Although hundreds of viral transcriptional regulators (vTRs) have been identified, we know little about the host pathways they rewire to promote replication and persistence or their mechanisms of action.
In our new paper, we addressed this gap across human viruses. 🧵
www.nature.com/articles/s41...
nature.com
Functional characterization of viral transcriptional regulators reveals extensive rewiring of host pathways - Nature Communications
The authors here show how viral transcriptional regulators reprogram human gene activity through diverse mechanisms, revealing shared strategies used by different viruses to control host pathways and ...