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Goeke Lab

@goekelab.bsky.social
57 followers 84 following 24 posts

Göke Lab | Genome Institute of Singapore, A*STAR AI | Computational Transcriptomics | Long Read RNA Technologies github.com/GoekeLab

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Goeke Lab @goekelab.bsky.social · 15/09/2026
This week our team joins the 5th Undiagnosed Hackathon in Singapore, hosted by KK Women's and Children's Hospital, pioneered by the Wilhelm Foundation. 🧬
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Goeke Lab @goekelab.bsky.social · 02/09/2026
We've released xPore v2.2. This version adds support for genome-aligned dRNA-seq reads (previously xPore required transcriptome aligned reads). This is a beta feature, feedback and bug reports via GitHub issues are very welcome! github.com/GoekeLab/xpo...
github.com
Release xPore v2.2 · GoekeLab/xpore
Summary This release adds: Genome-alignment support: xPore previously only worked with transcriptome-aligned reads. A new --kmer_source flag on dataprep allows genome-aligned input (handling rever...
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Goeke Lab @goekelab.bsky.social · 18/08/2026
Two more days until the Singapore RNA Salon mentorship event! There are still places left, a great opportunity to chat 1-on-1 with scientists about how they've built their careers! Event information: www.a-star.edu.sg/gis/news-eve... Registration here: form.gov.sg/6a754173a89c...
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Goeke Lab @goekelab.bsky.social · 05/08/2026
New release of our Awesome Genomic Skills list is out! Now featuring roda-mcp (AWS dataset discovery), Kiro's life-sci skills, ClawBio's new MCP mode, and a community-contributed plant-genomics MCP. PRs welcome! github.com/GoekeLab/awesome-genomic-skills
github.com
GitHub - GoekeLab/awesome-genomic-skills: A curated list of awesome genomics and bioinformatics agentic skills, MCPs and benchmarks for Claude Code, Copilot, Codex, Cursor, Gemini CLI, etc
A curated list of awesome genomics and bioinformatics agentic skills, MCPs and benchmarks for Claude Code, Copilot, Codex, Cursor, Gemini CLI, etc - GoekeLab/awesome-genomic-skills
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FEBS Letters @febsletters.bsky.social · 29/07/2026
The complex life of RNA EMBO | EMBL Symposium is taking place 13 - 16 Oct 2026 in Heidelberg AND virtually! Register by 1 September for on-site attendance here: www.embl.org/about/info/c... #RNA #RNAbiology @events.embl.org @embo.org @embl.org
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Goeke Lab @goekelab.bsky.social · 27/07/2026
The 2nd Workshop of the Human RNome Project Consortium took place last week in sunny Toronto 🇨🇦 ☀️, and @clare-r.bsky.social from our team had the pleasure of attending and hearing about the fantastic work happening all over the globe on #RNA modifications.
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Janusz M. Bujnicki @jmbujnicki.bsky.social · 25/10/2025
Exciting news for the RNA research community! The Human RNome Project has been launched: a global effort to map all human RNAs and their chemical modifications. Proud to support it and contribute to the article in Genome Biology doi.org/10.1186/s130... #RNA #bioinformatics #RNAstructure #modomics
genomebiology.biomedcentral.com
Unlocking the regulatory code of RNA: launching the Human RNome Project - Genome Biology
The human RNome, the complete set of RNA molecules in human cells, arises through complex processing and includes diverse molecular species. While research traditionally focuses on four canonical nucl...
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A*STAR Genome Institute of Singapore (A*STAR GIS) @astar-gis.bsky.social · 23/07/2026
Congratulations to Dr @jonathangoeke.bsky.social on being awarded the National Research Foundation (NRF) Investigatorship 2026! Presented by NRF Singapore, the award supports outstanding scientists and researchers in pursuing groundbreaking, high-risk research. @goekelab.bsky.social
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Goeke Lab @goekelab.bsky.social · 23/06/2026
New in Bambu-Pipe: batch effect correction now integrated into clustering for long-read single-cell & spatial RNA-seq Integrate samples across ONT & PacBio, combine 10x 3'/5' chemistries, and get clusters that reflect biology, not technical artifacts. github.com/GoekeLab/bambu-pipe
Two UMAP plots comparing ONT and PacBio long-read single-cell data before and after batch correction. Left panel (No Correction): ONT (red) and PacBio (cyan) cells form separate, non-overlapping clusters, indicating platform-driven grouping. Right panel (Batch Corrected): ONT and PacBio cells overlap within the same clusters, showing successful integration where cells group by cell type rather than sequencing platform.
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Goeke Lab @goekelab.bsky.social · 16/06/2026
The 2nd Singapore RNA Salon is just 2 days away! We'll have talks from Early Career Researchers, snacks for networking and a *shuttle bus* to help transport attendees from NUS & A*STAR to NTU! Make sure to register to secure your spot (and receive the bus details!): form.gov.sg/69c0965ce982...
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Jonathan Göke @jonathangoeke.bsky.social · 12/06/2026
Applications are open for the Singapore Open Research Awards 2026. The awards recognise researchers for open, transparent, and reusable research with meaningful impact. Nominate someone or apply here libguides.ntu.edu.sg/SGORawards2026
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Goeke Lab @goekelab.bsky.social · 11/06/2026
We'll be at the NIRBA RNA Science Conference 2026! 🧬 🗓️ 22–23 Oct 2026 | 📍 Singapore Our lab is part of @NIRBA_sg Cluster 2 — RNA modifications & host immunity. Looking forward to the science and the community! #RNAScience #NIRBA #SaveTheDate
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Goeke Lab @goekelab.bsky.social · 09/06/2026
We’ve updated our awesome-nanopore list! The list is a community-curated list of ONT software tools, please feel free to check it out & contribute: github.com/GoekeLab/awesome-nanopore #Nanopore #Bioinformatics #LongReadSequencing
github.com
GitHub - GoekeLab/awesome-nanopore: A curated list of awesome nanopore analysis tools.
A curated list of awesome nanopore analysis tools. - GoekeLab/awesome-nanopore
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Goeke Lab @goekelab.bsky.social · 03/06/2026
2 weeks until the 2nd Singapore RNA Salon! Abstracts for the talks are below ⬇️ The event is open to everyone, from undergrads to PIs, hope to see you there! Registration: form.gov.sg/69c0965ce982...
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Goeke Lab @goekelab.bsky.social · 29/05/2026
AI is changing how science (& genomics!) gets done. 🧬 Check out our new "awesome" repo - a curated list of skills, MCP servers & benchmarks for AI agents in bioinformatics. Open source & open for contributions! github.com/GoekeLab/awe...
github.com
GitHub - GoekeLab/awesome-genomic-skills: A curated list of awesome genomics and bioinformatics agentic skills, MCPs and benchmarks for Claude Code, Copilot, Codex, Cursor, Gemini CLI, etc
A curated list of awesome genomics and bioinformatics agentic skills, MCPs and benchmarks for Claude Code, Copilot, Codex, Cursor, Gemini CLI, etc - GoekeLab/awesome-genomic-skills
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Goeke Lab @goekelab.bsky.social · 29/05/2026
AI is changing how science (& genomics!) gets done. 🧬 Check out our new "awesome" repo - a curated list of skills, MCP servers & benchmarks for AI agents in bioinformatics. Open source & open for contributions! github.com/GoekeLab/awe...
github.com
GitHub - GoekeLab/awesome-genomic-skills: A curated list of awesome genomics and bioinformatics agentic skills, MCPs and benchmarks for Claude Code, Copilot, Codex, Cursor, Gemini CLI, etc
A curated list of awesome genomics and bioinformatics agentic skills, MCPs and benchmarks for Claude Code, Copilot, Codex, Cursor, Gemini CLI, etc - GoekeLab/awesome-genomic-skills
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Goeke Lab @goekelab.bsky.social · 25/05/2026
🙌 Excited to share Bambu and our findings on the new long-read cDNA kit from Oxford Nanopore Technologies — featured at London Calling 2026. Full story at the RNA 2026 Pre-Meeting Workshop, Montreal! 🇨🇦 @nanoporetech.com @rnasociety.bsky.social #RNA2026 #OxfordNanopore #Bambu
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Jonathan Göke @jonathangoeke.bsky.social · 22/05/2026
The new long read cDNA kit by @nanoporetech.com is a major upgrade (and improvement!), substantially increasing read length, with a strong impact on transcript discovery and quantification. We @goekelab.bsky.social have tested this in the beta release, more updates soon #nanoporeconf
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Goeke Lab @goekelab.bsky.social · 21/05/2026
🧬 Join us for the 2nd Singapore RNA Salon! 📅 June 18th, 4–6 PM📍 NTU 3 talks from ECRs covering mitochondrial dsRNA & inflammation, engineered CasRx RNA editing and long-read single-cell & spatial RNA-seq followed by snacks and networking, all are welcome! ⭐ Link & more info in comments
form.gov.sg
Registration: Singapore RNA Salon: 18th June 16:00 - 18:00, NTU, School of Biological Sciences
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Goeke Lab @goekelab.bsky.social · 13/05/2026
Great trip to Fukuoka with PacBio! 🚀 Sui Yue is on-site, presenting bambu and representing the lab. Hands-on feedback always welcome — let’s discuss!💡 🔗 GitHub: github.com/GoekeLab/bambu 🔗 GitHub: github.com/GoekeLab/bambu-pipe 📄 Preprint: doi.org/10.1101/2024.12.30.630828
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Goeke Lab @goekelab.bsky.social · 11/05/2026
We are thrilled to release Bambu-pipe 🧬 🚀 A Nextflow pipeline built for speed, scalability, and precision — unlocking isoform-level insights from long-read single-cell and spatial RNA-seq data💡 🔗 GitHub: github.com/GoekeLab/bambu-pipe 📄 Preprint: doi.org/10.1101/2024.12.30.630828
github.com
GitHub - GoekeLab/bambu-pipe: Transcript discovery and quantification for long read single cell and spatial transcriptomics data using Bambu
Transcript discovery and quantification for long read single cell and spatial transcriptomics data using Bambu - GoekeLab/bambu-pipe
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Goeke Lab @goekelab.bsky.social · 20/04/2026
🚀 1 Hackathon. 3 days! A ton of fun and brain-storming! Huge thanks to the team! 💻✨ Check out our GitHub page for the tools we developed: 🔗 github.com/GoekeLab And the lab website for the team: 🌐 jglab.org #ScienceSky #Hackathon #OpenSource #ResearchComputing🚀💻
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