sam Brickman RaredonBerna Devezer @devezer.bsky.social · 02/10/2026A revised version of this preprint is now posted on arXiv. The theory section is rewritten, improving model exposition based on feedback we received, we fixed some confusion and errors, contextualized the models more carefully so the interpretation becomes clearer, and improved the overall writing.arxiv.orgThe Difference Between "Replicable" and "Not Replicable" Is Not Itself Scientifically ReplicableReplication studies estimate the replicability rate of scientific results by aggregating binary verdicts of experiments as ``replicated'' and ``not replicated''. These estimates assume rarely attainab... 68418
Reposted by Micha Sam Brickman RaredonArjuna Rajakumar PhD @arjunarajakumar.bsky.social · 19/09/2026So proud of my lab mate @sagrill.bsky.social (whose on the job market 👀) for this magnum opus from @remlehmann.bsky.social lab @whiteheadinstitute.bsky.social ScRNA-seq of 🪰 germ cells reveals new biology, answers age old questions, and proposes new paradigms! 1/8 www.biorxiv.org/content/10.6... 35928
Reposted by Micha Sam Brickman RaredonPaul Byrne @theplanetaryguy.com · 02/10/2026This will never stop blowing my mind. A 12-year sequence of real telescope images of a star 133 lightyears away. And around it, four planets slowly orbiting. Four real exoplanets, each more massive than Jupiter, imaged as they move around their host star. 282185623
Reposted by Micha Sam Brickman RaredonDale Moulding @dalemoulding.bsky.social · 01/10/2026Having seen the news: www.bbc.co.uk/news/article... thought I'd share a cilia movie captured at UCL GOS ICH with Eriomina Shahaj & Vanesa Papastavrou using simple DIC on a Nikon Ti2 with DIC at 60x1.4. 500 fps here slowed down 20 times. Processed with Nikon's denoiseAI and an unsharp mask in Fiji. 88622
Reposted by Micha Sam Brickman RaredonErik van Nimwegen @erikvannimwegen.bsky.social · 01/10/2026Hey, I heard about Bonsai, but now I heard there is another method called MILK that also visualizes scRNA-seq on trees. And it is much faster! Should I just use that then? A tree is a tree, right? TLDR: No. #methodsmatter Not even close. On realistic synthetic data MILK performs worse than UMAP. 1148
Reposted by Micha Sam Brickman RaredonNSF–DOE Rubin Observatory @rubinobservatory.org · 01/10/2026"Let's just take a closer look." Famous last words. NSF–DOE Rubin Observatory images reveal stars, galaxy clusters, nebulae, and a mindblowing number of distant galaxies hiding in the background. 🔭🧪 So go ahead. Zoom in. You might want to clear your schedule. ➡️ skyviewer.app 16618
Reposted by Micha Sam Brickman RaredonBenjamin @benjaminschneider.ch · 30/09/2026Werner Herzog will be the last human being whose next word no language model can predict 9567144
Reposted by Micha Sam Brickman RaredonEric Topol @erictopol.bsky.social · 30/09/2026Why do our cells age? It's not just wear and tear, accumulated damage. Loss of cell identity takes center stage. A new Nature paper and connection with prior work that substantially advances the science of aging. In the new Ground Truths. erictopol.substack.com/p/loss-of-ce...erictopol.substack.comLoss of Cell Identity Drives Human AgingThat’s What Biological (Epigenetic) Aging Clocks Are Measuring 817551
Reposted by Micha Sam Brickman RaredonAlejandro Brenes @ajbrenes.com · 30/09/2026I've used it to re analyse my neutrophil single cell proteomics data. The representation was excellent and made much biological sense. Mature neutrophils sit close together. Immature branch off. NETing populations are far off. Its great ill keep using Bonsai! Great tool! 193
Reposted by Micha Sam Brickman Raredonmyosinactncrazy.bsky.social @myosinactncrazy.bsky.social · 30/09/2026www.biorxiv.org/content/10.6...biorxiv.orgSelf-centering steady-state flows emerge in confined actomyosin networksThe actin cytoskeleton drives shape changes and transport in cells and supports mechanical signal transmission. However, how cells control and use active cytoskeletal flows at the mesoscale is not wel... 033
Reposted by Micha Sam Brickman RaredonAlfonso Martinez Arias @amartinezarias.bsky.social · 29/09/2026Intriguing set of observations on how ‘dual-aggregate gastruloids’ lead to the emergence of foregut-pharyngeal mesoderm co-development and patterning www.biorxiv.org/content/10.6... #gastruloids #MustRead 2125
Micha Sam Brickman Raredon @msbr89.bsky.social · 30/09/2026Now see this is a contender for Nikon Small World. Beautiful!! 110
Reposted by Micha Sam Brickman RaredonKamryn Gerner-Mauro, PhD @kamryngerner.bsky.social · 30/09/2026Fusion of E14 chicken parabronchi! Green staining with DSHB 7D6 for L-CAM/E-cadherin stains the lung epithelium. Magenta stains for smooth muscle actin that constricts the developing parabronchi. This was imaged on a confocal microscope and is an MIP. #ShowYourWork #SeenWithDSHB #Figure1 2173
Reposted by Micha Sam Brickman RaredonbioRxiv Bioinfo @biorxiv-bioinfo.bsky.social · 29/09/2026Cell-Hub Database: a consolidated multi-species ligand-receptor interaction resource for cell-cell communication analysis www.biorxiv.org/content/10.64898/20… 021
Reposted by Micha Sam Brickman RaredonpreLights @prelights.bsky.social · 29/09/2026Two #preprints detail new & complementary ways to match mechanical readouts from tissues to OMICs. #preLight by @fadelvalle.bsky.social - includes a discussion with the author teams @lindithium.bsky.social @huanting-ong.bsky.social @jennyoung.bsky.social ⬇️ prelights.biologists.com/highlights/m...prelights.biologists.comMechanoMaST – a multimodal pipeline for spatially registering mechanical and transcriptomic tissue data; Paired-surface spatial mechanomics links tissue stiffness maps to spatial transcriptomics - pre...Separated by only a few hours! These two novel preprints detail new and complementary ways to match mechanical readouts from tissues to OMICs 041
Reposted by Micha Sam Brickman RaredonMiriam Quick @miriamquick.bsky.social · 29/09/2026Love this 021
Reposted by Micha Sam Brickman Raredonfeeb | yuritober!! @magicmooshka.bsky.social · 09/01/2026it’s come to my attention that my tumblr post has been crossposted to bluesky, so I’m posting it on my account here #AntiAI #GenAI 113136236617
Reposted by Micha Sam Brickman RaredonThe Plant Journal @theplantjournal.bsky.social · 27/09/2026𝐍𝐞𝐰 𝐬𝐩𝐞𝐜𝐢𝐚𝐥 𝐢𝐬𝐬𝐮𝐞 𝐑𝐄𝐂𝐄𝐏𝐓𝐎𝐑-𝐋𝐈𝐆𝐀𝐍𝐃 𝐈𝐍𝐓𝐄𝐑𝐀𝐂𝐓𝐈𝐎𝐍𝐒 🌱 Edited by @adsteinbrenner.bsky.social @veroglez.bsky.social @isabelmonte.bsky.social @elwirasmakowska.bsky.social 📖 Read the Editorial 👉 doi.org/10.1111/tpj.71135 🔎 Explore the complete Special Issue 👉 onlinelibrary.wiley.com/doi/toc/10.1...doi.orgUnderstanding and engineering receptor–ligand interactionsClick on the article title to read more. 096
Reposted by Micha Sam Brickman RaredonSaez-Rodriguez Group @saezlab.bsky.social · 29/09/2026Happy to see the peer-reviewed version of SpaCEy now out: 📄 Published paper: www.nature.com/articles/s41... 💻 Code: github.com/saezlab/SpaCEy 1147
Reposted by Micha Sam Brickman Raredonc0nc0rdance @c0nc0rdance.bsky.social · 27/09/2026I'll save you the click-through: A lab at University of Copenhagen had been feeding draft manuscripts & data into "Claude Science" & then Anthropic announces a discovery that this lab made a year ago but hasn't published yet. It's plausible that Claude found the same signatures independently... 7268118
Reposted by Micha Sam Brickman Raredonsamuel mehr @mehr.nz · 27/09/2026another day, another bit of evidence that the scientists who willingly hand over proprietary information to AI firms may experience some consequences 7271120
Reposted by Micha Sam Brickman RaredonOs Keyes @okeyes.bsky.social · 15/09/2026Since we’re doing another round of “AI will destroy humanity” doom-hype, it’s a good time to announce a new paper myself and my postdoc advisor just had accepted by BioSocieties on just this. TL;DR: almost all the “AI can make bioweapons” literature comes ultimately from the Effective Altruists.ironholds.org 17749272
Reposted by Micha Sam Brickman RaredonMark A. Hanson @hansonmark.bsky.social · 26/09/2026The solution isn't obvious. The end game is to adhere to DORA, CoARA, etc... But the committees making hiring decisions are mostly treading water to understand the papers' basic premise and rarely expert enough to critique it robustly. We need to play 4D chess here: publish with non-profits. 4/n 1103
Reposted by Micha Sam Brickman RaredonMark A. Hanson @hansonmark.bsky.social · 26/09/2026The strain on peer review is due to our obsession of submitting *everything* to a journal and requiring PRE-PUBLICATION peer review of it before it's deemed "mature science." The problem with peer review is that no one can accept we have to stop pre-publication reviewing as default. 2/n 263
Reposted by Micha Sam Brickman RaredonMark A. Hanson @hansonmark.bsky.social · 26/09/2026I'm surprised a community of publishing writers can blame AI for the problems of peer review when those same writers cite our study, "the strain on scientific publishing", which characterizes how this problem existed before AI. bit.ly/StrainQSS It's the incentives structure, not the AI. 1/nscholarlykitchen.sspnet.orgAsk the Chefs: Peer Review Capacity — Uncomfortable Truths and Overlooked Conversations - The Scholarly KitchenFor Peer Review Week 2026, we asked the Chefs two questions: What is one uncomfortable truth about peer review that the scholarly publishing community doesn’t talk about enough? And, beyond recruiting... 32515
Reposted by Micha Sam Brickman RaredonHao Yin @haoyin.bsky.social · 25/09/2026Cilia - AI champion show🏆 Credit: GPT6-Astra Inspired by @christlet.bsky.social 28420
Reposted by Micha Sam Brickman RaredonA/Prof Sam Stehbens PhD (She/Her) @samstehbens.bsky.social · 26/09/2026#Nikon will address our concerns by next week. Hopefully the pre-processed movie & raw data will be part of that. #NikonSmallWorld 3268
Reposted by Micha Sam Brickman RaredonVenkat Rao @venkyrao.bsky.social · 26/09/2026Jumping on the bandwagon with a 3D view of Xenopus multiciliated cells: cilia (magenta) sprouting above the apical actin network (cyan) 🐸. Not live, but no #AISLOP 15713
Reposted by Micha Sam Brickman RaredonMatt Henderson @matthen.com · 26/09/2026How have the constellations changed since humans first looked up? Has the big dipper always pointed to Polaris? Has Polaris always been the North star? (nope!) 211119
Reposted by Micha Sam Brickman RaredonIgor Adameyko @adameykolab.bsky.social · 25/09/2026Research Briefings about our paper in Nature Genetics (atlas of human facial development): www.nature.com/articles/s41....nature.comHuman facial development atlas illuminates enhancer-based control of facial individuality - Nature GeneticsThe facial skeleton is essential for eating, breathing, kissing, speech and personal identity. Our spatiotemporally resolved cell atlas of human embryonic craniofacial development will facilitate a de... 1219
Reposted by Micha Sam Brickman Raredonepithelial mechanics fan club @epimechfc.bsky.social · 24/09/2026Ramos, R., Swedlund, B., Ganesan, A. K., Morsut, L., Maini, P. K., Monuki, E. S., ..., Chuong, C.-M., & Plikus, M. V. (2024). Parsing patterns: Emerging roles of tissue self-organization in health and disease. Cell, 187(13), 3165–3186. #EpithelialMechanicsReview doi.org/10.1016/j.ce... 082
Reposted by Micha Sam Brickman RaredonChristophe 🔬 Leterrier @christlet.bsky.social · 25/09/2026The Small World in Motion winner is now officially a "rendition" 🙄 7548
Reposted by Micha Sam Brickman RaredonJohn Stott @jpsastro.bsky.social · 24/09/2026Had a UKRI funded grant proposal rejected at the "AI triage stage". "This AI-based triage was used only to identify approximately 50% of the strongest proposals to take forward to full human review." 🧪 #academicsky 40434239
Reposted by Micha Sam Brickman RaredonMwahahahahahadScientist @mads100tist.bsky.social · 25/09/2026This is it. This is what everyone is enabling by humoring genAI: you spend months writing something that took you years to get at, for an opaque algorithm that a few control to spit a number and cut you off right there and then. This is what we're up against 🧪 14410171
Reposted by Micha Sam Brickman RaredonTobias Maier @weitergen.de · 25/09/2026In der Familie zusammen essen ist gesünder als alleine zu essen. www.science.org/doi/10.1126/... Das Paper hat den gesundheitlichen Benefit sozialer Interaktionen messbar gemacht.science.orgSocial Physiology: Human homeostasis is more efficient in social proximityPhysiological homeostasis is traditionally viewed as an individual process optimized through evolution to minimize the energetic costs of regulation. However, it remains unknown whether social proximi... 043
Reposted by Micha Sam Brickman RaredonLennart Hilbert @lennarthilbert.bsky.social · 24/09/2026I hate when this happens. And, let me tell you, it happens. It’s a really bad look … omitting prior, highly relevant work is academically inappropriate, especially if it was brought to one’s attention directly. It violates commonly applicable standards and proper process. 063
Reposted by Micha Sam Brickman RaredonAriel M. (she/her) @byarielm.fyi · 24/09/2026Working on getting better feeds so people can post these things and actually get seen! Here's some a few: PhD Chatter Science For You Math & Comp Bio They're still in development / testing but I saw this in Science For You feed ☺️blacksky.communityScience For You by @byarielm.fyiComing soon TM 021
Reposted by Micha Sam Brickman RaredonChristophe 🔬 Leterrier @christlet.bsky.social · 24/09/2026I think I'm going to lose it being lectured on microscopy image presentation integrity by the winner of the Small Artificial World in Motion competition 1417833
Reposted by Micha Sam Brickman RaredonSimon Cleary @simoncleary.bsky.social · 23/09/2026Why would a company that sells high-end cameras and microscopes want to give the impression that we could just use computers to dream up pretty pictures for us? 042
Reposted by Micha Sam Brickman RaredonAnh Hoang Le, PhD 🏳️🌈🏴🇻🇳 @anhhle2702.bsky.social · 23/09/2026The general public media now uses this video as their go to when it comes to ciliated cells. The impact is beyond this competition! 2123
Reposted by Micha Sam Brickman RaredonChristophe 🔬 Leterrier @christlet.bsky.social · 23/09/2026As they are not active here, I left a comment on the LinkedIn post from Nikon Small World about the concerns I think I share with many (first screenshot is their post, second screenshot is my comment) lnkd.in/p/ecdT6saZ 78917