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Marlies Oomen

@marliesoomen.bsky.social
295 followers 278 following 32 posts

Studying regulation of and by TEs in mammalian genomes. Assistant Professor at MCCB @UMassChan. www.oomenlab.com

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Reposted by Marlies Oomen
Çağrı Çevrim @cagricevrim.bsky.social · 01/10/2026
Your favorite website for illustrations of almost all organisms is looking for donations to help cover its running costs! Please consider donating to help keep this open-source platform running: www.phylopic.org/images
phylopic.org
All Silhouette Images on PhyloPic
Browse all the free silhouette images in PhyloPic.
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Sonya Widen @sonyawiden.bsky.social · 30/09/2026
I will absolutely be taking this energy into the culture of my own lab. "I don't know" isn't a bad or scary sentence, and being comfortable saying it out loud is a huge green flag at all levels of academia.
science.org
I thought ‘I don’t know’ signaled scientific incompetence. Now, I know different
When this researcher started a postdoc, he felt he was expected to present himself as knowledgeable
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Matthew Freeman @mjafreeman.bsky.social · 30/09/2026
Yet another opportunity @dunnschool.bsky.social! We are looking for an Associate Professor If you have exciting research plans, @dunnschool.bsky.social is a great place: excellent science (and lovely people, obvs) www.path.ox.ac.uk/vacancy/asso...
path.ox.ac.uk
Associate Professorship of Cancer Biology - Sir William Dunn School of Pathology in association with the Queen’s College. - Dunn School
We are seeking to appoint an Associate Professor working in the area of the cellular and/or molecular biology of cancer, to be based in Oxford University’s Sir William Dunn School of Pathology. The ro...
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Juan Fuxman Bass @fuxmanlab.bsky.social · 27/09/2026
Although hundreds of viral transcriptional regulators (vTRs) have been identified, we know little about the host pathways they rewire to promote replication and persistence or their mechanisms of action. In our new paper, we addressed this gap across human viruses. 🧵 www.nature.com/articles/s41...
nature.com
Functional characterization of viral transcriptional regulators reveals extensive rewiring of host pathways - Nature Communications
The authors here show how viral transcriptional regulators reprogram human gene activity through diverse mechanisms, revealing shared strategies used by different viruses to control host pathways and ...
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Giulia Paci @giuliapaci.bsky.social · 25/09/2026
Last month to apply for ECR places on our workshop on developmental robustness taking place next April. Apply and spread the word, I promise it’s going to be great!
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Cedric Feschotte @cedricfeschotte.bsky.social · 24/09/2026
Thrilled to see this published today! Truly special because we made the initial discovery >15 yrs ago! We found two copies of a human gene called BC200 embedded in a human poxvirus. BC200 blurs the line between gene & transposon—both functional & mutagenic! www.science.org/doi/10.1126/... 🧵1/n
science.org
Escape of the BC200 gene to a human poxvirus reveals its persistent transposition in primates
Transposable elements mobilize within and occasionally between genomes, including from host to virus. We identified two insertions of the human BC200 noncoding RNA gene in the poxvirus molluscum conta...
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Quanta Magazine @quantamagazine.org · 23/09/2026
“Jumping genes” can cut and paste themselves into new locations in the genome. But they’re more than parasites or genetic junk. www.quantamagazine.org/how-virus-li…
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Maya Voichek @mayavoichek.bsky.social · 24/09/2026
Super excited to share my postdoctoral work at @imbavienna.bsky.social @viennabiocenter.bsky.social - We discovered that some retrotransposons, or "jumping genes" 🧬, are able to spread from cell to cell via a new viral infectivity route. A short thread: 🧵👇 (1/7)
AI-generated illustration of the soma-to-germline transmission of retrotransposons described in our work
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Nezar Abdennur @nvictus.bsky.social · 19/09/2026
The 4DN Center for 3D Structure and Physics of the Genome proudly presents: "Stepwise reorganization of chromosome conformation and nuclear organization during stem cell differentiation". www.biorxiv.org/content/10.6...
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Development @dev-journal.bsky.social · 21/09/2026
At Development, we #LovePostdocs. For #NPAW2026, we highlight our 2026 cohort of Pathway to Independence fellows. Read about their unique journeys as they work to secure independent positions, their excitement about the latest advances in their fields & the advice they have received along the way.
journals.biologists.com
Dev | PI fellows 2026 | Development | The Company of Biologists
Dev | PI fellows 2026 | Development | The Company of Biologists .card-list-container { margin-top: 2em; } .card-list-container h2 { margin-bottom: 1em; } .ca...
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Kazuhiro Maeshima @kazu-maeshima.bsky.social · 08/09/2026
Is euchromatin really “open”? 🧬 Using super-resolution imaging🔬 our new study @natgenet.nature.com reveals: Euchromatin forms condensed domains in live cells. Cohesin constrains them and prevents domain mixing for proper transcriptional insulation🚧 🔗 www.nature.com/articles/s41... (1/2)
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Max Farnworth @maxfarnworth.bsky.social · 08/09/2026
Reminder I am hiring a postdoc and PhD student. Thanks to all the applications I already received 🙏 If you know anyone particularly with single cell expertise for the postdoc position, please let me know!
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Anton Goloborodko @golobor.bsky.social · 03/09/2026
1/ out in @science.org! We found a new asymmetry in large-scale chromosome structure: sister chromatids are shifted by hundreds of kb in the 5′→3′ direction of their inherited strands! A close collaboration w/ @gerlichlab.bsky.social , led by @flaviacorsi.bsky.social www.science.org/doi/10.1126/...
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Marlies Oomen @marliesoomen.bsky.social · 02/09/2026
Guess it's official now! #NewPI #TEsky #UMassChan
Picture shows the door to the office of Marlies Oomen at UMass Chan Medical School
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Max Farnworth @maxfarnworth.bsky.social · 31/08/2026
I am advertising a 3 year postdoc position. This person is going to focus on cell type development and evolution across key integration centres of the insect brain in four insect species. See details in the ad.
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Max Farnworth @maxfarnworth.bsky.social · 31/08/2026
I am also advertising a 4 year (!) PhD student position. The PhD student will design developmental brain atlases and help establish comparative projectomics in key cell groups of the central complex and mushroom bodies. See details in the ad.
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Max Farnworth @maxfarnworth.bsky.social · 31/08/2026
🚨 I AM HIRING a 3-year postdoc & 4-year PhD student 🚨 [PLEASE SHARE WIDELY] My Emmy Noether @dfg.de funded Neural Circuit & Systems Evolution lab (🌟) at the @unimainz.bsky.socialÍ wants to start existing. So..., what do we need? WELL... we need you! APPLY UNTIL 21 SEPTEMBER.
static.klipy.com
ALT:
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Tetsuya Yamada @tyamadat.bsky.social · 30/07/2026
Our manuscript on the co-option of TEs as cerebellar CREs is now officially published in @natcomms.nature.com! Huge thanks to @kaessmannlab.bsky.social @marisepp.bsky.social, and @ioansarr.bsky.social for the fantastic collaboration throughout this project! www.nature.com/articles/s41...
nature.com
Gene regulatory innovations from transposable elements in primate cerebellum development - Nature Communications
The roles of transposable elements in primate brain development remain underexplored. Here, the authors identify transposable elements with ancestral regulatory potential that have been co-opted as ci...
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Max Farnworth @maxfarnworth.bsky.social · 23/07/2026
----- PLS SHARE WIDELY ----- I have 2 positions to fill asap: 1) a 3-year postdoctoral position, creating single-cell atlases across species and development. 2) a 4-year (!) PhD position, to create anatomical atlases. Both will work together on integrating these two strands of information...!
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Max Farnworth @maxfarnworth.bsky.social · 23/07/2026
🚨 I am very happy (and relieved!) to announce that I secured Emmy Noether funding by the @dfg.de to start my own group at @unimainz.bsky.social , hosted by Marion Silies & Jakob von Engelhardt in August! 🚨 Website coming soon - open for name/logo suggestions. They better be funny tho!
static.klipy.com
Sophia Petrillo with Megaphone in Golden Girls
ALT: Sophia Petrillo with Megaphone in Golden Girls
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Jana Helsen @helsenjana.bsky.social · 16/07/2026
I am starting my lab at the University of Geneva next January! Incredibly excited to soon be joining the MOCEL department as an Asst. Professor. The lab will use evolutionary cell biology to study chromosomes, centromeres & speciation 🧬🔬🌱 Intrigued, want to join or collaborate? 🔗 helsenlab.org
helsenlab.org
Helsen lab | chromosome and centromere evolution
The Helsen lab at the University of Geneva explores how centromeres and chromosomes evolve, diversify, and function across eukaryotes. Discover our latest publications, research team, and open positio...
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Jakob Schnabl-Baumgartner @jakobschnabl.bsky.social · 07/07/2026
www.cell.com/molecular-ce... I'm happy to see our work published! If you are interested in transposons, transcriptional regulation and Pol III come and check it out 👀 🧫 🧬
cell.com
ChAHP silences SINE retrotransposons by inhibiting TFIIIB recruitment
SINEs are short transposable elements that make up large fractions of mammalian genomes. Known to be transcribed by RNA polymerase III, their regulation has remained largely unexplored. Schnabl-Baumga...
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Ethan (Chee Kiang) Ewe @ethanewe.bsky.social · 06/07/2026
This paper is now online at @currentbiology.bsky.social. This marks the end of my postdoc and I’ll be joining @imperiallifesci.bsky.social as Imperial College Research Fellow in October! 🎊 🥳🍾 www.cell.com/action/showP...
cell.com
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Job Dekker @jobdekker.bsky.social · 01/07/2026
Frank Grosveld has been a giant in the field of long-range gene regulation. Inspirational to me and I am sure for many others. Rest in peace.
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Mikko Taipale @miketilapia.bsky.social · 30/06/2026
Our evil ORFeome paper is out! In collaboration with @alex-stark.bsky.social, we screened ~4,000 viral proteins and secreted effectors from bacteria and parasites, covering hundreds of diverse pathogens, for phenotypes in human cells.
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Dfam Database of Transposable Elements @dfam.bsky.social · 25/06/2026
A New Open Foundation for TE Research: GIRI is transitioning the full Repbase collection to an open-access license and joining the Dfam effort to help build a unified open resource for transposable element research. Full announcement: tinyurl.com/48665xss
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Alex Eve @amjeve.uk · 24/06/2026
Noticeable underrepresentation of women as corresponding authors in the 1%. Almost as if AI has been trained on years of discriminatory behaviours and is perpetuating that bias.
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Alex Eve @amjeve.uk · 18/06/2026
Journal impact factors were released yesterday. In our latest @dev-journal.bsky.social Editorial, @jamesbriscoe.bsky.social and I discuss how we are all architects of impact, highlighting that measuring the influence and support journals provide goes beyond a single number. doi.org/10.1242/dev....
doi.org
The elephant in the room: impact factor
Summary: This Editorial offers an honest look at impact factor trends in developmental biology, explains how Development serves its community, and makes the case that sustaining developmental biology ...
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Albert and Mary Lasker Foundation @laskerfdn.bsky.social · 16/06/2026
Barbara McClintock was born #OTD in 1902. 🧪 🌽 McClintock, who spent most of her career at Cold Spring Harbor Laboratory, won a Basic Medical Research Lasker in 1981 for the discovery of transposons, genetic elements that can move from one location to another: ow.ly/hVNI50Jvkql #WomenInSTEM
Barbara McClintock in her later years, wearing a purple sweater and beige jacket, holding a multicolored ear of corn outdoors near greenery.Barbara McClintock in her later years conversing with a student in a dense cornfield.A black and white photograph of a young Barbara McClintock in a lab coat working with microscope slides and a microscope in a vintage laboratory setting.
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Dfam Database of Transposable Elements @dfam.bsky.social · 05/06/2026
Dfam 4.0 has been released. With over 7 million TE families spanning 6130 species, Dfam continues to grow through genome sequencing and community submissions. This release also introduces an improved FamDB format, making it easier to obtain only the data you need. Release notes: tinyurl.com/6dzwu4w8
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Cedric Feschotte @cedricfeschotte.bsky.social · 29/05/2026
📣 POSTDOC position available in the Feschotte Lab at Cornell to work on #TRANSPOSONS! More details below. Pls send informal application or inquiry ASAP by DM or email to cf458_at_cornell.edu. Pls spread the word 🙏 #TEsky www.thefeschottelabatcornell.com
thefeschottelabatcornell.com
The Feschotte Lab at Cornell
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Goeke Lab @goekelab.bsky.social · 11/05/2026
We are thrilled to release Bambu-pipe 🧬 🚀 A Nextflow pipeline built for speed, scalability, and precision — unlocking isoform-level insights from long-read single-cell and spatial RNA-seq data💡 🔗 GitHub: github.com/GoekeLab/bambu-pipe 📄 Preprint: doi.org/10.1101/2024.12.30.630828
github.com
GitHub - GoekeLab/bambu-pipe: Transcript discovery and quantification for long read single cell and spatial transcriptomics data using Bambu
Transcript discovery and quantification for long read single cell and spatial transcriptomics data using Bambu - GoekeLab/bambu-pipe
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Mathieu Lupien @matlupien.bsky.social · 05/05/2026
Excited to share our @natgenet.nature.com study showing that epigenetically rewired transposable elements control AML leukemia stem cell properties and patient outcome. Grateful to the team & collaborators. www.nature.com/articles/s41...
nature.com
Transposable elements shape stemness in normal and leukemic hematopoiesis - Nature Genetics
This study identifies distinct transposable element subfamilies as genetic determinants of stemness properties in normal and leukemic stem populations with clinical implications for patients with acut...
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Cedric Feschotte @cedricfeschotte.bsky.social · 07/05/2026
👋 Transposon lovers: registration is now open for the CSHL TE meeting! We have a 🔥 lineup of invited speakers and many slots for short talks selected upon abstract across all areas of TE biology. 🧬➰🧬 #TEsky Abstract deadline: July 10 meetings.cshl.edu/meetings.asp...
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Development @dev-journal.bsky.social · 23/04/2026
We are pleased to welcome 8 new fellows to our Pathway to Independence programme. Welcome Maëlle Bellec, @iamzico.bsky.social, @evhealy.bsky.social, @josepmercadal.bsky.social, @nikhil-mishra.bsky.social, Jessica Perochon, Yamini Ravichandran & Margherita Zamboni. Read more⤵️ tinyurl.com/4bk4wrk7
Maëlle Bellec, Swarnabh Bhattacharya, Evan Healy, Josep Mercadal, Nikhil Mishra, Jessica Perochon, Yamini Ravichandran and Margherita Zamboni.
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The EMBO Journal @embojournal.org · 23/03/2026
Which transcription factors control transposable element expression during zygotic genome activation? Gain-of-function screen by @metorrespadilla.bsky.social and coworkers identifies TBP as direct regulator of mouse endogenous retrovirus-like elements link.springer.com/article/10.1...
link.springer.com
TBP regulates transposable element expression in early mouse embryos - The EMBO Journal
The activation of the embryonic genome is a crucial step in development. In addition to thousands of genes, many transposable elements (TEs) are robustly transcribed during early mammalian development...
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ME Torres-Padilla @metorrespadilla.bsky.social · 20/03/2026
Just out! 👀 for TFs that regulate TEs.Clara's work with @tamas-schauer.bsky.social @marliesoomen.bsky.social @palmrinmoy.bsky.social and bluesky-less lab members 🌎 identifies TBP as a regulator of specific ERVL class: MaLRs in 🐭embryos -as always -feedback welcome👍 link.springer.com/article/10.1...
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Yinan Wan @yinanwan.bsky.social · 12/03/2026
Very grateful to everyone who made this work possible. I feel incredibly lucky to have worked with such an amazing team. Special thanks to: Jakob El Kholtei, KJ Jenie, @mcolomerr.bsky.social, and of course our wonderful collaborator Bogdan Bintu and my mentor @schierlab.bsky.social
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Sarah Hainer @hainerlab.bsky.social · 27/02/2026
Incredibly proud to share our new preprint, lead by the Incomparable Rithika Sankar. Here we temporally dissect the role of FACT in mES cells, finding that FACT loss drives progressive deterioration of chromatin architecture, leading to transcriptional collapse. www.biorxiv.org/content/10.6...
biorxiv.org
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Margarida Cardoso Moreira @margaridamcm.bsky.social · 25/02/2026
Our internal organs are evolutionary marvels. New technologies are transforming our understanding of the evolution of vertebrate organs. You can find more by reading here: rdcu.be/e5EgU #EvoBio #EvoDevo 🐟🦎🐢🦇🐊🦜
rdcu.be
The molecular evolution of vertebrate organs
Nature Ecology & Evolution - This Review discusses recent advances in the molecular evolution of vertebrate organs, including rates of evolution of organs and cell types, molecular mechanisms...
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Miles Huseyin @mileshuseyin.bsky.social · 19/02/2026
I had a lot of fun putting this together with @suminkim.bsky.social and @andersshansen.bsky.social! Glad to have had the chance to work on it!
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MwahahahahahadScientist @mads100tist.bsky.social · 16/02/2026
I am also (i) very stressed, (ii) very thrilled and (iii) on the job market
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MwahahahahahadScientist @mads100tist.bsky.social · 16/02/2026
PEOPLES OF EARTH: BE PREPARED 🧪
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Rafael D. Acemel @rdacemel.bsky.social · 02/02/2026
New preprint!! 🚨 Did you know that many vertebrate species determine sex based on environmental conditions rather than chromosomes? Some turtles, like Trachemys scripta, rely on temperature. We learned more about how this happen molecularly.👇 www.biorxiv.org/content/10.6...
biorxiv.org
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Ioannis Sarropoulos @ioansarr.bsky.social · 30/01/2026
The final (and my favorite) chapter of my PhD is now officially published! Extremely grateful to all our collaborators, especially to @marisepp.bsky.social and @tyamadat.bsky.social for their hard work, and to @steinaerts.bsky.social and @kaessmannlab.bsky.social for their guidance and advice!
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Danica Milovanović @1995dana.bsky.social · 29/01/2026
It is finally out! If you are interested in TE-derived CREs, and newly described, but evolutionary old KZFP-TE mechanistic modalities, read it at www.cell.com/cell-reports.... Thankful to everyone who took part in this work, namely @orpsf.bsky.social and other @trono-lab.bsky.social members. 🫀🧬✨
cell.com
Tissue-specific restriction of transposon-derived regulatory elements safeguards cell-type identity
Milovanović et al. uncover a mechanism by which KZFPs restrict the activity of transposon-derived cis-regulatory elements to safeguard cardiomyocyte functionality. This work extends the classical TE-K...
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Giulia Paci @giuliapaci.bsky.social · 22/01/2026
Very excited to receive this award and truly grateful to the @bscb-official.bsky.social who have been supporting me throughout my postdoc since I moved to the UK!
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Tay (Antonio J. Osuna Mascaró) @biotay.bsky.social · 19/01/2026
Cow Tools! We have lived alongside cows for nearly 10,000 years. We breed them and exploit them It is now, only now, that we have discovered THEY CAN USE TOOLS Here I describe our study (paper) www.sciencedirect.com/science/arti... in @currentbiology.bsky.social with @auersperga.bsky.social
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UMass Chan Medical School @umasschan.bsky.social · 12/01/2026
Work by the 4D Nucleome Consortium, led by Job Dekker, PhD, reveals a systematic map of the structure and function of the human: direc.to/ooab #genome @jobdekker.bsky.social @hhmi-science.bsky.social @nature.com @marionicodemi.bsky.social @creminslab.bsky.social @gladstoneinst.bsky.social
direc.to
4D Nucleome Consortium produces detailed models of the 3D genome over time in cells
The 4D Nucleome Consortium has extensively mapped and analyzed the 3-D folding of the human genome in human embryonic stem cells and immortalized fibroblasts over time.
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Ethan (Chee Kiang) Ewe @ethanewe.bsky.social · 11/01/2026
I’ve been so lucky to be part of the PI Programme by @biologists.bsky.social this past year and met so many incredible people! Come hear us talk about what keeps us up at night this Wednesday!
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