Translational perturbations trigger ubiquitination and turnover of 40S ribosomes, yet how these events are coupled remains unclear. Shah et al. reveal that RIOK3 remodels ubiquitinated 40S subunits, e...

Be white and Christian, or America doesn’t want you.

“It’s a wholly unethical trial, and it shouldn’t be allowed,” says Dr. Paul Offit of Guinea-Bissau study

Tsai et al. discover that ribosome composition is reprogrammed in response to intrinsic and external cellular perturbations, which supports ribosome remodeling as a conserved mechanism that enables ad...

Proposition 38 will award $4 billion to one unnamed research center. Under the very specific criteria, only one center seemingly qualifies.

In short:

Alt: Patrick Stewart's Mild Shock Reaction

The U.S. prison population is declining at an accelerating rate, and prison admission rates are predicted to fall an additional 50% within the next two decades, according to new research from Universi...

Ribosome hibernation helps cells survive stress by reversibly silencing translation and preserving ribosomal complexes. Although well characterized in bacteria and eukaryotes, archaeal hibernation rem...

Ribosome hibernation helps cells survive stress by reversibly silencing translation and preserving ribosomal complexes. Although well characterized in bacteria and eukaryotes, archaeal hibernation rem...

The paper’s editorial vision is out of step with the robust liberalism needed today.

Cryogenic electron microscopy (cryo-EM) has enabled rapid progress in structural biology throughout the last decade. However, cryo-EM sample preparation still represents a major bottleneck in high-res...

BACH2 restrains activation of the fetal-haemoglobin-encoding γ-globin genes, while loss of BACH2 enhances NRF2 chromatin occupancy and promotes the formation of activation foci at the γ-globin genes.

YouTube video by Aaron Attaboy McAvoy